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Endoscopic transnasal surgery of clival lesions: our experience
ConclusionsClival lesions represent a heterogeneous group of lesions located in a very complex and difficult area. EEA and TO approaches are safe and mini-invasive, with lower morbidity and with postoperative complications when compared to the traditional open approaches, according to the extent and type of pathology. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Improved overall survival in head and neck cancer patients after specific therapy of distant metastases
ConclusionsOur retrospective analysis demonstrates a significant survival benefit for HNSCC patients who received a specific therapy regarding distant metastasis irrespective of localization as compared to a matched control cohort. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Effect of long-term oral appliance therapy on obstruction pattern in patients with obstructive sleep apnea
ConclusionsWe found evidence possibly indicating decreased obstruction at the levels of the velum and epiglottis after long-term use of oral appliances. We suggest further cohort studies to confirm these findings. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Olfactory cleft evaluation: a predictor for olfactory function in smell-impaired patients?
ConclusionOlfactory cleft evaluation using the OC –LK score correlates with the olfactory function in patients with sino-nasal smell disorder. This diagnostic tool may reflect the underlying pathophysiological mechanism of sino-nasal smell loss, and therefore, should complement olfactory diagnostics in patients with sino-nasal smell disorder. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Intralabyrinthine schwannomas: a new surgical treatment
ConclusionThe endoscopic approach to cochlear schwannoma represents a good treatment option for patients and should be preferred to other more invasive surgical techniques when indicated, to reduce complications, hospitalization, and offer to patients the chance to eradicate the disease, thus avoiding the stress of a long-life radiological follow-up.Level of evidence4. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Predictive factors of a beneficial quality of life outcome in patients undergoing primary sinonasal surgery: a population-based prospective cohort study
ConclusionsQoL change after primary SP and ESS varies. A preoperative SNOT-22 score of at least 30 best predicted a beneficial QoL outcome after both procedures. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Clinical course of rhinosinusitis and efficacy of sinonasal evaluation in kidney transplant recipients: review of 1589 patients
ConclusionsThe prevalence and recurrence rate of rhinosinusitis in KT patients was not increased after KT. Symptomatic patients needed surgical or medical treatment before KT, but asymptomatic patients showed no deterioration of clinical course after KT. Routine sinonasal evaluation for asymptomatic patients is not recommended before KT. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Towards an in vitro fibrogenesis model of human vocal fold scarring
ConclusionBased on the principles of MMC we could successfully establish a laryngeal fibrogenesis model employing hVFF. Our finding of dose-dependent HGF effects is important before going into clinical trials in humans and has never been shown before. Our model provides a novel option to screen various potential antifibrotic compounds under standardized conditions in a short time. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

