Water-soluble biopolymers calcium polymalate derived from fermentation broth of Aureobasidium pullulans markedly alleviates osteoporosis and fatigue
In this study, we isolated a natural soluble biopolymer, calcium polymalate (PMACa), from the fermentation broth of the fungus Aureobasidium pullulans, to investigate its potential as an anti-osteoporosis therapeutic agent. Characterization revealed that linear PMA-Ca chains juxtaposed to form a porous, rod-like state, in the presence of Ca2+. In vivo mouse models demonstrated that PMA-Ca significantly promoted the conversion of serum calcium into bone calcium, and stimulated bone growth and osteogenesis. Additionally, PMA-Ca alleviated exercise fatigue in mice by facilitating the removal of essential metabolites, such as ...
Source: International Journal of Biological Macromolecules - May 2, 2024 Category: Biochemistry Authors: Fulin Li Xin Xie Xingran Xu Xiang Zou Source Type: research
Probiotics for Inflammatory Bowel Disease; A Deep Dive into Their Impact on Disease Course and Associated Health Risks
In conclusion, we recommend probiotics as an adjuvant therapeutic option for IBD therapy for ulcerative colitis; however, their role in Crohn's disease needs further research.PMID:38693730 | DOI:10.2174/0109298673314861240429072352 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - May 2, 2024 Category: Chemistry Authors: Wassan Nori Mohammed Hassan Methaq Mueen Al-Kaabi Nabeeha Najatee Akram Mustafa Ali Kassim Kassim Alexandru Cosmin Pantazi Source Type: research
Decompressive craniectomy surgery in a dog with intracranial extradural hematoma following blunt force trauma
This report describes the diagnosis and surgical management of an intracranial extradural hematoma in a dog with increased intracranial pressure refractory to medical management. Furthermore, this report describes the diagnostic imaging findings used to diagnose this particular form of primary brain injury.PMID:38694740 | PMC:PMC11017925 (Source: The Canadian Veterinary Journal)
Source: The Canadian Veterinary Journal - May 2, 2024 Category: Veterinary Research Authors: Ciaran C O'Carroll Bryan T Welch Meagan A Walker Adam T Ogilvie Lorrie Gaschen Katie L Hoddinott Source Type: research
Spinopelvic interactions in total hip arthroplasty: 295 patients followed for a minimum follow-up of 10 years
CONCLUSIONS: Concurrent spinal pathology influences THA outcomes at a minimum follow-up of 10 years. Sex, age, and associated lumbar degeneration can affect clinical and radiological changes over time. A decrease in SFP angle values over time was found in patients sustaining late dislocation.PMID:38695378 | DOI:10.1177/11207000241248074 (Source: Hip International)
Source: Hip International - May 2, 2024 Category: Orthopaedics Authors: Eduardo Garc ía-Rey Laura Salda ña Source Type: research
Louis Dominique Le Roy and the first documented and successful crural fracture osteosynthesis, performed in Antwerp in 1796
Conclusion: This is the first successful osteosynthesis and thereby antedates by far the late 19th century cerclage operations of long bones.PMID:38693907 | DOI:10.1080/00015458.2024.2350114 (Source: Acta Chirurgica Belgica)
Source: Acta Chirurgica Belgica - May 2, 2024 Category: Surgery Authors: Robrecht Bob VanHee Source Type: research
A challenging diagnosis of chronic osteomyelitis in a child with congenital insensitivity to pain: a case report
CONCLUSION: This case highlights the challenges faced in diagnosing osteomyelitis among CIP patients and emphasizes the need for other diagnostic criteria apart from pain.PMID:38694364 | PMC:PMC11060246 | DOI:10.1097/MS9.0000000000001971 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Hazem Kamil Riffa Alassri Douaa Albelal Abu Baker Alassri Nafiza Martini Jaber Mahmod Source Type: research
Correction: Relationship between sacral-abdominal wall distance, movement performance, and spinal alignment in osteoporosis: a retrospective study
(Source: BMC Geriatrics)
Source: BMC Geriatrics - May 2, 2024 Category: Geriatrics Authors: Takashi Nagai, Makoto Miyagami, Shota Nakamura, Keizo Sakamoto, Koji Ishikawa, Ichiro Okano, Fumihito Kasai, Yoshifumi Kudo and Nobuyuki Kawate Tags: Correction Source Type: research
Correlation between benign joint hypermobility syndrome and headache in children and adolescents
