Implementation of the European Laryngological Society classification for pediatric benign laryngotracheal stenosis: a multicentric study
AbstractPurposeThe European Laryngological Society (ELS) has published a revised classification for benign laryngotracheal stenosis (LTS), based on their degree, longitudinal extension, and associated comorbidities. We retrospectively applied this classification to pediatric patients treated in four referral centers to assess its reliability in predicting surgical outcomes.MethodsWe included 191 pediatric LTS patients treated by segmental resection, restaged according to the degree of stenosis (I –IV according to Myer–Cotton grading system), number of subsites involved (“a” to “d” for 1&...
Source: European Archives of Oto-Rhino-Laryngology - February 22, 2019 Category: ENT & OMF Source Type: research

Budesonide nasal irrigation improved Lund –Kennedy endoscopic score of chronic rhinosinusitis patients after endoscopic sinus surgery
ConclusionsNasal irrigation improved the prognosis of CRS patients after ESS. Budesonide nasal irrigation had a better effect than normal saline nasal irrigation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 20, 2019 Category: ENT & OMF Source Type: research

Correction to: Clinical manifestations of hydropic ear disease (Meni ère’s)
In the original publication, Fig.  1 was incorrectly published with incomplete legends. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 18, 2019 Category: ENT & OMF Source Type: research

Influence of external ear occlusion on food perception
ConclusionPlugging the ear canals led to increased mastication sound levels. Participants did not seem to consider these additional acoustic cues when they rated food freshness, food appreciation, and willingness of eating the specific food. Only men seemed to take these cues into account when they rated their habit consumption of soft food. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 18, 2019 Category: ENT & OMF Source Type: research

Nasal response to stress test in healthy subjects: an experimental pilot study
ConclusionWe observed that stress influenced the feeling of nasal patency in healthy subjects. However, the objective effects of stress on nasal geometry were globally non-significant except in “weakly anxious” group. This latter result of our pilot study needs to be confirmed in a larger cohort. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 15, 2019 Category: ENT & OMF Source Type: research

Effects of electromyographic biofeedback as an adjunctive therapy in the treatment of swallowing disorders: a systematic review of the literature
ConclusionsAdjunctive therapeutic protocols with biofeedback electromyography exert positive effects on swallowing function. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 15, 2019 Category: ENT & OMF Source Type: research

Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a oral spray for children with recurrent streptococcal pharyngotonsillitis: a randomized placebo-controlled clinical study
ConclusionsWe identified potential probiotics, possessing desirable features against GABHS pharyngotonsillitis. Our findings represent the first evidence which throws the light on using these probiotics that can reduce antibiotics use which did not have efficient results regarding recurrence. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 15, 2019 Category: ENT & OMF Source Type: research

A reliable method to avoid contamination during cartilage graft preparation in septorhinoplasty
AbstractPurposeThe aim of the study is to determine the risk of contamination in the cartilage graft materials prepared on the swester table and those prepared in a sterile package, and to reveal a more reliable method by performing the microbiological examination of these materials.MethodsCartilages removed from the nasal septum were divided into four pieces. The first part (Sample A) was directly placed into the medium. Sample B was prepared by being crushed in a sterile package. Sample C was prepared on the auxiliary swester table, and Sample D was prepared on the main swester table actively used by surgery team. All sa...
Source: European Archives of Oto-Rhino-Laryngology - February 15, 2019 Category: ENT & OMF Source Type: research

Ossicular chain erosion in chronic otitis media patients with cholesteatoma or granulation tissue or without those: analysis of 915 cases
ConclusionThe most commonly seen OCE was incus erosion, followed by stapes and malleus erosions. The results of this study show that there are more OCE in the COM-C group than in the COM-G and COM groups. To our knowledge, this study has the widest patient population in the literature focused on the OCE relation with COM, COM-C, and COM-G and its effect on the preoperative hearing level. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 13, 2019 Category: ENT & OMF Source Type: research

