Possibility of SARS-CoV-2 transmission from the breast milk of COVID-19 affected women patients to their infants: worries and strategies to counter it.
Authors: Patel SK, Pathak M, Rana J, Tiwari R, Natesan S, Dhama J, Malik YS, Rodriguez-Morales AJ, Dhama K, Pagliano P Abstract Not available. PMID: 32920563 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Chest computed tomography findings in hospitalized COVID-19 patients: a systematic review and meta-analysis.
Authors: Muhammad SZ, Ahmed A, Shahid I, Khalid A, Menezes RG, Sheikh MU, Siddiqi TJ, Usman MS, Khosa F Abstract Most studies evaluating chest computed tomography (CT) features in coronavirus disease 2019 (COVID-19) have been small-sized and have presented varied findings. We aim to systematically review these studies and to conduct a meta-analysis of their results to provide a well-powered assessment of chest CT findings in patients with COVID-19. PubMed and EMBASE databases were systematically searched to identify published studies that evaluated chest CT findings in COVID-19 patients. Data regarding study charac...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Natural selection versus creation: a review on the origin of SARS-COV-2.
Authors: Barh D, Silva Andrade B, Tiwari S, Giovanetti M, Góes-Neto A, Alcantara LCJ, Azevedo V, Ghosh P Abstract SARS-CoV-2 has created a global disaster by infecting millions of people and causing thousands of deaths across hundreds of countries. Currently, the infection is in its exponential phase in several countries and there is no sign of immediate relief from this deadly virus. At the same time, some "conspiracy theories" have arisen on the origin of this virus due to the lack of a "definite origin". To understand if this controversy is also reflected in scientific publications, he...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Epidemiology of Pseudomonas aeruginosa in cystic fibrosis patients in Iran: A systematic review and meta-analysis.
Authors: Alavi Foumani A, Yaghubi Kalurazi T, Mohammadzadeh Rostami F, Sedigh Ebrahim-Saraie H, Nazari-Alam A, Halaji M Abstract The present study aims to investigate the prevalence of Pseudomonas aeruginosa in Iranian Cystic Fibrosis (CF) patients. We conducted a systematic search on this topic in Web of Science, PubMed, Embase, Scopus, and Google Scholar electronic databases to the end of July 2019. Then, 14 articles with eligible criteria were selected for data extraction and analysis by Comprehensive Meta-Analysis Software. The pooled prevalence of P. aeruginosa was 40.6% (95% CI: 32.4%-49.4%) ranging from 32.4...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Bacteriophage therapy: an overview and the position of Italian Society of Infectious and Tropical Diseases.
Authors: Cesta N, Di Luca M, Corbellino M, Tavio M, Galli M, Andreoni M Abstract In recent years, the increase of antibiotic resistance and the lack in the pipeline of novel antimicrobial molecules make bacterial infections difficult to treat. Among European countries, Italy is the one region with a higher number of deaths caused by antibiotic-resistant bacteria. Moreover, a major concern is represented by biofilm-related infections. The ability of bacteria to form biofilm in presence of implanted-medical devices represents a further challenge for the treatment of bacterial infections. Thus, the development of alte...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Past and current advances in Marburg virus disease: a review.
Authors: Asad A, Aamir A, Qureshi NE, Bhimani S, Jatoi NN, Batra S, Ochani RK, Abbasi MK, Tariq MA, Diwan MN Abstract Marburg Virus (MARV), along with the Ebola virus, belongs to the family of Filovirus and is cause of a lethal and severely affecting hemorrhagic fever. The Marburgvirus genus includes two viruses: MARV and Ravn. MARV has been recognized as one of utmost importance by the World Health Organization (WHO). The case fatality rate of the virus ranges from 24.0 to 88.0% which demonstrates its lethal nature and the need for its widespread information. The first case of the Marburgvirus disease (MARD) was r...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Use of lung ultrasound in COVID-19: comparison with ultra-high-resolution computed tomography among 29 patients at "D. Cotugno" hospital, Naples, Italy.
