The Influence of the COVID-19 Pandemic on Intensivists' Well-Being: A Qualitative Study
Chest. 2022 May 11:S0012-3692(22)00898-4. doi: 10.1016/j.chest.2022.05.003. Online ahead of print.ABSTRACTBACKGROUND: The COVID-19 pandemic has strained healthcare systems and resulted in widespread critical care staffing shortages, negatively impacting quality of care delivered.RESEARCH QUESTION: How have hospitals' emergency responses to the pandemic influenced the well-being of frontline intensivists, and are there any potential strategies to improve their well-being and help preserve the critical care workforce?STUDY DESIGN AND METHODS: We performed semi-structured interviews of intensivists at clusters of tertiary and...
Source: Chest - May 14, 2022 Category: Respiratory Medicine Authors: Kelly C Vranas Sara E Golden Shannon Nugent Thomas S Valley Amanda Schutz Abhijit Duggal Kevin P Seitz Steven Y Chang Christopher G Slatore Donald R Sullivan Catherine L Hough Kusum S Mathews Source Type: research

The Influence of the COVID-19 Pandemic on Intensivists' Well-Being: A Qualitative Study
Chest. 2022 May 11:S0012-3692(22)00898-4. doi: 10.1016/j.chest.2022.05.003. Online ahead of print.ABSTRACTBACKGROUND: The COVID-19 pandemic has strained healthcare systems and resulted in widespread critical care staffing shortages, negatively impacting quality of care delivered.RESEARCH QUESTION: How have hospitals' emergency responses to the pandemic influenced the well-being of frontline intensivists, and are there any potential strategies to improve their well-being and help preserve the critical care workforce?STUDY DESIGN AND METHODS: We performed semi-structured interviews of intensivists at clusters of tertiary and...
Source: Chest - May 14, 2022 Category: Respiratory Medicine Authors: Kelly C Vranas Sara E Golden Shannon Nugent Thomas S Valley Amanda Schutz Abhijit Duggal Kevin P Seitz Steven Y Chang Christopher G Slatore Donald R Sullivan Catherine L Hough Kusum S Mathews Source Type: research

The Influence of the COVID-19 Pandemic on Intensivists' Well-Being: A Qualitative Study
Chest. 2022 May 11:S0012-3692(22)00898-4. doi: 10.1016/j.chest.2022.05.003. Online ahead of print.ABSTRACTBACKGROUND: The COVID-19 pandemic has strained healthcare systems and resulted in widespread critical care staffing shortages, negatively impacting quality of care delivered.RESEARCH QUESTION: How have hospitals' emergency responses to the pandemic influenced the well-being of frontline intensivists, and are there any potential strategies to improve their well-being and help preserve the critical care workforce?STUDY DESIGN AND METHODS: We performed semi-structured interviews of intensivists at clusters of tertiary and...
Source: Chest - May 14, 2022 Category: Respiratory Medicine Authors: Kelly C Vranas Sara E Golden Shannon Nugent Thomas S Valley Amanda Schutz Abhijit Duggal Kevin P Seitz Steven Y Chang Christopher G Slatore Donald R Sullivan Catherine L Hough Kusum S Mathews Source Type: research

COUNTERPOINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? No
Chest. 2022 Mar 15:S0012-3692(22)00201-X. doi: 10.1016/j.chest.2022.01.037. Online ahead of print.NO ABSTRACTPMID:35550714 | PMC:PMC8923523 | DOI:10.1016/j.chest.2022.01.037 (Source: Chest)
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: David Jimenez Parth Rali Kevin Doerschug Source Type: research

Natural History of Contralateral Bullae/Blebs After Ipsilateral Video-Assisted Thoracoscopic Surgery for Primary Spontaneous Pneumothorax: A Retrospective Cohort Study
Chest. 2022 May 10:S0012-3692(22)00896-0. doi: 10.1016/j.chest.2022.05.001. Online ahead of print.ABSTRACTBACKGROUND: Contralateral bullae/blebs are frequently found in patients who are scheduled to undergo ipsilateral video-assisted thoracoscopic surgery (VATS) for primary spontaneous pneumothorax (PSP).RESEARCH QUESTION: Should visible contralateral bullae/blebs be simultaneously resected when ipsilateral VATS bullectomy is performed?STUDY DESIGN AND METHODS: In this single-center, retrospective cohort study, we included patients aged ≤30 years who underwent ipsilateral VATS for PSP from April 2009 to December 2019. El...
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: Jin Yong Jeong Ah Young Shin Jick Hwan Ha Jong Hui Suh Si Young Choi Ju Sang Kim Chan Beom Park Source Type: research

