Impact of balloon laryngoplasty on management of acute subglottic stenosis
ConclusionWhen used for management of acute laryngeal stenosis, balloon laryngoplasty is associated with a high success rate, presenting lower morbidity than open surgery. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - July 14, 2018 Category: ENT & OMF Source Type: research

Effect of the temperature of nasal lavages on mucociliary clearance: a randomised controlled trial
AbstractBackgroundThe respiratory epithelium is mainly constituted by caliciform (produces mucus, responsible of keeping moisture and trapping particles) and ciliated cells (transports mucus into the pharynx, by the movement of multiple cilia). For centuries, nasal lavages have been used for different rhinosinusal conditions. Some studies suggest not only a direct effect on the mobilisation of secretions, but also an improvement in mucociliary clearance rates. To our knowledge, the impact of temperature in nasal lavages has been scarcely studied.Methodology/principalWe used the saccharin test —applying it in the infe...
Source: European Archives of Oto-Rhino-Laryngology - July 13, 2018 Category: ENT & OMF Source Type: research

What is a normal pharynx? A videofluoroscopic study of anatomy in older adults
This study presents quantitative pharyngeal anatomic features in healthy adults using videofluoroscopic study of swallowing (VFSS). This will help our understanding of the normal changes in swallowing that occur with age and illustrate what may constitute normal variation compared with abnormal swallow function.Methods138 mixed gender adults with no history of dysphagia were recruited and underwent a standardized VFSS protocol. Parameters including age, BMI, and gender were correlated with the presence of a cricopharyngeal bar, spinal changes and pharyngeal wall thickness at rest.Results46% of participants had notable spin...
Source: European Archives of Oto-Rhino-Laryngology - July 12, 2018 Category: ENT & OMF Source Type: research

TNF-alpha G/A308 polymorphism association with nasal polyposis in North part of Iran
AbstractNasal Polyposis (NP) is a complex multi-factorial disease; associated with several environmental, genetic and inflammatory factors. TNF-alpha is one of the major pro-inflammatory cytokines involved in NP pathogenesis. Some of the polymorphisms of this gene affect its expression. Therefore, the aim of this study was to evaluate the polymorphism of TNF-alpha G/A308 gene and its association with nasal polyposis in north part of Iran. In this case-control study, 60 patients with NP and 75 healthy individuals referred to Guilan University hospital were evaluated. After DNA extraction, RFLP-PCR was used to determine poly...
Source: European Archives of Oto-Rhino-Laryngology - July 12, 2018 Category: ENT & OMF Source Type: research

Differential expression of cyclooxygenase-2 and cyclin D1 in salivary gland tumors
AbstractPurposeSalivary gland tumors are complex and have a great histomorphological diversity; more than 30 histological subtypes are currently described and the study of proteins that help understand and differentiate these tumors is essential. We aimed to analyze the immunoexpression of cyclooxygenase-2 (COX-2) and cyclin D1 proteins in pleomorphic adenomas (PA), mucoepidermoid carcinomas (MEC) and adenoid cystic carcinomas (AdCC) of salivary glands.MethodsA total of 38 PA, 12 AdCC and 12 MEC underwent immunohistochemical study by the polymeric biotin-free technique. Immunopositive cells were analyzed semi-quantitativel...
Source: European Archives of Oto-Rhino-Laryngology - July 12, 2018 Category: ENT & OMF Source Type: research

Prognosis of septic cavernous sinus thrombosis remarkably improved: a case series of 12 patients and literature review
ConclusionsThe prognosis of CST nowadays is more favorable than previously described. Anticoagulation seems to be a safe addition to antibiotic and surgical treatment, at least in patients without central nervous system infection. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - July 11, 2018 Category: ENT & OMF Source Type: research

Leukocyte- and platelet-rich fibrin: a new graft material in endoscopic repair of spontaneous CSF leaks
ConclusionL-PRF was found to be a good adjunct material in endoscopic spontaneous CSF leaks repair. It helps in decreasing the number of layers needed for defect closure. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - July 7, 2018 Category: ENT & OMF Source Type: research