FDG-PET/CT improves detection of residual disease and reduces the need for examination under anaesthesia in oropharyngeal cancer patients treated with (chemo-)radiation
AbstractPurposeEarly detection of residual disease (RD) after (chemo)radiation for oropharyngeal (OPC) is crucial. Surveillance of neck nodes with FDG-PET/CT has been studied extensively, whereas its value for local RD remains less clear. We aim to evaluate the diagnostic value of post-treatment FDG-PET/CT in detecting local RD and the outcome of patients with local RD.MethodsA cohort (n = 352) of consecutively treated OPC patients at our institute between 2010 and 2017 was evaluated. Patients that underwent FDG-PET/CT at 3 months post-treatment (n = 94) were classified as having complete (CMR) ...
Source: European Archives of Oto-Rhino-Laryngology - February 13, 2019 Category: ENT & OMF Source Type: research

Contribution of Nitric oxide synthase 3 genetic variants to nasopharyngeal carcinoma risk and progression in a Tunisian population
ConclusionsThis is the first study to associate NPC with significantly higher levels of plasma NO. NOS3-derived NO could play key roles in NPC pathogenesis. NOS3 variants differently contribute to NPC risk and progression in a Tunisian population. NOS3 G894T was associated with NPC risk. NOS3 T-786C decreased the levels of plasma NO and reduced the development of regional lymph node metastasis. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 13, 2019 Category: ENT & OMF Source Type: research

Roles of Ki-67 and p16 as biomarkers for unknown primary head and neck squamous cell carcinoma
ConclusionsThe combination of ki67 expression and p16 expression status may allow prediction of local control more accurately than p16 expression status alone. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2019 Category: ENT & OMF Source Type: research

The anatomical and radiological evaluation of the Vidian canal on cone-beam computed tomography images
ConclusionsOur results may assist with proper treatment for surgical procedures around the Vidian canal with a high success rate and minimal complications. Therefore, the results obtained in this study contribute to the literature. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2019 Category: ENT & OMF Source Type: research

Safety of outpatient admission and comparison of different surgical techniques in adult tonsillectomy
AbstractPurposeTo investigate the safety of outpatient admission and the effects of surgical technique in tonsillectomy operations of adult patients.MethodsThe digital database was scanned for patients aged ≥ 15 years that underwent tonsillectomy in our institution between years 2014 and 2018. Demographic and clinical characteristics, the surgical technique, length of stay (LOS) in hospital, re-admissions after discharge, complications and interventions performed were recorded.ResultsA total of 276 patients met the inclusion criteria, comprising 139 (50.4%) females and 137 (49.6%) males with a mean age of 27...
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2019 Category: ENT & OMF Source Type: research

Extension patterns of vestibular schwannomas towards the middle ear: three new cases and review of the literature
We report three new cases of vestibular schwannomas extending to the middle ear and reviewed the literature to specify the patterns of such an extension.Materials and methodsWe analysed databases of previously published articles to search for additional cases of middle ear extension of vestibular schwannomas and compared them to the cases we have documented. Extension patterns of the tumours were analysed, especially focusing on the extension through the round and oval windows.Results and conclusionMiddle ear vestibular schwannomas are uncommon tumours and only 13 cases have been published so far. The vestibular schwannoma...
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2019 Category: ENT & OMF Source Type: research

The microRNA-375 as a potentially promising biomarker to predict the prognosis of patients with head and neck or esophageal squamous cell carcinoma: a meta-analysis
This study was performed to investigate the prognostic significance of miR-375 expression in SCC based on all eligible evidences.MethodsRelevant studies were identified by searching PubMed, Embace, Medline, Cochrane Library, and China Biology Medicine disk. Survival outcome including overall survival (OS) and other survival outcomes were used as the primary endpoint to evaluate the prognostic outcome of patients with SCC. All statistical analyses were performed in RevMan software version 5.3 and STATA software version 14.1. Furthermore, the quality of included studies was assessed by The Newcastle –Ottawa Scale.Resul...
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2019 Category: ENT & OMF Source Type: research

Post-contrast 3D-FLAIR in idiopathic sudden sensorineural hearing loss
ConclusionsPost-contrast 3D-FLAIR after intravenous Gd injection in SSNHL can be used to assess the permeability of the blood –labyrinth and blood–nerve barriers. The asymmetry ratios of the inner ear structures may identify patients with poor prognosis for hearing recovery. Signal characteristics are closely related to interval time between onset and MRI. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 12, 2019 Category: ENT & OMF Source Type: research

