Cross-cultural validation of the Portuguese from Portugal version of the test for respiratory and asthma control in kids questionnaire.
Conclusions. The Portuguese version of the TRACK questionnaire is accurate and reliable for monitoring asthma control. Its use may help to overcome challenges with the management of this age group. PMID: 33182989 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Opinions of patients with persistent asthma regarding the use of mobile applications for disease monitoring.
Conclusions. Most participants had uncontrolled asthma, reported high adherence to treatment and were daily users of social networks and the internet. Only 1/4 used apps but 2/3 would like to use apps to support asthma management. PMID: 33182990 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Allergic rhinits: impact on quality of life of adolescents.
Authors: Rosario CS, Murrieta-Aguttes M, Rosario NA Abstract Summary: Adolescence is one of the most rapid phases of human development, in which biological maturity precedes psychosocial maturity. Rhinoconjunctivitis (ARC) is present in around 15 percent of 13-14-year-old children, which indicates a higher prevalence when compared with 6-7-year-old children (8.5 percent). During childhood (0-10 years) prevalence of Allergic Rhinitis (AR) is higher among males compared to females. Quite the reverse, during adolescence (11-17 years) females display higher prevalence of AR compared to males. However, when they reach a...
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

The diverse roles of T cell subsets in asthma.
Authors: Regateiro FS, Botelho Alves P, Moura AL, Azevedo JP, Regateiro DT Abstract Summary: T cells are coordinators of the immune response and have been shown to play a central role in the pathophysiology of asthma. A good understanding of the T cells functions in asthma is important for therapeutic reasons, in particular for the choice of biological treatments in severe asthma. Although classically considered a Th2 disease, it is now clear that other types of T cells contribute for the pathophysiology and the heterogeneity of asthma. We here review how the different subsets of T cells are involved in the differe...
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Allergic sensitization to storage dust mites: a prospective study of patients with respiratory allergy.
Conclusions. Our study suggests that our population, independently of their occupational exposure and place of residency, are sensitized to SDM and that evaluation of sensitization to SDM should be considered as standard practice. PMID: 33191715 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Primary immunodeficiency disorder.
Conclusions. SCIG treatment provides ideal and protective immunoglobulin levels and offers the comfort of treatment in their home environment, thus increasing the patient's satisfaction and quality of life. PMID: 33191716 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Interleukin 13 gene polymorphism and susceptibility to asthma: a meta-regression and meta-analysis.
Conclusions. Both rs20541 and rs1800925 polymorphisms of IL13 gene confers a risk factor for asthma in different populations. PMID: 33191717 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Allergen immunotherapy in children with otitis media with effusion: a preliminary experience.
Authors: La Mantia I, Varricchio A, Ciprandi G PMID: 33191718 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

What do asthmatic patients think about telemedicine visits?
Discussion and conclusions. Our survey revealed that small changes could further increase patients' satisfaction, adherence, and confidence in telemedicine. Although presenting some limitations, virtual visits seem to be generally well accepted by asthmatic patients and it might be a good alternative for in-person visits, at least in such difficult times when social distancing is recommended. PMID: 33191719 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - November 17, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Urticaria and coronavirus infection: a lesson from SARS-CoV-2 pandemic.
Authors: Allegra A, Asero R, Giovannetti A, Isola S, Gangemi S Abstract Summary: Urticaria is a condition involving both skin and mucosal tissues characterized by the presence of wheals and/or angioedema. The acute form has been related to allergic reactions to drugs or foods, interaction with chemicals, or infections. We reviewed the association of urticaria with coronavirus infections. This review was carried out by the use of two search engines for published original articles, employing two key terms correlated to urticaria and viruses: "urticaria" and one term linked to each virus. The research of the...
Source: European Annals of Allergy and Clinical Immunology - October 11, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Omalizumab in severe chronic urticaria: are slow and non-responders different?
