Bionic reconstruction : Restoration of extremity function with osseointegrated and mind-controlled prostheses.
CONCLUSIONS: Bionic reconstruction is a sophisticated method for restoring extremity function and nowadays can be considered a standard of care for all levels of upper extremity amputations. An interdisciplinary approach and structured rehabilitation are necessary to master prosthetic function to ultimately reintegrate patients into daily life. PMID: 31201567 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - June 14, 2019 Category: General Medicine Authors: Aman M, Festin C, Sporer ME, Gstoettner C, Prahm C, Bergmeister KD, Aszmann OC Tags: Wien Klin Wochenschr Source Type: research

Evaluation of pulmonary venous variations in a  large cohort : Multidetector computed tomography study with new variations.
CONCLUSION: The use of MDCT with 3D imaging is a preferable imaging tool for demonstrating pulmonary venous anatomy in detail, which shows significant variability. Considering the high prevalence of variations in the population, performing preprocedural MDCT may facilitate higher success rates in radiofrequency catheter ablation (RFCA) and help to perform safe and accurate surgery especially in video-assisted thoracic surgery (VATS). PMID: 31190096 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - June 12, 2019 Category: General Medicine Authors: Altinkaynak D, Koktener A Tags: Wien Klin Wochenschr Source Type: research

Fine and ultrafine particle exposure during commuting by subway in Vienna.
r D Abstract Mass concentrations of particulate matter (PM10, PM2.5, PM1), lung deposited surface area and particle number concentrations were measured for the first time in all Viennese subway lines inside cabins and in two subway stations, one aboveground and the other underground. The observed data were examined for significant differences between the exposure to fine particulate matter and ultrafine particles. Analysis of the trip averages in the five lines U1, U2, U3, U4 and U6 showed significant differences for PM10, PM2.5 and PM1 (all three mass concentrations: p 
Source: Wiener Klinische Wochenschrift - June 7, 2019 Category: General Medicine Authors: Posselt KP, Neuberger M, Köhler D Tags: Wien Klin Wochenschr Source Type: research

Curriculum heart failure : Task force curriculum heart failure of the working group on heart failure of the Austrian Cardiological Society.
ölzl G Abstract It is well recognized that organized management of heart failure patients, including care by heart failure specialists, improves outcomes of these patients. In response to this, the Heart Failure Association of the European Society of Cardiology proposed a basic framework of a heart failure curriculum, which became a blueprint for training programs across Europe. The present curriculum for heart failure was well coordinated with the version issued by the German Society for Cardiology in order to achieve good comparability. Training in this Austrian curriculum takes two years, during which...
Source: Wiener Klinische Wochenschrift - May 30, 2019 Category: General Medicine Authors: Berger R, Hülsmann M, Mörtl D, Pölzl G Tags: Wien Klin Wochenschr Source Type: research

Childhood tuberculosis in Vienna between 2010 and 2016.
scher T Abstract BACKGROUND: Tuberculosis (TB) has become a rare disease in developed countries. Austria is a low incidence country for TB with an incidence rate of 7.2/100,000 in 2016. The incidence of TB has shown a constant decline in Austria from 2008 (9.8/100,000) to 2015 (6.7/100,000) but recently stagnated in 2016 (7.2/100,000). In recent years migration to Austria from countries with high TB incidence rates has increased. Therefore, this study aimed to describe the recent epidemiology of childhood TB in Vienna. METHODS: Data of pediatric patients with active TB infections, who were hosp...
Source: Wiener Klinische Wochenschrift - May 23, 2019 Category: General Medicine Authors: Unterweger M, Götzinger F, Bogyi M, Zacharasiewicz A, Mädel C, Tiringer K, Reinweber M, Frischer T Tags: Wien Klin Wochenschr Source Type: research

