Current management of arytenoid sub-luxation and dislocation
ConclusionAS/AD is a mechanical disorder of the larynx that can be successfully treated if promptly diagnosed. Clinical trials and multi-centric studies are necessary to set management guidelines. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

LncRNA-MALAT1 is a promising biomarker for prognostic evaluation of tongue squamous cell carcinoma
ConclusionsThe expression level of MALAT1 is closely related with progression of tongue SCC. Furthermore, MALAT1 can serve as an independent biomarker for prognostic evaluation of tongue SCC. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Surgical resection of oral cancer: en-bloc versus discontinuous approach
ConclusionThe more invasive approach does not correlate to a better outcome. In selected cases, DR is an oncologically safe technique; EBR is still a valid option to treat advanced oral cancers (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Prematurity and associated future paediatric airway pathology: experience from a single tertiary paediatric ENT centre
AbstractPurposeEnhanced management of the pre-term patient has resulted in improved survival rates in increasingly premature patients. Although prematurity predisposes to congenital airway pathology, there is also increased risk of endotracheal intubation, and therefore acquired subglottic pathology. We sought to evaluate airway pathology in children outside the neonatal period with a history of prematurity to explore the relationship between prematurity and upper airway pathologies.MethodsData for patients undergoing elective microlaryngobronchoscopy (MLB) at our centre were collected prospectively over a 5-year period. P...
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Platelet-rich plasma for laryngotracheal reconstruction: an experimental study
ConclusionsApplication of PRP contributed to better healing in airway surgery by promoting a release of growth factors that stimulate new cartilage formation and angiogenesis. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Bencycloquidium bromide nasal spray is effective and safe for persistent allergic rhinitis: a phase III, multicenter, randomized, double-blinded, placebo-controlled clinical trial
AbstractPurposeTo investigate the efficacy and safety of bencycloquidium bromide nasal spray (BCQB) in patients with persistent allergic rhinitis (PAR).MethodsWe enrolled 720 patients from 15 hospitals across China and randomly assigned them into BCQB group or placebo group (90  μg per nostril qid) to receive a 4-week treatment. Visual analog scale (VAS) for rhinorrhea, sneezing, nasal congestion, itching and overall symptoms were recorded by patients every day. Anterior rhinoscopy scoring was completed by doctors on every visit. Adverse events were recorded in detail.ResultsA total of 354 and 351 patients were inc...
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

History of medicine is not a game
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Endoscopic endonasal approach for repairing an outwardly herniated blow-out fracture lateral to the infraorbital nerve
AbstractBackgroundTo repair a blow-out fracture, the endonasal approach is indicated when the center of the fracture occurs in the orbital floor medial to the infraorbital nerve, or when the orbital tissue is herniated inwards; additionally, the combined endonasal and transmaxillary approach is indicated for fractures of the anterior and lateral parts of the orbital floor.Method and conclusionThe use of endoscopic modified medial maxillectomy and special instruments enabled the surgeon to repair an outwardly herniated blow-out fracture by the endonasal approach alone, despite the center of the fracture being in the orbital...
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Endoscope holder-assisted endoscopic coblation tonsillectomy
ConclusionEndoscope gives a panoramic view, better optics, magnified image of the bleeders and hence there is applicability of the endoscope holder for endoscopic tonsillectomy. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

COVID-19: what happened to all of the otolaryngology emergencies?
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Histological type homogeneity: a cornerstone in analyzing temporal bone malignancies data
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Further arguments against both the first description of cholesteatoma by Hippocrates, and the allusion to the tympanic membrane in the Ebers Papyrus
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

The utilization of Chronic Otitis Media Questionnaire-12 in chronic otitis media with or without cholesteatoma
ConclusionThe COMQ-12 could be a useful tool to differentiate chronic otitis media with or without cholesteatoma. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Response to the Letter to the Editor: “Histological type homogeneity—a cornerstone in analyzing temporal bone malignancies data”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Pathological evaluation of the accuracy of a fluorescence spectroscopy system for detecting parathyroid glands
ConclusionWe consider that this technique is useful, however, we have to exercise care in malignant cases as the true-positive rate may be low. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

S ıngle sıded deafness after sudden hearıng loss: late effect on cochlear nerve sıze
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Letter to the Editor regarding “Single-sided deafness after sudden hearing loss: late effect on cochlear nerve size” by Islamoglu et al. European Archives of Oto-Rhino-Laryngology (2020) 277:2423–2426
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 10, 2020 Category: ENT & OMF Source Type: research