Analysis of dysphagia in advanced-stage head-and-neck cancer patients: impact on quality of life and development of a preventive swallowing treatment
AbstractObjectivesSwallowing and voice dysfunctions are common side effects following head-and-neck squamous-cell carcinoma (HNSCC) treatment. Our aim was to analyze the relationships between quality of life, swallowing, and phonatory problems in patients with an advanced-stage HNSCC and to prospectively evaluate the effects of a prophylactic swallowing program.MethodsFirst, we retrospectively studied 60 advanced HNSCC patients treated with exclusive or adjuvant radiotherapy/chemoradiotherapy (RT/CRT). Subjects were classified according to general and clinical –therapeutic features. Outcome measures included EORTC QL...
Source: European Archives of Oto-Rhino-Laryngology - July 5, 2018 Category: ENT & OMF Source Type: research

Cochlear implantation in children with CHARGE syndrome: a report of eight cases
ConclusionsThe constant presence of temporal bone anomalies in children with CS requires surgical expertise in performing non-standard approaches for safe and effective CI. Patients with progressive SNHL and normal cochlear nerves had satisfactory results with CI. Limited benefits have been observed in presence of CND. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - July 3, 2018 Category: ENT & OMF Source Type: research

Histogram analysis of apparent diffusion coefficient maps for differentiating malignant from benign parotid gland tumors
AbstractPurposeTo evaluate the diagnostic performance of histogram parameters derived from diffusion-weighted imaging (DWI) for differentiating malignant from benign parotid gland tumors compared with that of hotspot region of interest (ROI)-based apparent diffusion coefficient (ADC) measurement.MethodsOur study retrospectively enrolled 60 patients with parotid gland tumors who had undergone DWI scan for pre-treatment evaluation. ADC measurements were performed using hotspot ROI (ADCHS-ROI)-based and histogram-based approach. Histogram parameters included mean (ADCmean), median (ADCmedian), 10th (ADC10), 90th (ADC90) perce...
Source: European Archives of Oto-Rhino-Laryngology - July 2, 2018 Category: ENT & OMF Source Type: research

ENT audit and research in the era of trainee collaboratives
AbstractLarge surgical audits and research projects are complex and costly to deliver, but increasingly surgical trainees are delivering these projects within formal collaboratives and research networks. Surgical trainee collaboratives are now recognised as a valuable part of the research infrastructure, with many perceived benefits for both the trainees and the wider surgical speciality. In this article, we describe the activity of ENT trainee research collaboratives within the UK, and summarise how INTEGRATE, the UK National ENT Trainee Research Network, successfully delivered a national audit of epistaxis management. Th...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Reliability and validity of the Eating Assessment Tool-10 (Greek adaptation) in neurogenic and head and neck cancer-related oropharyngeal dysphagia
AbstractPurposeDysphagia is a symptom associated with significant morbidity and mortality, with profound impact on physical ability and quality of life. Many questionnaires have been used to assess patient-reported dysphagia, but issues related to developmental and measurement properties affect their wide applicability. The purpose of this study was to assess the validity and reliability of the Eating Assessment Tool-10 (EAT-10, Greek adaptation) in neurogenic and head and neck cancer-related dysphagia.MethodsThe study consisted of: item generation in the Greek language, internal consistency and reliability analysis, norma...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Is the modified cupulolith repositioning maneuver effective for treatment of persistent geotropic direction-changing positional nystagmus?
ConclusionOur findings indicate that mCuRM had no therapeutic benefit for a persistent geotropic DCPN and suggest that the pathophysiology of persistent geotropic DCPN is less likely to be a light debris attached to the cupula. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

De-mucosalized pharyngeal flap: a modified technique for selected cases of velopharyngeal insufficiency
ConclusionThe modified de-mucosalized, superiorly based pharyngeal flap technique ensured self-mucosal draping of the bed, thus it would enhance primary healing and decrease postoperative pain with the resultant early ambulation. We believe that the new modified technique could correct VPI, in addition to the improvement of patients ’ comfort and decrease the morbidity of the procedure. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

