Exposure to Toxocara spp. and Ascaris lumbricoides infections and risk of allergic rhinitis in children
Substantial experimental studies suggest a role for helminthes infections in the pathogenesis of allergies, but epidemiologic data have been inconsistent. Unlike to asthma, the association between helminthes i... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 30, 2020 Category: Allergy & Immunology Authors: Iraj Mohammadzadeh, Sorena Darvish, Seyed Mohammad Riahi, Solmaz Alizadeh Moghaddam, Mohammad Pournasrollah, Mousa Mohammadnia-Afrozi and Ali Rostami Tags: Research Source Type: research

Skin testing with bendamustine: what concentration should be used?
We present a case of the patient, who developed hypersensitivity reaction during the treatment of chronic lymphocytic leukemia. Bendamustine was suspected as a culprit agent. The patient as well as 3 controls ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 30, 2020 Category: Allergy & Immunology Authors: Laura Malinauskiene, Kestutis Cerniauskas, Kotryna Linauskiene, Linas Griguola, Anzelika Chomiciene and Audra Blaziene Tags: Letter to the editor Source Type: research

The effect of electronic monitoring combined with weekly feedback and reminders on adherence to inhaled corticosteroids in infants and younger children with asthma: a randomized controlled trial
Adherence to asthma treatment among children is usually poor. We sought to explore whether electronic adherence monitoring combined with weekly feedback regarding adherence along with a reminder to use inhaled... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 29, 2020 Category: Allergy & Immunology Authors: Jiande Chen, Juan Xu, Liebin Zhao, Jing Zhang, Yong Yin and Fen Zhang Tags: Research Source Type: research

Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants
Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with a new microbiome profile established in Chinese i... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 25, 2020 Category: Allergy & Immunology Authors: Jing Guo, Xiaoping Zhang, Aarti Saiganesh, Christopher Peacock, Shu Chen, Gary A. Dykes, Belinda J. Hales, Peter N. Le Sou ëf and Guicheng Zhang Tags: Research Source Type: research

The clinical, immunological and genetic features of 12 Chinese patients with STAT3 mutations
Loss-of-function (LOF) mutations in signal transducer and activator of transcription 3 (STAT3) is one of the causes of STAT3 hyperimmunoglobulin E (IgE) syndrome (STAT3-HIES), while gain-of-function (GOF) muta... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 22, 2020 Category: Allergy & Immunology Authors: Li Lin, Ying Wang, Bijun Sun, Luyao Liu, Wenjing Ying, Wenjie Wang, Qinhua Zhou, Jia Hou, Haili Yao, Liyuan Hu, Jinqiao Sun and Xiaochuan Wang Tags: Research Source Type: research

Differences in serum markers of oxidative stress in well controlled and poorly controlled asthma in Sri Lankan children: a pilot study
Asthma is a disease characterised by hyper responsiveness and bronchoconstriction of airways, and is a major health burden globally. A dysfunction of the oxidant-antioxidant balance, termed oxidative stress, h... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 22, 2020 Category: Allergy & Immunology Authors: Yenuli Fernando, Pujitha Wickramasinghe, Udani De Silva, Malintha Alahakoon, K. W. D. A. Anuradha and Shiroma Handunnetti Tags: Research Source Type: research

Change in exhaled nitric oxide during peanut challenge is related to severity of reaction
Peanut allergy affects 3% of Australian children and has a higher risk of anaphylaxis than most food allergies. Predicting who is likely to develop anaphylaxis is still an inexact science. The fraction of exha... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 21, 2020 Category: Allergy & Immunology Authors: Elizabeth Percival, Rani Bhatia, Kahn Preece, Mark McEvoy, Adam Collison and Joerg Mattes Tags: Research Source Type: research

Natural history, prognostic factors and patient perceived response to treatment in chronic spontaneous urticaria
Although the diagnosis and management of chronic spontaneous urticaria (CSU) is well documented in the literature, some aspects of the disease remain unclear. We aimed to further describe the natural history, ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 15, 2020 Category: Allergy & Immunology Authors: Peter Stepaniuk, Manstein Kan and Amin Kanani Tags: Research Source Type: research

