Randomized clinical trial to evaluate mometasone lavage vs spray for patients with chronic rhinosinusitis without nasal polyps who have not undergone sinus surgery
ConclusionBoth MFNS and mometasone nasal irrigations are beneficial in symptom management of CRS. Our study suggests that patients who perform mometasone lavage do better in a clinically meaningful way, but our results are not definitive and further studies are warranted. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 29, 2020 Category: Allergy & Immunology Authors: Pawina Jiramongkolchai, Andrew Peterson, Dorina Kallogjeri, Jake J. Lee, Sara Kukuljan, Adam Liebendorfer, John S. Schneider, Cristine N. Klatt ‐Cromwell, Andrew J. Drescher, Jay F. Piccirillo Tags: ORIGINAL ARTICLE Source Type: research

Trans ‐pterygomaxillary fossa sphenoidotomy can result in insufficient exposure for lateral pterygoid recess encephalocele repair
International Forum of Allergy& Rhinology, EarlyView. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 29, 2020 Category: Allergy & Immunology Authors: Sean P. Chislett, Alexander P. Limjuco, Alla Y. Solyar, Donald C. Lanza Tags: LETTER TO THE EDITOR Source Type: research

The use of balloon dilation in revision sinus surgery
ConclusionBSD is used frequently in the revision setting, especially for the frontal sinus and for patients who had already undergone an initial BSD. Our findings highlight the prevalent role of BSD in revision surgery and the need to evaluate such practices. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 29, 2020 Category: Allergy & Immunology Authors: David W. Jang, Derek D. Cyr, Kristine Schulz, Richard Scher, Phil Ryan, Ralph Abi Hachem, David L. Witsell Tags: ORIGINAL ARTICLE Source Type: research

Association between viral infection and increased mucosal eosinophils and CD8+CD103+ T cells in chronic rhinosinusitis
International Forum of Allergy& Rhinology, EarlyView. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 28, 2020 Category: Allergy & Immunology Authors: Rachel K. Goggin, Catherine A. Bennett, Mahnaz Ramezanpour, Hua Hu, Kevin Fenix, Ahmed Bassiouni, Shari Javadiyan, Seweryn Bialasiewicz, Peter ‐John Wormald, Alkis J. Psaltis, Sarah Vreugde Tags: LETTER TO THE EDITOR Source Type: research

Long noncoding RNA MAGI2 ‐AS3/miR‐218‐5p/GDPD5/SEC61A1 axis drives cellular proliferation and migration and confers cisplatin resistance in nasopharyngeal carcinoma
ConclusionMAGI2 ‐AS3/miR‐218‐5p/GDPD5/SEC61A1 axis drove cell proliferation, migration, and epithelial‐mesenchymal transition, and conferred cisplatin resistance in NPC, which may provide a novel insight into the development of NPC. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 25, 2020 Category: Allergy & Immunology Authors: Cheng Cao, Shao Zhou, Jiandao Hu Tags: ORIGINAL ARTICLE Source Type: research

Outcomes of recurrent nasopharyngeal carcinoma patients treated with endoscopic nasopharyngectomy: a meta ‐analysis
ConclusionThe combined OS and DFS rates of rNPC patients treated with endoscopic nasopharyngectomy were summarized and reported in our study. This meta ‐analysis indicated that endoscopic nasopharyngectomy has comparable and possibly better treatment outcomes than intensity‐modulated radiotherapy (IMRT). Therefore, the result of our study indicated that randomized controlled trials (RCTs) are needed in rNPC patients to compare treatment outcome s of endoscopic nasopharyngectomy vs IMRT. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 25, 2020 Category: Allergy & Immunology Authors: Jingyi Yang, Xiaole Song, Xicai Sun, Quan Liu, Li Hu, Hongmeng Yu, Dehui Wang Tags: ORIGINAL ARTICLE Source Type: research