Does procalcitonin have a role in the pathogenesis of nasal polyp?
ConclusionsThis is the first study of its kind to objectively examine PCT in the polyp and serum of CRSwNP patients. PCT may serve as a diagnostic biomarker in nasal polyps. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 9, 2019 Category: ENT & OMF Source Type: research

The SNOT-22 factorial structure in European patients with chronic rhinosinusitis: new clinical insights
This study thus sought to address these issues.MethodsPrincipal component analysis and confirmatory factor analysis were performed from SNOT-22 questionnaires completed by European CRS patients. Goodness of fit, internal consistencies, and factor loadings were calculated. Item-domain assignment was based on statistical grounds and clinical meaningfulness. Additionally, this study investigated correlations between SNOT-22 domains and external reference criteria, including Lund –Mackay score, Lund–Naclerio score and the brief symptom inventory 18 (BSI-18).ResultsOne hundred and thirty-four European CRS patients w...
Source: European Archives of Oto-Rhino-Laryngology - February 9, 2019 Category: ENT & OMF Source Type: research

Robotic cochlear implantation: feasibility of a multiport approach in an ex vivo model
ConclusionsElectrode insertion through a robotic three-port approach is feasible. Drill tunnels through the facial recess for the electrode and endoscope allow for optimized insertion angles and sufficient visualization. Through a retrofacial tunnel effective manipulation for sealing is possible. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 9, 2019 Category: ENT & OMF Source Type: research

Drop attacks, hydrops severity, and disease duration in hydropic ear disease (Meni ère’s)
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 9, 2019 Category: ENT & OMF Source Type: research

Ectoine lozenges in the treatment of acute viral pharyngitis: a prospective, active-controlled clinical study
This study compared lozenges containing ectoine, a natural extremolyte, with hyaluronic acid lozenges and hypertonic saline gargle for symptomatic treatment of acute viral pharyngitis.MethodsThis prospective, controlled clinical study, recruited 90 patients with moderate-to-severe pharyngitis symptoms who chose to use either ectoine (n = 35), hyaluronic acid (n = 35), or saline gargle (n = 20). Patients applied their 7-day treatment from the inclusion visit (V1) until the end-of-study visit (V2). Patients’ pharyngitis symptoms, general health, general treatment effectiveness ...
Source: European Archives of Oto-Rhino-Laryngology - February 9, 2019 Category: ENT & OMF Source Type: research

The prevalence of hearing loss and use of hearing aids among adults in Germany: a systematic review
DiscussionThe present review demonstrates clearly that evidence-based information relating to Germany can only be made on the basis of a clear definition of hearing loss within the framework of an up-to-date and representative epidemiological study carried out with appropriate methodology. In view of the high prevalence of illnesses causing hearing impairment and of the risks to health associated with untreated hearing impairment as well as of socio-economic costs, such an epidemiological study is of great social significance. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 9, 2019 Category: ENT & OMF Source Type: research

Oral cancer of Sigmund Freud
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 8, 2019 Category: ENT & OMF Source Type: research

Rising incidences of Warthin ’s tumors may be linked to obesity: a single-institutional experience
AbstractPurposeRecently, there has been an increase in the number of reported Warthin ’s tumors, but few risk factors have been described for this benign tumor. Yet, smoking is the only evidently identified risk factor. Obesity and the metabolic syndrome are causally linked to or a risk factor for a variety of diseases. Therefore, we analyzed whether metabolic syndrome, including o besity, might influence the incidence of Warthin’s tumors.MethodsIn this retrospective study, we evaluated 197 patients with Warthin ’s tumor. We assessed the tumor size, the body mass index (BMI), comorbidities related to the ...
Source: European Archives of Oto-Rhino-Laryngology - February 7, 2019 Category: ENT & OMF Source Type: research

Management of clinically N0 neck in oropharyngeal carcinoma
ConclusionsWhile the overall prognosis of OPSCC is generally favorable and regional recurrences are infrequent, soft palate tumors, that are usually p16 negative, may form an subgroup warranting more aggressive treatment despite the clinical appearance of early stage. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 7, 2019 Category: ENT & OMF Source Type: research

