Trends in NIH-Supported Basic, Translational, and Clinical Research: FYs 2009-2022
I often hear concerns raised that NIH does not fund enough basic research, or enough applied research for that matter. Basically, the concerns center around what is the correct balance. It is an important point to consider, as a better understanding of these wider research areas can shed light on NIH’s approach to higher-level priority setting and funding decisions. To get at this question, we leveraged the Research, Condition, and Disease Classification (RCDC) system and looked at trends in NIH funding of these areas between fiscal years (FYs) 2009 and 2022. For the purpose of this analysis, we used projects reported...
Source: NIH Extramural Nexus - October 31, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike basic research clinical research Funding data RCDC Source Type: funding

More Early Stage Investigators Supported in FY 2022
Discussion and Funding Rates for PIs on Type 1 R01-Equivalent Applications and Awards in FY 2022 by Career Stage Career StageApplicantsDiscussedAwardeesDiscussion Rate (%)*Funding Rate (%)Early Stage54353466160963.829.6New, Not Early72413750125751.817.4At Risk77364570208759.127.0Established110457847359871.032.6 * The Discussion Rate is a person-based metric that is the percent of applicants (actually people designated as PI’s on an application) who had at least one application make it to the discussion stage of peer review. The next set of tables present aggregate data for sex/gender (Table 3), race (Table 4), e...
Source: NIH Extramural Nexus - June 5, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike ESI Funding data NGRI Source Type: funding

NIAMS Resource-based Centers for Bone, Muscle and Orthopaedic Research (P30 - Clinical Trial Not Allowed)
Funding Opportunity RFA-AR-24-002 from the NIH Guide for Grants and Contracts. NIAMS Resource-based Centers for Bone, Muscle and Orthopaedic Research (P30 - Clinical Trial Not Allowed) (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 27, 2022 Category: Research Source Type: funding

Data on Researchers ’ Self-Reported Disability Status
Ensuring a strong and diverse workforce is a top priority for NIH. To this end, we regularly assess the sex/gender, race, and ethnicity of NIH-supported researchers to better understand the composition of our workforce and participation in our programs. Investigators may self-report their disability status along with these other demographic characteristics on their eRA personal profile. This allows us to learn more about researchers with disabilities in the NIH-supported scientific workforce. Not only is this of interest to NIH, but many in the community have also asked us about this as well. This post presents some of the...
Source: NIH Extramural Nexus - December 13, 2022 Category: Research Authors: Mike Lauer Tags: blog Open Mike Funding data scientific workforce diversity Source Type: funding

FY 2021 Data on Age at Enrollment in Clinical Research Now Available by RCDC Category
We are pleased to announce that for the first time, data are now available on the age of participants in NIH-supported clinical research. The newly available information on age adds to already reported data on participant sex or gender, race, and ethnicity. The NIH Inclusion Across the Lifespan (IAL) policy, implemented in response to the 21st Century Cures Act, requires individuals of all ages (including children and older adults) be included in our supported clinical research absent compelling scientific or ethical reasons. Recipients whose projects fall under the policy have been submitting anonymized individual-level d...
Source: NIH Extramural Nexus - April 11, 2022 Category: Research Authors: Mike Lauer Tags: blog Open Mike Inclusion inclusion across the lifespan RCDC Source Type: funding

Notice of Annual Meeting Addition and Budget Language Change in RFA-AG-22-018 "Leveraging Existing Large Databases and Cohorts to Better Understand the Risks and Benefits of Long-Term Osteoporosis Therapy and Drug Holiday (R01 Clinical Trial Not Allowed)"
Notice NOT-AG-21-032 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 5, 2021 Category: Research Source Type: funding

Data on Implementing NIH ’s Next Generation Researchers Initiative
Discussion Rate” is, like the Funding Rate a person-based metric, and is calculated as the percent of applicants (actually people designated as PI’s on an application) who had at least one application make it to the discussion stage of peer review. As Table 2 indicates, discussion and funding rates in FY 2020 are higher for women in the At Risk and New Not Early groups, but not for the Early Stage and Established groups. Women comprise a greater proportion of Early-Stage Investigator applicants (46%) than any of the other groups including New Investigators, At Risk Investigators and Established Investigators (e.g., wom...
Source: NIH Extramural Nexus - July 12, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike at risk investigators Early Stage Investigators ESI funding Funding data NGRI scientific workforce diversity Source Type: funding

