Biomarkers related to hypertrophy of the ligamentum flavum: a systematic review of the literature
CONCLUSIONS: Biomarkers such as TGF-β, IL-6, and collagen I and III have been consistently correlated with the development of HLF. However, the pathogenesis of HLF remains unclear due to the heterogeneity of the studies, patient populations, and research at the molecular level. Further studies are necessary to better characterize the pathogenesis of HLF and provide a more comprehensive understanding of how these biomarkers may aid in the diagnosis and treatment of HLF.PMID:38608299 | DOI:10.3171/2024.2.SPINE23991 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - April 12, 2024 Category: Neurosurgery Authors: William Mualem Jiaqi Liu Alan Balu Kelsi Chesney M Nathan Nair Source Type: research

Prenatal Diagnosis of Cerebellar Cortical Dysplasia: Case Report
Cerebellum. 2024 Apr 12. doi: 10.1007/s12311-024-01688-9. Online ahead of print.ABSTRACTThis was a study of 12 cerebellar cortical dysplasias (CCDs) fetuses, these cases were characterized by a disorder of cerebellar fissures. Historically, CCD diagnosis was primarily performed using postnatal imaging. Unique to this study was the case series of CCD for prenatal diagnosis using prenatal ultrasound, as well as we found that AXIN1 and FOXC1 mutations may be related to CCD.PMID:38607531 | DOI:10.1007/s12311-024-01688-9 (Source: Cerebellum)
Source: Cerebellum - April 12, 2024 Category: Neuroscience Authors: Yan Ding Zhixuan Chen Huaxuan Wen Dandan Luo Ying Yuan Shaojun Zhang Xiaohong Zhong Shengli Li Source Type: research

How Network Structure Shapes Languages: Disentangling the Factors Driving Variation in Communicative Agents
Cogn Sci. 2024 Apr;48(4):e13439. doi: 10.1111/cogs.13439.ABSTRACTLanguages show substantial variability between their speakers, but it is currently unclear how the structure of the communicative network contributes to the patterning of this variability. While previous studies have highlighted the role of network structure in language change, the specific aspects of network structure that shape language variability remain largely unknown. To address this gap, we developed a Bayesian agent-based model of language evolution, contrasting between two distinct scenarios: language change and language emergence. By isolating the r...
Source: Cognitive Science - April 12, 2024 Category: Neuroscience Authors: Mathilde Josserand Marc Allassonni ère-Tang Fran çois Pellegrino Dan Dediu Bart de Boer Source Type: research

The Role of Attention in Category Representation
This study addresses this issue by examining how components of selective attention affect category representation. Participants first learned a rule-plus-similarity category structure, and then were presented with category priming followed by categorization and recognition tests. Additionally, to evaluate the involvement of focusing and filtering, we fit models with different attentional mechanisms to the data. In Experiment 1, participants received rule-based category training, with specific emphasis on a single deterministic feature (D feature). Experiment 2 added a recognition test to examine participants' memory for fe...
Source: Cognitive Science - April 12, 2024 Category: Neuroscience Authors: Mengcun Gao Brandon M Turner Vladimir M Sloutsky Source Type: research

Valence-Dependent Implicit Action Generalization Among Group Members
Cogn Sci. 2024 Apr;48(4):e13440. doi: 10.1111/cogs.13440.ABSTRACTPeople implicitly generalize the actions of known individuals in a social group to unknown members. However, actions have social goals and evaluative valences, and the extent to which actions with different valences (helpful and harmful) are implicitly generalized among group members remains unclear. We used computer animations to simulate social group actions, where helping and hindering actions were represented by aiding and obstructing another's climb up a hill. Study 1 found that helpful actions are implicitly expected to be shared among members of the sa...
Source: Cognitive Science - April 12, 2024 Category: Neuroscience Authors: Jiecheng Huangliang Yinfeng Hu Xutao Zheng Zikai Xu Wenying Zhou Jun Yin Source Type: research

Sound symbolism in manual and vocal responses: phoneme-response interactions associated with grasping as well as vertical and size dimensions of keypresses
Cogn Process. 2024 Apr 12. doi: 10.1007/s10339-024-01188-y. Online ahead of print.ABSTRACTIt has been shown that reading the vowel [i] and consonant [t] facilitates precision grip responses, while [ɑ] and [k] are associated with faster power grip responses. A similar effect has been observed when participants perform responses with small or large response keys. The present study investigated whether the vowels and consonants could produce different effects with the grip responses and keypresses when the speech units are read aloud (Experiment 1) or silently (Experiment 2). As a second objective, the study investigated whe...
Source: Cognitive Processing - April 12, 2024 Category: Neuroscience Authors: L Vainio I L Myllyl ä M Vainio Source Type: research

Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis
CONCLUSION: Our findings indicate that NASP may serve as a potential biomarker of GBM radioresistance and has important implications for improving clinical radiotherapy.PMID:38605477 | PMC:PMC11009454 | DOI:10.1111/cns.14709 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 12, 2024 Category: Neuroscience Authors: Yuning Qiu Dongling Pei Minkai Wang Qimeng Wang Wenchao Duan Li Wang Kehan Liu Yu Guo Lin Luo Zhixuan Guo Fangzhan Guan Zilong Wang Aoqi Xing Zhongyi Liu Zeyu Ma Guozhong Jiang Dongming Yan Xianzhi Liu Zhenyu Zhang Weiwei Wang Source Type: research

