Effect of experimentally induced muscle pain on neuromuscular control of force production
CONCLUSION: Force production decreases and increases during voluntary and involuntary contractions, respectively, suggesting that acute pain impairs force production via central mechanisms.PMID:38636393 | DOI:10.1016/j.humov.2024.103219 (Source: Human Movement Science)
Source: Human Movement Science - April 18, 2024 Category: Neurology Authors: Manoela Vieira Sousa M árcio Goethel Klaus M Becker Fernando Diefenthaeler Ricardo J Fernandes Isabella de Santana Toro Batista Jo ão Paulo Vilas-Boas Ulysses Ervilha Source Type: research
40 years neonatology : An academic life
CONCLUSION: As we look ahead it is imperative to build upon the progress made, harnessing the power of science and technology to further improve the survival and quality of life for preterm infants in Austria and worldwide. At the same time, neonatology must continue to prioritize ethical reflection and education, fostering a culture of integrity, interdisciplinary collaboration, and the development of guidelines and protocols that uphold ethical standards while addressing the evolving needs and complexities of neonatal medicine.PMID:38634910 | DOI:10.1007/s00508-024-02360-2 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 18, 2024 Category: General Medicine Authors: Arnold Pollak Source Type: research
Localization of sensory nerve terminals containing calcitonin gene-related peptide (CGRP) on striated muscle fibers in the rat esophagus: Evidence for triple innervation via motor endplates
CONCLUSIONS: This study suggests that the CGRP-varicose nerve endings containing SP and TRPV1 in motor endplates are sensory, and a few esophageal striated muscle fibers are triply innervated. The nerve endings may detect acetylcholine-derived acetic acid from the vagal motor nerve endings and NO from esophageal intrinsic nerve terminals in the motor endplates to regulate esophageal motility.PMID:38636284 | DOI:10.1016/j.autneu.2024.103177 (Source: Autonomic Neuroscience)
Source: Autonomic Neuroscience - April 18, 2024 Category: Neuroscience Authors: Hirofumi Kuramoto Mana Yabe Ryo Morishita Ryoichi Yoshimura Hiroshi Sakamoto Source Type: research
Comparative Neuroprotective Effects of < em > Moringa oleifera < /em > Seed Oil and Aqueous Extract on Cognitive Functions on a High-Fat, High-Fructose Diet Mice: Focus on Senescence Markers
This study aimed to investigate the neuroprotective effects of MO leaves aqueous extract (MOE) and moringa seed oil (MOO) against brain impairment in mice with HFFD. Twenty-eight male mice were randomly divided into four groups: normal diet, HFFD, HFFD + MOE 500 mg/kgBW, and HFFD + MOO 2 mL/kgBW. Cognitive function was assessed using the Y-maze and novel object recognition (NOR) tests. The p16, p21, and BDNF expressions were analyzed using the RT-PCR method. Senescence-associated beta-galactosidase (SA-β-gal) staining in the brain was also performed. The results showed that administration of MOE or MOO could increase the ...
Source: The Scientific World Journal - April 18, 2024 Category: Science Authors: Wawaimuli Arozal Muhamad Sadam Safutra Agian Jeffilano Barinda Harri Hardi Nounik Cheri Dwita Hee J Lee Source Type: research
DMT1 ubiquitination by Nedd4 protects against ferroptosis after intracerebral hemorrhage
CONCLUSION: The results demonstrated that ferroptosis occurs via the Nedd4/DMT1 pathway during ICH, suggesting it potential as a valuable target to inhibit ferroptosis for the treatment of ICH.PMID:38634270 | PMC:PMC11024684 | DOI:10.1111/cns.14685 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 18, 2024 Category: Neuroscience Authors: Bingchen Lv Ping Fu Miao Wang Likun Cui Lei Bao Xingzhi Wang Lu Yu Chao Zhou Mengxin Zhu Fei Wang Ye Pang Suhua Qi Zuohui Zhang Guiyun Cui Source Type: research
Presence of the neurotoxin β-N-methylamino-L-alanine in irrigation water and accumulation in cereal grains with human exposure risk
Environ Sci Pollut Res Int. 2024 Apr 18. doi: 10.1007/s11356-024-33188-y. Online ahead of print.ABSTRACTThe present study demonstrates the presence of the neurotoxin β-N-methylamino-L-alanine and its cyanobacterial producers in irrigation water and grains of some cereal plants from farmlands irrigated with Nile River water in Egypt. BMAA detected by LC-MS/MS in phytoplankton samples was found at higher concentrations of free form (0.84-11.4 μg L-1) than of protein-bound form (0.16-1.6 μg L-1), in association with the dominance of cyanobacteria in irrigation water canals. Dominant cyanobacterial species isolated from the...