The use of drug-induced sleep endoscopy in England and Belgium
ConclusionsClinicians in Belgium were more favourable to using DISE than in the UK. Differences in its clinical effectiveness were apparent between the two countries. A consensus on patient selection, method of sedation and an effective classification system seemed to be lacking from both countries. Further education is required to raise awareness for the use of DISE. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Sentinel lymph node biopsy in cutaneous head and neck melanoma
This study aims to confirm the feasibility, accuracy and low morbidity of SLNB in CHNM and evaluate its prognostic value.MethodsA monocentric and retrospective study on patients with CHNM treated in our tertiary care center (Gustave Roussy) between January 2008 and December 2012 was performed. The feasibility, morbidity and prognostic value of this technique were analysed.ResultsOne hundred and twenty-four consecutive patients were included. SLNB was realized in 97.6% of the cases. No significant post-operative morbidity was observed. Nineteen percents of patients had a positive SN while only 14.3% of complete lymph node d...
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Functional and cosmetic donor site morbidity of the radial forearm-free flap: comparison of two different coverage techniques
ConclusionsThe direct closure procedure is quick, simple and can be performed without secondary donor site morbidity. For wound healing, cosmetic and function of the forearm and hand, no inferior results can be measured for the direct procedure compared to the indirect coverage technique. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Arterial spin labeling perfusion-weighted MR imaging: correlation of tumor blood flow with pathological degree of tumor differentiation, clinical stage and nodal metastasis of head and neck squamous cell carcinoma
ConclusionTBF is a non-invasive imaging parameter that well correlated with pathological degree of tumor differentiation, clinical stage of tumor and nodal metastasis of HNSCC. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Pharyngeal fistulas after total laryngectomy with and without tracheostoma plasty according to Herrmann
ConclusionsPerformance of TPH after TL does not increase the incidence of PF. Thus, TPH can be considered as a safe alternative surgical technique for the shaping of the tracheostoma following TL. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Airwayplasty: long-term outcome of nasal wall lateralisation
ConclusionsThis novel approach to nasal obstruction can provide good long-term functional results for patients suffering from nasal obstruction. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Efficacy and safety of LigaSure ™ small jaw instrument in thyroidectomy: a 1-year prospective observational study
AbstractPurposeTo compare the efficacy and safety profiles of LigaSure ™ small jaw instrument (LSJI) versus conventional technique in patients undergoing open thyroidectomy.MethodsThis single-center, prospective, observational study conducted in Zhejiang Provincial Cancer Hospital enrolled patients who underwent thyroidectomy between September 2013 and September 2014. The primary study outcomes included determination of blood loss, operative duration, length of hospital stay, and drainage volume. The secondary outcomes included evaluation of recurrent laryngeal nerve palsy, postoperative bleeding, and hypoparathyroid...
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Potential risk factors associated with the development of synechiae following functional endoscopic sinus surgery
ConclusionPatients undergoing primary FESS and NSR are at greatest odds of developing postoperative synechiae. Methods of assessing risk factors and preventing synechiae formation in this population should be evaluated in future prospective investigations. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Endoscopic visualization to the anterior surface of the malleus and tensor tympani tendon in congenital cholesteatoma
ConclusionsTotal endoscopic or endoscope-assisted surgery could help surgeons directly visualize the ASMT in children, with negligible risks of hearing deterioration, postoperative complications, and recurrent disease. Our study might suggest that endoscopic ear surgery should be considered in patients with CC in the ASMT. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

RETRACTED  ​ARTICLE: Interleukin-33 promotes helper T cell type-2/17 inflammation in children with allergic rhinitis
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Authors ’ response to Commentary on “European status on temporal bone training: a questionnaire study”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Correction to: Long-term hearing results of stapedotomy: analysis of factors affecting outcome
AbstractThe given and family names of all the co-authors are incorrect in the published article. The correct names should read as follows: (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 10, 2018 Category: ENT & OMF Source Type: research

Cortical processing of speech in individuals with auditory neuropathy spectrum disorder
ConclusionResults indicated that the brain networks and regions activated in individuals with ANSD during detection and discrimination of speech sounds are different from normal hearing individuals. In general, normal hearing individuals showed more focused activations while in individuals with ANSD activations were diffused. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 9, 2018 Category: ENT & OMF Source Type: research

Molecular markers in well-differentiated thyroid cancer
ConclusionThe prevalence of these mutations in thyroid nodule is high and it is a continuously evolving field. Clinicians should stay informed as recommendation on the use of these markers is expected to evolve. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 6, 2018 Category: ENT & OMF Source Type: research

Effect of voice therapy on vocal fold polyp treatment
ConclusionVoice therapy can improve voice quality to some extent during the treatment of vocal fold polyps. However, VT alone is unsatisfactory compared to surgery alone. Pre-surgical VT can enhance the ultimate success of treatment. A young age, small polyps, and short duration of dysphonia may increase the possibility of benefiting from VT. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 6, 2018 Category: ENT & OMF Source Type: research