Modified submental platysmal adipomyofascial flap: is it a reliable alternate reconstructive option for small- to mid-sized defects especially in male patients with oral/oropharyngeal cancer?
ConclusionModified submental platysmal adipomyofascial flap can be considered as a good alternative in male patients for reconstruction of small- to mid-sized oral cavity/oropharyngeal defects post-resection, especially during the prevailing pandemic crisis. It is an oncologically safe procedure with the major advantage of providing a hairless flap for oral cavity, tonsillar and BOT resection defects with lesser donor site morbidity. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 9, 2020 Category: ENT & OMF Source Type: research

Association of cervical vestibular-evoked myogenic potential tuning property test results with MRI findings of endolymphatic hydrops in Meniere ’s disease
ConclusionEH(+) or NR in the cVEMP tuning property test correspond well to EH positivity in the MRI findings. The cVEMP tuning property test is useful for screening and following up EH. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 9, 2020 Category: ENT & OMF Source Type: research

Can hearing amplification improve presbyvestibulopathy and/or the risk-to-fall ?
DiscussionHearing and balance function degenerate independently from each other and large interindividual differences require a separate neurotological examination of each patient. However, hearing amplification is most helpful to improve postural stability, particularly in the elderly. Future research should focus on controlled, prospective clinical trials where a standardized test battery covering the audiological and neurotological profile of each elderly patient pre/post prescription of hearing aids and/or cochlear implantation should be followed up (for at least 1  year) so that also the balance improvements and ...
Source: European Archives of Oto-Rhino-Laryngology - October 9, 2020 Category: ENT & OMF Source Type: research

Investigation of the serum vitamin D level in infants followed up with the diagnosis of laryngomalacia: a case –control study
AbstractObjectiveThe possible etiological relationship of the vitamin D with laryngomalacia is unclear. The aim of the study was to demonstrate the relationship between laryngomalacia and vitamin D levels.MethodsTwenty-three non-syndromic babies under the age of 1  year who were diagnosed with laryngomalacia were included in the study group. Forty healthy babies were included in the control group. The detailed anamnesis was obtained and a complete systemic physical examination, a flexible endoscopic laryngeal examination, and laboratory tests [calcium (Ca), phosphorus (P), alkaline phosphatase (ALP), parathormone (PTH...
Source: European Archives of Oto-Rhino-Laryngology - October 6, 2020 Category: ENT & OMF Source Type: research

Patient-reported factors that influence the vestibular schwannoma treatment decision: a qualitative study
ConclusionKnowledge of the factors that influence decision-making helps physicians to tailor their consultations to arrive at a true shared decision on vestibular schwannoma management. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 6, 2020 Category: ENT & OMF Source Type: research

Clinical characteristics and prognosis of elderly nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy
ConclusionThe survival outcome of patients aged  ≥ 70 years receiving IMRT only was similar to chemoradiotherapy with significantly less acute toxicities. Among the population, age is significantly prognostic for survival outcomes. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 5, 2020 Category: ENT & OMF Source Type: research

Non-idiopathic peripheral facial palsy: prognostic factors for outcome
AbstractObjectivesThere is a lack of data on patients ’ and diagnostic factors for prognostication of complete recovery in patients with non-idiopathic peripheral facial palsy (FP).MethodsCohort register-based study of 264 patients with non-idiopathic peripheral FP and uniform diagnostics and standardized treatment in a university hospital from 2007 to 2017 (47% female, median age: 57  years). Clinical data, facial grading, electrodiagnostics, motor function tests, non-motor function tests, and onset of prednisolone therapy were assessed for their impact on the probability of complete recovery using univariable ...
Source: European Archives of Oto-Rhino-Laryngology - October 5, 2020 Category: ENT & OMF Source Type: research

ACE2 expression in allergic airway disease may decrease the risk and severity of COVID-19
AbstractThe coronavirus disease (COVID-19) is caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and presents with respiratory symptoms which can be life threatening in severe cases. At the start of the pandemic, allergy, asthma, and chronic obstructive pulmonary disease (COPD) were considered as risk factors for COVID-19 as they tend to exacerbate during respiratory viral infections. Recent literature has not shown that airway allergic diseases is a high-risk factor or that it increases the severity of COVID-19. This is due to a decrease in Angiotensin-converting enzyme 2 (ACE2) gene expression in the ...
Source: European Archives of Oto-Rhino-Laryngology - October 5, 2020 Category: ENT & OMF Source Type: research

Platelet-rich fibrin: an autologous biomaterial for healing assistance of pharyngeal repair in total laryngectomy
ConclusionPRF application on the pharyngeal repair after total laryngectomy enhances the healing process and consequently decreases the incidence of PCF. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 2, 2020 Category: ENT & OMF Source Type: research

