Arterial Blood Gas Analysis in Patients with Stridor, and the Impact of Emergency Tracheostomy on It: A Tertiary Care Center Experience
AbstractComparative evaluation of arterial blood gas in patients with stridor, before and after emergency tracheostomy. The present prospective study was conducted in tertiary care Centre from February 2022 to June 2023 on 42 patients who presented with stridor and underwent emergency tracheostomy in our department. After proper history taking and clinical examination, nonsurgical cause of stridor was ruled out. Patients were then classified on the basis of location of cause of stridor (whether oropharyngeal, hypo-pharyngeal, supra-glottic, glottic or sub-glottic). Immediately an arterial blood gas (ABG) analysis was done,...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - January 17, 2024 Category: ENT & OMF Source Type: research
Genetically predicted circulating levels of cytokines and the risk of oral cavity and pharyngeal cancer: a bidirectional mendelian-randomization study
Conclusion: Our study systematically assessed the association between inflammatory cytokines and the risk of OCPC. We identified two upstream regulatory factors (IL-7 and CCL3) and one downstream effector factor (IL-4) that were associated with OCPC, offering potential avenues for the development of novel treatments. (Source: Frontiers in Genetics)
Source: Frontiers in Genetics - January 11, 2024 Category: Genetics & Stem Cells Source Type: research
Impact of Presarcopenic Dysphagia on 1-Year Mortality After Videofluoroscopic Swallowing Study in Patients with Cancer
AbstractSarcopenic dysphagia is the term for swallowing difficulty associated with loss of mass, strength, and physical performance, which leads to increased pharyngeal residues. Unlike sarcopenia, presarcopenia is characterized by low muscle mass without decreased muscle strength or physical performance and can develop into dysphagia due to low skeletal muscle mass. This retrospective study investigated the impact of presarcopenic dysphagia (PSD) on 1-year mortality in patients with cancer and dysphagia who underwent a videofluoroscopic swallowing study (VFSS). An operational definition of PSD based on presarcopenia and p...
Source: Dysphagia - January 9, 2024 Category: Speech-Language Pathology Source Type: research
Analysis of swallowing and voice-related quality of life in patients after supracricoid partial laryngectomy
ConclusionSCPL provides patients with satisfactory swallowing and voice function. The patients in this study were satisfied with their quality of life in terms of swallowing and voice. SCPL can be used as a surgical method to preserve laryngeal function in patients with laryngeal cancer. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 6, 2024 Category: ENT & OMF Source Type: research
Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century
Conclusions5-year survival reached about 65% for all HN cancers, except for hypopharyngeal cancer (30%). Human papilloma virus infection is becoming a dominant risk factor for the rapidly increasing oropharyngeal cancer, the prevention of which needs to emphasize oral sex as a route of infection. (Source: Cancer Medicine)
Source: Cancer Medicine - January 2, 2024 Category: Cancer & Oncology Authors: Frantisek Zitricky,
Anni I. Koskinen,
Otto Hemminki,
Asta F örsti,
Akseli Hemminki,
Kari Hemminki Tags: RESEARCH ARTICLE Source Type: research
Risk of Parkinson's disease-related death in cancer survivors: A population-based study in Japan
CONCLUSIONS: Patients with cancer are at a high risk of PD-related death; particularly, mouth-to-stomach cancers and potentially obstructing medication for PD are attributable to a high mortality risk. Careful management, including adequate PD treatment, would benefit cancer survivors with PD and reduce the risk of PD-related death.PMID:38147694 | DOI:10.1016/j.parkreldis.2023.105966 (Source: Cancer Control)
Source: Cancer Control - December 26, 2023 Category: Cancer & Oncology Authors: Eri Hayano Yasufumi Gon Yasuyoshi Kimura Ling Zha Toshitaka Morishima Yuko Ohno Hideki Mochizuki Tomotaka Sobue Isao Miyashiro Source Type: research
Validation of the DIGEST-FEES as a Global Outcome Measure for Pharyngeal Dysphagia in Parkinson ’s Disease
The objective of this study was, therefore, to investigate the validity of the DIGEST-FEES in patients with PD. Content validity was evaluated with a modified Delphi expert survey. Subsequently, 66 FEES videos in PD patients were scored with the DIGEST-FEES. Criterion validity was determined using Spearman's correlation coefficient between the DIGEST-FEES and the Penetration-Aspiration Scale (PAS), the Yale-Residue-Rating-Scale, the Functional-Oral-Intake-Scale (FOIS), and the swallowing-related Unified-Parkinson-Disease-Rating-Scale (UPDRS) items. Inter-rater reliability was determined using 10 randomly selected FEES-vide...
