Aspergillus sensitization and aspergillus-associated diseases in a sample of patients with severe asthma
Conclusions: The severe asthmatic patients examined had a high prevalence of Aspergillus sensitization and of Aspergillus-associated diseases as ABPA (26%) and CPA (26%). It has to be demonstrated the benefit of an early recognition and treatment of these diseases on the course of asthma.
AbstractNumerous studies have shown that microbiomes play an important role in the pathogenesis of chronic rhinosinusitis (CRS). In addition to a known short pentraxin, C-reactive protein, long pentraxin 3 (PTX3) belongs to pentraxin family which detects conserved microbial pentraxin motifs and mobilizes early defense against foreign invaders, but its participation in CRS remains unclear. In the present study, through an intensive screening, peptidoglycan (PGN) was selected as a main material to investigate the action mechanism of a cell wall component on CRS without nasal polyps (CRSsNP) nasal mucosa-derived fibroblasts a...
Is it time to change our public health message and suggest that everyone wear a mask? Dr Amy Baxter offers her arguments in support of change.Medscape Public Health
Findings from a large Swedish cohort show that any subtype of polyps will increase the risk for colorectal cancer, but only certain types raise the risk for cancer-related mortality.Medscape Medical News
By now, you’ve probably heard this warning about the new coronavirus pandemic: those who are older and have a chronic medical condition are at increased risk for severe disease and death. If you fall into this category, here’s important information about the coronavirus outbreak tailored to you. If you look at the data, older adults and those with chronic health problems who get COVID-19 are more likely to require hospitalization and admission to an intensive care unit. And so far in the US, 80% of the deaths from the new coronavirus virus have occurred in people who were older. But this raises a number of ques...
Condition: Cow's Milk Allergy Intervention: Sponsor: Assiut University Not yet recruiting
Conditions: Plasmodium Falciparum Infection; Malaria Interventions: Biological: VRC-MALMAB0100-00-AB (CIS43LS); Other: Normal saline Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); Malaria Research and Training Center; Faculté de Médecine Pharmacie d'Odontostomatologie; University of Sciences, Techniques,&Technologies of Bamako (USTTB); Vaccine Research Center; University of Washington; Harvard School of Public Health Not yet recruiting
Condition: Allergy;Food Intervention: Sponsor: Central Hospital, Nancy, France Not yet recruiting
With all the preparations, it was hoped that Paris would be at the optimistic end of predictions for the COVID-19 epidemic, but as the weeks pass, it looks more and more like a catastrophe is coming.Medscape Medical News
Conclusions.SCIT with house dust mixture of ROXALL Medicina España S.A. seems to have an acceptable tolerability profile, induces blocking IgG and decreases skin reactivity. PMID: 32223886 [PubMed - as supplied by publisher]
Publication date: Available online 31 March 2020Source: Fungal BiologyAuthor(s): Jan Dijksterhuis, Wim van Egmond, Andrew Yarwood