An investigation of oxidative stress and coenzyme Q10 levels in patients with head and neck squamous cell carcinomas
AbstractObjectiveThe purpose of this study was to determine the oxidative states of head and neck squamous cell carcinoma (HNSCC) patients by measuring their plasma levels of malondialdehyde (MDA), an indicator of lipid peroxidation, 3-nitrotyrosine (3-NT), an indicator of protein oxidation, and the coenzyme Q10 (CoQ10), an important antioxidant, and compare them with healthy individuals.Materials and methodsThe plasma MDA, 3-NT and CoQ10 levels of 35 patients and 20 healthy individuals were measured with the high-performance liquid chromatography (HPLC) method. By comparing the patients ’ smoking habits, stage of th...
Source: European Archives of Oto-Rhino-Laryngology - February 7, 2019 Category: ENT & OMF Source Type: research

Pediatric otogenic lateral sinus thrombosis: focus on the prognostic role of contralateral venous drainage
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 6, 2019 Category: ENT & OMF Source Type: research

Tumor volume as a predictive parameter in the sequential therapy (induction chemotherapy) of head and neck squamous cell carcinomas
ConclusionThe initial tumor volume had no influence on CR, OS or DFS. A severe response to ICT did not predict a powerful RCT outcome. The change in tumor volume post-RCT had an impact on OS and DFS. Tumor volume estimation using its diameter seems to be a reliable method. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 6, 2019 Category: ENT & OMF Source Type: research

Malformations of the lateral semicircular canal correlated with data from the audiogram
ConclusionLSCC malformations are commonly associated with hearing loss (61%), especially SHNL (39%). The high rate (81%) of contralateral hearing disturbances in unilateral LSCC malformations should be taken into account in the patient ’s daily life to avoid triggering or exacerbating any hearing loss. Otologists and radiologists must cooperate to ensure that all malformations are correctly described on CT, especially to improve the patient’s education regarding hearing preservation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 6, 2019 Category: ENT & OMF Source Type: research

Acknowledgements to referees 2018
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 5, 2019 Category: ENT & OMF Source Type: research

Severe deviated nose treatment: importance of preserving the dorsal septal remnant
ConclusionBoth methods are effective in patients with a severely deviated nose for correction of deviation and obstruction. Anterior septal reconstruction is the preferable method in patients with more deviation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - February 2, 2019 Category: ENT & OMF Source Type: research

Comparative prognosis in patients with Ramsay-Hunt syndrome and Bell ’s palsy
AbstractPurposePatients with Ramsay-Hunt syndrome have a poorer prognosis than patients with Bell ’s palsy. Factors of metabolic syndrome affecting prognosis were therefore compared between patients with Ramsay-Hunt syndrome and those with Bell’s palsy.MethodsThis retrospective study included 106 with Ramsay-Hunt syndrome and 182 with Bell ’s palsy. Age, sex, body mass index, blood pressure, blood test results, and ENoG results, stratified by House–Brackmann grade, were compared in patients with Ramsay-Hunt syndrome and Bell’s palsy. Both groups of patients were treated with steroids and the a...
Source: European Archives of Oto-Rhino-Laryngology - February 1, 2019 Category: ENT & OMF Source Type: research

Prof. Heinz Stammberger, MD (Hon. FRCS (Ed.), Hon. FRCS (Engl.), Hon. FACS) December 1st 1946 –December 9th 2018
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 31, 2019 Category: ENT & OMF Source Type: research

Syndromes that predispose to epistaxis
Discussion and conclusionSince a number of these syndromes are rare and elaborate tests are not carried out in the absence of a positive family history or until other specific clinical features appear, a risk of underdiagnosis and the dilemma of whether epistaxis is specifically related to the syndrome or a secondary effect still remains. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 30, 2019 Category: ENT & OMF Source Type: research