Association of Right Ventricular Afterload with Atrial Fibrillation Risk in Older Adults: The Atherosclerosis Risk in Communities Study
Chest. 2022 May 10:S0012-3692(22)00899-6. doi: 10.1016/j.chest.2022.05.004. Online ahead of print.ABSTRACTBACKGROUND: Atrial fibrillation (AF) is widely perceived to originate from the left atrium (LA). It is unclear whether increases in right ventricular (RV) afterload in older adults plays an etiological role in AF genesis independent of LA and left ventricular (LV) remodeling.RESEARCH QUESTION: Is higher RV afterload associated with greater AF risk independent of LA and LV remodeling?STUDY DESIGN AND METHODS: In this observational prospective study, we included 2246 community-dwelling older adults (mean age, 75 years) w...
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: Romil R Parikh Faye L Norby Wendy Wang Thenappan Thenappan Kurt W Prins Jeremy R Van't Hof Pamela L Lutsey Scott D Solomon Amil M Shah Lin Yee Chen Source Type: research

Impact of preoperative diagnostic biopsy procedure on spread through air spaces and related outcomes in resected stage I non-small cell lung cancer
This study aimed to analyze the unexplored correlation between preoperative biopsy procedure and a higher risk of STAS and its impact on STAS-related outcomes in resected stage I non-small cell lung cancer (NSCLC).RESEARCH QUESTION: Does preoperative biopsy procedure affect the risk of STAS and STAS-related outcomes in surgically treated stage I NSCLC?STUDY DESIGN AND METHODS: We examined 2,169 patients who underwent surgery for pathologic stage I NSCLC during January 2011-December 2019 at the Seoul National University Bundang Hospital, a tertiary center in South Korea. Factors including percutaneous needle biopsy (PCNB) a...
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: Ga Young Lee Jin-Haeng Chung Sukki Cho Yeon Bi Han Young Mi Park Hyung-Jun Kim Myung Jin Song Byoung Soo Kwon Sung Yoon Lim Yeon Joo Lee Jong Sun Park Young-Jae Cho Ho Il Yoon Jae Ho Lee Choon-Taek Lee Yeon Wook Kim Source Type: research

COUNTERPOINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? No
Chest. 2022 Mar 15:S0012-3692(22)00201-X. doi: 10.1016/j.chest.2022.01.037. Online ahead of print.NO ABSTRACTPMID:35550714 | DOI:10.1016/j.chest.2022.01.037 (Source: Chest)
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: David Jimenez Parth Rali Kevin Doerschug Source Type: research

Natural History of Contralateral Bullae/Blebs After Ipsilateral Video-Assisted Thoracoscopic Surgery for Primary Spontaneous Pneumothorax: A Retrospective Cohort Study
Chest. 2022 May 10:S0012-3692(22)00896-0. doi: 10.1016/j.chest.2022.05.001. Online ahead of print.ABSTRACTBACKGROUND: Contralateral bullae/blebs are frequently found in patients who are scheduled to undergo ipsilateral video-assisted thoracoscopic surgery (VATS) for primary spontaneous pneumothorax (PSP).RESEARCH QUESTION: Should visible contralateral bullae/blebs be simultaneously resected when ipsilateral VATS bullectomy is performed?STUDY DESIGN AND METHODS: In this single-center, retrospective cohort study, we included patients aged ≤30 years who underwent ipsilateral VATS for PSP from April 2009 to December 2019. El...
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: Jin Yong Jeong Ah Young Shin Jick Hwan Ha Jong Hui Suh Si Young Choi Ju Sang Kim Chan Beom Park Source Type: research

Association of Right Ventricular Afterload with Atrial Fibrillation Risk in Older Adults: The Atherosclerosis Risk in Communities Study
Chest. 2022 May 10:S0012-3692(22)00899-6. doi: 10.1016/j.chest.2022.05.004. Online ahead of print.ABSTRACTBACKGROUND: Atrial fibrillation (AF) is widely perceived to originate from the left atrium (LA). It is unclear whether increases in right ventricular (RV) afterload in older adults plays an etiological role in AF genesis independent of LA and left ventricular (LV) remodeling.RESEARCH QUESTION: Is higher RV afterload associated with greater AF risk independent of LA and LV remodeling?STUDY DESIGN AND METHODS: In this observational prospective study, we included 2246 community-dwelling older adults (mean age, 75 years) w...
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: Romil R Parikh Faye L Norby Wendy Wang Thenappan Thenappan Kurt W Prins Jeremy R Van't Hof Pamela L Lutsey Scott D Solomon Amil M Shah Lin Yee Chen Source Type: research