Use of lung ultrasound in COVID-19: comparison with ultra-high-resolution computed tomography among 29 patients at "D. Cotugno" hospital, Naples, Italy. Infez Med. 2020 Sep 01;28(3):346-350 Authors: Iodice V, Pisaturo M, Fusco FM, Tambaro O, Parrella G, Di Flumeri G, Viglietti R, Pisapia R, Palmiero G, Bignardi E, Coppola M, Rescigno C, Sangiovanni V Abstract Ultra-High-Resolution Computed Tomography (U-HR-CT) is the reference imaging technique for pneumonia in the new coronavirus disease (COVID-19). Pulmonary Ultrasound (LUS) could be a valid diagnostic alternative for the imaging of COVID-1...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Out-patient management of patients with COVID-19 on home isolation.
Authors: Ayaz CM, Dizman GT, Metan G, Alp A, Unal S Abstract The rapidly increased number of patients with COVID-19 resulted in the shortage of hospital beds. An outpatient follow-up plan was developed for COVID-19 patients with stable clinical condition and no concomitant diseases. The records of COVID-19 first admission clinic were retrospectively reviewed to identify the COVID-19 patients who were followed on home isolation as outpatients between March 17, 2020 and April 18, 2020 in Ankara, Turkey. Demographic and clinical characteristics of the patients, compliance with isolation rules, re-admission rates, and ...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

The therapeutic potential of convalescent plasma therapy on treating critically-ill COVID-19 patients residing in respiratory care units in hospitals in Baghdad, Iraq.
Authors: Rasheed AM, Fatak DF, Hashim HA, Maulood MF, Kabah KK, Almusawi YA, Abdulamir AS Abstract The current COVID-19 pandemic needs unconventional therapies to tackle the resulted high morbidity and mortality. Convalescent plasma is one of the therapeutic approaches that might be of benefit. Forty nine early-stage critically-ill COVID-19 patients residing in Respiratory Care Units (RCU) of three hospitals in Baghdad, Iraq, were included: 21 received convalescent plasma while 28, namely control group, did not receive it. Recovery or death, length of stay in hospital, and improvement in the clinical course of the ...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Impact of trainee-driven Antimicrobial Stewardship Program in a high burden resource-limited setting.
Authors: Banerjee S, Gupta N, Ray Y, Kodan P, Khot WY, Fazal F, Nyas VKM, Soneja M, Vikram N, Biswas A, Kapil A, Wig N Abstract Antimicrobial Stewardship Program (ASP) is one of the most critical interventions required to halt the growing global antimicrobial resistance. The study aimed to evaluate the effect of trainee driven ASP implementation with limited available resources on outcome variables. An ASP team comprising of infectious diseases trainees and consultants was constituted to conduct stewardship activities in the Department of Medicine, All India Institute of Medical Sciences, a tertiary care apex insti...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Molecular detection of Anaplasma spp. in domestics dogs from urban areas of Soledad, Atlantico, Colombia.
Authors: Bonilla-Aldana DK, Pomares-Cantillo LH, Beltrán-Sánchez CA, Bettin-Martínez AC, Campo-Urbina ML, Rodriguez-Morales AJ, Pérez-Doria A Abstract Tick-borne pathogens are etiological agents of some zoonotic diseases, causing important consequences in animal and human health. These are emerging around the world, especially in tropical countries including Colombia. Domestic dogs play an essential role in the epidemiology of several zoonotic tick-borne pathogens. We performed the detection of bacteria from Anaplasmataceae family and parasites from the Piroplasmida order, in 85 domestic...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Sexually transmitted infections in male prison inmates. Prevalence, level of knowledge and risky behaviours.
