The changing face of Irish head and neck cancer epidemiology: 20  years of data
ConclusionHNC survival in Ireland has improved in line with increasing recognition of the value of multidisciplinary assessment, subspecialisation in cancer care, and targeted therapies based on tumour subsites. Survival in the elderly cohort remains poor despite increasing recognition of the challenges such cases pose. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

A novel MYH9 mutation related to non-syndromic delayed post-lingual sensorineural hearing loss
ConclusionThe identification and detection of a novelMYH9 mutation may be of great significance to provide the basis for gene function research and genetic consultation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Assessment of preoperative and postoperative cardiac function in children with adenotonsillar hypertrophy: a prospective cohort study
ConclusionWe have concluded that there can be subclinical cardiac dysfunctions which occurs as a result of chronic upper airway obstruction due to untreated adenotonsillar hypertrophy. Routine cardiac screening in children presenting with sleep disordered breathing associated with adenotonsillar hypertrophy may be helpful in identifying and preventing the development of cardiopulmonary complication. These changes can be reversed by performing adenotonsillectomy. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Benefit on daily listening with technological advancements: comparison of basic and premium category hearing aids
ConclusionThe users of premium category devices revealed better ease of communication in daily environments, whereas performance of these devices on other listening domains remains questionable. Cost effectiveness was reported to be better by the users of basic hearing aids. A prospective and controlled paired series comparison of hearing aid performance needs to be performed to confirm these findings. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

The role of Glut-1 and H+/K+-ATPase expression in hyperplasia of mice laryngeal epithelium induced by pepsin
ConclusionsPepsin-containing artificial gastric juice promoted mouse laryngeal epithelial hyperplasia associated with abnormal expression of Glut-1 and H+/K+-ATPase α, β. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Absence of multinucleated giant cell reaction as an indicator of tumor progression in oral tongue squamous cell carcinoma
ConclusionTaken together, the results of this study suggest that the absence of MGC reaction may represent an indicator of tumor progression in OTSCCs. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Open partial horizontal laryngectomy for T2 –T3–T4a laryngeal cancer: oncological outcomes and prognostic factors of two Italian hospitals
ConclusionThe oncological outcomes from our study show that OPHL for advanced laryngeal cancer can guarantee a high percentage of success. Accurate patient selection is of utmost importance to differentiate advanced disease amenable to conservative surgery, and treatment options should consider selected criteria based on tumour and patient features. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Efficacy of sodium hyaluronate in relieving nasal symptoms of children with intermittent allergic rhinitis: a randomized controlled trial
ConclusionThe addition of HA to NC as an adjunct therapy in children with intermittent AR has limited beneficial effects in our study and deserves further investigation.Trial RegistryThe clinical trial registration number ID:NCT04752956. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

A 10-year review of malignant otitis externa: a new insight
ConclusionThis study has revealed the evidence of progression of MOE based on the proposed radiological stratification. This stratification is simple and practically applicable in clinical settings. We suggest the use of our proposed treatment algorithm as a standard diagnostic and treatment protocol for MOE. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Petrous bone cholesteatoma: our experience of 20  years and management of two giant cases affecting rhinopharynx
ConclusionOtologic endoscope combined with traditional microscopic surgery could reduce the exposure in surgery. For extremely extended cases of PBC, supplementary transnasal endoscopic approach deserves to be considered for the traditional temporal bone approach. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Cervical suppurative lymphadenitis in children: microbiology, primary sites of infection, and evaluation of antibiotic treatment
ConclusionS. aureus was the predominant pathogen in paediatric CSL at all cervical levels, and even in cases with evidence of primary site infection not normally associated withS. aureus. We were unable to underscore the importance of antibiotic treatment coveringS. aureus based on evaluation of the clinical outcomes. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Is intraoperative margin sampling necessary in inverted papilloma resection?
ConclusionsAccording to our results, intraoperative margin sampling did not affect the recurrence rate of IP, and therefore, its routine use should be questioned. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Marital status and survival in laryngeal squamous cell carcinoma patients: a multinomial propensity scores matched study
ConclusionMarital status showed a significant association with the survival status of LSCC patients. Importantly, the outcome of married patients was better, while widowed patients tended to have worse prognosis. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Response to a letter to the editor “A prediction model for recurrence after translabyrinthine surgery for vestibular schwannoma: towards personalized postoperative surveillance”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research

Indications for surgery in necrotizing otitis externa
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - May 18, 2022 Category: ENT & OMF Source Type: research