Significant risk of second primary cancer among laryngeal squamous cell carcinoma patients even after 20 years
Conclusion: Patients with LSCC as primary cancer have a 60% excess risk for an SPC, especially for tobacco-associated cancers, remaining significantly elevated even decades after treatment.PMID:37672344 | DOI:10.1080/0284186X.2023.2254482 (Source: Acta Oncologica)
Source: Acta Oncologica - September 6, 2023 Category: Cancer & Oncology Authors: Rayan Nikkil ä Elli Hirvonen Aaro Haapaniemi Laura Tapiovaara Janne Pitk äniemi Nea Malila Antti M äkitie Source Type: research

Significant risk of second primary cancer among laryngeal squamous cell carcinoma patients even after 20 years
Conclusion: Patients with LSCC as primary cancer have a 60% excess risk for an SPC, especially for tobacco-associated cancers, remaining significantly elevated even decades after treatment.PMID:37672344 | DOI:10.1080/0284186X.2023.2254482 (Source: Acta Oncologica)
Source: Acta Oncologica - September 6, 2023 Category: Cancer & Oncology Authors: Rayan Nikkil ä Elli Hirvonen Aaro Haapaniemi Laura Tapiovaara Janne Pitk äniemi Nea Malila Antti M äkitie Source Type: research

Pedicled thoracoacromial artery compound flaps for circumferential hypopharyngeal reconstruction
ConclusionsThe pedicled thoracoacromial artery compound flaps have stable blood supply and provide adequate muscle coverage for greater protection during radiotherapy, and the microsurgical skills have no requirement. Therefore, the compound flaps provide a good choice for the reconstruction of circumferential hypopharyngeal defect, especially in the aged or patients with comorbidities who are not able to tolerate prolonged surgery. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 5, 2023 Category: ENT & OMF Source Type: research

Development of programs to predict the occurrence of mucositis from digital imaging and communications in medicine data by machine learning in head and neck volumetric modulated radiotherapy
This study aimed to develop a machine learning program that can predict the development of mucositis requiring ART. This study included 61 patients who received concurrent chemotherapy and radiotherapy (RT). For each patient, the equivalent square field size of each segmental irradiation field used for VMAT, dose per segment (Gy), clinical target volume high, and mean dose of the oral cavity (Gy) were calculated. Furthermore, 671 five-dimensional lists were generated from the acquired data. Support vector machine (SVM) and K-nearest neighbor (KNN) were used for machine learning. For the accuracy score, the test size was va...
Source: Journal of Applied Clinical Medical Physics - August 21, 2023 Category: Physics Authors: Toshiya Rachi Takaki Ariji Shinichi Takahashi Source Type: research

Development of programs to predict the occurrence of mucositis from digital imaging and communications in medicine data by machine learning in head and neck volumetric modulated radiotherapy
This study aimed to develop a machine learning program that can predict the development of mucositis requiring ART. This study included 61 patients who received concurrent chemotherapy and radiotherapy (RT). For each patient, the equivalent square field size of each segmental irradiation field used for VMAT, dose per segment (Gy), clinical target volume high, and mean dose of the oral cavity (Gy) were calculated. Furthermore, 671 five-dimensional lists were generated from the acquired data. Support vector machine (SVM) and K-nearest neighbor (KNN) were used for machine learning. For the accuracy score, the test size was va...
Source: Journal of Applied Clinical Medical Physics - August 21, 2023 Category: Physics Authors: Toshiya Rachi Takaki Ariji Shinichi Takahashi Source Type: research

Economical Evaluation of Cancer Types Using Intensity-Modulated Radiation Therapy Compared to 3D Conformal Radiation Therapy: A Systematic Review
CONCLUSION: The results can help to decide whether to use radiation therapy and radiotherapy in the standard treatment path. Furthermore, they underline that IMRT treatment technique was cost effective for a long-time care service.PMID:37593521 | PMC:PMC10430406 | DOI:10.18502/ijph.v52i7.13237 (Source: Cancer Control)
Source: Cancer Control - August 18, 2023 Category: Cancer & Oncology Authors: Vahid Alipour Aziz Rezapour Amin Adel Arefeh Pourtaleb Mitra Bazrafshan Mozhgan Sadat Ghaem Mohammadi Reza Jahangiri Source Type: research

Analysis of the anatomical distribution of HPV genotypes in head and neck squamous papillomas
by Huiying Hu, Huanyu Jiang, Zhenwen Zhu, Honglin Yin, Kai Liu, Lijuan Chen, Mengyuan Zhao, Zhenkun Yu Squamous papillomas (SPs) of the head and neck are usually benign lesions associated with human papilloma virus (HPV) infection. However, the reported HPV detection rates vary widely, especially with respect to anatomical distribution. The etiology of SPs in the head and neck remains unclear; anal yzing HPV genotypes of SPs based on anatomical sites could assist in clarifying the pathogenesis of SPs in the head and neck. Therefore, the aim of this study was to review the prevalence, subtypes, and anatomical distribution ...
Source: PLoS One - August 11, 2023 Category: Biomedical Science Authors: Huiying Hu Source Type: research