Exhalation delivery system with fluticasone improves quality of life and health status: pooled analysis of phase 3 trials NAVIGATE I and II
BackgroundChronic rhinosinusitis with or without nasal polyps (CRSwNP/CRSsNP) seriously impairs health ‐related quality of life (HRQoL). This analysis describes the impact of the exhalation delivery system with fluticasone (EDS‐FLU) on HRQoL, assessed by the 36‐item Short‐Form Health Survey version 2 (SF‐36v2), and on utilities, assessed via the Short‐Form 6‐Dimension (SF‐6D), in pati ents with CRSwNP.MethodsPost hoc analysis of pooled randomized clinical trial data (NAVIGATE I and II; N = 643) to examine change from baseline in SF ‐36v2 and SF‐6D at end‐of‐double‐blind (EODB: 16 weeks) and end‐...
Source: International Forum of Allergy and Rhinology - May 22, 2020 Category: Allergy & Immunology Authors: Zachary M. Soler, Sam Colman, Fulton F. Velez, Rodney J. Schlosser Tags: ORIGINAL ARTICLE Source Type: research

Predictors of rhinorrhea response after posterior nasal nerve cryoablation for chronic rhinitis
ConclusionIn chronic rhinitis patients, rhinorrhea response to ipratropium was predictive of rhinorrhea improvement after PNN cryoablation. This study has important implications for preoperative counseling and guiding patient expectations when considering PNN cryoablation. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 22, 2020 Category: Allergy & Immunology Authors: Frederick Yoo, Edward C. Kuan, Pete S. Batra, Carmen K. Chan, Bobby A. Tajudeen, John R. Craig Tags: ORIGINAL ARTICLE Source Type: research

Endonasal instrumentation and aerosolization risk in the era of COVID ‐19: simulation, literature review, and proposed mitigation strategies
ConclusionWe confirm that aerosolization presents a risk to the endonasal skull base surgeon. In the outpatient setting, use of a barrier significantly reduces aerosol spread. Cold surgical instrumentation and microdebrider use pose significantly less aerosolization risk than a high ‐speed drill. Procedures requiring drill use should carry a special designation as an “aerosol‐generating surgery” to convey this unique risk, and this supports the need for protective personal protective equipment. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 22, 2020 Category: Allergy & Immunology Authors: Alan D. Workman, D. Bradley Welling, Bob S. Carter, William T. Curry, Eric H. Holbrook, Stacey T. Gray, George A. Scangas, Benjamin S. Bleier Tags: ORIGINAL ARTICLE Source Type: research

Exhalation delivery system with fluticasone improves quality of life and health status: pooled analysis of phase 3 trials NAVIGATE I and II
BackgroundChronic rhinosinusitis with or without nasal polyps (CRSwNP/CRSsNP) seriously impairs health ‐related quality of life (HRQoL). This analysis describes the impact of the exhalation delivery system with fluticasone (EDS‐FLU) on HRQoL, assessed by the 36‐item Short‐Form Health Survey version 2 (SF‐36v2), and on utilities, assessed via the Short‐Form 6‐Dimension (SF‐6D), in pati ents with CRSwNP.MethodsPost hoc analysis of pooled randomized clinical trial data (NAVIGATE I and II; N = 643) to examine change from baseline in SF ‐36v2 and SF‐6D at end‐of‐double‐blind (EODB: 16 weeks) and end‐...
Source: International Forum of Allergy and Rhinology - May 22, 2020 Category: Allergy & Immunology Authors: Zachary M. Soler, Sam Colman, Fulton F. Velez, Rodney J. Schlosser Tags: ORIGINAL ARTICLE Source Type: research

Predictors of rhinorrhea response after posterior nasal nerve cryoablation for chronic rhinitis
ConclusionIn chronic rhinitis patients, rhinorrhea response to ipratropium was predictive of rhinorrhea improvement after PNN cryoablation. This study has important implications for preoperative counseling and guiding patient expectations when considering PNN cryoablation. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 22, 2020 Category: Allergy & Immunology Authors: Frederick Yoo, Edward C. Kuan, Pete S. Batra, Carmen K. Chan, Bobby A. Tajudeen, John R. Craig Tags: ORIGINAL ARTICLE Source Type: research

