A survey of severe asthma in Canada: results from the CASCADE practice reflective program
Since the last guidance was published by the Canadian Thoracic Society, there have been several advances in the clinical management of severe asthma. To gain a better understanding of the current standards of ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 18, 2024 Category: Allergy & Immunology Authors: Krystelle Godbout, Harold Kim, Irvin Mayers, James Paterson and Charles K. N. Chan Tags: Research Source Type: research

Effectiveness of immunoglobulin replacement therapy in preventing infections in patients with chronic obstructive pulmonary disease: a systematic review
Immunoglobulin replacement therapy is a standard treatment for patients with antibody production deficiencies, which is of interest in patients with chronic obstructive pulmonary disease (COPD). This systemati... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 10, 2024 Category: Allergy & Immunology Authors: Justin J. Y. Kim, Liz Dennett, Maria B. Ospina, Anne Hicks, Harissios Vliagoftis and Adil Adatia Tags: Research Source Type: research

A case of pediatric serum sickness like reaction (SSLR) after a 2-month re-exposure to amoxicillin
Serum-sickness like reactions (SSLRs) to amoxicillin have been documented in the medical literature. Beta-lactams are important and commonly used medications especially in the pediatric population. Often, SSLR... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 1, 2024 Category: Allergy & Immunology Authors: Devyani Bakshi, Xinxin Tang and Susan Waserman Tags: Case report Source Type: research

Hereditary or acquired? Comprehensive genetic testing assists in stratifying angioedema patients
This study focuses on the genetic basis of HAE, particularly focusing on unresolve... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 30, 2024 Category: Allergy & Immunology Authors: Marija Rozevska, Adine Kanepa, Signe Purina, Linda Gailite, Inga Nartisa, Henriette Farkas, Dmitrijs Rots and Natalja Kurjane Tags: Short report Source Type: research

Evaluation of adherence to guideline-directed therapy and risk factors for exacerbation in mild asthma: a retrospective chart review
A significant update was made to both the Global Initiative for Asthma (GINA) in 2019 and the National Heart Lung and Blood Institute (NHLBI) asthma guidelines in 2020 for mild asthma. These groups no longer r... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Beth A. Zerr, Jacklyn M. Kruse and Jon J. Glover Tags: Research Source Type: research

Elevated tryptase level in a child with idiopathic anaphylaxis: a case of hereditary alpha-tryptasemia
Hereditary alpha-tryptasemia (H αT) is an autosomal dominant disorder estimated to affect 5% of the population. High baseline tryptase level is a consistent finding, but there is a great variability of clinic m... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 27, 2024 Category: Allergy & Immunology Authors: Vicky Le Blanc and Wade T. A. Watson Tags: Case report Source Type: research

Real-world association between systemic corticosteroid exposure and complications in US patients with severe asthma
Systemic corticosteroid (SCS) use remains widespread among patients with severe asthma, despite associated complications. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 26, 2024 Category: Allergy & Immunology Authors: Thomas B Casale, Thomas Corbridge, Guillaume Germain, Fran çois Laliberté, Sean D MacKnight, Julien Boudreau, Mei S Duh and Arijita Deb Tags: Research Source Type: research

Pediatric emergency department-based asthma education tools and parent/child asthma knowledge
Asthma exacerbations are a leading cause of pediatric hospitalizations despite multiple efforts to educate patients and families on disease course and medication management. Asthma education in the pediatric e... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 25, 2024 Category: Allergy & Immunology Authors: Kina Goodman, Rosa I. Arriaga, Rawan Korman, Farzina Zafar, Cal Stephens, Polly Kumari, Karthika Jayaprakash, Anne M. Fitzpatrick, Nicholas Cooper and Claudia R. Morris Tags: Letter to the editor Source Type: research

The role of molecular diagnosis in anaphylactic patients with dual or triple-sensitization to Hymenoptera venoms
The objective of this study was to determine the culprit allergen in ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 23, 2024 Category: Allergy & Immunology Authors: Mohammad Hassan Bemanian, Raheleh Shokouhi Shoormasti, Saba Arshi, Mahsa Jafari, Sima Shokri, Morteza Fallahpour, Mohammad Nabavi and Fatemeh Zaremehrjardi Tags: Research Source Type: research

Circ_0070934 promotes MGAT3 expression and inhibits epithelial-mesenchymal transition in bronchial epithelial cells by sponging miR-199a-5p
The objective of this investigation was to elucidate the functional dynamics of the circ_0070934... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 23, 2024 Category: Allergy & Immunology Authors: Ziqi Ding, Xinru Xiao, Liang Fan, Zhengdao Mao, Chuang Sun, Na Li and Qian Zhang Tags: Research Source Type: research

Infantile atopic dermatitis – increasing severity predicts negative impacts on maternal and infant sleep: a mixed methods study
While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Zoe Harbottle, Amanda N ötzel, Michael A. Golding, Manvir Bhamra, Isac Kopsch, Erik Wilking, Marina Jonsson, Elissa M. Abrams, Michelle A. Halbrich, Elinor Simons, Leslie E. Roos, Jill A. Keddy-Grant, Thomas V. Gerstner, Jo-Anne St-Vincent, Sandra Ekstrà Tags: Research Source Type: research

2023 CSACI annual scientific meeting book of abstracts
(Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 5, 2024 Category: Allergy & Immunology Tags: Meeting Abstracts Source Type: research

Eosinophilic gastritis and gluten-sensitive enteropathy manifested as hypoproteinemia and treated with omalizumab: a case report
Eosinophilic gastritis (EoG) has rarely been reported in conjunction with gluten-sensitive enteropathy (GSE). When this does occur, patients typically present with gastrointestinal symptoms. To our knowledge, ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 5, 2024 Category: Allergy & Immunology Authors: Zhirong Du, Zixi Wang, Weixun Zhou, Jia Yin and Yuxiang Zhi Tags: Case report Source Type: research

Introduction of a penicillin allergy de-labelling program with direct oral challenge and its effects on utilization of beta-lactam antimicrobials: a multicenter retrospective parallel cohort study
Self-reported penicillin allergy labels are common and often inaccurate after assessment. These labels can lead to reduced use of first-line beta-lactam antibiotics and worse outcomes. We measured the impact o... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - March 5, 2024 Category: Allergy & Immunology Authors: Adhora Mir, Derek Lanoue, Veronica Zanichelli, Carl van Walraven, Timothy Olynych, Caroline Nott and Derek MacFadden Tags: Research Source Type: research

The chronic rhinosinusitis with nasal polyp patient journey in the United States and Europe
In this letter to the editor, we present questionnaire-based data assessing the patient journey of adults with moderate –severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in the USA and five European cou... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 26, 2024 Category: Allergy & Immunology Authors: Jeremiah Hwee, Lauren Lee, Mark Small, Steven G. Smith, Victoria S. Benson and Shiyuan Zhang Tags: Letter to the editor Source Type: research