Association between fulfilling the recommendations for health-enhancing physical activity with (instrumental) activities of daily living in older Austrians.
CONCLUSION: The number of participants who did not fulfil the minimal requirements for aerobic or strengthening PA was very high, and these participants showed significantly more problems in ADLs and IADLs. Therefore, all future efforts should focus on increasing participation and adherence in exercise programs for older people with the intention to improve their performance status and functions in daily life. PMID: 31119390 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 22, 2019 Category: General Medicine Authors: Crevenna R, Dorner TE Tags: Wien Klin Wochenschr Source Type: research

Implementation of patient-centered physical training for older people accessing routine health care.
PMID: 31115650 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 21, 2019 Category: General Medicine Authors: Dorner TE Tags: Wien Klin Wochenschr Source Type: research

Pilot study of an integrated care model using the geriatric assessment tool.
CONCLUSION: This intervention is one of the first in the health system in Kosovo to implement integrated care in a very vulnerable population. Physical training will be an important tool to tackle many problems detected through the geriatric assessment and which are also associated with type 2 diabetes mellitus. PMID: 31115651 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 21, 2019 Category: General Medicine Authors: Bytyci A, Ymerhalili G, Dorner TE, Stein KV, Maxhera O Tags: Wien Klin Wochenschr Source Type: research

Beatmung bei COPD: von der Pr äklinik bis zur außerklinischen Beatmung. Eine Übersicht des Arbeitskreises für Beatmung und Intensivmedizin der österreichischen Gesellschaft für Pneumologie.
Beatmung bei COPD: von der Präklinik bis zur außerklinischen Beatmung. Eine Übersicht des Arbeitskreises für Beatmung und Intensivmedizin der österreichischen Gesellschaft für Pneumologie. Wien Klin Wochenschr. 2019 May 20;: Authors: Kink E, Erler L, Fritz W, Funk GC, Gäbler M, Krenn F, Kühteubl G, Schindler O, W.e T Abstract This paper was created by the Austrian Society of Pneumology (Working group Ventilation and Intensive Care) to summarize the specific characteristics of mechanical ventilation in patients presenting with chronic obstructive pulmonary disea...
Source: Wiener Klinische Wochenschrift - May 20, 2019 Category: General Medicine Authors: Kink E, Erler L, Fritz W, Funk GC, Gäbler M, Krenn F, Kühteubl G, Schindler O, Wanke T Tags: Wien Klin Wochenschr Source Type: research

How many women take oral supplementation in pregnancy in Austria? : Who recommended it? A cross-sectional study.
CONCLUSION: Overall, 67% of pregnant women took iron-containing compounds, irrespective of whether they were deficient in iron. Physicians were generally responsible for advising them to take them. No standardized procedure is available on which to base the decision whether to take iron during pregnancy, even in guidelines. As most guidelines only recommend taking iron supplements in cases of anemia, the high percentage of women taking them in Austria is incomprehensible. PMID: 31098837 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 16, 2019 Category: General Medicine Authors: Spary-Kainz U, Semlitsch T, Rundel S, Avian A, Herzog S, Jakse H, Siebenhofer A Tags: Wien Klin Wochenschr Source Type: research

Role of physical medicine for cancer rehabilitation and return to work under the premise of the "Wiedereingliederungsteilzeitgesetz".
CONCLUSION: Early information about cancer rehabilitation and the WIETZ seems to be necessary to facilitate return to work of cancer survivors. Furthermore, exercise interventions seem to be the most important measures from the field of physical medicine and rehabilitation. PMID: 31087151 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 13, 2019 Category: General Medicine Authors: Cenik F, Mähr B, Palma S, Keilani M, Nowotny T, Crevenna R Tags: Wien Klin Wochenschr Source Type: research

Alpha-gal allergy after a  tick bite in Austria.
This article reports on a 51-year-old Austrian male who acquired a tick bite in Austria in spring 2017, which, within 48 h, resulted in prolonged inflammation of the skin area around the bite. The patient experienced an allergic reaction 3 months later approximately 8 h after eating a medium rare steak for dinner. The symptoms included an itchy rash on both sides of the torso and on both arms which persisted for several hours. In spring 2018, the patient suffered another tick bite. The patient's skin reaction was similar to that of the previous year. In the following months, the patient experienced five episo...
Source: Wiener Klinische Wochenschrift - May 13, 2019 Category: General Medicine Authors: Pisazka V, Duscher G, Hodžić A, Reider N, Allerberger F Tags: Wien Klin Wochenschr Source Type: research

