Opioid use and disposal at 2 weeks post-surgery: Brief communication regarding excess opioids and disposal habits
CONCLUSION: Two-thirds of the patients reported having excess opioids, highlighting the issue of an overabundance of unused prescription opioids in America. Utilization of opioid-free pain management strategies and drug disposal kits should be explored to reduce the number of unused and improperly disposed opioids.PMID:38700391 | DOI:10.5055/jom.0854 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Henry Kuechly Sarah Kurkowski John Bonamer Brian Newyear Brian Johnson Brian Grawe Source Type: research
An in silico approach to elucidate the pathways leading to primary osteoporosis: age-related vs. postmenopausal
Biomech Model Mechanobiol. 2024 May 3. doi: 10.1007/s10237-024-01846-2. Online ahead of print.ABSTRACTNumerical models of bone remodelling have traditionally been used to perform in silico tests of bone loss in postmenopausal women and also to simulate the response to different drug treatments. These models simulate the menopausal oestrogen decline by altering certain signalling pathways. However, they do not consider the simultaneous effect that ageing can have on cell function and bone remodelling, and thus on bone loss. Considering ageing and oestrogen decline together is important for designing osteoporosis treatments ...
Source: Cell Research - May 3, 2024 Category: Cytology Authors: Roc ío Ruiz-Lozano Jos é Luis Calvo-Gallego Peter Pivonka Michelle M McDonald Javier Mart ínez-Reina Source Type: research
Fracture haematoma proteomics
CONCLUSION: The early fxH proteome of the ETC group was characterized by the expression of immunomodulatory, mainly pro-inflammatory, proteins, whereas the early fxH proteome of the DCO group was more regenerative and osteogenic in nature. These findings match clinical observations, in which enhanced surgical trauma after multiple trauma causes dysbalanced inflammation, potentially leading to reduced tissue regeneration, and gained insights into regulatory mechanisms of fracture healing after severe trauma.PMID:38699779 | DOI:10.1302/2046-3758.135.BJR-2023-0323.R1 (Source: Cell Research)
Source: Cell Research - May 3, 2024 Category: Cytology Authors: Rald V M Groven Christel Kuik Johannes Greven Ümit Mert Freek G Bouwman Martijn Poeze Taco J Blokhuis Markus Huber-Lang Frank Hildebrand Berta Cillero-Pastor Martijn van Griensven Source Type: research
The Jerusalem tribune collapse incident: Challenges in the management of a pediatric mass casualty incident
CONCLUSION: Pediatric MCI management presents specific challenges. The lack of consistency in triage, registry, and management highlights the need for robust pediatric MCI training programs.PMID:38698513 | DOI:10.5055/ajdm.0479 (Source: American Journal of Disaster Medicine)
Source: American Journal of Disaster Medicine - May 3, 2024 Category: International Medicine & Public Health Authors: Naama Pines Saar Hashavya Miklosh Bala Kedar Asaf Lea Ohana-Sarna-Cahan Giora Weiser Bat El Shalem David Rekthman Shaden Salameh Source Type: research
Development and validation of a machine learning model to improve precision prediction for irrational prescriptions in orthopedic perioperative patients
CONCLUSION: The RF model showcased significantly high level of proficiency in predicting irrational prescriptions among orthopedic perioperative patients, outperforming other models by a considerable margin. It effectively enhanced the efficiency of pharmacist interventions, displaying outstanding performance in assisting pharmacists to intervene with irrational prescriptions.PMID:38698685 | DOI:10.1080/14740338.2024.2348569 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - May 3, 2024 Category: Drugs & Pharmacology Authors: Weipeng Li Nan Shang Zhiqi Zhang Yun Li Xianlin Li Xiaojun Zheng Source Type: research
Impact of surgical risk factors for non-union on lumbar spinal fusion outcomes using cellular bone allograft at 24-months follow-up
The current report investigates fusion rates and patient-reported outcomes following lumbar spinal surgery using cellular bone allograft (CBA) in patients with risk factors for non-union. (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 3, 2024 Category: Orthopaedics Authors: Anthony Russo, Daniel K Park, Todd Lansford, Pierce Nunley, Timothy A Peppers, Joshua J Wind, Hamid Hassanzadeh, Joseph Sembrano, Jung Yoo and Jonathan Sales Tags: Research Source Type: research
Safety and feasibility of in-hospital autonomous transportation using a driverless mobility for patients with musculoskeletal disorders: preliminary clinical study to achieve mobility as a service in medical care
Recent advancements in and the proliferation of autonomous mobility technology, such as intelligent wheelchairs, have made it possible to provide mobility services for patients with reduced mobility due to mus... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 3, 2024 Category: Orthopaedics Authors: Hiroshi Takahashi, Kenji Suzuki, Tomofumi Nishino, Yosuke Shibao, Hiroshi Noguchi, Akihiro Kanamori, Tomokazu Yoshioka, Naoya Kikuchi, Daisuke Nozawa, Hajime Mishima, Masao Koda and Masashi Yamazaki Tags: Research Source Type: research