Impact of preoperative diagnostic biopsy procedure on spread through air spaces and related outcomes in resected stage I non-small cell lung cancer
This study aimed to analyze the unexplored correlation between preoperative biopsy procedure and a higher risk of STAS and its impact on STAS-related outcomes in resected stage I non-small cell lung cancer (NSCLC).RESEARCH QUESTION: Does preoperative biopsy procedure affect the risk of STAS and STAS-related outcomes in surgically treated stage I NSCLC?STUDY DESIGN AND METHODS: We examined 2,169 patients who underwent surgery for pathologic stage I NSCLC during January 2011-December 2019 at the Seoul National University Bundang Hospital, a tertiary center in South Korea. Factors including percutaneous needle biopsy (PCNB) a...
Source: Chest - May 13, 2022 Category: Respiratory Medicine Authors: Ga Young Lee Jin-Haeng Chung Sukki Cho Yeon Bi Han Young Mi Park Hyung-Jun Kim Myung Jin Song Byoung Soo Kwon Sung Yoon Lim Yeon Joo Lee Jong Sun Park Young-Jae Cho Ho Il Yoon Jae Ho Lee Choon-Taek Lee Yeon Wook Kim Source Type: research

Cannabinoids, insomnia, and other sleep disorders
Chest. 2022 May 7:S0012-3692(22)00895-9. doi: 10.1016/j.chest.2022.04.151. Online ahead of print.ABSTRACTSleep disturbances are often cited as a primary reason for medicinal cannabis use and there is increasing clinical interest in the therapeutic potential of cannabinoids in treating sleep disorders. Burgeoning evidence suggests a role of the endocannabinoid system in regulating the circadian sleep-wake cycle, highlighting a potential avenue for developing novel therapeutics. Despite widespread use of cannabis products as sleep aids globally, robustly designed studies verifying efficacy in sleep-disordered populations are...
Source: Chest - May 10, 2022 Category: Respiratory Medicine Authors: Isobel Lavender Iain S McGregor Anastasia Suraev Ronald R Grunstein Camilla M Hoyos Source Type: research

Cannabinoids, insomnia, and other sleep disorders
Chest. 2022 May 7:S0012-3692(22)00895-9. doi: 10.1016/j.chest.2022.04.151. Online ahead of print.ABSTRACTSleep disturbances are often cited as a primary reason for medicinal cannabis use and there is increasing clinical interest in the therapeutic potential of cannabinoids in treating sleep disorders. Burgeoning evidence suggests a role of the endocannabinoid system in regulating the circadian sleep-wake cycle, highlighting a potential avenue for developing novel therapeutics. Despite widespread use of cannabis products as sleep aids globally, robustly designed studies verifying efficacy in sleep-disordered populations are...
Source: Chest - May 10, 2022 Category: Respiratory Medicine Authors: Isobel Lavender Iain S McGregor Anastasia Suraev Ronald R Grunstein Camilla M Hoyos Source Type: research

Cannabinoids, insomnia, and other sleep disorders
Chest. 2022 May 7:S0012-3692(22)00895-9. doi: 10.1016/j.chest.2022.04.151. Online ahead of print.ABSTRACTSleep disturbances are often cited as a primary reason for medicinal cannabis use and there is increasing clinical interest in the therapeutic potential of cannabinoids in treating sleep disorders. Burgeoning evidence suggests a role of the endocannabinoid system in regulating the circadian sleep-wake cycle, highlighting a potential avenue for developing novel therapeutics. Despite widespread use of cannabis products as sleep aids globally, robustly designed studies verifying efficacy in sleep-disordered populations are...
Source: Chest - May 10, 2022 Category: Respiratory Medicine Authors: Isobel Lavender Iain S McGregor Anastasia Suraev Ronald R Grunstein Camilla M Hoyos Source Type: research

Comparison of heart rate after phenylephrine versus norepinephrine initiation in patients with septic shock and atrial fibrillation
Chest. 2022 May 5:S0012-3692(22)00891-1. doi: 10.1016/j.chest.2022.04.147. Online ahead of print.ABSTRACTBACKGROUND: Atrial fibrillation (AF) is a common complication of sepsis. It is unclear if norepinephrine, an α- and β-agonist, and phenylephrine, an α-agonist, are associated with different heart rates among patients with sepsis and AF.RESEARCH QUESTION: Among patients with sepsis and AF, what is the difference in heart rate after phenylephrine initiation versus norepinephrine initiation?STUDY DESIGN AND METHODS: Using the Medical Information Mart in Intensive Care (MIMIC)-IV database, we identified patients with sep...
Source: Chest - May 8, 2022 Category: Respiratory Medicine Authors: Anica C Law Nicholas A Bosch Daniel Peterson Allan J Walkey Source Type: research