The lymphocyte-to-monocyte ratio as a prognostic indicator in head and neck cancer: a systematic review and meta-analysis
ConclusionsAn elevated LMR may be an indicator of favorable prognosis in HNC. However, our results should be interpreted with some degree of caution due to the retrospective nature of cohort studies. Further research with high-quality prospective studies is needed to confirm the effect of LMR in HNC prognosis. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Impact of residual frontal recess cells on frontal sinusitis after endoscopic sinus surgery
AbstractPurposeEndoscopic sinus surgery (ESS) is a well-established treatment for chronic rhinosinusitis (CRS). However, ESS for frontal sinusitis remains complicated and challenging. The aim of this study was to identify the relationship between residual frontal recess cells and primary ESS failure in the frontal sinus.MethodsWe prospectively collected information on 214 sides of 129 patients with CRS who underwent standard ESS from June 2010 to May 2011. To identify risk factors, we retrospectively analyzed clinical data and computed tomography (CT) images before and 3  months after surgery.ResultsThe posterior side...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Provox 2 ® and Provox Vega ® device life-time: a case-crossover study with multivariate analysis of possible influential factors and duration
AbstractIntroductionTracheoesophageal speech is considered the gold standard for rehabilitation following total laryngectomy. Current literature is limited and contradictory about the possible causes of device failure. The aim of the study is to compare the device life-time between the Provox 2 and Provox Vega and to examine possible related factors that influence their duration.MethodsRetrospective case-crossover study in 34 laryngectomized patients who had undergone tracheoesophageal voice rehabilitation using indwelling Provox 2 and Provox Vega voice prostheses between 2010 and 2016 in a tertiary care centre.ResultsA to...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Malleostapedotomy with the self-fixing and articulated titanium piston
ConclusionsThe malleostapedotomy procedure has become surgically less demanding over time by the technical improvements present in the nowadays available pistons. The design of the self-fixing and articulated titanium piston used in the present group of patients allows a safe and straight-forward malleostapedotomy procedure. Present hearing outcomes match with results presented in the literature. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Laser debulking or tracheotomy in airway management prior to total laryngectomy for T4a laryngeal cancer
ConclusionsA tracheotomy prior to a total laryngectomy is associated with decreased survival. We recommend laser debulking as the preferred treatment whenever management of an obstructive airway is required prior to a total laryngectomy. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Percutaneous bone-anchored hearing implant surgery: linear incision technique with tissue preservation versus linear incision technique with tissue reduction
ConclusionLITT-P has a significantly higher rate of skin thickening and LITT-R has a significantly higher proportion of adverse soft tissue reactions. Nevertheless, combined with the advantages of LITT-P described in other studies, this can be advocated as the preferred technique. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Comparison of narrow band imaging and the Storz Professional Image Enhancement System for detection of laryngeal and hypopharyngeal pathologies
AbstractObjectiveThe aim of this study was to compare narrow band imaging (NBI) endoscopy and Storz Professional Image Enhancement System (SPIES) in observing epithelial and/or subepithelial microvascular irregularities and pathologies.MethodsA total of 73 patients with laryngeal or hypopharyngeal lesions were investigated using high-definition NBI endoscopy preoperatively in local anesthesia and using SPIES system intraoperatively in general anesthesia from August 2016 to October 2017. Superficial vascular structures were classified preoperatively (NBI) and intraoperatively (SPIES) according to descriptive guidelines of v...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Patient-reported outcome: results of the multicenter German post-market study
AbstractPurposeUpper airway stimulation (UAS) is an alternative second-line treatment option for patients with obstructive sleep apnea (OSA). In our substudy of a previous multicentre study of patients implanted with UAS, we focused on patient-related outcomes like Epworth Sleepiness Scale (ESS), the Functional Outcomes of Sleep Questionnaire (FOSQ), snoring and personal satisfaction 6 and 12  months after the implantation.Methods60 patients, who were initially non-adherent to CPAP and implanted with UAS, were included in a prospective multicentre study. Data were collected preoperative, 6 and 12  months after im...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Proposal of a form for the collection of videolaryngostroboscopy basic findings
We present a form for the collection of basic laryngostroboscopic findings, which provides for the evaluation of the classical six parameters codified by Hirano (symmetry and periodicity of glottic vibration, glottic closure, profile of vocal fold edge, amplitude of vocal fold vibration, mucosal wave) and six other parameters which we have included in the form for an essential and complete laryngostroboscopic evaluation (supraglottic framework behaviour, seat of phonatory vibration, vocal fold morphology and motility, level of the vocal fold, stops of vocal fold mucosa vibration). This form was created in 2002 during the e...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

