Sub-Lobar Resection, Stereotactic Body Radiation Therapy, and Percutaneous Ablation Provide Comparable Outcomes for Lung Metastasis-Directed Therapy
Chest. 2023 Dec 14:S0012-3692(23)05853-1. doi: 10.1016/j.chest.2023.12.013. Online ahead of print.ABSTRACTBACKGROUND: Prolonged survival of patients with metastatic disease has furthered interest in metastasis-directed therapy (MDT).RESEARCH QUESTION: There is a paucity of data comparing lung MDT modalities. Do outcomes among sub-lobar resection (SLR), stereotactic body radiation therapy (SBRT), and percutaneous ablation (PA) for lung metastases vary in terms of local control and survival?STUDY DESIGN AND METHODS: Medical records of patients undergoing lung MDT at a single cancer center between January 2015 and December 20...
Source: Chest - December 16, 2023 Category: Respiratory Medicine Authors: Hunter C Gits Mitra A Khosravi Flanigan Jamie D Kapplinger Janani S Reisenauer Patrick W Eiken William G Breen Linh H Vu Brian T Welch William S Harmsen Courtney N Day Kenneth R Olivier Sean S Park Yolanda I Garces Christopher L Hallemeier Kenneth W Merre Source Type: research
Time-limited trials for patients with critical illness: a review of the literature
Chest. 2023 Dec 13:S0012-3692(23)05855-5. doi: 10.1016/j.chest.2023.12.014. Online ahead of print.ABSTRACTTOPIC IMPORTANCE: Since the 1990s, "time-limited trials" have been described as an approach to navigate uncertain benefits and limits of life-sustaining therapies in patients with critical illness. In this review, we aim to synthesize the evidence on time-limited trials in critical care, establish what is known, and highlight important knowledge gaps.REVIEW FINDINGS: We identified 18 empirical studies and 15 ethical analyses about time-limited trials in patients with critical illness. Observational studies suggest time...
Source: Chest - December 15, 2023 Category: Respiratory Medicine Authors: Jacqueline M Kruser Nandita R Nadig Elizabeth M Viglianti Justin T Clapp Katharine E Secunda Scott D Halpern Source Type: research
Time-limited trials for patients with critical illness: a review of the literature
Chest. 2023 Dec 13:S0012-3692(23)05855-5. doi: 10.1016/j.chest.2023.12.014. Online ahead of print.ABSTRACTTOPIC IMPORTANCE: Since the 1990s, "time-limited trials" have been described as an approach to navigate uncertain benefits and limits of life-sustaining therapies in patients with critical illness. In this review, we aim to synthesize the evidence on time-limited trials in critical care, establish what is known, and highlight important knowledge gaps.REVIEW FINDINGS: We identified 18 empirical studies and 15 ethical analyses about time-limited trials in patients with critical illness. Observational studies suggest time...
Source: Chest - December 15, 2023 Category: Respiratory Medicine Authors: Jacqueline M Kruser Nandita R Nadig Elizabeth M Viglianti Justin T Clapp Katharine E Secunda Scott D Halpern Source Type: research
Effects of Negative Pressure Ventilation on Lung Volume and Airflow in Drug Induced Sleep Endoscopy
Chest. 2023 Dec 12:S0012-3692(23)05848-8. doi: 10.1016/j.chest.2023.12.008. Online ahead of print.NO ABSTRACTPMID:38097165 | DOI:10.1016/j.chest.2023.12.008 (Source: Chest)
Source: Chest - December 14, 2023 Category: Respiratory Medicine Authors: Jason L Yu Jack M Plageman Katherine P Gouldman Donald L Bliwise Alan R Schwartz Source Type: research
Effects of Negative Pressure Ventilation on Lung Volume and Airflow in Drug Induced Sleep Endoscopy
Chest. 2023 Dec 12:S0012-3692(23)05848-8. doi: 10.1016/j.chest.2023.12.008. Online ahead of print.NO ABSTRACTPMID:38097165 | DOI:10.1016/j.chest.2023.12.008 (Source: Chest)
Source: Chest - December 14, 2023 Category: Respiratory Medicine Authors: Jason L Yu Jack M Plageman Katherine P Gouldman Donald L Bliwise Alan R Schwartz Source Type: research
