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Acetazolamide May Help COPD Patients Reach New Heights
(MedPage Today) -- Acetazolamide may prevent some patients with chronic obstructive pulmonary disease (COPD) from suffering altitude-related adverse health effects (ARAHE) when traveling, a randomized controlled trial showed.
In patients with...
Source: MedPage Today Allergy - September 14, 2023 Category: Allergy & Immunology Source Type: news
Fake Sudafed is bullshit, just as you suspected
Two decades ago, it became clear that Congress was intent on trying to curtail illicit methamphetamine production by restricting access to pseudoephedrine, a meth precursor that was also widely used as a decongestant in cold and allergy remedies such as Sudafed. Pfizer, the manufacturer of Sudafed…#johnsonjohnson #pfizer #fda #oregon #mississippi #mexican #uspharmacist #reasoncom
Source: Reuters: Health - September 13, 2023 Category: Consumer Health News Source Type: news
Early Oophorectomy May Accelerate Onset of Chronic Health Problems
(MedPage Today) -- The removal of both ovaries before menopause was associated with a higher likelihood of chronic health conditions and worse physical function years later, especially for women who underwent the procedure early, a cross-sectional...
Source: MedPage Today Allergy - September 13, 2023 Category: Allergy & Immunology Source Type: news
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Immune Dysfunction from Radiation Exposure
Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-22-00197.1. Online ahead of print.ABSTRACTExposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced resistance to infections and hemorrhage. Besides these acute effects, tissue damage from radiation can trigger inflammatory responses, leading to progressive and chronic tissue damage by radiation-induced loss of immune cell types that are required for resolving tissue injuries. Understanding the mechanisms involved in radiation-induced immune system injury and repair will provide new insig...
Source: Radiation Research - September 13, 2023 Category: Physics Authors: David R Cassatt Thomas A Winters Mercy PrabhuDas Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Immune Dysfunction from Radiation Exposure
Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-22-00197.1. Online ahead of print.ABSTRACTExposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced resistance to infections and hemorrhage. Besides these acute effects, tissue damage from radiation can trigger inflammatory responses, leading to progressive and chronic tissue damage by radiation-induced loss of immune cell types that are required for resolving tissue injuries. Understanding the mechanisms involved in radiation-induced immune system injury and repair will provide new insig...
Source: Radiation Research - September 13, 2023 Category: Physics Authors: David R Cassatt Thomas A Winters Mercy PrabhuDas Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Expert opinion on management of moderate-to-severe atopic dermatitis in Qatar
J Dermatolog Treat. 2023 Dec;34(1):2251622. doi: 10.1080/09546634.2023.2251622.ABSTRACTAtopic dermatitis (AD), a chronic-relapsing inflammatory skin disorder, manifests with intense itching and eczematous lesions impairing quality of life. A heterogeneous population, and regional clinical practices for treating AD warrant the development of guidelines in Qatar. Therefore, guidelines for the management of moderate-to-severe AD in Qatar have been developed and discussed. Experts, including dermatologists and immunologists, used the Delphi technique for developing guidelines. Consensus was defined as ≥75% agreement or disag...
Source: Journal of Dermatological Treatment - September 13, 2023 Category: Dermatology Authors: Martin Steinhoff Mehdi Adeli Hassan Riad Mohamed Allam Ahmad Hazem Ra'ed Alsmadi Adel Mohamed Kamal Waad Ibrahim Maryam Ali Al-Nesf Source Type: research
Immune Dysfunction from Radiation Exposure
Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-22-00197.1. Online ahead of print.ABSTRACTExposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced resistance to infections and hemorrhage. Besides these acute effects, tissue damage from radiation can trigger inflammatory responses, leading to progressive and chronic tissue damage by radiation-induced loss of immune cell types that are required for resolving tissue injuries. Understanding the mechanisms involved in radiation-induced immune system injury and repair will provide new insig...
Source: Cell Research - September 13, 2023 Category: Cytology Authors: David R Cassatt Thomas A Winters Mercy PrabhuDas Source Type: research
Toxoplasmosis mimicking CMV chorioretinitis in newly diagnosed PLWH: a case report
CONCLUSIONS: despite progressive developments in the management of PLWH, in this case two different kind of opportunistic infection are found in a late-presenter patient. In particular, two aspects can be highlighted. The first one is that, in the setting of an highly impaired immune system, clinical presentation can be deceptive and more than one opportunistic infection can be observed together in the same patient. The second aspect is that after starting antiretroviral therapy, a rapid improvement of viro-immunologic parameters has been documented, probably leading to an immune reconstitution inflammatory syndrome (IRIS)...
Source: Infezioni in Medicina - September 13, 2023 Category: Infectious Diseases Authors: Francesco Lamanna Rosa Anna Passerotto Andrea Carbone Rebecca Jo Steiner Valentina Iannone Pierluigi Francesco Salvo Arturo Ciccullo Gianmaria Baldin Alberto Borghetti Alex Dusina Source Type: research
Expert opinion on management of moderate-to-severe atopic dermatitis in Qatar
J Dermatolog Treat. 2023 Dec;34(1):2251622. doi: 10.1080/09546634.2023.2251622.ABSTRACTAtopic dermatitis (AD), a chronic-relapsing inflammatory skin disorder, manifests with intense itching and eczematous lesions impairing quality of life. A heterogeneous population, and regional clinical practices for treating AD warrant the development of guidelines in Qatar. Therefore, guidelines for the management of moderate-to-severe AD in Qatar have been developed and discussed. Experts, including dermatologists and immunologists, used the Delphi technique for developing guidelines. Consensus was defined as ≥75% agreement or disag...
Source: Journal of Dermatological Treatment - September 13, 2023 Category: Dermatology Authors: Martin Steinhoff Mehdi Adeli Hassan Riad Mohamed Allam Ahmad Hazem Ra'ed Alsmadi Adel Mohamed Kamal Waad Ibrahim Maryam Ali Al-Nesf Source Type: research
Staphylococcus aureus Enterotoxin B Is a Cofactor of Food Allergy beyond a Superantigen
J Immunol. 2023 Sep 13:ji2200549. doi: 10.4049/jimmunol.2200549. Online ahead of print.ABSTRACTStaphylococcus aureus enterotoxin B (SEB), one of the most common bacterial toxins in food contamination, has been poorly understood in relationship to food allergy outcomes. To investigate whether the ingestion of enterotoxins in food allergens could affect the development of food allergy, OVA-sensitized female BALB/c mice were challenged with OVA added with different doses of SEB or LPS. Allergic symptoms, such as diarrhea rate and hypothermia, could be aggravated in mice challenged with OVA and a low dose of SEB. The increased...
Source: Journal of Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Jin Yuan Ping Tong Zhongliang Wang Xiaoqian Xu Xiaoli Zhao Xuanyi Meng Yong Wu Xin Li Jinyan Gao Hongbing Chen Source Type: research