P1 cortical auditory evoked potential in children with unilateral or bilateral cochlear implants; implication for the timing of second cochlear implantation
AbstractObjectiveTo examine maturation of the central auditory pathway, using P1 cortical auditory evoked potential (CAEP), in children who had received unilateral or bilateral cochlear implantation (CI).Study designProspective study.SettingTertiary referral hospital.MethodsTwenty children who had received CI due to congenital, or prelingual, deafness participated in the study. Participants had received the 1st implant at a mean age of 3.4  ± 0.7 years; 16 had also received a 2nd CI for the contralateral ear, at a mean age of 11.1 ± 2.1 years. P1 CAEP was recorded while u...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Expression of cancer stem cell markers CD44, ALDH1 and p75NTR in actinic cheilitis and lip cancer
AbstractPurposeThe aim of this work was to evaluate the expression of the cancer stem cell (CSC) markers CD44, ALDH1 and p75NTR in the ultraviolet-induced lesions actinic cheilitis (AC) and lip squamous cell carcinoma (LSCC), and to correlate it with p53 expression.MethodsImmunohistochemistry was performed in 4 cases of normal lip (NL), 43 of AC and 20 of LSCC.ResultsAll cases were positive for CD44, showing a membranous staining without differences between the groups. ALDH1 showed cytoplasmic staining and it was invariable amongst the grades of epithelial dysplasia and between AC and LSCC. p75NTR presented membranous/cyto...
Source: European Archives of Oto-Rhino-Laryngology - June 7, 2018 Category: ENT & OMF Source Type: research

Olfactory bulbus volume and olfactory sulcus depth in migraine patients: an MRI evaluation
ConclusionOB volume values were lower in migraine patients. When osmophobia was present, the OB volume was lower than that of the non-osmophobia migraine patients. Olfactory function monitoring with olfactory tests and olfactory volume monitoring on MRI can be recommended for all migraine patients to diagnose olfactory dysfunction earlier, especially those with osmophobia. Because their OB volume values were detected as lower than those of the migraine patients without osmophobia, it may be thought that blood flow changes and osmophobia may affect the olfactory bulb volume shrinkage in migraine patients. (Source: European ...
Source: European Archives of Oto-Rhino-Laryngology - June 6, 2018 Category: ENT & OMF Source Type: research

Oncological and functional outcomes of transoral laser surgery for laryngeal carcinoma
AbstractIntroductionTransoral laser microsurgery (TLM) has become the standard approach for treatment of early-stage laryngeal carcinoma in most institutions due to their good oncological and functional results with few local complications. The purpose of this study was to analyze the oncological and functional results of TLM in the treatment of laryngeal tumors at our Hospital.Materials and methodsPatients with laryngeal squamous cell carcinoma (LSCC) treated from 1998 to 2013 with TLM with curative intention, and with a minimum follow-up of 24 months, were reviewed.Results203 patients with LSCC were included. 195 patient...
Source: European Archives of Oto-Rhino-Laryngology - June 5, 2018 Category: ENT & OMF Source Type: research

Improvement in minimal cross-sectional area and nasal-cavity volume occurs in different areas after septoplasty and radiofrequency therapy of inferior turbinates
AbstractPurposeSeptoplasty and radiofrequency therapy for inferior turbinate hypertrophy (RFIT) are common techniques used to improve nasal patency. Our aim was to compare nasal geometry and function using acoustic rhinometry and peak nasal inspiratory flow (PNIF) in three patients groups undergoing surgery for nasal obstruction, and to investigate if the improvement in minimal cross-sectional area (MCA) and nasal-cavity volume (NCV) occurred in different cavity areas in the groups. Finally, we evaluated the correlation between the objective measurements and the patients ’ assessment of nasal obstruction (SNO).Method...
Source: European Archives of Oto-Rhino-Laryngology - June 5, 2018 Category: ENT & OMF Source Type: research

Autophony of eyelid movement is not independent of eyeball movement
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 5, 2018 Category: ENT & OMF Source Type: research

Lamb larynx model for training in endoscopic and CO 2 laser-assisted surgeries for benign laryngotracheal obstructions
ConclusionsThe lamb model system does not pose ethical issues, and it is easy to obtain and to handle. It was used during an international training course for laryngotracheal stenosis by novice and advanced airway surgeons. It was unanimously judged as relevant and useful by the participants. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 4, 2018 Category: ENT & OMF Source Type: research

Orbital infections: a complete cycle 7-year audit and a management guideline
This article presents the outcomes of a 7-year complete cycle audit project and describes the development of the new local guideline on the management of orbital infections in our tertiary centre.Methods(1) A retrospective 5-year audit cycle on patients with orbital infections. (2) A review of available evidence on the management of orbital infections. (3) A new local multidisciplinary guideline on the management of orbital infections. (4) A retrospective 2-year second audit cycle to assess the clinical outcomes.ResultsVarious disciplines intersect in the management of orbital infections. Standardising the management of th...
Source: European Archives of Oto-Rhino-Laryngology - June 4, 2018 Category: ENT & OMF Source Type: research