Genetic polymorphisms in vitamin D pathway influence 25(OH)D levels and are associated with atopy and asthma
Vitamin D deficiency or insufficiency, has been associated with atopy and lack of asthma control. Our objective was to investigate associations between variants in genes of vitamin D pathway with serum levels ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 9, 2020 Category: Allergy & Immunology Authors: Alana Alc ântara Galvão, Flávia de Araújo Sena, Emília Maria Medeiros de Andrade Belitardo, Maria Borges Rabelo de Santana, Gustavo Nunes de Oliveira Costa, Álvaro Augusto Cruz, Maurício Lima Barreto, Ryan dos Santos Costa, Neuza Maria Alcantara-Ne Tags: Research Source Type: research

Th17/Treg imbalance is associated with reduced indoleamine 2,3 dioxygenase activity in childhood allergic asthma
The differentiation of CD4+  lymphocytes Th17/regulatory T cells (Treg) and indoleamine 2,3-dioxygenase (IDO) is associated with the pathogenesis of allergic asthma. Basic research has shown that IDO is likely ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 7, 2020 Category: Allergy & Immunology Authors: Ying Hu, Zhiqiang Chen, Jing Zeng, Shouyan Zheng, Liujuan Sun, Li Zhu and Wei Liao Tags: Research Source Type: research

Facial erythema after the treatment of dupilumab in SLE patient
Dupilumab is a receptor antagonist binding to the alpha subunit of the interleukin-4 receptor. Through binding to it, dupilumab inhibits signaling of both IL-4 and IL-13, the representative Th2 biomarkers. Rec... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 3, 2020 Category: Allergy & Immunology Authors: Dong Hyek Jang, Jae In Lee, Joo Yoon Bae, Hye Jung Jung, Mi Yeon Park and Jiyoung Ahn Tags: Case report Source Type: research

Inhalation of nebulized Mycobacterium vaccae can protect against allergic bronchial asthma in mice by regulating the TGF- β/Smad signal transduction pathway
Mycobacterium vaccae nebulization imparted protective effect against allergic asthma in a mouse model. The TGF- β/Smad signal transduction pathway plays an important role in allergic bronchial asthma. However, the... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 2, 2020 Category: Allergy & Immunology Authors: Xiao-hong Jiang, Chao-qian Li, Guang-yi Feng, Ming-jie Luo and Qi-xiang Sun Tags: Research Source Type: research

Sensitivity and specificity of double-blinded penicillin skin testing in relation to oral provocation with amoxicillin in children
Current recommendations for the management of penicillin allergy are to perform penicillin skin testing (PST) with penicilloyl-polylysine (PPL) and benzylpenicillin (BP) prior to drug challenge with amoxicilli... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 1, 2020 Category: Allergy & Immunology Authors: Roxane Labrosse, Louis Paradis, Kathryn Samaan, Jonathan Lacombe-Barrios, Jean Paradis, Philippe B égin and Anne Des Roches Tags: Letter to the editor Source Type: research

Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s
The prevalence of allergic rhinitis (AR), an environment- and lifestyle-dependent condition, has been constantly increasing in Korea. Although the environment and lifestyle of the Korean people have recently u... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - July 1, 2020 Category: Allergy & Immunology Authors: Ji Heui Kim, Shin Ae Kim, Ja Yoon Ku, Won Ki Cho and Chol Ho Shin Tags: Research Source Type: research

Type I allergic reaction to rituximab upon first lifetime exposure: a case report
While drug reactions to rituximab have been commonly reported in the literature, a type I allergic reaction to rituximab after first lifetime exposure has never been reported. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 26, 2020 Category: Allergy & Immunology Authors: V. Polito, A. Barbacki and G. Isabwe Tags: Case report Source Type: research

An emerging allergen: Cannabis sativa allergy in a climate of recent legalization
Considering its recent legalization in Canada, the health implications of Cannabis sativa exposure, including allergy, are coming to the forefront of medical study and interest. C. sativa allergy is an issue that... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 26, 2020 Category: Allergy & Immunology Authors: Bradley Jackson, Erica Cleto and Samira Jeimy Tags: Short report Source Type: research

