Quantity increase and functional affinity/avidity decrease of anti-Fc εRI and anti-IgE autoantibodies in chronic spontaneous urticaria
Conclusions. Both the quantity and avidity of anti-FcεRI and anti-IgE antibodies change over time, demonstrating that the CU-BAT is more suitable to diagnose aiCSU. In addition, the avidity of anti-FcεRI and anti-IgE antibodies do not correlate with CU-BAT and disease activity, suggesting that further factors independent of anti-FcεRI and anti-IgE autoantibodies contribute to aiCSU.PMID:38088172 | DOI:10.23822/EurAnnACI.1764-1489.320 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - December 13, 2023 Category: Allergy & Immunology Authors: L J örg N M üller-Wirth K Kammermann O Stalder W Pichle O Hausmann Source Type: research

Delayed postoperative reactions to metamizole: a diagnostic challenge
Conclusions. This study demonstrated that for a correct diagnosis a high degree of suspicion about possible delayed hypersensitivity drug reactions to metamizole in the postoperative setting is needed. In the investigation, provocation test with metamizole was decisive for diagnostic confirmation.PMID:38054601 | DOI:10.23822/EurAnnACI.1764-1489.317 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - December 6, 2023 Category: Allergy & Immunology Authors: A Lopes M Paulino A Sp ínola Santos E Pedro M Branco Ferreira Source Type: research

Probiotics, prebiotics and food allergy
Conclusions. The potential of probiotics to be used as therapeutic adjuvants in CMA and peanut OI is promising. However, there is inconsistency regarding the type of probiotic, the dose and duration of supplementation. Further studies are needed to clarify the role of probiotics and prebiotics in FA.PMID:38054607 | DOI:10.23822/EurAnnACI.1764-1489.319 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - December 6, 2023 Category: Allergy & Immunology Authors: J F Ribeiro C Pedrosa Source Type: research