Patient characteristics of suspected mast ‐cell activation syndrome with sinonasal obstruction: a single institution experience
ConclusionA multidisciplinary approach to the treatment of sinonasal symptoms using both escalation of medical therapy and surgical approaches may improve QOL of patients with suspected MCAS. Consensus criteria for MCAS, which includes elevation in tryptase over baseline during an episode, may exclude the full spectrum of individuals with MCAS from potentially beneficial treatment. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 14, 2020 Category: Allergy & Immunology Authors: Jee ‐Hong Kim, Shijun Xi, Elisabeth H. Ference, Marshall Ge, Mona M. Liu, Bozena B. Wrobel Tags: ORIGINAL ARTICLE Source Type: research

Lynch vs transcaruncular approach: optimizing access to the lateral frontal sinus
ConclusionAdjunctive external approaches can improve access and instrumentation of the frontal sinus when combined with a MELP. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 14, 2020 Category: Allergy & Immunology Authors: Qasim Husain, Catherine Banks, Benjamin S. Bleier Tags: ORIGINAL ARTICLE Source Type: research

Smell and taste alterations in Covid ‐19: a cross‐sectional analysis of different cohorts
Conclusions: OD and GD are more prevalent in home ‐quarantined subjects, and they are independently associated with younger age and female gender.This article is protected by copyright. All rights reserved (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 14, 2020 Category: Allergy & Immunology Authors: Alberto Paderno, Alberto Schreiber, Alberto Grammatica, Elena Raffetti, Michele Tomasoni, Tommaso Gualtieri, Stefano Taboni, Silvia Zorzi, Davide Lombardi, Alberto Deganello, Luca Oscar Redaelli De Zinis, Roberto Maroldi, Davide Mattavelli Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Patient characteristics of suspected mast ‐cell activation syndrome with sinonasal obstruction: a single institution experience
ConclusionA multidisciplinary approach to the treatment of sinonasal symptoms using both escalation of medical therapy and surgical approaches may improve QOL of patients with suspected MCAS. Consensus criteria for MCAS, which includes elevation in tryptase over baseline during an episode, may exclude the full spectrum of individuals with MCAS from potentially beneficial treatment. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 14, 2020 Category: Allergy & Immunology Authors: Jee ‐Hong Kim, Shijun Xi, Elisabeth H. Ference, Marshall Ge, Mona M. Liu, Bozena B. Wrobel Tags: ORIGINAL ARTICLE Source Type: research

Lynch vs transcaruncular approach: optimizing access to the lateral frontal sinus
ConclusionAdjunctive external approaches can improve access and instrumentation of the frontal sinus when combined with a MELP. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 14, 2020 Category: Allergy & Immunology Authors: Qasim Husain, Catherine Banks, Benjamin S. Bleier Tags: ORIGINAL ARTICLE Source Type: research

Smell and taste alterations in Covid ‐19: a cross‐sectional analysis of different cohorts
Conclusions: OD and GD are more prevalent in home ‐quarantined subjects, and they are independently associated with younger age and female gender.This article is protected by copyright. All rights reserved (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 14, 2020 Category: Allergy & Immunology Authors: Alberto Paderno, Alberto Schreiber, Alberto Grammatica, Elena Raffetti, Michele Tomasoni, Tommaso Gualtieri, Stefano Taboni, Silvia Zorzi, Davide Lombardi, Alberto Deganello, Luca Oscar Redaelli De Zinis, Roberto Maroldi, Davide Mattavelli Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

REPLY to “Self‐reported olfactory loss in COVID‐19: is it really a favorable prognostic factor?”
International Forum of Allergy& Rhinology, Accepted Article. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Carol H. Yan, Farhoud Faraji, Adam S. DeConde Tags: LETTER TO THE EDITOR Source Type: research