Impact of depressive disorders on quality of life after middle ear surgery in patients with chronic otitis media
AbstractPurposeThe aim of this study was to determine whether preoperative depressive symptoms influence health-related quality of life (HRQOL) after middle ear surgery in patients with chronic otitis media (COM).MethodsThis prospective clinical case study was conducted at a tertiary referral center. All 102 patients who had undergone middle ear surgery for COM were assessed clinically and by audiometric testing (pure tone audiometry) in pre- and postoperative settings. Disease-specific HRQOL was assessed by the validated chronic otitis media outcome test 15 (COMOT-15) and the Zurich chronic middle ear inventory (ZCMEI-21)...
Source: European Archives of Oto-Rhino-Laryngology - October 2, 2020 Category: ENT & OMF Source Type: research

Otolaryngological manifestations of hospitalised patients with confirmed COVID-19 infection
ConclusionThe most common otolaryngologic symptoms of COVID-19 infection are known as sore throat, smell and/or taste disturbances. However, our study showed that these patients can be seen with different symptoms in otological or laryngeal areas. Therefore, a more careful evaluation should be made in terms of otolaryngologic symptoms when COVID 19 infection is suspected. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 2, 2020 Category: ENT & OMF Source Type: research

Post-intubation tracheal stenosis in COVID-19 patients
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - October 2, 2020 Category: ENT & OMF Source Type: research

Cancer stem cell markers in adenocarcinoma of the salivary glands - reliable prognostic markers?
AbstractPurposeAdenocarcinoma of the salivary glands is of low incidence and a broad range of histopathological subtypes. Cancer stem cell markers (CSC) might serve as novel prognostic parameters. To date, only a few studies examined the expression of CSC in adenocarcinoma of the salivary glands with diverging results. To further investigate the reliability in terms of prognostic value, a histopathological analysis of CSCs on a cohort of patients with adenocarcinomas of the major salivary glands was performed.MethodsTumor samples of 40 consecutive patients with adenocarcinoma of the major salivary gland treated with curati...
Source: European Archives of Oto-Rhino-Laryngology - October 2, 2020 Category: ENT & OMF Source Type: research

Prevalence of the prelacrimal recess in maxillary sinus and its medial bony wall dimensions
ConclusionA large individual variation exists in the anatomy of PLR, including its prevalence and dimensions of its medial bony wall. When considering the intranasal endoscopic prelacrimal recess approach, the surgeons should carefully evaluate the anatomical structure of the PLR preoperatively so as to minimize the risks of surgical complications. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 30, 2020 Category: ENT & OMF Source Type: research

Topical lignocaine anaesthesia for oropharyngeal sampling for COVID-19
ConclusionTopical lignocaine, while improving the comfort of the procedure of oropharyngeal  sampling for patient did not alter the SARS-CoV-2 viral load that was detected in nasal and oropharyngeal samples taken together. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 30, 2020 Category: ENT & OMF Source Type: research

Topographic anatomy of the ınternal branch of the superior laryngeal nerve
ConclusionOur study demonstrated the surgical and topographical features of the ibSLN with respect to the THM, and provided a more precise knowledge of its anatomy in laryngectomy patients. It thus may help head and neck surgeons identify this nerve. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 30, 2020 Category: ENT & OMF Source Type: research

The evaluation of prognostic factors in endoscopic cartilage tympanoplasty
This study included 312 patients who underwent transcanal endoscopic type I cartilage tympanoplasty. The effects of sex, the affected side, the size of the perforation, the location of the perforation, the absence of myringosclerosis, external ear canal protrusion, the condition of the contralateral ear, and surgical experience on the rate of graft success and hearing improvement were investigated.ResultsThe affected side, sex, location of the perforation, myringosclerosis, the condition of contralateral ear, and surgical experience did not significantly affect the surgical success (p >  0.05). However, th...
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

