Clavulanic acid sensitization seems more involved in cutaneous than systemic reactions in amoxicilline-clavulanate drug reactions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.329. Online ahead of print.ABSTRACTBLs allergy is considered a major health issue, as BLs are the most frequently involved in drug allergic reactions. Amoxicillin (AX) is the most frequently involved drug in sensitization among all BLs. AX is commercialized alone or combined to clavulanic acid (CLA) in order to increase the antibiotic spectrum. The growing prescriptions of AX-CLA formulations contributed to increase the role of CLA as an allergy inducer. At present, little is known about the clinical characteristics of hypersensitivity reactions t...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: F Rivolta C Cappelletti A Sangalli A Fasiello V Longoni V Pravettoni Source Type: research

Why is Pet (cat/dog) allergen immunotherapy (ait) such a controversial topic? current perspectives and future directions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.330. Online ahead of print.ABSTRACTDogs and cats are the most common pets worldwide. In Italy, the prevalence of allergic sensitization to cats and dogs is 16% and 9% respectively. The limited standardization of allergenic extracts, especially for dogs, emphasizes the importance of Component Resolved Diagnosis (CRD) for accurate diagnosis and subsequent prescription of allergen immunotherapy (AIT). However, this low standardization is the main factor contributing to the unsatisfactory clinical efficacy of traditional AIT, AIT with modified allerge...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: G Liccardi M Martini M B Bil ò L Cecchi M Milanese L Brussino E Motta P Rogliani Source Type: research

A Survey on the association of seizure disorders with asthma and allergies in children
Conclusions. Febrile convulsion is associated with the .number of comorbid allergic diseases in children and the mother's number of allergic diseases is more related to idiopathic epilepsy in children than the father's.PMID:38347809 | DOI:10.23822/EurAnnACI.1764-1489.328 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: H Sadri A Madanipour N Toami M Bakhtiari H Montazerlotfelahi E Zahmatkesh A Zandifar M Tavakol Source Type: research

Clavulanic acid sensitization seems more involved in cutaneous than systemic reactions in amoxicilline-clavulanate drug reactions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.329. Online ahead of print.ABSTRACTBLs allergy is considered a major health issue, as BLs are the most frequently involved in drug allergic reactions. Amoxicillin (AX) is the most frequently involved drug in sensitization among all BLs. AX is commercialized alone or combined to clavulanic acid (CLA) in order to increase the antibiotic spectrum. The growing prescriptions of AX-CLA formulations contributed to increase the role of CLA as an allergy inducer. At present, little is known about the clinical characteristics of hypersensitivity reactions t...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: F Rivolta C Cappelletti A Sangalli A Fasiello V Longoni V Pravettoni Source Type: research

Why is Pet (cat/dog) allergen immunotherapy (ait) such a controversial topic? current perspectives and future directions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.330. Online ahead of print.ABSTRACTDogs and cats are the most common pets worldwide. In Italy, the prevalence of allergic sensitization to cats and dogs is 16% and 9% respectively. The limited standardization of allergenic extracts, especially for dogs, emphasizes the importance of Component Resolved Diagnosis (CRD) for accurate diagnosis and subsequent prescription of allergen immunotherapy (AIT). However, this low standardization is the main factor contributing to the unsatisfactory clinical efficacy of traditional AIT, AIT with modified allerge...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: G Liccardi M Martini M B Bil ò L Cecchi M Milanese L Brussino E Motta P Rogliani Source Type: research

A Survey on the association of seizure disorders with asthma and allergies in children
Conclusions. Febrile convulsion is associated with the .number of comorbid allergic diseases in children and the mother's number of allergic diseases is more related to idiopathic epilepsy in children than the father's.PMID:38347809 | DOI:10.23822/EurAnnACI.1764-1489.328 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: H Sadri A Madanipour N Toami M Bakhtiari H Montazerlotfelahi E Zahmatkesh A Zandifar M Tavakol Source Type: research

Clavulanic acid sensitization seems more involved in cutaneous than systemic reactions in amoxicilline-clavulanate drug reactions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.329. Online ahead of print.ABSTRACTBLs allergy is considered a major health issue, as BLs are the most frequently involved in drug allergic reactions. Amoxicillin (AX) is the most frequently involved drug in sensitization among all BLs. AX is commercialized alone or combined to clavulanic acid (CLA) in order to increase the antibiotic spectrum. The growing prescriptions of AX-CLA formulations contributed to increase the role of CLA as an allergy inducer. At present, little is known about the clinical characteristics of hypersensitivity reactions t...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: F Rivolta C Cappelletti A Sangalli A Fasiello V Longoni V Pravettoni Source Type: research

Why is Pet (cat/dog) allergen immunotherapy (ait) such a controversial topic? current perspectives and future directions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.330. Online ahead of print.ABSTRACTDogs and cats are the most common pets worldwide. In Italy, the prevalence of allergic sensitization to cats and dogs is 16% and 9% respectively. The limited standardization of allergenic extracts, especially for dogs, emphasizes the importance of Component Resolved Diagnosis (CRD) for accurate diagnosis and subsequent prescription of allergen immunotherapy (AIT). However, this low standardization is the main factor contributing to the unsatisfactory clinical efficacy of traditional AIT, AIT with modified allerge...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: G Liccardi M Martini M B Bil ò L Cecchi M Milanese L Brussino E Motta P Rogliani Source Type: research