Characteristics and predictors associated with cancer-related fatigue among solid and liquid tumors
CONCLUSION: This study provided an effective platform to assess potential risks and outcomes of CRF in patients hospitalized for the management of solid and non-solid tumors. Our study showed ML methods performed well in predicting the CRF among solid and liquid tumors.PMID:37540252 | DOI:10.1007/s00432-023-05197-w (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - August 4, 2023 Category: Cancer & Oncology Authors: Poolakkad S Satheeshkumar Roberto Pili Joel B Epstein Sudheer B Kurunthatil Thazhe Rhine Sukumar Minu Ponnamma Mohan Source Type: research

Characteristics and predictors associated with cancer-related fatigue among solid and liquid tumors
CONCLUSION: This study provided an effective platform to assess potential risks and outcomes of CRF in patients hospitalized for the management of solid and non-solid tumors. Our study showed ML methods performed well in predicting the CRF among solid and liquid tumors.PMID:37540252 | DOI:10.1007/s00432-023-05197-w (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - August 4, 2023 Category: Cancer & Oncology Authors: Poolakkad S Satheeshkumar Roberto Pili Joel B Epstein Sudheer B Kurunthatil Thazhe Rhine Sukumar Minu Ponnamma Mohan Source Type: research

Characteristics and predictors associated with cancer-related fatigue among solid and liquid tumors
CONCLUSION: This study provided an effective platform to assess potential risks and outcomes of CRF in patients hospitalized for the management of solid and non-solid tumors. Our study showed ML methods performed well in predicting the CRF among solid and liquid tumors.PMID:37540252 | DOI:10.1007/s00432-023-05197-w (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - August 4, 2023 Category: Cancer & Oncology Authors: Poolakkad S Satheeshkumar Roberto Pili Joel B Epstein Sudheer B Kurunthatil Thazhe Rhine Sukumar Minu Ponnamma Mohan Source Type: research

Disease burden, risk factors, and trends of lip, oral cavity, pharyngeal cancers: A global analysis
ConclusionsAlthough global incidence and mortality trends reported an overall decrease, significant increases were found for older age groups and female subjects. Incidence increase may be due to the growing prevalence of lifestyle, metabolic risk factors, and HPV infections, especially in developed countries. (Source: Cancer Medicine)
Source: Cancer Medicine - July 31, 2023 Category: Cancer & Oncology Authors: Junjie Huang, Sze Chai Chan, Samantha Ko, Veeleah Lok, Lin Zhang, Xu Lin, Don E. Lucero ‐Prisno, Wanghong Xu, Zhi‐Jie Zheng, Edmar Elcarte, Mellissa Withers, Martin C. S. Wong, NCD Global Health Research Group, Association of Pacific Rim U Tags: RESEARCH ARTICLE Source Type: research

Cancers, Vol. 15, Pages 3894: Mapping the Potential of Microfluidics in Early Diagnosis and Personalized Treatment of Head and Neck Cancers
n D. Tran Head and neck cancers (HNCs) account for ~4% of all cancers in North America and encompass cancers affecting the oral cavity, pharynx, larynx, sinuses, nasal cavity, and salivary glands. The anatomical complexity of the head and neck region, characterized by highly perfused and innervated structures, presents challenges in the early diagnosis and treatment of these cancers. The utilization of sub-microliter volumes and the unique phenomenon associated with microscale fluid dynamics have facilitated the development of microfluidic platforms for studying complex biological systems. The advent of on-chip microfl...
Source: Cancers - July 31, 2023 Category: Cancer & Oncology Authors: Sangeeth Pillai Jan C. Kwan Fares Yaziji Hanwen Yu Simon D. Tran Tags: Review Source Type: research

Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology
Curr Oncol. 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501.ABSTRACTHead and neck squamous cell carcinomas arise from the mucosal epithelium of the oral cavity (lips, buccal mucosa, anterior tongue, hard palate, floor of mouth, and retromolar trigone), nasopharynx, oropharynx (tonsils, base of tongue, soft palate, uvula, and posterior pharyngeal wall), hypopharynx, and larynx [...].PMID:37504361 | DOI:10.3390/curroncol30070501 (Source: Current Oncology)
Source: Current Oncology - July 28, 2023 Category: Cancer & Oncology Authors: Melissa Henry Source Type: research

Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology
Curr Oncol. 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501.ABSTRACTHead and neck squamous cell carcinomas arise from the mucosal epithelium of the oral cavity (lips, buccal mucosa, anterior tongue, hard palate, floor of mouth, and retromolar trigone), nasopharynx, oropharynx (tonsils, base of tongue, soft palate, uvula, and posterior pharyngeal wall), hypopharynx, and larynx [...].PMID:37504361 | PMC:PMC10378608 | DOI:10.3390/curroncol30070501 (Source: Current Oncology)
Source: Current Oncology - July 28, 2023 Category: Cancer & Oncology Authors: Melissa Henry Source Type: research