Clinical utility of dynamic-enhanced MRI in salivary gland tumors: retrospective study and literature review
This study focused on the time-intensity curve (TIC) after injection, peak time (Tpeak), washout ratio (WR) as well as the gradient of enhancement and washout profile.ResultsThe histological diagnoses included pleomorphic adenoma (PMA) in 53 cases, the Warthin tumors (WT) in 14 cases and malignant tumors (MT) in 26 cases. Incorrect diagnosis rate of FNAC and IFS were 5.2 and 8.3%, respectively. The TIC revealed differences among the three types of tumors. Tpeak as well as WR also revealed significant differences (p 
Source: European Archives of Oto-Rhino-Laryngology - April 6, 2018 Category: ENT & OMF Source Type: research

The clinical outcome and microbiological profile of bone-anchored hearing systems (BAHS) with different abutment topographies: a prospective pilot study
ConclusionsThere was no difference in the clinical outcome with the use of polished versus machined abutment at 3 and 12  months after implantation. The present pilot trial largely confirmed a suitable study design, sampling and analytical methodology to determine the effects of modified BAHS abutment properties.Level of evidence2. Controlled prospective comparative study. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 5, 2018 Category: ENT & OMF Source Type: research

Imaging evaluation of electrode placement and effect on electrode discrimination on different cochlear implant electrode arrays
ConclusionThe Nucleus CI532 offers a better perimodiolar placement. HF and IPI measurements provide information about the electrodes location inside the cochlea, being related to electrode discrimination. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 2, 2018 Category: ENT & OMF Source Type: research

Poor oral intake causes enteral nutrition dependency after concomitant chemoradiotherapy for pharyngeal cancers
ConclusionsA long duration of NOI was more strongly related to EN dependency than nutritional factors. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 2, 2018 Category: ENT & OMF Source Type: research

Organ preservation surgery for patients with T4a laryngeal cancer
ConclusionOur retrospective analysis of 32 patients with T4a SCCL showed that successful organ preservation surgery is safe and reliable, and associated with a relatively acceptable disease-free survival, normal swallowing function, and acceptable voice quality. More patients with T4a SCCL who wish to preserve the larynx should be considered for organ preservation surgery. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 2, 2018 Category: ENT & OMF Source Type: research

Potassium titanyl phosphate laser-induced inflammatory response and extracellular matrix turnover in rabbit vocal fold scar
The objectives of this study were to observe the regulating effect of KTP laser and Nd:YAG laser in the repair of vocal fold scars.MethodsAll rabbits were injured in the muscular layer with a sharp instrument, and then the vocal folds were treated with a KTP laser and a Nd:YAG laser at a power of 2, 4, 6 and 8  W 1 month after the injury. One month after treatment, the rabbits were killed and the throats were removed to detect changes in histology and gene expression of the vocal fold scar after laser therapy.ResultsThe best efficacy of all KTP laser treatment groups was the KTP laser 6  W group. Regarding t...
Source: European Archives of Oto-Rhino-Laryngology - April 2, 2018 Category: ENT & OMF Source Type: research

Health-related quality of life in patients with major salivary gland carcinoma
ConclusionsDiagnosis and treatment of MSGC has influence on overall QOL. Postoperative radiation has the greatest impact on QOL. This is one of the largest study evaluating QOL in patients with salivary gland carcinoma using the UWQOL. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 5, 2018 Category: ENT & OMF Source Type: research

Cochlear implantation in the elderly: outcomes, long-term evolution, and predictive factors
ConclusionThis study shows that cochlear implantation in the elderly is as safe, useful, and worthwhile as in young adults. Age has a low influence in cochlear implant outcomes; however, we have found the significant influence of the side of implantation, the use of hearing aids, and the duration of hearing loss in the short- and long-term results. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 5, 2018 Category: ENT & OMF Source Type: research