This study aimed to assess prevalence of STIs, risky behaviours and STIs level of knowledge in male inmates of the Casa Circondariale-Genova Marassi, the main penitentiary in Genoa, Italy. Between January and June 2019, 662 inmate medical records were retrospectively examined to obtain clinical and laboratory data about STIs. To investigate the inmate level of knowledge of STIs and their risky behaviours, 111consenting participants answered, anonymously, a written questionnaire. One hundred and twenty-two patients had at least one infectious disease when entered the prison: HIV (1.8%), HBV (2.7%), HCV (12.5%) and syphilis ...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Fungal profile and antifungal susceptibility pattern in patients with oral candidiasis.
Authors: Sav H, Altinbas R, Dursun ZB Abstract Oral candidiasis is a common fungal infection, affecting the oral mucosa. The aim of this study was to investigate the epidemiology and antifungal susceptibility of Candida species isolated from the oral cavity of patients affected by oral candidiasis. Oral swabs were taken from 34 patients and were inoculated on to Sabouraud Dextrose Agar (SDA). The yeasts were preliminarily evaluated according to the growth (human serum) germ tube, chlamydospore formation, reproduction at 45 degrees C and colony characteristics on SDA medium. The commercial method Phoenix (Becton Dic...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Results of comprehensive cardiovascular diagnostic work-up in HIV positive patients.
Authors: Pontecorboli G, Lagi F, Bagli M, De Vito E, Millotti G, Botta A, Cappelli F, Mattesini A, Acquafresca M, Barletta G, Del Bene R, Colagrande S, Marcucci R, Bartoloni A, Di Mario C, Martinelli CV Abstract Cardiovascular disease (CVD) in the HIV population accounts for a large proportion of morbidity and mortality and, with the increased life expectancy, the burden of CVD is expected to rise. Inflammation, immune dysfunction, side effects of HIV medications, high prevalence of other risk factors are the likely pathogenic mechanisms for accelerated atherosclerosis. We aimed to evaluate the diagnostic yield of ...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Seroepidemiology of seasonal influenza virus among unvaccinated pregnant women in Lagos, Nigeria.
This study revealed that seasonal influenza circulates with co-morbidities in pregnant women in Lagos. This may exacerbate their immunosuppressed state and lead to complication in pregnancy. Apt treatment of influenza-like illness should be considered in such women. Furthermore, there is need for enhanced surveillance including monitoring of the potential transmissibility of influenza to the foetus and newborns. We therefore recommend sturdy advocacy on preventing exposure to influenza virus, its optimal early diagnosis, vaccination and disease management in pregnancy. PMID: 32920577 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

SARS-CoV-2 and Dengue virus Co-infection. A Case Report.
We report a confirmed case with favourable outcome, but whether the occurrence of simultaneous infections may alter the usual clinical course of each infection is still unknown. PMID: 32920578 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Xpert MTB/RIF for diagnosis of tubercular liver abscess. A case series.
Authors: Agarwala R, Dhooria S, Khaire NS, Mishra S, Verma S, Shah J, Mandavdhare HS, Kumari S, Dutta U, Sharma V Abstract Hepatic involvement is an infrequent manifestation of abdominal tuberculosis and could occur in form of granulomatous hepatitis, nodular involvement or abscess formation. Tubercular liver abscess (TLA) is uncommon, and diagnosing this entity is a challenge. Xpert MTB/RIF (Cepheid, Sunnyvale, CA, USA) assay has been widely used for diagnosing pulmonary tuberculosis (TB) and lymph nodal tuberculosis. Its utility in some forms of other extrapulmonary TB has also been studied. The role of Xpert MTB...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Non tuberculous mycobacteria related spondylodiscitis: a case report and systematic literature review.
Conclusion: This review highlights the rarity of spinal infections due to NTM and the difficulty of their management. A tailored approach with prolonged antibiotic therapy, eventually associated with surgery in selected cases were suggested for the treatment of NTM infections. PMID: 32920580 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

A case of crusted scabies with a delayed diagnosis and inadequate therapy.