Early effects of irradiation on laryngeal mucosa in a gastroesophageal reflux model: an experimental study
ConclusionIonizing radiation-induced inflammation may increase on previously inflammated area due to gastroesophageal reflux. Therefore, it may be helpful to investigate and treat the reflux in laryngeal cancer patients that will receive ionizing radiation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 4, 2018 Category: ENT & OMF Source Type: research

Parameters of skull vibration-induced nystagmus in normal subjects
ConclusionsHealthy subjects do not generally develop to NR upon vibratory stimulation and only 20% of the subjects studied here developed any kind of NR, this being a slow and inconsistent response of low frequency. The establishment of normal values contributes to improve the orientation in clinical practice in the pathological population and this opens possibilities for tackling more reliable studies in this population. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 1, 2018 Category: ENT & OMF Source Type: research

A low cost and stepwise training model for skull base repair using a suturing and knotting technique during endoscopic endonasal surgery
ConclusionsThis low cost and stepwise training model improved the suture and knot skills for skull base repair during endoscopic endonasal surgery. Experienced microneurosurgical neurosurgeons perform this technique more competent. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - June 1, 2018 Category: ENT & OMF Source Type: research

Chronic inflammatory demyelinating polyneuropathy: evaluation of the vestibular system with cervical and ocular vestibular evoked myogenic potentials
ConclusionsA specific diagnostic protocol including the caloric test, C-VEMPS, O-VEMPS, could be useful when employed for identifying vestibular damage in CIDP patients. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Synchronized roles of pannexin and connexin in nasal mucosal epithelia
ConclusionsConnexins participate in the generation of intercellular calcium waves, in which calcium-mediated signaling responses spread to contiguous cells through the gap junction formed by connexins to transmit calcium signaling throughout the airway epithelium. Pannexins in the nasal mucosa may contribute to not only ciliary beat modulation via ATP release, but also regulation of mucus blanket components via H2O efflux. The synchronized roles of pannexin and connexin may provide a new insight into effective mucociliary clearance systems in nasal mucosa. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Low inter-examiner agreement of the Friedman staging system indicating limited value in patient selection
ConclusionThe Friedman staging system demonstrated a low inter-examiner agreement, indicating that the system is an uncertain method for selecting patients for uvulopalatopharyngoplasty.Level of evidence2B. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Influence of MP 29-02 on ciliary beat frequency in human epithelial cells in vitro
AbstractPurposeMP 29-02, which contains fluticasone propionate and azelastine hydrochloride, is used as a topical nasal application for the treatment of seasonal and perennial allergic rhinitis. Although a multitude of data is available on the clinical symptom reduction and treatment safety of MP 29-02, the effect of MP 29-02 on ciliary beat frequency (CBF) has not been evaluated thus far.MethodsMP 29-02-containing solution was applied at concentrations of 2.5, 5, 10, and 20% to 14 healthy subjects, and nasal ciliated epithelial cells were then visualized using a phase-contrast microscope. CBF was measured after the applic...
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Reducing post-tonsillectomy haemorrhage rates through a quality improvement project using a Swedish National quality register: a case study
ConclusionsThe rates of PTH can be reduced with a QIP. A national quality register can be used not only to identify areas for improvement but also to evaluate the impact of subsequent improvement efforts and thereby guide professional development and enhance patient outcomes. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

A blind area of origins of epistaxis: technical or cognitive?
ConclusionsThe arterial bleeding small area of anterior lateral wall of nasal cavity corresponding to the nasal back and the nasal part of the nasal cavity roof accounted for more than 10% of anterior epistaxis and a thorough endoscopic examination should include these area with angled endoscope. Then radiofrequency and selective packing will sharply reduce the bleeding duration. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Extramucosal pyriplasty without stenting for management of pyriform aperture stenosis
ConclusionsExtramucosal pyriplasty with decompression of the NLD without stenting is a treatment modality for CNPAS that provides prompt sustainable relief of nasal obstruction and avoids the drawbacks of stenting and shortcomings of the current conservative methods. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Cripto-1 is overexpressed in carcinoma ex pleomorphic adenoma of salivary gland
AbstractIntroductionCripto-1 is a member of the epidermal growth factor —Cripto-1/FRL-1/Cryptic family. Besides being critical for early embryonic development, Cripto-1 is also associated with the development and behavior of several cancers. Objective: We analyzed the immunoexpression of Cripto-1 in normal salivary glands (NSGs), pleomorphic adenomas (PAs), and carcin oma ex pleomorphic adenomas (CaExPAs) of salivary glands.MethodsA total of 12 NSGs, 16 PAs and 12 CaExPAs underwent immunohistochemical study by the polymeric biotin-free technique. Immunopositive cells were evaluated semiquantitatively (scores 0 &ndash...
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Effects of gadolinium-based contrast agents on submandibular gland tissue in rats
AbstractAimThe aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on submandibular gland tissue (SGT) of the rats.Material and methodTwenty-four Sprague Dawley female rats were included the study. Group 1 was determined as a control group (n = 6). Group 2 was determined as saline group (n = 6). Group 3 was determined as Omniscan group (n = 6) and received only intraperitoneal (IP) 0.1 mmol (0.2 mL/kg)/kg gadodiamide ...
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