Olfactory and gustatory functions after free flap reconstruction and radiotherapy for oral and pharyngeal cancer: a prospective follow-up study
AbstractBackgroundThe senses of smell and taste can be adversely affected by both tumour- and treatment-related factors amongst head and neck cancer patients. The consequences may negatively impact nutritional status as well as quality of life in this patient population.Patients and methodsThis prospective longitudinal follow-up study is consisted of 44 patients treated for oral cavity, oropharyngeal or hypopharyngeal cancer with tumour resection and microvascular free tissue transfer reconstruction at the Helsinki University Hospital, Helsinki, Finland. Thirty-nine (89%) of them also received radiotherapy. The senses of s...
Source: European Archives of Oto-Rhino-Laryngology - March 5, 2018 Category: ENT & OMF Source Type: research

Calculation of indirect costs of associated with postoperative caregiver absences after pediatric tonsil surgery
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 5, 2018 Category: ENT & OMF Source Type: research

Professor Emeritus, Dr. Med. Mirko Tos
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 5, 2018 Category: ENT & OMF Source Type: research

Incomplete and false tract insertions in cochlear implantation: retrospective review of surgical and auditory outcomes
ConclusionsIEI during cochlear implantation using straight electrodes can occur with or without cochlear luminal obstruction. Age plays an important role in the auditory rehabilitation in this patient subset. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 5, 2018 Category: ENT & OMF Source Type: research

Sinonasal seromucinous hamartoma
ConclusionSinonasal SH is a rare diagnosis characterized by a polypoid lesion with a haphazard proliferation of seromucinous glands. The rhinologists should consider it in the differential diagnosis of a polypoid lesion in the nasal cavity. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 16, 2018 Category: ENT & OMF Source Type: research

Letter to the editor on “Are the Epworth Sleepiness Scale and Stop-Bang model effective at predicting the severity of obstructive sleep apnoea (OSA); in particular OSA requiring treatment?”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 16, 2018 Category: ENT & OMF Source Type: research

Indicators for imaging in periorbital cellulitis secondary to rhinosinusitis
AbstractPurposeOur objective was to identify the clinical indicators for subperiosteal orbital abscess (SPOA) among patients who present with periorbital cellulitis secondary to rhinosinusitis, and to evaluate the need for performing a computerized tomography (CT) scan.MethodsA retrospective cohort study of all patients admitted to our tertiary care emergency department between 2006 and 2014 was conducted. Included were healthy patients with acute periorbital cellulitis secondary to rhinosinusitis. Variables analyzed included age, gender, duration of symptoms, previous antibiotic therapy, highest recorded temperature, phys...
Source: European Archives of Oto-Rhino-Laryngology - February 15, 2018 Category: ENT & OMF Source Type: research

Prognostic value of age, subglottic, and anterior commissure involvement for early glottic carcinoma treated with CO 2 laser transoral microsurgery: a retrospective, single-center cohort study of 261 patients
Conclusions CO2 laser transoral microsurgery is an effective and reproducible single-stage modality therapy for young and elderly patients with glottic carcinoma. Superficial close margins can be managed by a careful wait-and-see policy, while positive margins should undergo surgical enlargement. In our experience, undifferentiated tumors, true subglottic extension, and anterior commissure involvement of grade 3 were associated with worse outcomes. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 13, 2018 Category: ENT & OMF Source Type: research

A comparison of Dysphonia Severity Index and Acoustic Voice Quality Index measures in differentiating normal and dysphonic voices
AbstractPurposeThe aim of the study was to investigate and compare the feasibility and robustness of the Acoustic Voice Quality Index (AVQI) and the Dysphonia Severity Index (DSI) in diagnostic accuracy, differentiating normal and dysphonic voices.MethodsA group of 264 subjects with normal voices (n = 105) and with various voice disorders (n = 159) were asked to read aloud a text and to sustain the vowel /a/. Both speech tasks were concatenated, and perceptually rated for dysphonia severity by five voice clinicians. They rated the Grade (G) and the overall dysphonia severity with a visual analog...
Source: European Archives of Oto-Rhino-Laryngology - February 13, 2018 Category: ENT & OMF Source Type: research