Authors: Bonazzetti C, Pagani G, Giacomelli A, Morena V, Bassoli C, Corbellino M, Bestetti G, Galimberti L, Grande R, Antinori S Abstract Crusted scabies is an infrequent disease caused by Sarcoptes scabiei that usually affects patients with underlying medical conditions leading to immunosuppression. Here, we present the case of an 81 years old man, diagnosed with crusted scabies who came to our attention after multiple misdiagnosis and incorrect and potentially detrimental treatment with steroids. He was admitted to our inpatients ward and treated with oral ivermectin plus local permethrin. The hospitalization was...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

El Alamein: the battle in the battle. How infectious disease management changed the fate of one of the most important battle of the World War II.
Authors: Simonetti O, Armocida E Abstract El Alamein, on Egypt's Mediterranean coast, was the theater of war for one of the most important and decisive battles of the Second World War. The Allied victory in November 1942 opened the end of the Western Desert Campaign. The battle revived the morale of the Allies, being the first big success against the Axis since Operation Crusader in late 1941. The German threat to Egypt, the Suez Canal and the Middle Eastern and Persian oil fields was eliminated and the doors for Mediterranean advance were opened. Fighting in the desert under extreme human conditions exposed all th...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

The Early Report of Herpetic Whitlow by Bahal-Dawlah Razi in 15th Century CE.
Authors: Soleymani S, Tajik N, Karimi M, Zargaran A Abstract A herpetic whitlow is a lesion (whitlow) on a finger or thumb caused by herpes simplex virus. It is a painful infection that typically affects the fingers or thumbs. Occasionally infection occurs on the toes or on the nail cuticle. Symptoms of herpetic whitlow include tenderness, swelling and reddening of the infected finger skin, fever and swollen lymph nodes. Although, it is believed that the first recorded observations were in 1909 CE by H. G. Adamson, in the medieval period, Bah?' al-Dawlah N?rbakhsh? Razi (1501 CE) described herpetic whitlow, under t...
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Awake proning in Covid-19 pneumonia.
Authors: Sen MK, Gupta N, Ish P, Kumar R, Yadav SR Abstract Not available. PMID: 32920584 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Stroke as a complication of Coronavirus disease 2019 (COVID-19).
Authors: Marín-Medina DS, Orozco-Hernández JP, Martínez-Muñoz MA, Sánchez-Duque JA Abstract Not available. PMID: 32920585 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Granulocyte colony-stimulating factors (G-CSF) and Covid-19: a double-edged sword?
Authors: Tralongo AC, Danova M Abstract Not available. PMID: 32920586 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Comparison of HIV-DNA decay in naive patients starting dolutegravir plus lamivudine or dolutegravir-based triple therapy.
Authors: Lombardi F, Belmonti S, Borghetti A, Ciccullo A, Fabbiani M, Di Giambenedetto S Abstract Not available. PMID: 32920587 [PubMed - in process] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - September 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Could SARS-CoV-2/COVID-19 simply fade away?
Authors: Rosselli D, Yucumá D, Rodríguez-Morales AJ, Esposito S Abstract not available. PMID: 32532931 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Should lCU COVID-19 patients empirically receive therapeutic doses of anticoagulant?
Authors: Piazza O Abstract not available. PMID: 32532932 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Emerging coronaviruses: first SARS, second MERS and third SARS-CoV-2: epidemiological updates of COVID-19.
Authors: Halaji M, Farahani A, Ranjbar R, Heiat M, Dehkordi FS Abstract Since December 2019, the emergence of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) infection has been reported unexpectedly in Wuhan, China, with staggering infection speed across China and around the world. To date, seven known strains of HCoVs belonging to four genera (i.e., α?, β?, γ, and δ-CoV) have been recognized; the latest one has been identified as the SARS-CoV-2. Although the common transmission routes of SARS-CoV-2 is the respiratory tract, it seems that other routes such as the gastrointestin...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

COVID 19 diagnostic multiplicity and its role in community surveillance and control.