Self ‐reported olfactory loss in COVID‐19: is it really a favorable prognostic factor?
International Forum of Allergy& Rhinology, Accepted Article. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Claire Hopkins, Luigi Angelo Vaira, Giacomo De Riu Tags: LETTER TO THE EDITOR Source Type: research

Issue Information
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 579-581, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research

Consortium of Otolaryngology Journal Editors: Collegiality and contributions
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 698-699, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Robert T. Sataloff, Rakesh Chandra, Edward W. Fisher, David Goldenberg, Ehab Y. Hanna, Jonas Johnson, David W. Kennedy, Dennis H. Kraus, John H. Krouse, Michael Link, Lawrence R. Lustig, Bert W O'Malley, Jay F. Piccirillo, Robert Ruben, Sand Tags: EDITORIAL Source Type: research

At the center of the COVID ‐19 pandemic: Lessons learned for otolaryngology‐head and neck surgery in China
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 584-586, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Zheng Liu, Luo Zhang Tags: EDITORIAL Source Type: research

Reply (by Kevin Welch) to Zara Patel Correspondence
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 589-590, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Kevin C. Welch Tags: REPLY Source Type: research

COVID ‐19 – Looking beyond the immediate concerns
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 583-583, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Timothy L. Smith Tags: EDITORIAL Source Type: research

Reflections and new developments within the COVID ‐19 pandemic
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 587-588, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Zara M. Patel Tags: CORRESPONDENCE Source Type: research

An inertial sensor ‐based system designed to measure and prevent undesired camera rotation during endoscopic sinus surgery
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 689-691, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Jaime Viera ‐Artiles, José J. Valdiande, Javier Ospina, María Costales, José M. López‐Higuera Tags: LETTER TO THE EDITOR Source Type: research

How aggressive should resection of inverted papilloma be? Refinement of surgical planning based on the 25 ‐year experience of a single tertiary center
ConclusionPreoperative evidence of precancerous changes and/or involvement of maxillary sinus should prompt the surgeon to address the disease more aggressively (centripetal resection). Preoperative imaging and biopsy with abundant material may optimize the chance to stratify patients eligible for less or more conservative approaches. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Marco Ferrari, Alberto Schreiber, Davide Mattavelli, Vittorio Rampinelli, Giacomo Bertazzoni, Michele Tomasoni, Tommaso Gualtieri, Piero Nicolai Tags: ORIGINAL ARTICLE Source Type: research

Topography of polyp recurrence in eosinophilic chronic rhinosinusitis
This study aims to determine, in patients with polyp recurrence, the most common sinuses involved.MethodsA prospective case ‐series was conducted on consecutive adult (≥18 years) post‐FESS eCRS patients followed for a minimum of 12 months. All patients had a neo‐sinus cavity created surgically and used corticosteroid irrigations daily for 3‐6 months, then tapered to disease control. Sinus cavities were assessed by endoscopy on last follow‐up. Polyp recurrence was defined as a score of 5 or 6 in the MLMES in ≥3 sinus cavities. Patient‐reported outcomes based on SNOT22 and NSS, frequency of corticosteroid i...
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Jessica W. Grayson, William Li, Jacqueline Ho, Raquel Alvarado, Janet Rimmer, William A. Sewell, Richard J. Harvey Tags: ORIGINAL ARTICLE Source Type: research

Chronic rhinosinusitis after radiotherapy in patients with head and neck cancer: a population ‐based cohort study in Taiwan
ConclusionThis is the first nationwide population ‐based cohort study to evaluate the risk of posttreatment CRS in patients with head and neck cancer. Our findings indicate that RT is a major risk factor for CRS. Thus, physicians should consider this potential risk in patients with head and neck cancer after RT. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Yen ‐Ting Lu, Ying‐Chou Lu, Hui‐Chen Cheng, Chung‐Han Hsin, Shun‐Fa Yang, Po‐Hui Wang, Huan‐Jui Yeh Tags: ORIGINAL ARTICLE Source Type: research