Diagnostic flexible pharyngo-laryngoscopy: development of a procedure specific assessment tool using a Delphi methodology
ConclusionThe gathering of validity evidence for assessment of core procedural skills within Otorhinolaryngology is central to the development of a competence-based education. The use of an international Delphi panel allows for the creation of an assessment tool which is widely applicable and valid. This work allows for an informed approach to technical skills training for flexible pharyngo-laryngoscopy and as further validity evidence is gathered allows for a valid assessment of clinical performance within this important skillset. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 13, 2018 Category: ENT & OMF Source Type: research

Accuracy and feasibility of a dedicated image guidance solution for endoscopic lateral skull base surgery
ConclusionsUseful surgical navigation is, to a large extent, a result of sufficiently accurate tracking technology. We have demonstrated sufficient accuracy and a potentially suitable integration for surgical application within endoscopic lateral skull base procedures. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 13, 2018 Category: ENT & OMF Source Type: research

Innovative real CSF leak simulation model for rhinology training: human cadaveric design
ConclusionThe design is simulating the real patient with CSF leak. It has potential in the learning process of acquiring and maintaining the surgical skills of skull base reconstruction before direct involvement of the patient. This model needs further evaluation and competence measurement as training tools in rhinology training. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2018 Category: ENT & OMF Source Type: research

Non-enhanced MRI in combination with color Doppler flow imaging for improving diagnostic accuracy of parotid gland lesions
ConclusionCombining CDFI with non-enhanced MRI can improve the diagnostic accuracy of MRI for classifying parotid gland lesions. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2018 Category: ENT & OMF Source Type: research

Risk factors for complications in cochlear implant surgery
ConclusionsThe use of a strict definition of a medical complication and device failure —in combination with the Clavien–Dindo classification system—enables uniform and objective registration of adverse events and prevents any tendency to downgrade complications. Complication and failure rates in this series are comparable to those reported in the literature. These results stress the need for pneumococcal vaccination, which may prevent general wound infections, but is especially important for patients with inner ear malformation, who have an increased risk of (postoperative) meningitis. (Source: European A...
Source: European Archives of Oto-Rhino-Laryngology - February 10, 2018 Category: ENT & OMF Source Type: research

Middle ear microvascularization: an “in vivo” endoscopic anatomical study
ConclusionThe vascular anatomy and BFD of the medial wall of the tympanic cavity can be easily studied in transcanal endoscopy. ITA (with a superior BFD in most cases) and ISA (with a main BFD from the incus to the stapes) are the most constant identifiable vessels. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 10, 2018 Category: ENT & OMF Source Type: research

Evaluation of the success of obstructive sleep apnea surgery using criteria based on long-term symptoms and incident hypertension
ConclusionsOur results suggest that some of the success criteria analyzed may be more useful in differentiating between success and failure groups after surgery, in terms of long-term improvement of subjective OSA-related symptoms. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 8, 2018 Category: ENT & OMF Source Type: research

Swallowing evaluation after surgery for obstructive sleep apnea syndrome: uvulopalatopharyngoplasty vs. expansion pharyngoplasty
ConclusionsOSAS patients show sub-clinical changes in swallowing pattern before surgery. Both surgical techniques are related to transitory changes in swallowing biomechanics. Complete or partial reversal to pre-operative swallowing parameters occurs 1  month after both surgery techniques. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 8, 2018 Category: ENT & OMF Source Type: research

Relationship between swallowing-related quality of life and fiberoptic endoscopic evaluation of swallowing in patients who underwent open partial horizontal laryngectomy
ConclusionsInvestigating patients ’ perception of swallowing impairment and swallowing-related QOL is not sufficient to discriminate safe and unsafe swallowing in OPHL patients. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 8, 2018 Category: ENT & OMF Source Type: research

Acknowledgement to referees 2017
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 8, 2018 Category: ENT & OMF Source Type: research