Authors: Tripathi SC, Deshmukh V, Patil A, Tripathy JP Abstract Diagnosis of persons exposed to/infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is central to controlling the global pandemic of COVID-19. Currently, several diagnostic modalities are available for COVID-19, each with its own pros and cons. Although there is a global consensus to increase the testing capacity, it is also essential to prudently utilize these tests to control the pandemic. In this paper, we have reviewed the current array of diagnostics for SARS-CoV-2, highlighted the gaps in current diagnostic modaliti...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Bacterial and fungal infections among patients with SARS-CoV-2 pneumonia.
Authors: Antinori S, Galimberti L, Milazzo L, Ridolfo AL Abstract We reviewed studies reporting bacterial and fungal co-infections in patients with COVID-19. The majority were retrospective studies with poor quality data biased with short follow-up and selection of patients. Septic shock was reported in 4% to 33.1% of patients. Seventy-one to 100% of patients received antibacterial treatments. Invasive pulmonary aspergillosis seems to be an increasingly observed complication in critically ill patients with SARS-CoV-2 infection as previously reported in patients hospitalized in ICU with severe influenza. High qualit...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

COVID-19 and gastrointestinal injury: a brief systematic review and data from Bulgaria.
CONCLUSION: GI may be an important symptom and prognostic factor in COVID-19. Therefore, patients with acute gastrointestinal symptoms must be actively tested for SARS-CoV-2. PMID: 32532936 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Neurologic aspects of covid-19: a concise review.
In conclusion, nervous system symptoms can be observed during SARS-CoV2 infection of which headache and smell and taste disturbance are the main symptoms reported. Cerebrovascular complications can complicate the course of COVID-19 in apparently low-risk patients. GBS is a life-threatening manifestation of COVID-19. PMID: 32532937 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

COVID-19 and pregnancy: a review of current knowledge.
CONCLUSIONS: The clinical findings in pregnant women with COVID-19 are not significantly different compared to other patients, and pregnant women with COVID-19 are not at a higher risk of developing critical pneumonia compared to non-pregnant women. Although, there has been no sign of vertical infection in infants, but maternal infection can cause serious problems such as preterm labour and fetal distress. PMID: 32532938 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Should lCU COVID-19 patients empirically receive therapeutic doses of anticoagulant?
Authors: Di Perri G Abstract In spite of many ongoing attempts to repurpose existing antivirals, no drugs have emerged yet with the desirable activity against SARS-CoV-2. Hydroxychloroquine, lopinavir/ritonavir, remdesivir, umifenovir, favipiravir, ribavirin and beta-interferon-1 gave rise to variable but still inconsistent proof of clinical efficacy in the treatment of COVID-19. Pathogenetic studies have shown significant differences between commonly defined viral pneumonia and COVID-19 pulmonary disease. In severe forms, immune/inflammatory alterations reminiscent of disease forms like Macrophage Activation Syndr...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Comprehensive review of mask utility and challenges during the COVID-19 pandemic.
Authors: Tirupathi R, Bharathidasan K, Palabindala V, Salim SA, Al-Tawfiq JA Abstract Masks are widely discussed during the course of the ongoing COVID-19 pandemic. Most hospitals have implemented universal masking for their healthcare workers, and the Center for Disease Control currently advises even the general public to wear cloth masks when outdoors. The pertinent need for masks arises from plausible dissemination of the SARS-CoV-2 through close contacts, as well as the possibility of virus transmission from asymptomatic, pre-symptomatic, and mildly symptomatic individuals. Given current global shortages in per...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Preparing for emerging respiratory pathogens such as SARS-CoV, MERS-CoV, and SARS-CoV-2.
Authors: Al-Tawfiq JA, Garout MA, Gautret P Abstract Preparing for emerging respiratory pathogens is a fundamental requirement for enhancements of the safeguard in healthcare settings. We are facing an increasing pressure to be prepared more than before. Healthcare organizations should be ready to deal with such emerging infectious disease. Here, we share some points that are essential to be considered while we prepare our institutions to prevent the transmission of emerging respiratory pathogens such as MERS-CoV and the recently emerging pandemic of SARS-CoV-2, the causative agent of COVID-19. PMID: 32532941 [...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

MERS-CoV and SARS-CoV infections in animals: a systematic review and meta-analysis of prevalence studies.
