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William Ernest Dismukes 1939-2017
William Ernest Dismukes 1939-2017Post date: Wednesday, December 13, 2017 - 11:18Images (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 13, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Maintaining Food Safety Standards Regarding Mycotics in the Poultry Industry
Tuesday, December 12, 2017 - 13:27Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Achieving antimicrobial resistance (AMR) goals through better fungal diagnostic in Pakistan
Tuesday, December 12, 2017 - 13:25Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Impact of fungi on animal and food sector
Tuesday, December 12, 2017 - 13:18Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Fungal Infections in Pakistan - Local Challenges
Tuesday, December 12, 2017 - 13:13Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Pulmonary fungal infections and susceptible hosts
Tuesday, December 12, 2017 - 13:10Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Pulmonary fungal infections and susceptible hosts
Tuesday, December 12, 2017 - 09:29Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Molecular Mycology (MOMY): Current Approaches to Fungal Pathogenesis
Fungal diseases are significant causes of mortality and morbidity in both the developed and the developing world. The recent increases in the incidence and severity of invasive fungal infections are directly attributable to new susceptible patient populations. Examples of these large, at-risk populations include patients with AIDS; hospitalized patients being treated for cancer and autoimmune disorders; andthose receiving organ transplants.Courses& Workshops (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Invasive Pulmonary Mycoses in Lung Transplant Recipients
Tuesday, December 12, 2017 - 08:26Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 12, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

The Complex Kingdom of Fungi, and the Story Behind Bay Area Amanita Phalloides: Part 3
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 6, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

The Complex Kingdom of Fungi, and the Story Behind Bay Area Amanita Phalloides
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 6, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

The Complex Kingdom of Fungi, and the Story Behind Bay Area Amanita Phalloides: Part 2
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 6, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

The Complex Kingdom of Fungi, and the Story Behind Bay Area Amanita Phalloides: Part 1
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 6, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

The Complex Kingdom of Fungi, and the Story Behind Bay Area Amanita Phalloides
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 6, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Antarctic birds ’ nests home to Amphotericin B resistant fungi
Antarctic birds ’ nests home to Amphotericin B resistant fungiMon, 12/04/2017 - 08:00News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 4, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

New formulation SUBA-itraconazole prophylaxis – therapeutic levels, safety and tolerability
New formulation SUBA-itraconazole prophylaxis – therapeutic levels, safety and tolerabilityThu, 11/30/2017 - 13:25News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 30, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Senior Clinical Pharmacist - Antibiotics (band 7)
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 28, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Research Associate in Microbial Engineering and Synthetic Biology
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 28, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Specialist Antifungal Pharmacist Band 8b
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 28, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Academic Clinical Fellowship
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 28, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

First UK case reported of fungal lettuce wilt (Fusarium oxysporum f.sp. lactucae)
Tue, 11/28/2017 - 11:25News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 28, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

PhD Studentship: Population Drivers, Demographics and Disease In Wild Snake Populations
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 27, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

BBSRC PhD Studentship: Modelling Climate Change Impacts on Mycotoxin Contamination of Coffee
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 27, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Panfungal DNA sequencing assay for invasive fungal infections shows good sensitivity (97%) and specificity (98%)
Mon, 11/27/2017 - 12:21News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 27, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Evaluating CT guided lung biopsies for diagnosing fungal infection
Wed, 11/22/2017 - 11:23News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 22, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

First CPAnet symposium identifies four key research areas for chronic pulmonary aspergillosis
Thu, 11/16/2017 - 15:40News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

ImmunoPET: the future of lung scans in aspergillosis?
Wed, 11/15/2017 - 11:48News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 15, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

11th Healthcare Infection Society International Conference
Date: Tuesday, November 14, 2017Year: 2018Location: Arena and Convention Centre, LiverpoolContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 14, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

45th Annual Meeting of the European Society for Blood and Marrow Transplantation
Date: Monday, November 13, 2017Year: 2019Location: Frankfurt, GermanyContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 13, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Unravelling the pharmacokinetics of triazole antifungals in snakes
Thu, 11/09/2017 - 15:50News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 9, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