Incidence of malignancy in patients with common variable immunodeficiency according to therapeutic delay: an Italian retrospective, monocentric cohort study
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency and has a broad spectrum of clinical manifestations. Among non-infectious complications, an increased incidence o... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 26, 2020 Category: Allergy & Immunology Authors: Veronica Pedini, Jacopo Umberto Verga, Irene Terrenato, Denise Menghini, Cristina Mezzanotte and Maria Giovanna Danieli Tags: Research Source Type: research

Differential response to biologics in a patient with severe asthma and ABPA: a role for dupilumab?
Allergic bronchopulmonary aspergillosis (ABPA) is a severe hypersensitivity reaction to aspergillus species colonizing the airways of patients with asthma or cystic fibrosis. Biologics including anti-IgE and a... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 26, 2020 Category: Allergy & Immunology Authors: Carlo M ümmler, Bernd Kemmerich, Jürgen Behr, Nikolaus Kneidinger and Katrin Milger Tags: Case report Source Type: research

Proceedings of the Canadian Society of Allergy and Clinical Immunology Annual Scientific Meeting 2019
(Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 24, 2020 Category: Allergy & Immunology Tags: Meeting abstracts Source Type: research

Asthma increases the risk of herpes zoster: a nested case –control study using a national sample cohort
This study aimed to complement previous studies on the risk of herpes zoster in the asthmatic adult population. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 23, 2020 Category: Allergy & Immunology Authors: So Young Kim, Dong Jun Oh and Hyo Geun Choi Tags: Research Source Type: research

Anaphylaxis to clindamycin following cutaneous exposure
The role and importance of skin barrier as an immunologic organ and as a potent way of sensitization is well known. However, antibiotics anaphylaxis following skin sensitization has not been reported. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 19, 2020 Category: Allergy & Immunology Authors: N. Paradis, L. Marois, L. Paradis, F. Graham, P. B égin and A. Des Roches Tags: Case report Source Type: research

Efficacy of omalizumab in children, adolescents, and adults with severe allergic asthma: a systematic review, meta-analysis, and call for new trials using current guidelines for assessment of severe asthma
Omalizumab is approved for treating severe allergic asthma from age 6, but the definition of severe asthma including a systematic assessment to rule out difficult-to-treat asthma has changed since the drug was... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 18, 2020 Category: Allergy & Immunology Authors: Daniel P. Henriksen, Uffe Bodtger, Kirsten Sidenius, Niels Maltbaek, Lars Pedersen, Hanne Madsen, Ehm A. Andersson, Ole Norgaard, Louise K. Madsen and Bo L. Chawes Tags: Review Source Type: research

Serum BPI as a novel biomarker in asthma
Neutrophils, eosinophils and inflammatory cells contribute to asthmatic inflammation. The anti-bactericidal/permeability-increasing protein (BPI), produced by neutrophils, peripheral blood monocytes or epithel... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 18, 2020 Category: Allergy & Immunology Authors: Chen Xingyuan and Qiu Chen Tags: Research Source Type: research

A rare case of anaphylaxis to Indian jujube (Ziziphus Mauritiana Lam)
Indian jujube (Ziziphus Mauritiana Lam) is a sweet fruit from a tree native to tropical and subtropical regions of Asia and India. A few case reports have implicated Indian jujube to cause latex-fruit syndrome. W... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 17, 2020 Category: Allergy & Immunology Authors: Babak Aberumand and Rozita Borici-Mazi Tags: Case report Source Type: research

Anaphylaxis to three humanized antibodies for severe asthma: a case study
Omalizumab, mepolizumab, benralizumab, and dupilumab are the currently available biologics used to treat asthma in Japan. Anaphylaxis following treatment with mepolizumab or benralizumab is considered rare. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 10, 2020 Category: Allergy & Immunology Authors: Koichi Jingo, Norihiro Harada, Toshihiko Nishioki, Masahiro Torasawa, Tomoko Yamada, Tetsuhiko Asao, Haruhi Takagi, Tomohito Takeshige, Jun Ito and Kazuhisa Takahashi Tags: Case report Source Type: research

Effects of MP-AzeFlu enhanced by activation of bitter taste receptor TAS2R
MP-AzeFlu is relatively new a pharmaceutical drug used in the treatment of allergic rhinitis. It is comprised of azelastine hydrochloride (AZE), a potent histamine-H1-receptor antagonist and fluticasone propio... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - June 3, 2020 Category: Allergy & Immunology Authors: Sandra Ekstedt, Susanna Kumlien Geor én and Lars Olaf Cardell Tags: Letter to the editor Source Type: research