Parental obligation to vaccinate children under Austrian civil law?
PMID: 31087153 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 13, 2019 Category: General Medicine Authors: Groman H Tags: Wien Klin Wochenschr Source Type: research

Evaluation of the clinical relevance of vancomycin for the treatment of Lyme disease.
Abstract Vancomycin is active in vitro and in vivo in mouse systems against Lyme disease borrelia; however, there are no published data on the efficacy of vancomycin in patients with Lyme disease and no convincing theoretical advantages of vancomycin over the currently used and highly effective orally administered antimicrobial agents, including doxycycline, amoxicillin and cefuroxime axetil. In addition, vancomycin may cause a wide variety of potentially serious adverse effects and requires the placement of an intravenous catheter. It is concluded that vancomycin is a much less attractive option for the...
Source: Wiener Klinische Wochenschrift - May 10, 2019 Category: General Medicine Authors: Wormser GP, Barbour AG Tags: Wien Klin Wochenschr Source Type: research

Association between physical activity and the utilization of general practitioners in different age groups.
CONCLUSION: The association of PA and GP consultation is dependent on age and type of PA, and partly mediated by sociodemographic and health-related factors. PMID: 31076889 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 10, 2019 Category: General Medicine Authors: Dorner TE, Wilfinger J, Hoffman K, Lackinger C Tags: Wien Klin Wochenschr Source Type: research

Real-world extravascular lung water index measurements in critically ill patients : Pulse index continuous cardiac output measurements: time course analysis and association with clinical characteristics.
This study describes real world extravascular lung water index (EVLWI) measurements at three time points and relates them to other hemodynamic parameters and mortality in critically ill patients admitted to a medical intensive care unit (ICU). METHODS: A total of 198 patients admitted to a tertiary medical university hospital between February 2004 and December 2010 were included in this retrospective analysis. Patients were admitted for various diseases such as sepsis (n = 22), myocardial infarction (n = 53), pulmonary embolism (n = 3), cardiopulmonary resuscitation (n = 1...
Source: Wiener Klinische Wochenschrift - May 8, 2019 Category: General Medicine Authors: Werner M, Wernly B, Lichtenauer M, Franz M, Kabisch B, Muessig JM, Masyuk M, Schulze PC, Hoppe UC, Kelm M, Lauten A, Jung C Tags: Wien Klin Wochenschr Source Type: research

Tick saliva and its role in pathogen transmission.
Abstract Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid engorgement. The composition of tick saliva changes as feeding progresses and the tick counters the dynamic host response. Ixodid ticks such as Ixodes ricinus, the most important tick species in Europe, transmit numerous pathogens that cause debilitating diseases, e.g. Lyme borreliosis and tick-borne encephalitis. Tick-borne pathogens are transmitted in tick saliva during blood feeding; however, saliva is not simply a medium enabling pathogen transfer. Instead, tick-borne pathogens exploit saliva-induced modulation ...
Source: Wiener Klinische Wochenschrift - May 6, 2019 Category: General Medicine Authors: Nuttall PA Tags: Wien Klin Wochenschr Source Type: research

Vascular cell adhesion molecule  1 in patients with severe osteoarthritis of the hip : A prospective cross-sectional study.
CONCLUSION: The results of this study show that serum concentrations of VCAM-1 cannot distinguish patients with severe hip OA from age and sex-matched controls. PMID: 31037360 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 29, 2019 Category: General Medicine Authors: Oppl B, Datz C, Huber-Schönauer U, Husar-Memmer E, Brozek W, Zenz P, Gollob E, Wurnig C, Engel A, Klaushofer K, Zwerina J, Bartko J Tags: Wien Klin Wochenschr Source Type: research

