Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer
Conditions: Oropharyngeal Squamous Cell Carcinoma; Human Papillomavirus Infection Interventions: Genetic: Pre-Radiation Dental Evaluation/Sample Collection; Other: Pre-Study Visit; Genetic: Oral Medicine Consultation Visit/Sample Collection Sponsors: Wake Forest University Health Sciences; InnoTech Precision Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
The effects of Phoniatric PREhabilitation in Head and Neck Cancer patients on Aspiration and Preservation of Swallowing (PREHAPS): study protocol of a monocentric prospective randomized interventional outcome-blinded trial
DiscussionPrehabilitation measures have already proven successful in other patient groups, e.g., transplant patients. In the field of head and neck oncology, interest in such concepts has increased significantly in recent years. However, usually, only subgroups, e.g., patients with swallowing problems after radiochemotherapy alone, are in focus. Our study aims to investigate the general benefit of prehabilitation with regard to swallowing function, which is so important for protection of aspiration and quality of life.Trial registrationGerman Clinical Trials RegisterDRKS00029676. International Clinical Trials Registry Pl...
Source: Trials - March 22, 2024 Category: Research Source Type: clinical trials
Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial
Conditions: Cancer of Head and Neck; Mucositis Oral; Pharyngeal Mucositis Intervention: Drug: Ketamine Topical Sponsor: Bhupesh Parashar, MD Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2022 Category: Research Source Type: clinical trials
The curative effects of shortwave diathermy on treating Novel coronavirus (COVID-19) pneumonia: A structured summary of a study protocol for a randomised controlled trial
This study will be conducted in Tongji Hospital, Caidian, Wuhan, People ’s Republic of China.Intervention and comparatorThe experimental group will be given the nationally recommended standard medical treatment + ultra-short-wave diathermy treatment. Ultra-short-wave therapy treatment will be performed through application of ultra-short-wave therapy machine electrodes on the anterior and posterior parts of the trunk for 10 minutes, twice a day for 12 consecutive days. The comparator will be the control, not receiving ultra-short-wave therapy, and will be given only the nationally recommended standard medical treatment.Ma...
Source: Trials - July 2, 2020 Category: Research Source Type: clinical trials
Randomised controlled trial comparing efficacy and safety of high versus low Low-Molecular Weight Heparin dosages in hospitalized patients with severe COVID-19 pneumonia and coagulopathy not requiring invasive mechanical ventilation (COVID-19 HD): a structured summary of a study protocol
AbstractObjectivesTo assess whether high doses of Low Molecular Weight Heparin (LMWH) (i.e. Enoxaparin 70 IU/kg twice daily) compared to standard prophylactic dose (i.e., Enoxaparin 4000 IU once day), in hospitalized patients with COVID19 not requiring Invasive Mechanical Ventilation [IMV], are:more effective in preventing clinical worsening, defined as the occurrence of at least one of the following events, whichever comes first:DeathAcute Myocardial Infarction [AMI]Objectively confirmed, symptomatic arterial or venous thromboembolism [TE]Need of either:Continuous Positive Airway Pressure (Cpap) or Non-Invasive Ventilatio...
Source: Trials - June 25, 2020 Category: Research Source Type: clinical trials
