Fight Aging! Newsletter, December 4th 2023
This study produced a great deal of data that continues to be mined for insights into human aging and effects of calorie restriction in a long-lived species such as our own, to contrast with the sizable effects on health and longevity in short-lived species such as mice.
In particular, and the topic for today, cellular senescence and its role in degenerative aging has garnered far greater interest in the research community in the years since the CALERIE study took place. Thus in today's open access paper, scientists examine CALERIE study data to find evidence for calorie restriction to reduce the burden of cellular ...
Source: Fight Aging! - December 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, January 4th 2021
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - January 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cancer Survivors Exhibit Greater Risk of New Cancers and Higher Mortality Due to those Cancers
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - December 29, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Symani Microsurgical System Cleared in Europe
Medical Microinstruments (MMI), a company based outside of Pisa, Italy, won the European CE Mark of approval for its Symani robotic surgical system. The product provides 7-20X scaling of hand movements, automatically removing tremors to allow for safe microsurgical and supermicrosurgical procedures. It is hoped that this impressive new device can help to improve how free-flap reconstructions, replantations, peripheral nerve repairs and lymphatic surgery are performed.
Surgeons operate on the Symani via its console that includes a built-in chair, manipulators, and a series of foot switches. The system relies on th...
Source: Medgadget - November 18, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Neurosurgery Orthopedic Surgery Plastic Surgery Vascular Surgery Source Type: blogs
Nasal Endoscopy for Urgent and Complex ED Cases
Fiberoptics and endoscopy have changed the way we treat patients in the emergency department. Endoscopes are relatively easy to use, and can aid your diagnosis and treatment plan. Endoscopy may be useful in urgent cases, such as epistaxis, nasal foreign bodies, and ear debridement. It may also be helpful when dealing with more complicated presentations and critically ill patients, such as those with Ludwig's angina, epiglottis, tracheostomies, or those who need intubation.Fiberoptic tools are not just for surgeons and consultants. The endoscope has many uses in the emergency department, and we have a few tips and tricks...
Source: The Procedural Pause - October 28, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
“Selfish” Gene Enhances Own Transmission at Expense of Organism’s Fertility
These glowing images of yeast (Schizosaccharomyces kambucha) reproductive cells show an example of a selfish gene at work. Here, the selfish gene boosts its chances of being passed to the next generation by producing both a toxin (stained cyan) and an antitoxin (stained magenta). Cells with a copy of the selfish gene are protected by the antitoxin, left and bottom ovals. Those without the selfish gene are destroyed by the toxin. Scientists suspect that selfish genes could be operating throughout many organisms’ genomes, possibly having a major impact on how genetic material is inherited over generations. Credit: Image co...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 21, 2017 Category: Research Authors: Kathryn Calkins Tags: Genetics DNA Evolutionary Biology Genes Source Type: blogs
Fight Aging! Newsletter, April 17th 2017
This study assessed the prevalence of grey hair in patients with coronary artery disease and whether it was an independent risk marker of disease.
This was a prospective, observational study which included 545 adult men who underwent multi-slice computed tomography (CT) coronary angiography for suspected coronary artery disease. Patients were divided into subgroups according to the presence or absence of coronary artery disease, and the amount of grey/white hair. The amount of grey hair was graded using the hair whitening score: 1 = pure black hair, 2 = black more than white, 3 = black equals white, 4 = white more t...
Source: Fight Aging! - April 16, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Medical Mispronunciations and Misspelled Words: The Definitive List.
Hearing medical mispronunciations and seeing misspelled words are an under appreciated joy of working in healthcare. Physicians often forget just how alien the language of medicine is to people who don't live it everyday. The best part about being a physician is not helping people recover from critical illness. The best part is not about listening and understanding with compassion and empathy. Nope, the best part about being a physician is hearing patients and other healthcare providers butcher the language of medicine and experiencing great entertainment in the process. Doctors c...
Source: The Happy Hospitalist - October 2, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs
Wingnuttery kills
Among the sexually transmitted infections, Human Papilloma Virus (HPV, to its friends) is among the least glamorous. Everyone knows syphilis and gonorrhea, but for some reason HPV doesn't share their celebrity. It should, because some strains of it cause a very common and highly unpleasant problem, genital warts -- or warts wherever people's parts happen to interact, and you can use your imagination. Other strains cause cancer -- cervical, genital, anal, oral and pharyngeal. In fact, HPV is basically the cause of cervical cancer.So it doesn't take a sodomite to see that a vaccine which is highly effective in preventing tra...
Source: Stayin' Alive - May 10, 2013 Category: Health Medicine and Bioethics Commentators Source Type: blogs
OralCDx Places Oral Cancer on Short List of Preventable Diseases
Oral Cancer Awareness Week: A Disease That is Rapidly Growing Among Women, Young People and Non-Smokers 4 billion mathematical operations per second used to analyze each of the 100,000 cells painlessly obtained from the mouth of one patient. Over 500,000 patients already tested by primary care physicians, ENTs and dentists. 50,000 precancerous abnormalities found. 2,000 lives saved. Oral cancer has met its match. Oral Cancer Awareness Week was created by people who saw the anguish that oral cancer can cause and refused to give up. This week is in memory of all those who have suffered and died from...
Source: Dental Technology Blog - April 16, 2013 Category: Dentists Source Type: blogs
Annual Report to the Nation on Cancer Trends: Cancer Deaths Continue to Fall, But We Can Do Better
This report comes out every year. It is a summation of what we know about the trends in incidence rates for the most common cancers in the United States among both men and women as well as the trends in death rates from those cancers that lead to the highest mortality in the general population as well as specific ethnic groups. It is in a real sense a report card on our progress, which in large part is good but in a number of cancers, not so good.
The good news is what we have come to expect: since the year 2000, the overall cancer death rates have continued to decline 1.8% per year in men, 1.4% in women and 0.6% per year ...
Source: Dr. Len's Cancer Blog - January 7, 2013 Category: Cancer Authors: Dr. Len Tags: Access to care Breast Cancer Cancer Care Cervical Cancer Colon Cancer Early detection Lung Cancer Other cancers Prevention Prostate Cancer Rectal Cancer Research Screening Tobacco Treatment Vaccines Source Type: blogs