Tonsillar granuloma associated with hypogammaglobulinemia
Rare tonsillar granulomas may be caused for example by infections, malignancies or sarcoidosis. Granulomas also occur in inborn errors of immunity (IEI) such as common variable immunodeficiency (CVID) with B c... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 29, 2020 Category: Allergy & Immunology Authors: Aleksi Laajala, Outi Kuismin, Mikko Tastula, Leena Tiitto, Saila Kauppila, Anna Salo, Pirjo Åström, Antti Nissinen, Virpi Glumoff, Mikko R. J. Seppänen and Timo Hautala Tags: Case report Source Type: research

Season of birth is associated with increased risk of atopic dermatitis in Japanese infants: a retrospective cohort study
Several epidemiological studies have examined the possibility of a relationship between season of birth and atopic dermatitis (AD) and food allergy (FA), yet their results are contradictory. We investigated th... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 29, 2020 Category: Allergy & Immunology Authors: Yu Kuwabara, Ritsue Nii, Keiko Tanaka, Eiichi Ishii, Mizuho Nagao and Takao Fujisawa Tags: Research Source Type: research

Towards definitive management of allergic rhinitis: best use of new and established therapies
Allergic rhinitis (AR) is an inflammatory disease of the nasal mucosa impacting up to 25% of Canadians. The standard of care for AR includes a treatment plan that takes into account patient preferences, the se... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 27, 2020 Category: Allergy & Immunology Authors: Lubnaa Hossenbaccus, Sophia Linton, Sarah Garvey and Anne K. Ellis Tags: Review Source Type: research

Epidermal growth factor upregulates expression of MUC5AC via TMEM16A, in chronic rhinosinusitis with nasal polyps
Mucus hypersecretion and goblet cell upregulation are common features of chronic rhinosinusitis with nasal polyps (CRSwNP). Although epidermal growth factor (EGF) has been reported to stimulate the expression ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 27, 2020 Category: Allergy & Immunology Authors: Jian Jiao, Tao Zhang, Yu Zhang, Jingyun Li, Min Wang, Ming Wang, Ying Li, Xiangdong Wang and Luo Zhang Tags: Research Source Type: research

Co-occurrence between C1 esterase inhibitor deficiency and autoimmune disease: a systematic literature review
Hereditary angioedema (HAE) is caused by a SERPING1 gene defect resulting in decreased (Type I) or dysfunctional (Type II) C1 esterase inhibitor (C1-INH). The prevalence of autoimmune diseases (ADs) in patient... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 27, 2020 Category: Allergy & Immunology Authors: Donald Levy, Timothy Craig, Paul K. Keith, Girishanthy Krishnarajah, Rachel Beckerman and Subhransu Prusty Tags: Research Source Type: research

Hereditary angioedema C1-esterase inhibitor replacement therapy and coexisting autoimmune disorders: findings from a claims database
In this letter to the editor, we present results of claims data analysis. This claims data analysis supports a hypothesis that in patients with hereditary angioedema due to C1-esterase inhibitor (C1-INH) defic... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 27, 2020 Category: Allergy & Immunology Authors: Henriette Farkas, Donald Levy, Dylan Supina, Melvin Berger, Subhransu Prusty and Moshe Fridman Tags: Letter to the editor Source Type: research

Assessment of clinical activity and severity using serum ANCA and ASCA antibodies in patients with ulcerative colitis
Ulcerative colitis (UC) is a chronic, non-specific inflammatory bowel disease (IBD) with unknown etiology. The lack of specific clinical manifestations, standard diagnostic criteria, objective and accurate ind... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 20, 2020 Category: Allergy & Immunology Authors: Yanhua Pang, Huijie Ruan, Dongfang Wu, Yanfei Lang, Ke Sun and Cuiping Xu Tags: Research Source Type: research

