DMT1 ubiquitination by Nedd4 protects against ferroptosis after intracerebral hemorrhage

CONCLUSION: The results demonstrated that ferroptosis occurs via the Nedd4/DMT1 pathway during ICH, suggesting it potential as a valuable target to inhibit ferroptosis for the treatment of ICH.PMID:38634270 | PMC:PMC11024684 | DOI:10.1111/cns.14685

Source: CNS Neuroscience and Therapeutics - April 18, 2024 Category: Neuroscience Authors: Bingchen Lv Ping Fu Miao Wang Likun Cui Lei Bao Xingzhi Wang Lu Yu Chao Zhou Mengxin Zhu Fei Wang Ye Pang Suhua Qi Zuohui Zhang Guiyun Cui Source Type: research