DISCUSSION: A considerable proportion of infected animals tested positive, particularly by nucleic acid amplification tests (NAAT). This essential condition highlights the relevance of individual animals as reservoirs of MERS-CoV and SARS-CoV. In this meta-analysis, camels and bats were found to be positive by RT-PCR in over 10% of the cases for both; thus, suggesting their relevance in the maintenance of wild zoonotic transmission. PMID: 32532942 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Differences among confirmed and not-confirmed COVID-19 patients at "D.Cotugno" hospital, Naples (Italy): what we learned from first suspected cases?
This study contributes to highlight the characteristics to consider at hospital admission in order to promptly suspect COVID-19. PMID: 32532943 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Prognosis of COVID-19: Changes in laboratory parameters.
CONCLUSION: More studies are warranted to further objectively confirm the clinical value of prognostic factors related to SARS-CoV 2 and establish an easy-to-get panel of laboratory findings for evaluating the disease severity. PMID: 32532944 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Risk of hepatic failure in COVID-19 patients. A systematic review and meta-analysis.
Authors: Samidoust P, Samidoust A, Samadani AA, Khoshdoz S Abstract Liver injury has been reported to occur during the disease in severe cases. Therefore, this meta-analysis study aims to investigate the incidence of liver injury among published literature from 2019-Jan-01 to 2020-April-03 to provide an outline for further studies on the liver injury of COVID-19. Four databases including Pubmed, Embase, Web of Science, and the Scopus were searched for studies published from 2019-Jan-01 to 2020-April-03. Data analysis and drawing of charts were performed using the Comprehensive Meta-Analysis Software Version 2.2 (Bi...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

CT features of coronavirus disease 2019 (COVID-19) pneumonia: experience of a single center in Southern Italy.
Authors: Martino A, Fiore E, Mazza EM, Minichiello S, Brogna B, Petronilla S, Megliola A, Musto L Abstract PURPOSE: The aim of this study was to report the radiological features of chest CT scan of patients with coronavirus disease 2019 (COVID-19) living in a town in Southern Italy where a significant outbreak of the disease occurred. METHODS: We revised the CT scan of 62 patients (34 male, 28 female, mean age 71 +/- 14 years) with clinical and laboratory signs of COVID-19, as assessed by positive SARS-CoV-2 RT-PCR testing. All patients underwent chest CT at the time of admission to the hospital. A semi-quantit...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Cognitive load and performance of health care professionals in donning and doffing PPE before and after a simulation-based educational intervention and its implications during the COVID-19 pandemic for biosafety.
DISCUSSION: The PPE donning and doffing is critical and may be changed significantly by active training. In responding to the current COVID-19 pandemic in 2020, activities of training in donning and doffing PPE would provide a means of training personnel, reducing the cognitive load and maybe the risk of contamination and infection of health care workers. PMID: 32532947 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Clinical experience with therapeutic dose of Low-Molecular-Weight Heparin.
Authors: Viale P, Bartoletti M Abstract A 71-year old gentleman with history of arterial hypertension treated with valsartan presented on was hospitalized at the Infectious Diseases Unit, University of Bologna (Italy) for severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2) and received treatment with hydroxychloroquine 200mg bid (400 mg bid the first day), azithromycin 400 mg qd, thrombotic prophylaxis with enoxaparin 4000 UI qd and Venturi mask oxygen delivering FiO2 of 31%. The case highlights the high frequency of coagulopathy in patients with moderate to severe cases of SARS-CoV-2 associated disease (...
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Vitamin C (ovi) D; An unexplored option!
Authors: Ish P, Agrawal S, Gupta N Abstract not available. PMID: 32532949 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Infection prevention and control in blood purification centers during the COVID-19 epidemic: a single institution experience from Zhejiang, China.