Incidence, etiology, predictors and outcomes of suspected drug hypersensitivity reactions in a  tertiary care university hospital's emergency department : A retrospective study.
In this study 74,929 ED records obtained from March 2012 to March 2015 were reviewed to determine the incidence, etiology, predictors and clinical features of drug hypersensitivity. RESULTS: The observed incidence of drug hypersensitivity was 0.87% of all ED admissions. It was significantly higher in female patients aged 18-29 years (2.26%; P 
Source: Wiener Klinische Wochenschrift - April 29, 2019 Category: General Medicine Authors: Bielen C, Bielen L, Likić R Tags: Wien Klin Wochenschr Source Type: research

Influence of electrical stimulation therapy on permanent pacemaker function.
CONCLUSION: The use of EST potentially interferes with PM therapy, especially if the electrodes are positioned bilaterally; however, unilateral EST application appeared to be safe in all tested configurations. PMID: 31025164 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 25, 2019 Category: General Medicine Authors: Egger F, Hofer C, Hammerle FP, Löfler S, Nürnberg M, Fiedler L, Kriz R, Kern H, Huber K Tags: Wien Klin Wochenschr Source Type: research

Acupuncture is effective in improving functional communication in post-stroke aphasia : A  systematic review and meta-analysis of randomized controlled trials.
Acupuncture is effective in improving functional communication in post-stroke aphasia : A systematic review and meta-analysis of randomized controlled trials. Wien Klin Wochenschr. 2019 Apr 18;: Authors: Zhang B, Han Y, Huang X, Liu Z, Li S, Chang J, Gao Y Abstract OBJECTIVE: In this meta-analysis the authors evaluated the effectiveness of acupuncture in improving functional communication and language function in post-stroke aphasia (PSA) patients. METHODS: Data sources: MEDLINE, EMBASE, CENTRAL, AMED, SinoMed, CNKI, VIP, and Wanfang databases, ICTRP, ISRCTN, EUCTR, ClinicalTrials.gov, and S...
Source: Wiener Klinische Wochenschrift - April 18, 2019 Category: General Medicine Authors: Zhang B, Han Y, Huang X, Liu Z, Li S, Chang J, Gao Y Tags: Wien Klin Wochenschr Source Type: research

Migrate your mind: the role of palliative care in transcultural cancer treatment : A  qualitative analysis.
CONCLUSION: This study revealed first insights into possibilities and prospects of transcultural palliative care for migrants and their relatives. The results might have important implications for the end of life care in this growing population. PMID: 30997564 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 17, 2019 Category: General Medicine Authors: Roider-Schur S, Rumpold T, Kirchheiner K, Masel EK, Nemecek R, Amering M, Watzke H, Schrank B Tags: Wien Klin Wochenschr Source Type: research

Zusammenfassung der Überarbeitungen 2019.
Zusammenfassung der Überarbeitungen 2019. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Winhofer-Stöckl Y, Clodi M, Kautzky-Willer A PMID: 30980141 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Winhofer-Stöckl Y, Clodi M, Kautzky-Willer A Tags: Wien Klin Wochenschr Source Type: research

[Individualising antihypertensive therapy in patients with diabetes.  A guideline by the Austrian Diabetes Association (Update 2019)].
[Individualising antihypertensive therapy in patients with diabetes. A guideline by the Austrian Diabetes Association (Update 2019)]. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Schernthaner G, Saely CH, Schernthaner GH, Watschinger B, Drexel H Abstract Hypertension is one of the most important comorbidities of diabetes, contributing significantly to death and leads to macrovascular and microvascular complications. When assessing the medical priorities for patients with diabetes, treating hypertension should be a primary consideration. In the present review practical approaches to...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Schernthaner G, Saely CH, Schernthaner GH, Watschinger B, Drexel H Tags: Wien Klin Wochenschr Source Type: research