The multiplanar analysis of the retromandibular vein in surgical planning for parotid gland tumors
ConclusionsThe multiplanar modality, combined with the evaluation of the parapharyngeal space, is effective in helping the surgeon to achieve accurate planning: it enables the tumor to be located and the facial nerve course predicted with a good precision. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Antero- vs. retrograde nerve dissection in parotidectomy: a systematic review and meta-analysis
AbstractIntroductionThe retrograde approach (RP) to nerve identification is a method seldom used in parotid surgery. A systematic review comparing this method to the standard anterograde approach (AP) with respect to facial nerve palsy (FNP) does not currently exist.MethodsIn a meta-analysis according to the PRISMA statement, eight publications, including one randomized controlled trial, were selected. The primary aim was to compare the temporary and permanent FNP resulting from the two dissection methods. Facial nerve function was graded according to the House –Brackmann Scale. The secondary goal was a comparison of...
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Single nucleotide polymorphisms of IL-13 and CD14 genes in allergic rhinitis: a meta-analysis
AbstractPurposeThe aim of this study was to conduct a meta-analysis for single nucleotide polymorphisms (SNPs) in interleukin-13 (IL-13) and cluster of differentiation 14 (CD14) genes and the risk for allergic rhinitis (AR).MethodsWe screened studies identified through seven databases including Pubmed, Medline, Web of Science, Embase, China Biology Medicine disc, Wanfang, and China Academic Journal Network Publishing Database. The odds ratios (ORs) and 95% confidence intervals (CIs) were determined to assess the association under allelic, dominant and recessive models.ResultsTwelve studies with a total of 8547 participants...
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Procedure-specific assessment tool for flexible pharyngo-laryngoscopy: gathering validity evidence and setting pass –fail standards
AbstractObjectiveThe attainment of specific identifiable competencies is the primary measure of progress in the modern medical education system. The system, therefore, requires a method for accurately assessing competence to be feasible. Evidence of validity needs to be gathered before an assessment tool can be implemented in the training and assessment of physicians. This evidence of validity must according to the contemporary theory on validity be gathered from specific sources in a structured and rigorous manner. The flexible pharyngo-laryngoscopy (FPL) is central to the otorhinolaryngologist. We aim to evaluate the fle...
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

The predictive value of polysomnography combined with quality of life for treatment decision of children with habitual snoring related to adenotonsillar hypertrophy
ConclusionSchool-age children aged    1/h and mouth breathing scored>  4 points were more likely to receive AT during the disease process and thus require increased attention. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Septal branches of the anterior ethmoidal artery: anatomical considerations and clinical implications in the management of refractory epistaxis
ConclusionsThe sbAEA are of great interest in endoscopic endonasal surgery, both as surgical landmarks and as feeding vessels for a variety of pedicled nasal flaps. What is more, they can be crucial for the management of refractory epistaxis. Their selective endoscopic coagulation represents an effective and safe procedure in cases of difficult-to-control epistaxis from the upper nasal fossa, with several advantages over nasal packing. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research

Polymorphous adenocarcinoma of the salivary glands: reappraisal and update
AbstractAlthough relatively rare, polymorphous adenocarcinoma (PAC) is likely the second most common malignancy  of the minor salivary glands (MiSG). The diagnosis is mainly based on an incisional biopsy. The optimal treatment comprises wide surgical excision, often with adjuvant radiotherapy. In general, PAC has a good prognosis. Previously, PAC was referred to as polymorphous low-grade adenocarcinoma (PLGA ), but the new WHO classification of salivary gland tumours has also included under the PAC subheading, the so-called cribriform adenocarcinoma of minor salivary glands (CAMSG). This approach raised controver...
Source: European Archives of Oto-Rhino-Laryngology - May 14, 2018 Category: ENT & OMF Source Type: research