All ‐trans retinoic acid regulates TGF‐β1‒induced extracellular matrix production via p38, JNK, and NF‐κB‒signaling pathways in nasal polyp‒derived fibroblasts
ConclusionATRA downregulated myofibroblast differentiation, ECM production, cell migration, and collagen gel contraction via p38, JNK ‐dependent NF‐κB‒signaling pathways in TGF‐β1‒induced NPDFs. The findings suggest that ATRA could serve as a novel therapeutic agent to ameliorate nasal polyp development. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Su ‐Jong Kim, Joo‐Hoo Park, Seoung‐Ae Lee, Jong‐Geun Lee, Jae‐Min Shin, Heung‐Man Lee Tags: ORIGINAL ARTICLE Source Type: research

Streamlining care in cystic fibrosis: survey of otolaryngologist, pulmonologist, and patient experiences
The objectives of this study were to: (1) compare otolaryngologists ’ and pulmonlogists’ understanding of long‐term chronic rhinosinusitis (CRS) management; and (2) query patient perceptions of otolaryngologic care and CRS.MethodsA cross ‐sectional survey was administered by the Cystic Fibrosis Foundation in 2018 to patients with CF or their caregivers, otolaryngologists, and pulmonologists. Statistical analysis was performed comparing specialists. Descriptive statistics were computed for patient/caregiver‐reported data.ResultsRespondents included 126 otolaryngologists, 115 pulmonologists, and 186 patient...
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Zainab Farzal, Kelly M. Dean, Satyan B. Sreenath, Sarah E. Hodge, Brian D. Thorp, Charles S. Ebert Jr, Adam M. Zanation, Brent A. Senior, Adam J. Kimple Tags: ORIGINAL ARTICLE Source Type: research

High prevalence of human papillomavirus infection in sinonasal inverted papilloma: a single ‐institution cohort of patients
ConclusionIn a series of 55 IP tissue samples, HPV ‐DNA sequences were identified in 61.8% of cases, which differs from the data of previous investigations. Further case‐control studies are advocated to confirm this prevalence in the Italian population addressed, and also to clarify any pathogenic involvement of HPV in the natural history of IPs . (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Giuliana Frasson, Sonia Cesaro, Diego Cazzador, Giulia Traverso, Enzo Emanuelli, Daniele Borsetto, Giada Munari, Roberta Salmaso, Alessandro Martini, Paolo Boscolo ‐Rizzo, Massimo Rugge Tags: ORIGINAL ARTICLE Source Type: research

A novel device combining acoustic vibration with oscillating expiratory pressure for the treatment of nasal congestion
This study investigated the simultaneous administration of nasal acoustic vibration and oscillating expiratory pressure for the treatment of nasal congestion.MethodsPatients with chronic nasal congestion but without fixed anatomic obstruction participated in a prospective clinical study applying simultaneous acoustic vibrations and positive expiratory pressure to the nasal cavity twice daily over 5 weeks. Safety was assessed by rhinoscopy and patient questionnaires. Efficacy was assessed using peak nasal inspiratory flow (PNIF), visual analogue scale (VAS) of nasal symptoms, Total Nasal Symptom Score (TNSS), Nasal Obstruct...
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Zachary M. Soler, Shaun A. Nguyen, Craig Salvador, Thomas Lackland, Vincent M. Desiato, Kristina Storck, Rodney J. Schlosser Tags: ORIGINAL ARTICLE Source Type: research

Impact of induction chemotherapy and socioeconomics on sinonasal undifferentiated carcinoma survival
BackgroundSinonasal undifferentiated carcinoma (SNUC) is an uncommon malignancy of the nasal cavity and accessory sinuses with limited available studies evaluating role of induction chemotherapy (IC), demographics, and socioeconomic factors on overall survival (OS).MethodsThe 2004 ‐2015 National Cancer Database was queried for patients with histologically confirmed SNUC. IC was defined as chemotherapy administered 6 months to 2 weeks before surgery or ≥45 days before radiotherapy.ResultsOf 440 identified patients, 70 (16%) underwent treatments involving IC. This consisted of 52 (12%), 15 (3%), and 3 (1%) patients rece...
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Brandon M. Lehrich, Khodayar Goshtasbi, Arash Abiri, Tyler Yasaka, Ronald Sahyouni, Peter Papagiannopoulos, Bobby A. Tajudeen, Edward C. Kuan Tags: ORIGINAL ARTICLE Source Type: research