This study aimed to investigate the prevalence and subtypes of headache in childr... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 2, 2024 Category: Orthopaedics Authors: Mohsen Jari and Sogol Alesaeidi Tags: Research Source Type: research
The effect of a neck-specific exercise program on cervical kinesthesia for patients with chronic whiplash-associated disorders: a case-control study
Cervical kinesthesia is an important part of movement control and of great importance for daily function. Previous research on kinesthesia in whiplash-associated disorders (WAD) has focused on grades I-II. Mor... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 2, 2024 Category: Orthopaedics Authors: Harpa Ragnarsdottir, Gunnel Peterson, Magnus K Gislason, Gudny L Oddsdottir and Anneli Peolsson Tags: Research Source Type: research
Causal roles of educational duration in bone mineral density and risk factors for osteoporosis: a Mendelian randomization study
Educational duration might play a vital role in preventing the occurrence and development of osteoporosis(OP). (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 2, 2024 Category: Orthopaedics Authors: Yujun Qin, Xia Yang and Zong Ning Tags: Research Source Type: research
Effectiveness and safety of polyacrylamide hydrogel injection for knee osteoarthritis: results from a 12-month follow up of an open-label study
There are few effective osteoarthritis (OA) therapies. A novel injectable polyacrylamide hydrogel (iPAAG) previously demonstrated efficacy and safety up to week 26 in an open-label study of knee OA. Here we re... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - May 2, 2024 Category: Orthopaedics Authors: Henning Bliddal, Jannie Beier, Andreas Hartkopp, Philip G. Conaghan and Marius Henriksen Tags: Research article Source Type: research
Three-dimensional printed custom-made modular talus prosthesis in patients with talus malignant tumor resection
Talar malignant tumor is extremely rare. Currently, there are several alternative management options for talus malignant tumor including below-knee amputation, tibio-calcaneal arthrodesis, and homogenous bone ... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - May 2, 2024 Category: Orthopaedics Authors: Xuanhong He, Minxun Lu, Chang Zou, Zhuangzhuang Li, Taojun Gong, Guy Romeo Kenmegne, Yitian Wang, Yi Luo, Yong Zhou, Li Min and Chongqi Tu Tags: Research article Source Type: research
Use of the International IFOMPT Cervical Framework to inform clinical reasoning in postgraduate level physiotherapy students: a qualitative study using think aloud methodology
Vascular pathologies of the head and neck are rare but can present as musculoskeletal problems. The International Federation of Orthopedic Manipulative Physical Therapists (IFOMPT) Cervical Framework (Framewor... (Source: BMC Medical Education)
Source: BMC Medical Education - May 2, 2024 Category: Universities & Medical Training Authors: Katie L. Kowalski, Heather Gillis, Katherine Henning, Paul Parikh, Jackie Sadi and Alison Rushton Tags: Research Source Type: research
The impact of specialized nursing care at fracture sites coordinated with disease progression monitoring in thoracolumbar spine fractures
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - May 2, 2024 Category: Neuroscience Authors: Juan LiuGuiqi ZhangQiuyan ZhaoJuan WangJing ZhangChuanyi Baia Department of Orthopedics, The Second Affiliated Hospital, Xi ’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of Chinab Department of Spinal Surgery, Dalian Municipal Central H Source Type: research
Use of an Artificial Intelligence Device for Evaluating Blood Loss in Complex Major Orthopaedic Surgery Procedures
An artificial intelligence algorithm that analyzes the pulse oximeter waveform in the fingertip can be used to determine the compensatory reserve index (CRI) in trauma patients. This measurement shows the remaining cardiovascular capacity and is known to be more specific and sensitive in detecting blood loss than are routine vital signs. We hypothesized that the CRI measurement could predict loss of reserve cardiovascular capacity in patients undergoing major orthopaedic surgery, and therefore could help in their management. (Source: The Journal of Arthroplasty)
Source: The Journal of Arthroplasty - May 2, 2024 Category: Orthopaedics Authors: Leo A. Whiteside, Marie E. Roy Tags: Proceedings of the Knee Society 2023 Source Type: research