Notice of Change to Award Information for RFA-AG-22-018 Leveraging Existing Large Databases and Cohorts to Better Understand the Risks and Benefits of Long-Term Osteoporosis Therapy and Drug Holiday (R01 Clinical Trial Not Allowed)
Notice NOT-AG-21-030 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 28, 2021 Category: Research Source Type: funding

Leveraging Existing Large Databases and Cohorts to Better Understand the Risks and Benefits of Long-Term Osteoporosis Therapy and Drug Holiday (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-22-018 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits secondary analyses of existing datasets to provide evidence about appropriate strategies for long-term osteoporosis therapies, including drug holidays, and to better understand their risks and benefits. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 17, 2021 Category: Research Source Type: funding

NIAMS Resource-based Centers for Bone, Muscle and Orthopaedic Research (BMOR) (P30 - Clinical Trials Not Allowed)
Funding Opportunity RFA-AR-21-004 from the NIH Guide for Grants and Contracts. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) requests applications for the NIAMS Resource-based Centers Program (P30) for rheumatic diseases research areas within its mission. The Resource-based Centers will provide critical research infrastructure, shared facilities, services, and/or resources to groups of investigators conducting research on rheumatic diseases, enabling them to conduct their independently-funded individual and/or collaborative research projects more efficiently and/or more effectively, w...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 10, 2020 Category: Research Source Type: funding

NCMRR Early Career Research Award (R03 Clinical Trial Optional)
Funding Opportunity PAR-20-042 from the NIH Guide for Grants and Contracts. The National Center for Medical Rehabilitation Research (NCMRR) Early Career Research (ECR) Award (R03) is intended to support both basic and clinical research from rehabilitation scientists who are establishing independent research careers. The research must be focused on one or more of the areas within the biomedical and behavioral mission of NCMRR: pathophysiology and management of chronically injured nervous and musculoskeletal systems (including stroke, traumatic brain injury, spinal cord injury, and orthopedic conditions); repair and recov...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 24, 2019 Category: Research Source Type: funding

NIH Inclusion Data by Research and Disease Category Now Available
This reporting step continues our move towards enhancing transparency and accountability of the research we support. As part of implementing the 21st Century Cures Act and responding to recommendations from the Government Accountability Office, public reporting by NIH Research, Condition, and Disease Classification (RCDC) category helps ensure that women and minorities are appropriately included in biomedical research across a diverse array of diseases and conditions. At a recent meeting of the NIH Advisory Committee on Research on Women’s Health (go to 02:45), where this announcement was made, we also reported that ...
Source: NIH Extramural Nexus - May 6, 2019 Category: Research Authors: Janine Clayton, Dawn Corbett, Marie Bernard, and Mike Lauer Tags: blog Open Mike Inclusion RCDC Source Type: funding

HEAL Initiative: Preventing Opioid Use Disorder in Older Adolescents and Young Adults (ages 1630) (UG3/UH3 Clinical Trial Required)
Funding Opportunity RFA-DA-19-035 from the NIH Guide for Grants and Contracts. This FOA is intended to solicit two-phase research applications to develop, adapt and test interventions and strategies to prevent initiation of opioid misuse and development of OUD in at-risk older adolescents and young adults (ages 16-30). The goal is to stimulate research studies conducted in populations and geographic areas most affected by the opioid crisis or with indicators of an emerging crisis. Of priority are studies that target older adolescents and young adults in health care settings (including primary care, surgical, orthopedic ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 10, 2018 Category: Research Source Type: funding

Understanding Skeletal Effects of Type 1 Diabetes (R01 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites applications for studies to understand the effects of type 1 diabetes (T1D) on bone mass and quality and/or fracture risk. Researchers may propose investigations in newly recruited subjects or using subjects and/or samples from ongoing clinical studies of individuals with for T1D.Saul Malozowski, M.D., Ph.D., M.B.A. | RFA-DK-18-002 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - May 9, 2018 Category: Endocrinology Source Type: funding

Understanding Skeletal Effects of Type 1 Diabetes (R01 Clinical Trial Optional)
Funding Opportunity RFA-DK-18-002 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for studies to understand the effects of type 1 diabetes (T1D) on bone mass and quality and/or fracture risk. Researchers may propose investigations in newly recruited subjects or using subjects and/or samples from ongoing clinical studies of individuals with for T1D. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 8, 2018 Category: Research Source Type: funding