Quantity increase and functional affinity/avidity decrease of anti-Fc εRI and anti-IgE autoantibodies in chronic spontaneous urticaria

Conclusions. Both the quantity and avidity of anti-FcεRI and anti-IgE antibodies change over time, demonstrating that the CU-BAT is more suitable to diagnose aiCSU. In addition, the avidity of anti-FcεRI and anti-IgE antibodies do not correlate with CU-BAT and disease activity, suggesting that further factors independent of anti-FcεRI and anti-IgE autoantibodies contribute to aiCSU.PMID:38088172 | DOI:10.23822/EurAnnACI.1764-1489.320

Source: European Annals of Allergy and Clinical Immunology - December 13, 2023 Category: Allergy & Immunology Authors: L J örg N M üller-Wirth K Kammermann O Stalder W Pichle O Hausmann Source Type: research