COVID-19 booster vaccination and dialysis patients
If you do not work in renal medicine you may not have realized that dialysis patients given the COVID-19 vaccine, demonstrate significantly lower antibody response compared to healthy controls. National strategies for Booster COVID-19 vaccines range from targeting vulnerable patient populations, to broadening out to healthcare workers or as in Israel, targeting the whole adult population. We welcome the Commentary piece by Dr Yen and colleagues from Chang Gung University in Taiwan who highlight the importance of dialysis patients receiving the booster vaccine. They summarize our current knowledge and draw our attention to ...
Source: QJM - November 5, 2021 Category: Internal Medicine Source Type: research

Corrigendum
In the originally published versions of the below listed manuscripts, author O M P Jolobe ’s corresponding address should read: “Oscar M P Jolobe MRCP(UK), Flat 6 Souchay Court, 1 Clothorn Road. Manchester, M20 6BR” instead of “From the Medical Division, Manchester Medical Society, Simon Building, Brunswick Street, Manchester M13 9PL”. (Source: QJM)
Source: QJM - November 5, 2021 Category: Internal Medicine Source Type: research

Would Louis Pasteur be accepted for medical school entry today?
As a consequence of increasing pressures on our medical schools —has our entry selection processes become more rigid and formulaic with the significant risk that we fail to reward the lateral thinkers and those with an innovatory spirit? (Source: QJM)
Source: QJM - October 4, 2021 Category: Internal Medicine Source Type: research

Comparative Study between the Effect of Ultrasound Guided Pectoral Nerve Block (PEC 1) versus Serratus Anterior Plane Block (SAPB) For Postoperative Analgesia in Modified Radical Mastectomy
ConclusionSAPB was effective in reducing postoperative pain scores for 6 -12  hours and lower total 24-h postoperative opioid and analgesic consumption after Modified Radical Mastectomy under general anesthesia, compared to PEC 1 block. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Comparison between Nalbuphine and Ketamine as an adjuvant to Heavy Bupivacaine on Post Dural Puncture Headache
ConclusionAdding nalbuphine, and not ketamine, with hyperbaric bupivacaine in spinal anesthesia decreased incidence of post dural puncture headache, and prolonged the duration of sensory block. Both groups provided adequate anesthesia and analgesia with good hemodynamic stability. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

A Comparative Study between Intrathecal Fentanyl and Dexmedetomidine as Adjuvants to Hyperbaric Levobupivacaine 0.5% in Patients Undergoing Infra Umbilical Surgeries
ConclusionFrom the current study we can conclude that using intrathecal 5 µg dexmedetomidine seems to be a suitable alternative to 25 µg fentanyl as adjuvants to 0.5% hyperbaric levobupivacaine in spinal anaesthesia. Its associated with prolonged motor and sensory block and provides good quality of intraoperative analgesia and extended duration of post operative analges ia as compared to fentanyl. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Effects of Delayed Supine Positioning after Induction of Subarachnoid Block on Post-spinal Hemodynamic Changes Compared to Traditional Subarachnoid Block: prospective observational randomized controlled dose response clinical study
ConclusionUnder the conditions of this study delayed supine positioning after induction of SAB for 2.5  minutes is of great value in gaining an adequate level of anesthesia with more hemodynamic stability and less vasopressor need as a management of hypotension compared to the conventional SAB in Knee Arthroscope surgery. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Post Stroke Hyperglycemia as a marker of Stroke Severity and Prognosis: A cohort study
ConclusionFrom our study we can conclude that diabetes mellitus as a risk factor in cases of stroke leads to increase complications and worsens the outcome in cases of stroke whether hemorrhagic or ischemic.RecommendationsFrom our study we recommended strict control of diabetes mellitus when present in cases of stroke to avoid bad outcome and to prevent complications in these cases. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Evaluation of the effect of diastolic function on prognosis of patient with septic shock
ConclusionWe recommend assessment of patients admitted to the ICU with septic shock via echocardiography to determine the grade of diastolic dysfunction and using diastolic dysfunction as a predictive risk factor in various score assessment of ICU patients. Our study was limited by decreased sample size and we recommend further studies with increased sample size.. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Hypophosphatemia and weaning of Mechanically Ventilated patients with Chronic Obstructive Pulmonary Disease during acute exacerbations
ConclusionIn the light of the previous results Hypophosphatemia (1.5 - 2.5  mg/dL) was associated with poor prognosis in terms of longer durations of mechanical ventilations and higher ICU mortality rates in mechanically ventilated patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD), Hypophosphatemia should be included in initial assessmen t of such patients to stratify them. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Pleural Ultrasonography versus Chest Radiography for the Diagnosis of Pneumothorax
ConclusionsIn conclusion, US represent a good approach for the evaluation of PTX, with advantages of timeliness, high accuracy and high reliability. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Effect of Usage of the Proton Pump Inhibitor Omeprazole on the Structure of the Kidney of Male Albino Rats
ConclusionThe present study declared that long term use of omeprazole resulted in structural damage of rat renal tissue with associated deterioration of renal function in a time dependent manner.Extreme caution should be taken with clinical prescription of omeprazole and close monitoring of renal function is highly recommended. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Incidence and Association of Patient Safety Indicator 9 (Perioperative hemorrhage or hematoma) and clinical outcomes in Cardio-thoracic surgery hospital, Ain Shams University, Egypt
Conclusionhigh incidence rate of PSI9 and the incidence is higher in male gender and 60 years old and more patients. Those patients developed PSI9 were at high risk for readmission and death.Recommendationsthe hospital administration should consider strategies and policies to decrease the rate of PSI9 and subsequent unfavorable clinical outcomes. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Effect of Weight Loss Program on Anthropometric and Laboratory Measurements among Adult Obese Females: An Intervention Study
Conclusion and Recommendation: Prevention of obesity should be a high priority in public health, with particular emphasis on encouraging healthy lifestyles in all age groups, starting from early childhood. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Participation and Satisfaction with the National Campaign on Viral Hepatitis C and Non-Communicable Diseases among Administrative Workers of Ain Shams University, Cairo, Egypt
ConclusionsMost of the study group participated in the initiative 100 Million Seha and were satisfied with the service provided. Mass media played the most important role in awareness with the campaign. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research