Consequences of hearing aid acclimatization on ALLRs and its relationship with perceived benefit and speech perception abilities
ConclusionsThe study provides evidence for improvements in neural processing of auditory cortical areas with hearing aid acclimatization. The improvements seen in perceived benefit and speech perception are not related to the improvements in ALLRs. This is the first study in the domain with a younger group compared to the previous studies and the results show evidence for neural plasticity influencing hearing aid acclimatization benefits. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 29, 2019 Category: ENT & OMF Source Type: research

Quantitative evaluation of endolymphatic hydrops with MRI through intravenous gadolinium administration and VEMP in unilateral definite Meniere ’s disease
AbstractPurposeTo help clinicians to further understand the significance of vestibular-evoked myogenic potential (VEMP) examinations to diagnose MD and the quantitative relationship between VEMP and MRI in assessing the location and degree of endolymphatic hydrops (EH) in definite Meniere ’s disease (MD) patients.MethodsFifty-six patients with unilateral definite MD participated in this study, which used MRIs through intravenous gadolinium administration (IV-Gd), audiometry, caloric tests and VEMP tests. The VEMP results of 26 healthy volunteers were used as a normal reference value.ResultsThe participants were found...
Source: European Archives of Oto-Rhino-Laryngology - January 29, 2019 Category: ENT & OMF Source Type: research

Diagnosis and treatment choices of suspected benign paroxysmal positional vertigo: current approach of general practitioners, neurologists, and ENT physicians
ConclusionsA significant proportion of Lithuanian neurologists, ENT physicians, and GPs do not employ diagnostic maneuvers and CRPs for BPPV patients, contrary to established guidelines. Lack of expertise and time available is a common culprit that leads to unnecessary drug prescribing and investigation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 29, 2019 Category: ENT & OMF Source Type: research

Development of a standardized evaluation of endobuccal adverse events induced by repeated tongue protrusion with both a dedicated questionnaire and an endobuccal examination
ConclusionThe TAESQ, ELE and ERFE have been designed and studied on a small number of participants. These evaluations could systematically be included in the care pathway of patients treated by UAS to better investigate tongue discomfort and tongue lesion for patients treated with this technology. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 28, 2019 Category: ENT & OMF Source Type: research

Outcomes of endoscopic sinus surgery in adult lung transplant patients with cystic fibrosis
ConclusionsESS represents the best option to improve clinical QoL of CF patients who do not response to conventional medical therapy, with a stabilization of respiratory function after transplantation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 28, 2019 Category: ENT & OMF Source Type: research

Interobserver agreement of skeletal muscle mass measurement on head and neck CT imaging at the level of the third cervical vertebra
The objective of this study was to assess the robustness of this novel C3 measurement method in terms of interobserver agreement.Patients and methodsPatients diagnosed with locally advanced head and neck squamous cell carcinoma (LA-HNSCC) at our center between 2007 and 2011 were evaluated. Fifty-four patients with were randomly selected for analysis. Six observers independently measured the cross-sectional muscle area (CSMA) at the level of C3 using a predefined, written protocol as instruction. Interobserver agreement was assessed using intraclass correlation coefficients (ICCs), a Bland –Altman plot and Fleiss&rsqu...
Source: European Archives of Oto-Rhino-Laryngology - January 28, 2019 Category: ENT & OMF Source Type: research

Obstructive sleep apnea in children and adolescents with and without obesity
AbstractPurposeTo investigate the prevalence of obstructive sleep apnea (OSA) in children referred for obesity treatment, and to compare the prevalence with that of a normal-weight group. Moreover, we examined the association between Body Mass Index Standard Deviation Score (BMI SDS) and the Apnea –Hypopnea Index (AHI).MethodsThis cross-sectional study included 139 children aged 7 –18 years with overweight/obesity (BMI SDS >1.28) recruited from an obesity treatment clinic. The normal-weight group consisted of 33 children (BMI SDS  ≤ 1.28) aged 7–18 years recruited from...
Source: European Archives of Oto-Rhino-Laryngology - January 28, 2019 Category: ENT & OMF Source Type: research

The effectiveness of high-resolution ultrasound in the assessment of the carotid intima –media thickness for postirradiated neck
ConclusionMeasurement of the mean CIMT using ultrasound could be useful for assessing CVD risk in HNC survivors after neck irradiation. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 25, 2019 Category: ENT & OMF Source Type: research