Conclusions. Patients with severe CSU showing a slow response or not responding at all to omalizumab show impressive similarities. It is currently not possible to predict whether patients with severe CSU and low IgE levels will show a slow response or will not respond to anti-IgE treatment. PMID: 32914943 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - September 12, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Immune signature of CCR7 + central memory T cells associates with disease severity and Immunoglobulin E in bronchial asthma.
Conclusions. These findings suggest that increased CCR4 + CD4 + T cells and CCR7 + memory CD4 + T cells (Tcm) may be associated with BA severity, especially in allergic BA patients and can potentially contribute to the rational design of new therapeutic approaches for asthma in the future. PMID: 32914944 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - September 12, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Angiotensin Converting Enzyme-2 (ACE2) receptors, asthma and severe COVID-19 infection risk.
Authors: Öztürk AB, Çağlayan B PMID: 32914945 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - September 12, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Does maternal diet during pregnancy influence clinical and laboratory characteristics of infantile-onset atopic dermatitis?
Conclusions. Our preliminary findings suggest that maternal egg intake during pregnancy might be a factor influencing laboratory markers of atopy in ofsprings. Prospective cohort studies are needed to confirm and clarify this relationship. PMID: 32914946 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - September 12, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

The treatment of allergic rhinitis in asthmatic children and adolescents: practical outcomes from the real-world "ControL'Asma" study.
The treatment of allergic rhinitis in asthmatic children and adolescents: practical outcomes from the real-world "ControL'Asma" study. Eur Ann Allergy Clin Immunol. 2020 Sep 11;: Authors: Tosca MA, Marseglia GL, Ciprandi G, Anastasio E, Brambilla I, Caffarelli C, Chini L, Ciprandi R, De Vittori V, Duse M, Di Cicco ME, Indinnimeo L, Kantar A, Leone M, Licari A, Marinelli G, Moschese V, Olcese R, Peroni DG, Pistorio A, Salmaso C, Silvestri M, Zicari AM PMID: 32914947 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - September 12, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

The show must go on. The impacts of SARS-CoV-2 pandemic on cutaneous allergology and patch testing.
Authors: Alpalhão M, Filipe P PMID: 32729314 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - July 31, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Association between the density and type of trees around urban schools and exhaled nitric oxide levels in schoolchildren.
Authors: Paciência I, Cavaleiro Rufo J, Ribeiro AI, Mendes FC, Farraia M, Silva D, Delgado L, Moreira A Abstract Summary: Greenspaces in school's neighbourhood represent an important environment to promote healthy development. The aim of this study was to assess the association between the density and type of trees around schools and exhaled nitric oxide (NO) levels in schoolchildren. Data on 845 children from 20 primary schools in Porto was analysed. Airway inflammation was assessed by measuring exhaled NO level. The density and type of trees were quantified within a 500 m buffer around schools. Associations...
Source: European Annals of Allergy and Clinical Immunology - July 31, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Speculations on red meat allergy due to á-Gal; its connection to coronary artery disease, suggested dietary guidance and allergy testing.
Speculations on red meat allergy due to á-Gal; its connection to coronary artery disease, suggested dietary guidance and allergy testing. Eur Ann Allergy Clin Immunol. 2020 Jul 30;: Authors: Pitsios C, Dimitriou A, Vassilopoulou E PMID: 32729316 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - July 31, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Drug use and abuse and the risk of adverse events in soccer players: results from a survey in Italian second league players.
Conclusions. This study shows that drug misuse/abuse in soccer is a real matter of debate, especially with regards to NSAIDs, exposing athletes to predictable and/or unpredictable risks for their health. PMID: 32729317 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - July 31, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Delayed corticosteroid hypersensitivity: a clinical management proposal.
Conclusions. Although the lack of standardization, the allergy workup proves useful to differentiate patients sensitized to one or few molecules from polysensitized and to identify the culprit drugs. Intradermal and challenge test are necessary to complete the diagnostic workup. The results suggest the possibility of a different management of patients. Patients of pattern one can be only patch tested with a limited series of CS belonging to the 3 groups. They don't need an extensive exclusion of steroids use. The pattern 2 and 3 must be submitted instead to a complete allergological individual evaluation to identify altern...