[Diabetic neuropathy and diabetic foot syndrome (Update 2019)].
r G Abstract These are the guidelines for diagnosis and treatment of diabetic neuropathy and diabetic foot. Diabetic neuropathy comprises a number of mono- and polyneuropathies, plexopathies, radiculopathies and autonomic neuropathy.The position statement summarizes characteristic clinical symptoms and techniques for diagnostic assessment of diabetic neuropathy, including the complex situation of the diabetic foot syndrome. Recommendations for the therapeutic management of diabetic neuropathy, especially for the control of pain in sensorimotor neuropathy, are provided. The needs to prevent and treat diabetic ...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Lechleitner M, Abrahamian H, Francesconi C, Kofler M, Sturm W, Köhler G Tags: Wien Klin Wochenschr Source Type: research

[Diabetic kidney disease (Update 2019) : Position paper of the Austrian Diabetes Association and the Austrian Society for Nephrology].
AR Abstract Recent epidemiological investigations have shown that approximately 2-3% of all Austrians suffer from diabetes with renal involvement, i. e. 250,000 people in Austria are affected. The risk of occurrence and progression of this disease can be ameliorated by life style interventions as well as optimization of blood pressure, blood glucose levels and special drug classes. The present article represents the joint recommendations of the Austrian Diabetes Association and the Austrian Society for Nephrology for the diagnostics and treatment strategies of diabetic kidney disease. PMID: 30980144 [PubMe...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Sourij H, Edlinger R, Prischl FC, Auinger M, Kaser S, Horn S, Paulweber B, Kautzky-Willer A, Säemann M, Prager R, Clodi M, Schernthaner G, Mayer G, Oberbauer R, Rosenkranz AR Tags: Wien Klin Wochenschr Source Type: research

[Diagnosis and insulin therapy of type  1 diabetes mellitus (Update 2019)].
[Diagnosis and insulin therapy of type 1 diabetes mellitus (Update 2019)]. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Lechleitner M, Kaser S, Hoppichler F, Roden M, Weitgasser R, Ludvik B, Fasching P, Winhofer-Stöckl Y, Kautzky-Willer A, Schernthaner G, Prager R, Wascher TC, Clodi M Abstract This guideline summarizes diagnosis of type 1 diabetes, including accompanying autoimmune disorders, insulin therapy regimens and glycemic target values. PMID: 30980145 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Lechleitner M, Kaser S, Hoppichler F, Roden M, Weitgasser R, Ludvik B, Fasching P, Winhofer-Stöckl Y, Kautzky-Willer A, Schernthaner G, Prager R, Wascher TC, Clodi M Tags: Wien Klin Wochenschr Source Type: research

[Insulin pump therapy in children, adolescents and adults, guidelines (Update 2019)].
asser R Abstract This position statement is based on current evidence available on the safety and benefits of continuous subcutaneous insulin infusion therapy (CSII, pump therapy) in diabetes with an emphasis on the effects of CSII on glycemic control, hypoglycaemia rates, occurrence of ketoacidosis, quality of life and the use of insulin pump therapy in pregnancy. The current article represents the recommendations of the Austrian Diabetes Association for the clinical praxis of insulin pump treatment in children, adolescents and adults. PMID: 30980146 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Schütz-Fuhrmann I, Stadler M, Zlamal-Fortunat S, Rami-Merhar B, Fröhlich-Reiterer E, Hofer SE, Mader J, Resl M, Bischof M, Kautzky-Willer A, Weitgasser R Tags: Wien Klin Wochenschr Source Type: research

[Insulin therapy of type  2 diabetes mellitus (Update 2019)].
[Insulin therapy of type 2 diabetes mellitus (Update 2019)]. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Lechleitner M, Clodi M, Abrahamian H, Brath H, Brix J, Drexel H, Fasching P, Föger B, Francesconi C, Fröhlich-Reiterer E, Harreiter J, Hofer SE, Hoppichler F, Huber J, Kaser S, Kautzky-Willer A, Ludvik B, Luger A, Mader JK, Paulweber B, Pieber T, Prager R, Rami-Merhar B, Resl M, Riedl M, Roden M, Saely CH, Schelkshorn C, Schernthaner G, Sourij H, Stechemesser L, Stingl H, Toplak H, Wascher TC, Weitgasser R, Winhofer-Stöckl Y, Zlamal-Fortunat S Abstract The present article ...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Lechleitner M, Clodi M, Abrahamian H, Brath H, Brix J, Drexel H, Fasching P, Föger B, Francesconi C, Fröhlich-Reiterer E, Harreiter J, Hofer SE, Hoppichler F, Huber J, Kaser S, Kautzky-Willer A, Ludvik B, Luger A, Mader JK, Paulweber B, Pieber T, Prager Tags: Wien Klin Wochenschr Source Type: research