Clinical effect of digitalized designed and 3D-printed repositioning splints in the treatment of anterior displacement of temporomandibular joint disc
To compare the treatment effectiveness of digitized and 3D-printed repositioning splints with that of conventional repositioning splints in the treatment of anterior displacement of the temporomandibular joint... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 3, 2024 Category: Orthopaedics Authors: Xiao Jin and Wang Chi Tags: Research Source Type: research
Association of osteoporotic fractures of femoral neck and femoral neck geometric parameters in native Chinese women
Although it is generally believed that the femoral neck fracture is related to the femoral neck geometric parameters (FNGPs), the association between the risk of osteoporotic fracture of the femoral neck and F... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 3, 2024 Category: Orthopaedics Authors: Lin Li, Yi Shen, Li-Hua Tan, Hong Zhang, Ru-Chun Dai, Ling-Qing Yuan, Zhi-Feng Sheng and Xi-Yu Wu Tags: Research Source Type: research
Biomechanical analysis of plate versus K-wire fixation for metacarpal shaft fractures with wedge-shaped bone defects
Metacarpal shaft fracture is a common type of hand fracture. Numerous studies have explored fixing transverse fractures in the midshaft of the metacarpal bone. However, this section of the metacarpal bone is o... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 3, 2024 Category: Orthopaedics Authors: Yung-Cheng Chiu, Tsung-Yu Ho, Cheng-En Hsu, Chen-Wei Yeh, Yen-Nien Ting, Ming-Tzu Tsai and Jui-Ting Hsu Tags: Research Source Type: research
Factors influencing the posterior cruciate ligament buckling phenomenon —a multiple linear regression analysis of bony and soft tissue structures of the knee joint
To determine whether posterior cruciate ligament (PCL) buckling (angular change) is associated with anterior cruciate ligament (ACL) status (intact or ruptured), meniscal bone angle (MBA), anterior tibial tran... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - May 3, 2024 Category: Orthopaedics Authors: Jiaying Zhang, Tianwen Huang, Zhenyu Jia, Yangyang Yang, Tsung-Yuan Tsai and Pingyue Li Tags: Research article Source Type: research
Randomised controlled trial of tourniquet associated pain generated in lower limb after exsanguination by Esmarch bandage versus limb elevation
This study was designed to compare what effect pre-tourniquet Esmarch bandage exsanguination has on pain... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - May 3, 2024 Category: Orthopaedics Authors: Alexander Mitrichev, John Maunder, Aiden Jabur, Prince Singh, Deborah Lees, Levi Morse and Benjamin Parkinson Tags: Research article Source Type: research
Correction: Impact of preoperative anemia on patients undergoing total joint replacement of lower extremity: a systematic review and meta-analysis
(Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - May 3, 2024 Category: Orthopaedics Authors: Fu ‑Qiang Zhang, Yong‑Ze Yang, Peng‑Fei Li, Guo‑Rong Ma, An‑Ren Zhang, Hui Zhang and Hong‑Zhang Guo Tags: Correction Source Type: research
Clinical Outcomes in Prospective versus Retrospective Studies on Arthroscopic Bankart Repair: A Systematic Review
The majority of the current literature on arthroscopic Bankart repair is retrospective and discrepancies exist regarding clinical outcomes including recurrent instability and return to play amongst studies of different levels of evidence. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - May 3, 2024 Category: Orthopaedics Authors: Kaitlyn A. Rodriguez, Eoghan T. Hurley, Mark P. Karavan, Prince Boadi, Ignacio Pasqualini, Jay M. Levin, Brian C. Lau, Christopher S. Klifto, Jonathan F. Dickens Tags: Review Article Source Type: research
Outcomes of total elbow arthroplasty in the treatment of distal humeral fractures in the elderly: A retrospective cohort comparison between primary arthroplasty and arthroplasty secondary to failed internal fixation.
The primary objective of this study was to compare the clinical outcomes of total elbow arthroplasty as the index procedure in the treatment of traumatic distal humerus fractures, with secondary total elbow arthroplasty following failed internal fixation. The secondary objectives were to compare the complication rates and the radiographic results in the two groups. Our hypothesis was that the clinical results of total elbow arthroplasty performed secondarily to failed internal fixation were comparable to primary total elbow arthroplasty in the treatment of distal humerus fractures in the elderly population. (Source: Journa...
Source: Journal of Shoulder and Elbow Surgery - May 3, 2024 Category: Orthopaedics Authors: Stefano Palladino, Florent Baldairon, Julien Godet, Philippe Clavert Tags: Original Article Source Type: research