Source: European Annals of Allergy and Clinical Immunology - July 31, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

When to stop biologicals. Severe asthma exacerbation after mepolizumab discontinuation
Authors: Bagnasco D, Aloè T, Sclifò F, Ferrantino MG, Marugo F, Arcadipane F, Manfredi A, Canonica GW, Passalacqua G PMID: 31081606 [PubMed - indexed for MEDLINE] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - July 19, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Bet v 1 sensitization modulates allergenic molecular immune response.
Conclusions The present study demonstrates that Bet v 1 sensitization may significantly affect the sensitization pattern in children living in Genoa, a Mediterranean city located in a birch-free area. PMID: 30246512 [PubMed - indexed for MEDLINE] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - July 14, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Interference of Dermatophagoides pteronyssinus sensitization in grass pollen allergy.
Authors: López-Freire S, Méndez-Brea P, González-Fernández T, Gude F, Vidal C PMID: 32549528 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 20, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Biological and clinical significance of T helper 17 cell deficiency: insight into monogenic defects.
Authors: Anka AU, Abdullahi IN, Umar K, Mohammed Bello Z, Mohammed M, Gachpaz Sarkhiz S, Abubakar Kaoje N, Alsabbagh M, Kamali AN, Azizi G PMID: 32549544 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 20, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Anaphylaxis.
Authors: Bilò MB, Martini M, Tontini C, Corsi A, Antonicelli L PMID: 32550734 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 20, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Which skin prick test wheal size detects true allergy to Salsola kali?
Authors: Mona A, Edin J, Nermina A PMID: 32551465 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 20, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Hymenoptera venom immunotherapy, re-sting reactions, severity, effective.
Authors: Mesquita AM, Carneiro-Leão L, Amaral L, Coimbra A PMID: 32548996 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 19, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

IgG from atopic individuals can mediate non-atopic infant thymic and adult peripheral CD8 + TC2 skewing without influence on TC17 or TC22 cells.
Authors: Rodrigues de Sousa T, da Ressureição Sgnotto F, Oliveira Fagundes B, Souza Santos L, da Silva Duarte AJ, Russo Victor J PMID: 32548997 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 19, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Cypress pollen allergy in Milan: the story of an ongoing growth.
Authors: Asero R, Ceriotti V, Bonini M PMID: 32500980 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 7, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Omalizumab is effective in patients with chronic spontaneous urticaria plus multiple chronic inducible urticaria.
Authors: Skander D, Allenova A, Maurer M, Kolkhir P PMID: 32496030 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 6, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Assessment of IgE- and cell-mediated immunity in pediatric patients with eosinophilic esophagitis.
Authors: Yousefi A, Nasehi S, Arshi S, Nabavi M, Bemanian MH, Shokri S, Seif F, Khoshmirsafa M, Saeedi Y, Rajabian B, Mahjoub F, Sadeghian M, Talachian E, Fallahpour M PMID: 32496031 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - June 6, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Primary immunodeficiency disorders in children with Non-Cystic Fibrosis Bronchiectasis.
Conclusions.PID accounted for about 40% of NCFB. Early diagnosis/appropriate treatment have impact on clinical course of a PID patient. Thus, follow-up in also immunology clinics should be a routine for patients who experience pneumonia in the first year of their lives and those with NCFB. Most patients with NCFB (84.28%) had their first pulmonary infection within the first year of their lives. PMID: 32372587 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Subcutaneous and sublingual allergen-specific immunotherapy: a tale of two routes.