External auditory canal carcinoma: clinical characteristics and long-term treatment outcomes
This study aims to evaluate the clinical characteristics and long-term outcomes of EAC carcinoma in a tertiary referral centre in a period of 15  years and identify independent prognostic factors.MethodsRetrospective observational study enrolling all patients with primary EAC carcinoma who underwent primary surgical treatment at the Portuguese Institute of Oncology (Lisbon) between 2004 and 2018. Epidemiological, clinical, histopathological and surgical data were retrieved from clinical records and analysed.ResultsTwenty-seven patients were identified, with a median age of 77  years (range 29–92 years)...
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Device-related epistaxis risk: continuous-flow left ventricular assist device-supported patients
AbstractBackgroundThe aim of this study was to analyze the effect of device-dependent factors on epistaxis episodes comparing patients supported with a continuous-flow left ventricular assist device (CF-LVAD) to patients under the same antithrombotic therapy.MethodsPatients who underwent CF-LVAD between 2012 and 2018 were reviewed retrospectively from the institutionally adopted electronic database. Patients who underwent mitral valve replacement (MVR) surgery receiving the same anticoagulant and antiaggregant therapy were included as a control group. Demographics, epistaxis episodes, and nonepistaxis bleeding between the ...
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Olfactory and gustatory abnormalities in COVID-19 cases
AbstractPurposeAt the time of writing, there is a pandemic affecting virtually every country on Earth. There is considerable discussion amongst clinicians as well as lay people about anosmia and ageusia in COVID-19 sufferers. We aimed to report the results from comprehensive olfactory and gustatory testing in a series of hospital in-patients.MethodsThe prospective study evaluated 81 individuals with a COVID-19 infection, as confirmed by 2019 n-cov Real-Time PCR laboratory testing. The control group consisted of forty individuals with COVID-19 negative. Olfactory and gustatory testings were carried out by an examiner utiliz...
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Added value of susceptibility-weighted imaging to diffusion-weighted imaging in the characterization of parotid gland tumors
AbstractPurposeTo assess the added value of susceptibility-weighted imaging (SWI) to diffusion-weighted imaging (DWI) in the characterization of parotid gland tumors.MethodsSeventy-eight patients with pathologically confirmed parotid gland tumors, who underwent DWI and SWI for pre-surgery evaluation, were enrolled. Apparent diffusion coefficient (ADC) and degree of intratumoral susceptibility signal intensity (ITSS) were measured and compared between benign and malignant groups, and among pleomorphic adenoma (PA), Warthin tumor (WT) and malignant tumor (MT). Independent samplet test, one-way analysis of variance and receiv...
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Risk factors for residual mouth breathing in children who had completely resolved obstructive sleep apnea after adenotonsillectomy
ConclusionsOlder age, large adenoid size, and presence of dentofacial abnormalities in children with OSA may be the risk factors for residual mouth breathing after successfully resolved OSA. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Postoperative morbidity after adenotonsillectomy versus adenopharyngoplasty in young children with obstructive sleep apnea: an RCT
ConclusionThe results regarding postoperative morbidity were in favor of ATE and the results from our previous report showed no advantages of APP. Therefore, APP should not be recommended in young, otherwise healthy children with OSA. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

The primary tumor resection in patients with distant metastatic laryngeal carcinoma
AbstractBackgroundThe role of primary tumor resection in patients with distant metastatic laryngeal carcinoma (DMLC) has not been clarified completely. Thus, we used propensity score matching (PSM) and survival analysis to address this issue.MethodsThe PSM was utilized to avoid selection bias and disproportionate distributions of the confounding factors. Kaplan –Meier estimates and Cox proportional hazard analysis were utilized to evaluate overall survival (OS) and cancer-specific survival (CSS).ResultsFrom the Surveillance, Epidemiology, and End Results Program database, a cohort of 480 patients with DMLC were inclu...
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Laryngopharyngeal reflux and autonomic nerve dysfunction: what about stress?
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Claviculotracheopexy for complex airway reconstructions
ConclusionClaviculotracheopexy can be used as a complementary procedure in complex airway reconstructions. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Acetic acid disinfection as a potential adjunctive therapy for non-severe COVID-19
ConclusionsConsidering its potential benefits and high availability, acetic acid disinfection appears to be a promising adjunctive therapy in cases of non-severe COVID-19 and deserves further investigation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

The nasal tent: an adjuvant for performing endoscopic endonasal surgery in the Covid era and beyond
ConclusionThe use of a nasal tent is a simple and affordable method to limit particle spread during high-risk aerolisation procedures during the Covid era and beyond. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Reply to “Could a mannequin simplify rhinopharyngeal swab collection in COVID 19 patients?”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

The role of fine ‑needle aspiration biopsy (FNAB) in the diagnostic management of parotid gland masses with emphasis on potential pitfalls
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Correction to: ATF5 involved in radioresistance in nasopharyngeal carcinoma by promoting epithelial-to-mesenchymal phenotype transition
The article ATF5 involved in radioresistance in nasopharyngeal carcinoma by promoting epithelial-to-mesenchymal phenotype transition, written by Yu Shuai, Erxi Fan, Qiuyue Zhong, Guangyong Feng, Qiying Chen, Xiaoxia Gou, Guihai Zhang, was originally published. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Moderate hypofractionation for early laryngeal cancer improves local control
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research

Reply to letter to the editor “The role of fine-needle aspiration biopsy (FNAB) in the diagnostic management of parotid gland masses with emphasis on potential pitfalls”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 10, 2020 Category: ENT & OMF Source Type: research