Correction to: Protocol for a double-blind, randomized controlled trial on the dose-related efficacy of omalizumab in multi-food oral immunotherapy
An amendment to this paper has been published and can be accessed via the original article. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 20, 2020 Category: Allergy & Immunology Authors: Alexandra Langlois, Marie-H élène Lavergne, Hélène Leroux, Kerstin Killer, Pauline Azzano, Louis Paradis, Kathryn Samaan, Jonathan Lacombe-Barrios, Thomas Eiwegger, Julia Upton, Gordon Sussman, Thomas Poder, Benoît Mâsse, Anne Des Roches and Philipp Tags: Correction Source Type: research

Quercetin with the potential effect on allergic diseases
Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Querceti... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 14, 2020 Category: Allergy & Immunology Authors: Morteza Jafarinia, Mahnaz Sadat Hosseini, Neda kasiri, Niloofar Fazel, Farshid Fathi, Mazdak Ganjalikhani Hakemi and Nahid Eskandari Tags: Review Source Type: research

Delivery of subcutaneous immunoglobulin by rapid “push” infusion for primary immunodeficiency patients in Manitoba: a retrospective review
Both intravenous and subcutaneous human immune globin G (IgG) replacement (IVIG and SCIG, respectively) reduce severe infection and increase serum IgG levels in primary immune deficiency disorder (PIDD) patien... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 13, 2020 Category: Allergy & Immunology Authors: Graham Walter, Chrystyna Kalicinsky, Richard Warrington, Marianne Miguel, Jeannette Reyes and Tamar S. Rubin Tags: Research Source Type: research

Increasing allergy: are antibiotics the elephant in the room?
Antibiotics cause dramatic changes to the human microbiome. The composition of the microbiome has been associated with changes in the immune system and these changes are beginning to be linked to immune diseas... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 13, 2020 Category: Allergy & Immunology Authors: Rod A. Herman Tags: Letter to the editor Source Type: research

Correction to: The International/Canadian Hereditary Angioedema Guideline
An amendment to this paper has been published and can be accessed via the original article. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - May 6, 2020 Category: Allergy & Immunology Authors: Stephen Betschel, Jacquie Badiou, Karen Binkley, Rozita Borici-Mazi, Jacques H ébert, Amin Kanani, Paul Keith, Gina Lacuesta, Susan Waserman, Bill Yang, Emel Aygören-Pürsün, Jonathan Bernstein, Konrad Bork, Teresa Caballero, Marco Cicardi, Timothy Cra Tags: Correction Source Type: research

Lemon seed allergy: a case presentation
We report a case of IgE-mediated hypersensitivity to lemon seed. We demonstrate for the first time a pattern of cross-sensitisation between seeds of citrus hybrid species from similar ancestral species origins. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 29, 2020 Category: Allergy & Immunology Authors: O. Stephanie Kayode, Nuevalynne Prado, David J. Thursfield, Stephen J. Till and Leonard Q. C. Siew Tags: Case report Source Type: research

A preseason booster prolongs the increase of allergen specific IgG4 levels, after basic allergen intralymphatic immunotherapy, against grass pollen seasonal allergy
Allergen specific IgG4 levels have been monitored as a surrogate marker for the tolerance inducing effect of subcutaneous immunotherapy (SCIT) in many studies. Its accuracy at group level has been well establi... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 28, 2020 Category: Allergy & Immunology Authors: Dan Weinfeld, Ulla Westin, Laila Hellkvist, Ulf-Henrik Mellqvist, Ingvar Jacobsson and Lars-Olaf Cardell Tags: Research Source Type: research

Local eosinophils are associated with increased IgA subclass levels in the sinonasal mucosa of chronic rhinosinusitis with polyp patients
Chronic rhinosinusitis (CRS) describes an inflammatory condition affecting the sinonasal mucosa. As the immune system players such as immunoglobulins play prominent roles in the development of CRS, we aimed to... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 25, 2020 Category: Allergy & Immunology Authors: Hossein Aazami, Farhad Seif, Babak Ghalehbaghi, Pegah Babaheidarian, Alireza Mohebbi, Aslan Ahmadi, Majid Khoshmirsafa, Sahand Ghalehbaghi, Babak Behnam, Kobra Zinat Entezami, Zahra Madjd and Reza Falak Tags: Research Source Type: research