This article reviewed the available literature, including a large number of randomized controlled trials, meta-analyses, and real-life studies as well, on the outcomes of SCIT and SLIT concerning the treatment critical issues of the two routes, that are efficacy, safety, cost-effectiveness, and compliance to treatment. The efficacy of SCIT and SLIT is similar in respiratory allergy, providing, based on the induction of typical changes in the immunologic response, an early control of symptoms that steadily increases during the treatment and its efficacy lasts after the recommended duration of three years. Such results are t...
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Economic burden of severe asthma in Turkey: a cost of illness study from payer perspective.
Conclusions.In conclusion, our findings indicate that managing patients with severe asthma pose a considerable burden to health economics in Turkey, with medications as the main cost driver. PMID: 32372589 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Pediatric urticaria in the Emergency Department: epidemiological characteristics and predictive factors for its persistence in children.
Conclusions.The AU etiology identified by history in the ED may be a significant predictor of persistence after a first attack of AU. PMID: 32372590 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Successful desensitization procedure to lenalidomide in a patient with delayed hypersensitivity confirmed with a positive LTT.
Authors: Lazzarato I, Gonzalez-Muñoz M, Heredia R, Castellar PharmG FR, López de la Guía A, Cabañas R, Fiandor A, Dominguez-Ortega J PMID: 32374557 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Anxiety/depression and impaired asthma control in adolescents. Is an increased basal cholinergic tone a possible link ?
Authors: Liccardi G, Calzetta L, Milanese M, Bilò MB, Liccardi MV, Matera MG, Baiardini I, Rogliani P PMID: 32374558 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Unmet needs and relationship between general practitioners (GPs) and allergists living in Campania region (southern Italy).
Authors: Liccardi G, Calzetta L, Berra A, Caiazzo R, Califano F, Ciccarelli A, Cutajar M, D'Amato M, De Bartolomeis F, Dello Iacono I, Gargano D, Lo Schiavo M, Madonna F, Maniscalco M, Milanese M, Montera C, Narducci R, Papa G, Pedicini A, Sabatino G, Sacerdoti C, Savoia A, Stanziola A, Bilò MB, Rogliani P PMID: 32374559 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Diagnostic dilemmas of Titanium hypersensitivity in patients with medical implants: a case series.
Authors: Heitmiller K, Innes M, Zollo V, Sansur C, Goldner R, Powell D, Gaspari AA PMID: 32378396 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Omalizumab re-treatment rates in chronic spontaneous urticaria.
Authors: Khan S, Sholtysek S PMID: 32378397 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Chronic spontaneous urticaria treated with Omalizumab: what differentiates early from late responders?
Authors: Asero R PMID: 32378398 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 8, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Evaluation of two commercial peach extracts for skin prick testing in the diagnosis of hypersensitivity to lipid transfer protein. A multicenter study.
Authors: Asero R, Aruanno A, Bresciani M, Brusca I, Carollo M, Cecchi L, Cortellini G, Deleonardi G, Farsi A, Ferrarini E, Gabrielli G, Ingrassia A, Mauro M, Murzilli F, Nucera E, Onida R, Pastorello EA, Pinter E, Rizzi A, Russello M, Sacerdoti C, Scala G, Villalta D, Zampogna S, Amato S Abstract Summary: The clinical usefulness of two commercial peach extracts for SPT (by Lofarma SpA and ALK-Abellò, respectively) was compared in a multicenter study carried out in Italy. Peach allergic patients were tested with the two extracts in parallel and underwent the detection of IgE specific for all three peach aller...
Source: European Annals of Allergy and Clinical Immunology - May 1, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Characteristics of patients with C1 esterase inhibitor deficiency: a single center study.
Authors: Aytekin ES, Cagdas D, Tan C Abstract Summary: Hereditary angioedema (HAE) is a primary complement factor deficiency, characterized by recurrent submucosal/subcutaneous swelling episodes. SERPING1 gene defects encoding C1 esterase inhibitor (C1INH) are responsible from the disease. Fifteen patients with HAE are retrospectively evaluated in this study. All patients (n=15) had HAE type I, 13 were from the same family, other two from two different families. Median age at onset of symptoms was 7 years (2-20); median age on diagnosis, 12 (0,5-41) and median delay in diagnosis, 3 years (0-33). Clinical symptoms w...