Authors: Yamei Y, Yanbo Z, Yuhong J, Xueyan B Abstract not available. PMID: 32532950 [PubMed - as supplied by publisher] (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - June 15, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Clinical aspects of Ebola virus disease: a review.
Authors: Batra S, Ochani RK, Diwan MN, Yasmin F, Qureshi SS, Bhimani S, Shaikh S, Tariq MA, Ahmed Ashraf M, Farooqi HA, Dodani SK Abstract Ebola Virus Disease (EVD), also known as Ebola Hemorrhagic Fever (EHF), initially emerged over 40 years ago in the Democratic Republic of Congo. Endemic to Africa, outbreaks have been recorded in six African countries since its detection in 1976. Fruit bats are believed to be the natural hosts of Ebola viruses (EBoV), with humans and other mammals serving as accidental hosts. Transmission of EBoV has been reported in various ways, including human to human transmission through cl...
Source: Infezioni in Medicina - June 5, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Risk factors for hepatitis B and C among healthy population: a community-based survey from four districts of Southern Italy.
The objective of our community-based study was to assess the prevalence of risk factors and access to the test for viral hepatitis to get information for guiding prevention and screening strategies in our setting. The study was conducted among population of four selected districts in Southern Italy during May 2019. An anonymous structured questionnaire consisting of multiple-choice questions was administered by trained research assistants in order to assess any possible risk factor for HCV or HBV acquisition, and if any screening was previously performed. Six-hundred participants were included: 367 (61.2%) were females, wi...
Source: Infezioni in Medicina - June 5, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Perinatal transmission in Human Immunodeficiency Virus infection: a cross-sectional study from a tertiary care center in North India.
Authors: Kodan P, Gupta N, Ratna S, Ramprasad A, Ranjan S, Nischal N, Soneja M, Wig N Abstract Perinatal transmission of Human Immunodeficiency Virus (HIV) infection is an important mode of transmission in developing countries. The aim of this study was to evaluate the epidemiology of perinatal transmission of HIV infection in pregnant women living with HIV/Acquired Immune Deficiency Syndrome (AIDS). A cross-sectional study was conducted in which HIV positive females who were pregnant at any time between April 2015 and July 2017 were interviewed and their case records analyzed. The collected data were entered and a...
Source: Infezioni in Medicina - June 5, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Knowledge, attitude and practice of medical students towards HIV patients in their pre-clinical and post-clinical years in Karachi, Pakistan: a dual-center cross-sectional study.
Authors: Batra S, Memon ZA, Ochani RK, Awan S, Bhimani S, Siddiqui Y, Mohiuddin A, Farooqi HA Abstract The human immunodeficiency virus (HIV) is currently a global threat with an estimated 38.6 million people affected with HIV worldwide. According to the Joint United Nations Program on HIV/AIDS (UNAIDS), since 2004 the total number of cases of HIV in Pakistan has risen from 2700 to 130,000. In light of the rising burden of HIV/AIDS across the country, it is essential that medical students possess appropriate knowledge regarding the subject. Therefore, we aimed to assess the knowledge, attitude and practice of medic...
Source: Infezioni in Medicina - June 5, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Risk factors for mortality in patients with Coronavirus Disease 2019 (COVID-19) in Bolivia: An analysis of the first 107 confirmed cases.
Authors: Escalera-Antezana JP, Lizon-Ferrufino NF, Maldonado-Alanoca A, Alarcon-De-la-Vega G, Alvarado-Arnez LE, Balderrama-Saavedra MA, Bonilla-Aldana DK, Rodriguez-Morales AJ Abstract The present study is aimed to assess the risk factors for mortality in the first 107 rRT-PCR confirmed cases of SARS-CoV-2 infections in Bolivia. For this observational, retrospective and cross-sectional study, the epidemiological data records were collected from the Hospitals and the Ministry of Health of Bolivia, obtaining the clinical and epidemiological data of the COVID-19 cases that were laboratory-diagnosed during March 2-29,...
Source: Infezioni in Medicina - June 5, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research