Lateral nasal wall flap for endoscopic reconstruction of the skull base: anatomical study and clinical series
ConclusionBlood supply to the nasal floor by the dominant inferior meatus branch is more robust than the supply to the anterior LNW by the superficial arterial branch. The LNW flap is the preferred vascularized reconstructive option to the PCF and sella in the absence of a nasoseptal flap (NSF). (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Philippe Lavigne, Maria Belen Vega, Omar H. Ahmed, Paul A. Gardner, Carl H. Snyderman, Eric W. Wang Tags: ORIGINAL ARTICLE Source Type: research

Concordance of self ‐reported practice patterns of American Rhinologic Society members with the International Consensus Statement of Allergy and Rhinology: Rhinosinusitis
ConclusionThe range of reported treatment patterns identified in this study despite the availability of the ICAR:RS recommendations may suggest the need for improved standardization of CRS management. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Charles A. Riley, Zhong Zheng, Nicholas Williams, Timothy L. Smith, Richard R. Orlandi, Abtin Tabaee Tags: ORIGINAL ARTICLE Source Type: research

Quality ‐of‐life and olfaction changes observed with short‐term medical management of chronic rhinosinusitis
BackgroundPatients with chronic rhinosinusitis (CRS) commonly experience both reduced quality of life (QOL) and olfactory dysfunction (OD). Literature on the impacts of appropriate medical therapy (AMT) for CRS on QOL and OD is limited, and the focused design of these studies may limit their applicability to usual clinical practice.MethodsAdults with symptomatic CRS were prospectively enrolled (November 2016 to October 2018) into an observational, multi ‐institutional study. Individualized AMT was initiated using standard practice according to evidence‐based guidelines. Endoscopy examination (Lund‐Kennedy), olfactory...
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Andrew J. Thomas, Jess C. Mace, Vijay R. Ramakrishnan, Jeremiah A. Alt, Jose L. Mattos, Rodney J. Schlosser, Zachary M. Soler, Timothy L. Smith Tags: ORIGINAL ARTICLE Source Type: research

Expression of nicotinamide adenine dinucleotide phosphate oxidase in chronic rhinosinusitis with nasal polyps
ConclusionThe levels of p67phox messenger RNA (mRNA) and protein as well as 4 ‐HNE were both upregulated in NP tissue, suggesting that p67phox and oxidative stress play roles in the pathogenesis of CRSwNP. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Kaili Zheng, Jin Hao, Lei Xiao, Min Wang, Yan Zhao, Dachuan Fan, Ying Li, Xiangdong Wang, Luo Zhang Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 579-581, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research

Consortium of Otolaryngology Journal Editors: Collegiality and contributions
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 698-699, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Robert T. Sataloff, Rakesh Chandra, Edward W. Fisher, David Goldenberg, Ehab Y. Hanna, Jonas Johnson, David W. Kennedy, Dennis H. Kraus, John H. Krouse, Michael Link, Lawrence R. Lustig, Bert W O'Malley, Jay F. Piccirillo, Robert Ruben, Sand Tags: EDITORIAL Source Type: research

Reflections and new developments within the COVID ‐19 pandemic
International Forum of Allergy& Rhinology, Volume 10, Issue 5, Page 587-588, May 2020. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Zara M. Patel Tags: CORRESPONDENCE Source Type: research

REPLY to “Self‐reported olfactory loss in COVID‐19: is it really a favorable prognostic factor?”
International Forum of Allergy& Rhinology, Accepted Article. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Carol H. Yan, Farhoud Faraji, Adam S. DeConde Tags: LETTER TO THE EDITOR Source Type: research