Source: Environmental Science and Pollution Research International - April 18, 2024 Category: Environmental Health Authors: Zakaria A Mohamed Rehab O Elnour Saad Alamri Mohamed Hashem Alexandre Campos Vitor Vasconcelos Hanan Badawye Source Type: research
A Systematic Guideline by the ASPN Workgroup on the Evidence, Education, and Treatment Algorithm for Painful Diabetic Neuropathy: SWEET
CONCLUSION: The ASPN SWEET Guideline represents the most comprehensive review of the available treatments for PDN and their appropriate and safe utilization.PMID:38633823 | PMC:PMC11022879 | DOI:10.2147/JPR.S451006 (Source: Biomed Res)
Source: Biomed Res - April 18, 2024 Category: Research Authors: Dawood Sayed Timothy Ray Deer Jonathan M Hagedorn Asim Sayed Ryan S D'Souza Christopher M Lam Nasir Khatri Zohra Hussaini Scott G Pritzlaff Newaj Mohammad Abdullah Vinicius Tieppo Francio Steven Michael Falowski Yussr M Ibrahim Mark N Malinowski Ryan R Bu Source Type: research
Genetic and Phenotypic Profiling of Triptan Users in a Swedish Cluster Headache Cohort
AbstractUp to 25% of individuals who live with cluster headache (CH), an extremely painful primary headache disorder, do not adequately respond to the first-line treatment, triptans. Studies have indicated that genetic variants can play a role in treatment response. Likewise, differences in clinical characteristics can give clues to mechanisms underlying triptan non-response. Our aim was to investigate five genetic variants previously implicated in triptan response and their relation to triptan usage in our Swedish CH cohort and to investigate potential distinctions in clinical characteristics. 545 CH patients were screene...
Source: Journal of Molecular Neuroscience - April 18, 2024 Category: Neuroscience Source Type: research
Observation of efficacy of rt-PA thrombolysis combined with Solitaire AB stent mechanical thrombectomy in patients with acute ischemic stroke: a retrospective analysis
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 18, 2024 Category: Neuroscience Authors: Yongchang LiuYan LiShaoquan LiSongwang XieJunyong WangJian WangZhen HongDepartment of Neurovascular Intervention, Cangzhou Central Hospital, Cangzhou, China Source Type: research
Research Hotspots and Frontiers of Alzheimer ’s Disease and Gut Microbiota: A Knowledge Mapping and Text Mining Analysis
This study aimed to conduct a bibliometric and visual analysis of published studies related to gut microbiota and AD. Based on the Web of Science Core Collection SCI-Expanded database, we utilize Excel 2019 and v isualization analysis tools VOSviewer, Co-Occurrence13.2 (COOC13.2), Citespace, HistCite, and Bibliometrix (R-Tool of R-Studio) for analysis. A total of 1093 related kinds of literature were included, and the number of papers presented an overall increasing trend. The country/region with the most p ublications is China, the institution is Zhejiang University, the author is Walter J Lukiw from the USA, and the jo...
Source: Molecular Neurobiology - April 18, 2024 Category: Neurology Source Type: research
Adolescent gender dysphoria management: position paper from the Italian Academy of Pediatrics, the Italian Society of Pediatrics, the Italian Society for Pediatric Endocrinology and Diabetes, the Italian Society of Adolescent Medicine and the Italian Society of Child and Adolescent Neuropsychiatry
ConclusionMaintaining an evidence-based approach is essential to safeguard the well-being of transgender and gender diverse adolescents. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 18, 2024 Category: Pediatrics Source Type: research
AMPK pathway: an emerging target to control diabetes mellitus and its related complications
ConclusionAs AMPK activation leads to overall control of diabetes mellitus, designing and developing of small molecules or peptide that can act as AMPK agonist will be highly beneficial for control or manage diabetes mellitus. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 18, 2024 Category: Endocrinology Source Type: research
Effects on brain structural and functional in deaf children after aerobic exercise training: a pilot cluster randomized controlled study
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 18, 2024 Category: Neuroscience Authors: Hang QuHui TangLiping WangWei WangYi ZhaoAiguo ChenChunhong Hua Department of Radiology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Chinab Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou Source Type: research
Analyzing the application of dezocine combined with psychological care in the postoperative pain management of patients with hemifacial spasm
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 18, 2024 Category: Neuroscience Authors: Ying XiaoJiqiong Hea Department of Neurosurgery, First People ’s Hospital of Zunyi City, Guizhou Province, Chinab Department of Stomatology, First People’s Hospital of Zunyi City, Guizhou Province, China Source Type: research
Extract of Gualou-Xiebai Herb Pair Improves Lipid Metabolism Disorders by Enhancing the Reverse Cholesterol Transport in Atherosclerosis Mice
CONCLUSION: In summary, our results suggested that GXE improved lipid metabolism disorders by enhancing RCT, providing a scientific basis for the clinical use of GXE in AS treatment.PMID:38629368 | DOI:10.2174/0115672026308438240405055719 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - April 17, 2024 Category: Neurology Authors: Yarong Liu Tian Wang Lidan Ding Zhenglong Li Yexiang Zhang Min Dai Hongfei Wu Source Type: research