A Survey on the association of seizure disorders with asthma and allergies in children
Conclusions. Febrile convulsion is associated with the .number of comorbid allergic diseases in children and the mother's number of allergic diseases is more related to idiopathic epilepsy in children than the father's.PMID:38347809 | DOI:10.23822/EurAnnACI.1764-1489.328 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: H Sadri A Madanipour N Toami M Bakhtiari H Montazerlotfelahi E Zahmatkesh A Zandifar M Tavakol Source Type: research

Clavulanic acid sensitization seems more involved in cutaneous than systemic reactions in amoxicilline-clavulanate drug reactions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.329. Online ahead of print.ABSTRACTBLs allergy is considered a major health issue, as BLs are the most frequently involved in drug allergic reactions. Amoxicillin (AX) is the most frequently involved drug in sensitization among all BLs. AX is commercialized alone or combined to clavulanic acid (CLA) in order to increase the antibiotic spectrum. The growing prescriptions of AX-CLA formulations contributed to increase the role of CLA as an allergy inducer. At present, little is known about the clinical characteristics of hypersensitivity reactions t...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: F Rivolta C Cappelletti A Sangalli A Fasiello V Longoni V Pravettoni Source Type: research

Why is Pet (cat/dog) allergen immunotherapy (ait) such a controversial topic? current perspectives and future directions
Eur Ann Allergy Clin Immunol. 2024 Feb 13. doi: 10.23822/EurAnnACI.1764-1489.330. Online ahead of print.ABSTRACTDogs and cats are the most common pets worldwide. In Italy, the prevalence of allergic sensitization to cats and dogs is 16% and 9% respectively. The limited standardization of allergenic extracts, especially for dogs, emphasizes the importance of Component Resolved Diagnosis (CRD) for accurate diagnosis and subsequent prescription of allergen immunotherapy (AIT). However, this low standardization is the main factor contributing to the unsatisfactory clinical efficacy of traditional AIT, AIT with modified allerge...
Source: European Annals of Allergy and Clinical Immunology - February 13, 2024 Category: Allergy & Immunology Authors: G Liccardi M Martini M B Bil ò L Cecchi M Milanese L Brussino E Motta P Rogliani Source Type: research

Local allergic rhinitis in children: identification and characterization in a specialty outpatient clinic
Conclusions. This study represents the first investigation of LAR in child and adolescent subjects in Latin America, contributing significantly to the understanding of its prevalence and characteristics in this geographic area. Among a subgroup of patients lacking systemic sensitization submitted to NAC, 40% (10/25) demonstrated a positive NAC with Dermatophagoides pteronyssinus and Blomia tropicalis, warranting their reclassification to LAR. NAC with multiple allergens has been proven safe and viable in pediatric populations, affirming its critical role in the accurate diagnosis of LAR.PMID:38258826 | DOI:10.23822/EurAnnA...
Source: European Annals of Allergy and Clinical Immunology - January 23, 2024 Category: Allergy & Immunology Authors: F Y Matsumoto T R Tranquillini Gon çalves D Sol é G F Wandalsen Source Type: research

Expression of IL-17RA in Innate Cells of Patients with Common Variable Immunodeficiency (CVID) and its Clinical Implications
Conclusions. The study suggests that despite previous reports of reduced circulating Th17 cells and IL-17 levels in CVID patients, IL-17RA expression in innate cells may be elevated, potentially indicating altered IL-17 signaling. This heightened IL-17RA expression could contribute to a persistent pro-inflammatory state, possibly due to microbial translocation or other inflammatory factors. The association of IL-17RA expression with gastrointestinal microbial colonization and its correlation with fecal calprotectin underscores the complexity of IL-17RA's role in CVID pathophysiology. Further research in larger cohorts coul...
Source: European Annals of Allergy and Clinical Immunology - January 23, 2024 Category: Allergy & Immunology Authors: P Botelho Alves H Pires Pereira J Costa Carvalho I Nunes A Todo-Bom E Faria F Regateiro A Paiva Source Type: research

Health-related Quality of Life in Hymenoptera Venom Allergy: Validation of the Italian version of the Vespid Allergy Quality of Life Questionnaire (VQLQ-i)
Eur Ann Allergy Clin Immunol. 2024 Jan 18. doi: 10.23822/EurAnnACI.1764-1489.325. Online ahead of print.NO ABSTRACTPMID:38235503 | DOI:10.23822/EurAnnACI.1764-1489.325 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - January 18, 2024 Category: Allergy & Immunology Authors: M Mauro D Bignardi I Baiardini P Bonadonna M C Braschi F Emiliani L Guerra S Liberati F Olivieri V Pravettoni D Preziosi E Ridolo F Rivolta M Martini M B Bil ò Source Type: research

Obstructive Sleep Apnea: a risk for uncontrolled and more severe asthma in adults that we should keep an eye on
Conclusions. It is crucial to actively investigate OSA, especially in patients with uncontrolled and more severe forms of asthma.PMID:38223952 | DOI:10.23822/EurAnnACI.1764-1489.324 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - January 15, 2024 Category: Allergy & Immunology Authors: G Martins Dos Santos P Sim ão Coelho J Gaspar Marques S Serranho S Santos A Brito P Carreiro Martins P Leiria Pinto Source Type: research