Self ‐reported olfactory loss in COVID‐19: is it really a favorable prognostic factor?
International Forum of Allergy& Rhinology, Accepted Article. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 12, 2020 Category: Allergy & Immunology Authors: Claire Hopkins, Luigi Angelo Vaira, Giacomo De Riu Tags: LETTER TO THE EDITOR Source Type: research

Investigation of topical intranasal cocaine for sinonasal procedures: a randomized, phase III clinical trial
ConclusionTopical 4% and 8% cocaine is an effective anesthetic that can be safely administered for nasal procedures. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 8, 2020 Category: Allergy & Immunology Authors: John McGrath, Alexa McGrath, Jacob Burdett, Tom Shokri, Jason E. Cohn Tags: ORIGINAL ARTICLE Source Type: research

Smell and taste symptom ‐based predictive model for COVID‐19 diagnosis
BackgroundThe presentation of COVID ‐19 overlaps with common influenza symptoms. There is limited data on whether a specific symptom or collection of symptoms may be useful to predict test positivity.MethodsAn anonymous electronic survey was publicized through social media to query participants with COVID ‐19 testing. Respondents were questioned regarding 10 presenting symptoms, demographic information, comorbidities and COVID‐19 test results. Stepwise logistic regression was used to identify predictors for COVID positivity. Selected classifiers were assessed for prediction performance using rece iver operating chara...
Source: International Forum of Allergy and Rhinology - May 4, 2020 Category: Allergy & Immunology Authors: Lauren T. Roland, Jose G. Gurrola, Patricia A. Loftus, Steven W. Cheung, Jolie L. Chang Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Application of holographic augmented reality for external approaches to the frontal sinus
ConclusionWe describe proof of concept of a novel technique utilizing AR to enhance external approaches to the frontal sinus. Holographic AR ‐enhanced surgical navigation holds promise for enhanced visualization of target structures during surgical approaches to the sinuses. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 3, 2020 Category: Allergy & Immunology Authors: Caio A. Neves, Yona Vaisbuch, Christoph Leuze, Jennifer A. McNab, Bruce Daniel, Nikolas H. Blevins, Peter H. Hwang Tags: ORIGINAL ARTICLE Source Type: research

Predicting prolonged length of stay after endoscopic transsphenoidal surgery for pituitary adenoma
BackgroundEndoscopic transsphenoidal surgery (ETS) for the resection of pituitary adenoma has become more common throughout the past decade. Although most patients have a short postoperative hospitalization, others require a more prolonged stay. We aimed to identify predictors for prolonged hospitalization in the setting of ETS for pituitary adenomas.MethodsA retrospective chart review as performed on 658 patients undergoing ETS for pituitary adenoma at a single tertiary care academic center from 2005 to 2019. Length of stay (LoS) was defined as date of surgery to date of discharge. Patients with LoS in the top 10th percen...
Source: International Forum of Allergy and Rhinology - May 3, 2020 Category: Allergy & Immunology Authors: Swar Vimawala, Chandala Chitguppi, Erin Reilly, Judd H. Fastenberg, Tomas Garzon ‐Muvdi, Christopher Farrell, Mindy R. Rabinowitz, Marc R. Rosen, James Evans, Gurston G. Nyquist Tags: ORIGINAL ARTICLE Source Type: research

A case for multidisciplinary management of chronic rhinosinusitis with nasal polyposis
International Forum of Allergy& Rhinology, EarlyView. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 3, 2020 Category: Allergy & Immunology Authors: Devyani Lal, Larry Borish, Kara Y. Detwiller, Stacey T. Gray, Shyam Joshi, Robert C. Kern, Tanya M. Laidlaw, Michael J. Marino, Spencer C. Payne, Anju T. Peters, Zachary M. Soler, Matthew A. Rank Tags: EDITORIAL Source Type: research