Source: European Annals of Allergy and Clinical Immunology - May 1, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Allergic sensitization profiles among the foreign-born population in the north of Madrid.
Conclusions. Allergic sensitization in the foreign-born population was similar to that of the autochthonous population although differences between the groups were identified. PMID: 32338476 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 28, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

The role of allergoids in allergen immunotherapy: from injective to sublingual route.
Authors: Compalati E, Incorvaia C, Cavaliere C, Masieri S, Gargiulo A, Mistrello G, Frati F Abstract Summary: SummaryAllergen immunotherapy (AIT) is aimed at inducing tolerance to allergens, such as pollens, dust mites or moulds, by administering increasing amounts of the causative allergen through subcutaneous or sublingual route. The evidence of efficacy of AIT is high, but the issue of safety, especially for the subcutaneous route, must be taken into account. The search for safer AIT products aimed at reducing the allergenicity, and thus adverse reactions, while maintaining the immunogenicity, that is essential ...
Source: European Annals of Allergy and Clinical Immunology - April 28, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Clinical trial to assess tolerability and subrogate efficacy effects of an abbreviated schedule with house dust mites mixture subcutaneous immunotherapy.
Conclusions.SCIT with house dust mixture of ROXALL Medicina España S.A. seems to have an acceptable tolerability profile, induces blocking IgG and decreases skin reactivity. PMID: 32223886 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 1, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Asthma and COPD "overlap": a treatable trait or common several treatable-traits?
Asthma and COPD "overlap": a treatable trait or common several treatable-traits? Eur Ann Allergy Clin Immunol. 2020 Mar 19;: Authors: Gaspar Marques J, Lobato M, Leiria Pinto P, Neuparth N, Carreiro Martins P Abstract Summary: In the last years, disease classification of chronic respiratory diseases (CRD) has been vivaciously discussed and new concepts have been introduced, namely asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO). Controversially the GOLD consensus document of 2020 considered that we should no longer refer to ACO, as they constitute two different diseases that...
Source: European Annals of Allergy and Clinical Immunology - March 21, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Are currently available biomarkers useful to discriminate CSU patients not controlled by low dose omalizumab maintenance therapy?
Authors: Riccardo Asero J Abstract Summary: In patients with chronic spontaneous urticaria (CSU), low dose omalizumab maintenance therapy is effective in about one half of complete, fast responders to the drug. Omalizumab 150 mg/month was given as maintenance therapy to 21 patients with a history of severe CSU showing a complete (UAS7= 0) response to the dose of 300 mg/month. After 2 months of such regimen, patients were divided into controlled (n= 14; UAS7= 0) and not controlled (n= 7; UAS7> 10) and ESR, CRP, total IgE, and D-dimer were measured. The two groups did not differ in any of the biomarkers considered...
Source: European Annals of Allergy and Clinical Immunology - March 21, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Can concurrent lower gastrointestinal manifestations help the timely diagnosis of small intestinal bacterial overgrowth in CVID patients?
Conclusions.Regarding the high prevalence and non-specific manifestation of SIBO, it is suggested to consider concurrent symptoms in patients with CVID to manage the timely and precise diagnosis of SIBO. PMID: 32186350 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - March 19, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Omalizumab retreatment in patients with chronic spontaneous urticaria: a systematic review of published evidence.
Authors: Tonacci A, Nettis E, Asero R, Rossi O, Tontini C, Gangemi S Abstract Summary: A systematic review of the current literature on retreatment with omalizumab of patients with relapsing chronic spontaneous urticaria was performed. Published evidence shows that retreatment is safe and clinically effective, and that time to complete clinical response reduces as the number of retreatments increases. PMID: 32108461 [PubMed - as supplied by publisher] (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - March 1, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research