Source: Dysphagia - December 22, 2023 Category: Speech-Language Pathology Source Type: research
Accurate and robust auto-segmentation of head and neck organ-at-risks based on a novel CNN fine-tuning workflow
CONCLUSION: The delineations of commercial AI software need to be carefully reviewed, and localized further training is necessary for clinical practice. The proposed fine-tuning workflow could be feasibly adopted to implement an accurate and robust auto-segmentation model by using local datasets and external public datasets.PMID:38128058 | DOI:10.1002/acm2.14248 (Source: Health Physics)
Source: Health Physics - December 21, 2023 Category: Physics Authors: Shunyao Luan Kun Wu Yuan Wu Benpeng Zhu Wei Wei Xudong Xue Source Type: research
Accurate and robust auto-segmentation of head and neck organ-at-risks based on a novel CNN fine-tuning workflow
CONCLUSION: The delineations of commercial AI software need to be carefully reviewed, and localized further training is necessary for clinical practice. The proposed fine-tuning workflow could be feasibly adopted to implement an accurate and robust auto-segmentation model by using local datasets and external public datasets.PMID:38128058 | DOI:10.1002/acm2.14248 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - December 21, 2023 Category: Physics Authors: Shunyao Luan Kun Wu Yuan Wu Benpeng Zhu Wei Wei Xudong Xue Source Type: research
Alveolar bone loss and tooth loss contribute to increase in cancer mortality among older patients
CONCLUSION: Our results indicate that older patients suffering from tooth loss or alveolar bone loss are at increased risks of cancer mortality, especially for total cancer and LOP cancer.PMID:38114973 | DOI:10.1186/s12903-023-03543-5 (Source: Cancer Control)
Source: Cancer Control - December 20, 2023 Category: Cancer & Oncology Authors: Yifeng Qian Binxin Cai Fangfang Chi Chunxia Yao Lei Zhang Lei Qi Yonggen Jiang Xudong Wang Source Type: research
Preoperative sleep-disordered breathing and craniofacial abnormalities are risk factors for postoperative sleep-disordered breathing in patients undergoing skin-flap oropharyngeal reconstruction surgery for oral cavity cancer: a prospective case-control study
CONCLUSIONS: Oropharyngeal reconstruction surgery worsens sleep-disordered breathing in some patients with craniofacial and surgical risk factors.TRIAL REGISTRATION: UMIN Clinical Trial Registry (UMIN000036260, March 22, 2019), https://rctportal.niph.go.jp/s/detail/um?trial_id=UMIN000036260.PMID:38110600 | DOI:10.1007/s11325-023-02962-6 (Source: Sleep and Breathing)
Source: Sleep and Breathing - December 19, 2023 Category: Sleep Medicine Authors: Fumihiro Yoshikawa Natsuko Nozaki-Taguchi Ayumi Yamamoto Nozomi Tanaka Aika Tanzawa Katsuhiro Uzawa Shiroh Isono Source Type: research
Cancer mortality and premature deaths among hairdressers in Brazil
CONCLUSIONS: Our results suggest that Brazilian female hairdressers are more likely to die from several cancers, with potential consequences on premature deaths. Causal associations to occupational risks, such as exposure to chemicals, should be investigated by observational epidemiologic studies. Meanwhile, it is important to promote public policies, regulations, and Occupational Safety and Health (OSH) strategies to protect hairdressers' health, mitigate occupational risks, and ensure safe workplaces.PMID:38113991 | DOI:10.1016/j.envres.2023.117942 (Source: Environmental Research)
Source: Environmental Research - December 19, 2023 Category: Environmental Health Authors: Rafael Buralli Adeylson Ribeiro Cleber Cremonese Paolo Vineis Armando Meyer Source Type: research
Preoperative sleep-disordered breathing and craniofacial abnormalities are risk factors for postoperative sleep-disordered breathing in patients undergoing skin-flap oropharyngeal reconstruction surgery for oral cavity cancer: a prospective case-control study
CONCLUSIONS: Oropharyngeal reconstruction surgery worsens sleep-disordered breathing in some patients with craniofacial and surgical risk factors.TRIAL REGISTRATION: UMIN Clinical Trial Registry (UMIN000036260, March 22, 2019), https://rctportal.niph.go.jp/s/detail/um?trial_id=UMIN000036260.PMID:38110600 | DOI:10.1007/s11325-023-02962-6 (Source: Sleep and Breathing)
Source: Sleep and Breathing - December 19, 2023 Category: Sleep Medicine Authors: Fumihiro Yoshikawa Natsuko Nozaki-Taguchi Ayumi Yamamoto Nozomi Tanaka Aika Tanzawa Katsuhiro Uzawa Shiroh Isono Source Type: research
Comparison of global decolonization efficacy with mupirocin nasal drop and chlorhexidine mouthwash in acute leukemia patients: randomized clinical trial
ConclusionGlobal decolonization with mupirocin nasal drop not only eradicates both nasal and pharynx microorganisms, but also reduces antibiotic requirement and frequency of fever in patients with acute leukemia.The protocol of the present study was approved on December 2016 (registry number: IRCT20160310026998N6). (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 19, 2023 Category: Cancer & Oncology Source Type: research
Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy
Head and neck cancer (HNC) is the sixth most common type of cancer, with more than half a million new cases annually. This review focuses on the role of oral dysbiosis and HPV infection in HNCs, presenting the involved taxons, molecular effectors and pathways, as well as the HPV-associated particularities of genetic and epigenetic changes and of the tumor microenvironment occurred in different stages of tumor development. Oral dysbiosis is associated with the evolution of HNCs, through multiple mechanisms such as inflammation, genotoxins release, modulation of the innate and acquired immune response, carcinogens and antica...
Source: Frontiers in Oncology - December 18, 2023 Category: Cancer & Oncology Source Type: research