Otolaryngologists adhere to evidence-based guidelines for chronic rhinosinusitis
ConclusionsOverall, both the EPOS and CBO guideline are well known among Dutch Otolaryngologists and 90% indicates that the guideline is important in their daily practice. Adherence to the guidelines is sufficient to high. If multiple treatment or diagnostic options are recommended this leads to a more heterogeneous response pattern. Recommendations with a high grade of recommendation were followed up most often. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 25, 2019 Category: ENT & OMF Source Type: research

A comparison between collaborative and single surgeon approach in endoscopic endonasal surgery to sphenoid sinus
AbstractPurposeEndoscopic endonasal transsphenoidal surgery (EETS) requires abundant collaborative work between neurosurgeon and ear, nose, and throat (ENT) surgeon. In low-volume centers, however, the surgery may be carried out completely and solely by a neurosurgeon. The current study evaluates the differences in both technique and complications in the approach to the sphenoid sinus for endoscopic endonasal approach (EEA) performed solely by a single neurosurgeon compared to collaborative effort between neurosurgery and otolaryngology.MethodsThe study comprises 50 consecutive patients with intra-sellar pituitary lesions ...
Source: European Archives of Oto-Rhino-Laryngology - January 24, 2019 Category: ENT & OMF Source Type: research

Decreased Treg-derived miR-181a and miR-155 correlated with reduced number and function of Treg cells in allergic rhinitis children
ConclusionDecreased Treg-derived miR-181a and miR-155 were correlated with reduced number and function of Tregs in AR children. The intracellular miR-155 and miR-181a levels may serve as predictors of disease severity in childhood AR. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 23, 2019 Category: ENT & OMF Source Type: research

Salvage surgery for advanced stage head and neck squamous cell carcinoma following radiotherapy or chemoradiation
ConclusionsSalvage surgery for recurrent advanced stage head and neck squamous cell carcinoma after primary (chemo)radiotherapy is a good last resort curative treatment option, resulting in 37% overall survival at 5 years. As data from advanced stage non-laryngeal tumors were sparse, no solid conclusions can be drawn with regard to outcome differences between tumor subsites. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 23, 2019 Category: ENT & OMF Source Type: research

Acute invasive fungal rhinosinusitis: our 2  year experience and outcome analysis
ConclusionA high index of suspicion, awareness among medical fraternity and precise sample collection aids a firm diagnosis. Simultaneous initiation of surgical debridement and anti-fungals is fundamental. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 22, 2019 Category: ENT & OMF Source Type: research

Is intensity-modulated radiotherapy superior to conventional techniques to prevent late ear complications of nasopharyngeal cancer?
This study analyzed the late ear complications of radiotherapy for nasopharyngeal cancer  (NPC) and compared the conventional and intensity-modulated radiotherapy (2D-RT and IMRT, respectively).MethodsAt 2 –21 years after the end of NPC treatment, 104 ears of 52 patients were evaluated with the otoscopic examination, pure tone audiometry test, tympanometry, and subjective complaints by being blinded to the radiotherapy technique.ResultsThere were no differences in terms of the pathology of the external, middle or inner ear, air and bone-conduction hearing thresholds, and the air –bone (A–B) gap ...
Source: European Archives of Oto-Rhino-Laryngology - January 22, 2019 Category: ENT & OMF Source Type: research

Correlation between the duration of locoregional control and survival in T1 –T2 oropharyngeal cancer patients
AbstractPurposeTo investigate the correlation between the time to locoregional recurrence and survival in T1 –T2 oropharyngeal squamous-cell carcinoma (OPSCC) patients.MethodsA retrospective, single-site study of patients with T1 –T2 OPSCC treated with curative intent between 2000 and 2015 who had a locoregional recurrence without distant metastases. Patients without a disease-free interval (i.e., persistent macroscopic disease after the end of treatment and a time to locoregional recurrence of less than 3 months) were exc luded. The endpoint considered was overall survival (OS).ResultsOut of 602 T1 –T2 O...
Source: European Archives of Oto-Rhino-Laryngology - January 21, 2019 Category: ENT & OMF Source Type: research