First case of echinocandin resistance caused by fks1 mutation found in Aspergillus
Tue, 11/07/2017 - 15:10News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 7, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Vitamin D deficiency and aspergillosis
Mon, 11/06/2017 - 17:31News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 6, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

A. terreus conidia use dendritic cells to their advantage
Thu, 11/02/2017 - 08:35News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 2, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Preclinical Evaluation of the Stability, Safety and Efficacy of CD101, a Novel Echinocandin
Fungal infections pose a significant public health burden with high morbidity and mortality. CD101 is a novel echinocandin under development for the treatment and prevention of systemic Candida infections. Preclinical studies were conducted to evaluate the metabolic stability, plasma protein binding, pharmacokinetics, toxicity, and efficacy of CD101 at various dose levels. CD101 was stable to biotransformation in rat/monkey/human liver microsomes and rat/monkey/dog/human hepatocytes. (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 1, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Postdoctoral research positions
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 1, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Postdoctoral Research Associate I
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 1, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Jekyll-and-Hyde yeast makes chocolate taste great but also causes opportunistic infections
Tue, 10/31/2017 - 16:43News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 31, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

MRC PhD studentship: Definition of the key fungal components that trigger dendritic cells to mediate allergic inflammation
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 30, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Could gamers help tackle aflatoxins?
Fri, 10/27/2017 - 13:57News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 27, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Did Ötzi the Iceman have aspergillosis?
Did Ötzi the Iceman have aspergillosis?Wed, 10/25/2017 - 12:46News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 25, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

59th American Society of Hematology Annual Meeting and Exposition
Date: Tuesday, October 24, 2017Year: 2017Location: Atlanta, USAContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 24, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

North American Cystic Fibrosis Conference 2017
Date: Tuesday, October 24, 2017Year: 2017Location: Indianapolis, USAContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 24, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

British Thoracic Society Summer Meeting 2018
Date: Tuesday, October 24, 2017Year: 2018Location: Manchester, UKContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 24, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

41st European Cystic Fibrosis Conference
Date: Tuesday, October 24, 2017Year: 2018Location: Belgrade, SerbiaContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 24, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

44th Annual Meeting of the European Society for Blood and Marrow Transplantation
Date: Tuesday, October 24, 2017Year: 2018Location: Lisbon, PortugalContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 24, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

New and emerging treatments for fungal infections.
Although several new antifungal drugs have been licensed in the last 5 years, some patients remain difficult to treat. The main reasons for this include intrinsic or acquired antifungal resistance, organ dysfunction preventing the use of some agents and drug interactions. In addition, some drugs penetrate poorly into sanctuary sites including eye and urine, and others are associated with considerable adverse events. Here, we review the preclinical and clinical development progress with four new antifungal agents: isavuconazole, ravuconazole,albaconazole and aminocandin. (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 20, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Biafungin (CD101), a Novel Echinocandin, Displays a Long Half-life in the Chimpanzee, Suggesting a Once-Weekly IV Dosing Option
Background: The echinocandins are an important class of antifungal agents, but are administered oncedaily by intravenous (IV) infusion. An echinocandin that could be administered once weekly couldfacilitate earlier hospital discharges and could expand usage to indications where daily infusions areimpractical. Biafungin is a highly stable echinocandin for once-weekly IV administration. The compoundwas found to have a spectrum of activity and potency comparable to other echinocandins. In (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 20, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Biafungin (CD101), a Novel Echinocandin, Displays an Uncommonly Long Half-life in Multiple Species
Background: The echinocandins are an important class of antifungal agents, but areadministered once daily by intravenous (IV) infusion. An echinocandin that offers a convenientand more economic dosing schedule is desired.Biafungin is a highly stable echinocandin for intermittent IV administration. The compound wasfound to have a long half-life (T1/2), which may greatly reduce costs even as an IV therapythrough less frequent dosing, allowing earlier discharges for patients with negative fungal (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 20, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

C101 (biafungin) entry on BIOCENTURY
: http://bciq.biocentury.com/products/biafungin (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 20, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species
Novelmacrocyclic amidinourea derivatives 11, 18, and 25 were synthesized and evaluated as antifungal agentsagainstwild-type and fluconazoleresistantCandidaspecies. (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 20, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news