Higher efficacy of rupatadine 20 mg and 10 mg versus placebo in patients with perennial allergic rhinitis: a pooled responder analysis
The clinical efficacy of rupatadine in terms of responders has not been previously explored in perennial allergic rhinitis (PAR). (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 23, 2020 Category: Allergy & Immunology Authors: Antonio Valero, I ñaki Izquierdo, Marek L. Kowalski, Glenis K. Scadding, Jean Bousquet and Joaquim Mullol Tags: Research Source Type: research

Severe eosinophilic asthma and aspirin-exacerbated respiratory disease associated to eosinophilic gastroenteritis treated with mepolizumab: a case report
Mepolizumab (MEP) is the first anti Interleukin (IL)-5 add-on therapy approved for the treatment of severe refractory eosinophilic asthma. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 22, 2020 Category: Allergy & Immunology Authors: C. Caruso, S. Colantuono, D. Pugliese, C. Di Mario, B. Tolusso, E. Gremese, G. Papparella, F. Castr ì, A. Gasbarrini, A. Romano and A. Armuzzi Tags: Case report Source Type: research

Billing fees for various common allergy tests vary widely across Canada
The prevalence of food allergy in Canada is high and has increased over time. To date, there are no Canadian data on the healthcare costs of visits to allergists. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 22, 2020 Category: Allergy & Immunology Authors: Jennifer Lisa Penner Protudjer, Lianne Soller, Elissa Michelle Abrams and Edmond S. Chan Tags: Research Source Type: research

In patients with severe asthma with eosinophilia in reslizumab clinical trials, high peripheral blood eosinophil levels are associated with low FEV1 reversibility
A post hoc analysis of two randomized, placebo –controlled, Phase 3 trials of intravenous reslizumab, an anti-interleukin-5 (IL-5) biologic for severe eosinophilic asthma. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 19, 2020 Category: Allergy & Immunology Authors: J. Christian Virchow, Lisa Hickey, Evelyn Du and Margaret Garin Tags: Short report Source Type: research

Protocol for a double-blind, randomized controlled trial on the dose-related efficacy of omalizumab in multi-food oral immunotherapy
Previous proof-of-concept studies have shown that a short course of omalizumab can safely accelerate the oral immunotherapy schedule for multiple allergens simultaneously. Considering the high cost of medicati... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 17, 2020 Category: Allergy & Immunology Authors: Alexandra Langlois, Marie-H élène Lavergne, Hélène Leroux, Kerstin Killer, Pauline Azzano, Louis Paradis, Kathryn Samaan, Jonathan Lacombe-Barrios, Benoît Mâsse, Anne Des Roches and Philippe Bégin Tags: Research Source Type: research

A case of allergy to Silybum marianum (milk thistle) and Eragrostis tef (teff)
This paper presents a peculiar first case of an allergy to Silybum marianum (milk thistle) and Eragrostis tef (teff). Both teff and milk thistle have been presented in the literature (both domestic and foreign... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 15, 2020 Category: Allergy & Immunology Authors: O. Wojas, E. Krzych-Fa łta, P. Samel-Kowalik, M. Żalikowska-Gardocka, E. Majsiak, A. Mari and B. Samoliński Tags: Case report Source Type: research

Epinephrine auto-injector needle length
Epinephrine auto-injectors are expected to deliver the drug intramuscularly. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 15, 2020 Category: Allergy & Immunology Authors: Sten Dreborg, Gina Tsai and Harold Kim Tags: Research Source Type: research

Activated phosphoinositide 3-kinase delta syndrome 1 and 2 (APDS 1 and APDS 2): similarities and differences based on clinical presentation in two boys
Activated PI3K delta syndrome (APDS) belongs to the heterogeneous group of primary immunodeficiency disorders (PIDs). Progress in next-generation sequencing (NGS) enabled identification of gain-of-function mut... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 1, 2020 Category: Allergy & Immunology Authors: Marlena Ewertowska, El żbieta Grześk, Anna Urbańczyk, Anna Dąbrowska, Katarzyna Bąbol-Pokora, Monika Łęcka and Sylwia Kołtan Tags: Case report Source Type: research

The presence of overlapping quality of life symptoms in primary antibody deficiency (PAD) and chronic fatigue syndrome (CFS)
This study aimed to determine th... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 30, 2020 Category: Allergy & Immunology Authors: Rhea A. Bansal, Susan Tadros and Amolak S. Bansal Tags: Research Source Type: research