Biomarkers related to hypertrophy of the ligamentum flavum: a systematic review of the literature
CONCLUSIONS: Biomarkers such as TGF-β, IL-6, and collagen I and III have been consistently correlated with the development of HLF. However, the pathogenesis of HLF remains unclear due to the heterogeneity of the studies, patient populations, and research at the molecular level. Further studies are necessary to better characterize the pathogenesis of HLF and provide a more comprehensive understanding of how these biomarkers may aid in the diagnosis and treatment of HLF.PMID:38608299 | DOI:10.3171/2024.2.SPINE23991 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - April 12, 2024 Category: Neurosurgery Authors: William Mualem Jiaqi Liu Alan Balu Kelsi Chesney M Nathan Nair Source Type: research

Biomarkers related to hypertrophy of the ligamentum flavum: a systematic review of the literature
CONCLUSIONS: Biomarkers such as TGF-β, IL-6, and collagen I and III have been consistently correlated with the development of HLF. However, the pathogenesis of HLF remains unclear due to the heterogeneity of the studies, patient populations, and research at the molecular level. Further studies are necessary to better characterize the pathogenesis of HLF and provide a more comprehensive understanding of how these biomarkers may aid in the diagnosis and treatment of HLF.PMID:38608299 | DOI:10.3171/2024.2.SPINE23991 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - April 12, 2024 Category: Neurosurgery Authors: William Mualem Jiaqi Liu Alan Balu Kelsi Chesney M Nathan Nair Source Type: research

Prenatal Diagnosis of Cerebellar Cortical Dysplasia: Case Report
Cerebellum. 2024 Apr 12. doi: 10.1007/s12311-024-01688-9. Online ahead of print.ABSTRACTThis was a study of 12 cerebellar cortical dysplasias (CCDs) fetuses, these cases were characterized by a disorder of cerebellar fissures. Historically, CCD diagnosis was primarily performed using postnatal imaging. Unique to this study was the case series of CCD for prenatal diagnosis using prenatal ultrasound, as well as we found that AXIN1 and FOXC1 mutations may be related to CCD.PMID:38607531 | DOI:10.1007/s12311-024-01688-9 (Source: Cerebellum)
Source: Cerebellum - April 12, 2024 Category: Neuroscience Authors: Yan Ding Zhixuan Chen Huaxuan Wen Dandan Luo Ying Yuan Shaojun Zhang Xiaohong Zhong Shengli Li Source Type: research

Sound symbolism in manual and vocal responses: phoneme-response interactions associated with grasping as well as vertical and size dimensions of keypresses
Cogn Process. 2024 Apr 12. doi: 10.1007/s10339-024-01188-y. Online ahead of print.ABSTRACTIt has been shown that reading the vowel [i] and consonant [t] facilitates precision grip responses, while [ɑ] and [k] are associated with faster power grip responses. A similar effect has been observed when participants perform responses with small or large response keys. The present study investigated whether the vowels and consonants could produce different effects with the grip responses and keypresses when the speech units are read aloud (Experiment 1) or silently (Experiment 2). As a second objective, the study investigated whe...
Source: Cognitive Processing - April 12, 2024 Category: Neuroscience Authors: L Vainio I L Myllyl ä M Vainio Source Type: research

Valence-Dependent Implicit Action Generalization Among Group Members
Cogn Sci. 2024 Apr;48(4):e13440. doi: 10.1111/cogs.13440.ABSTRACTPeople implicitly generalize the actions of known individuals in a social group to unknown members. However, actions have social goals and evaluative valences, and the extent to which actions with different valences (helpful and harmful) are implicitly generalized among group members remains unclear. We used computer animations to simulate social group actions, where helping and hindering actions were represented by aiding and obstructing another's climb up a hill. Study 1 found that helpful actions are implicitly expected to be shared among members of the sa...
Source: Cognitive Science - April 12, 2024 Category: Neuroscience Authors: Jiecheng Huangliang Yinfeng Hu Xutao Zheng Zikai Xu Wenying Zhou Jun Yin Source Type: research

The Role of Attention in Category Representation
This study addresses this issue by examining how components of selective attention affect category representation. Participants first learned a rule-plus-similarity category structure, and then were presented with category priming followed by categorization and recognition tests. Additionally, to evaluate the involvement of focusing and filtering, we fit models with different attentional mechanisms to the data. In Experiment 1, participants received rule-based category training, with specific emphasis on a single deterministic feature (D feature). Experiment 2 added a recognition test to examine participants' memory for fe...
Source: Cognitive Science - April 12, 2024 Category: Neuroscience Authors: Mengcun Gao Brandon M Turner Vladimir M Sloutsky Source Type: research

How Network Structure Shapes Languages: Disentangling the Factors Driving Variation in Communicative Agents
Cogn Sci. 2024 Apr;48(4):e13439. doi: 10.1111/cogs.13439.ABSTRACTLanguages show substantial variability between their speakers, but it is currently unclear how the structure of the communicative network contributes to the patterning of this variability. While previous studies have highlighted the role of network structure in language change, the specific aspects of network structure that shape language variability remain largely unknown. To address this gap, we developed a Bayesian agent-based model of language evolution, contrasting between two distinct scenarios: language change and language emergence. By isolating the r...
Source: Cognitive Science - April 12, 2024 Category: Neuroscience Authors: Mathilde Josserand Marc Allassonni ère-Tang Fran çois Pellegrino Dan Dediu Bart de Boer Source Type: research

Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis
CONCLUSION: Our findings indicate that NASP may serve as a potential biomarker of GBM radioresistance and has important implications for improving clinical radiotherapy.PMID:38605477 | DOI:10.1111/cns.14709 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 12, 2024 Category: Neuroscience Authors: Yuning Qiu Dongling Pei Minkai Wang Qimeng Wang Wenchao Duan Li Wang Kehan Liu Yu Guo Lin Luo Zhixuan Guo Fangzhan Guan Zilong Wang Aoqi Xing Zhongyi Liu Zeyu Ma Guozhong Jiang Dongming Yan Xianzhi Liu Zhenyu Zhang Weiwei Wang Source Type: research