[Antihyperglycemic treatment guidelines for diabetes mellitus type  2 (Update 2019)].
[Antihyperglycemic treatment guidelines for diabetes mellitus type 2 (Update 2019)]. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Clodi M, Abrahamian H, Brath H, Brix J, Drexel H, Fasching P, Föger B, Francesconi C, Fröhlich-Reiterer E, Harreiter J, Hofer SE, Hoppichler F, Huber J, Kaser S, Kautzky-Willer A, Lechleitner M, Ludvik B, Luger A, Mader JK, Paulweber B, Pieber T, Prager R, Rami-Merhar B, Resl M, Riedl M, Roden M, Saely CH, Schelkshorn C, Schernthaner G, Sourij H, Stechemesser L, Stingl H, Toplak H, Wascher TC, Weitgasser R, Winhofer-Stöckl Y, Zlamal-Fortunat S Abstract H...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Clodi M, Abrahamian H, Brath H, Brix J, Drexel H, Fasching P, Föger B, Francesconi C, Fröhlich-Reiterer E, Harreiter J, Hofer SE, Hoppichler F, Huber J, Kaser S, Kautzky-Willer A, Lechleitner M, Ludvik B, Luger A, Mader JK, Paulweber B, Pieber T, Prager Tags: Wien Klin Wochenschr Source Type: research

[Diabetes mellitus in childhood and adolescence (Update 2019)].
SE Abstract In contrast to adults, type 1 diabetes mellitus (T1D) is the most frequent form of diabetes in childhood and adolescence (>95%). After diagnosis the management of children and adolescents with T1D should take place in highly specialized pediatric units experienced in pediatric diabetology and not in private practices. The lifelong substitution of insulin is the cornerstone of treatment whereby modalities need to be individually adapted for patient age and the family routine. Diabetes education is essential in the management of patients with diabetes and their families and needs to be performed...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Rami-Merhar B, Fröhlich-Reiterer E, Hofer SE Tags: Wien Klin Wochenschr Source Type: research

[Gestational diabetes mellitus (Update 2019)].
r R Abstract Gestational diabetes mellitus (GDM) is defined as a glucose tolerance disorder with onset during pregnancy and is associated with increased feto-maternal morbidity as well as long-term complications in mother and child. Women who fulfil the criteria of a manifest diabetes in early pregnancy (fasting plasma glucose>126 mg/dl, spontaneous glucose level>200 mg/dl or HbA1c > 6.5% before 20 weeks of gestation) should be classified as having manifest diabetes in pregnancy and treated as such. Screening for undiagnosed type 2 diabetes at the first prenatal visit (evidence...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Kautzky-Willer A, Harreiter J, Winhofer-Stöckl Y, Bancher-Todesca D, Berger A, Repa A, Lechleitner M, Weitgasser R Tags: Wien Klin Wochenschr Source Type: research

[Diabetes mellitus-Definition, classification, diagnosis, screening and prevention (Update 2019)].
Abstract Diabetes mellitus comprises a group of heterogeneous disorders, which have an increase in blood glucose concentrations in common. The current classification for diabetes mellitus is presented and the main features of type 1 and type 2 diabetes are compared. Furthermore, the criteria for the correct biochemical diagnosis during fasting and oral glucose tolerance tests as well as the use of hemoglobin A1c (HbA1c) are summarized. The increasing prevalence of diabetes requires targeted screening for detecting diabetes and prediabetes in risk groups. This forms the basis for the early initiation...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Harreiter J, Roden M Tags: Wien Klin Wochenschr Source Type: research

[Diabetes mellitus, coronary artery disease und heart disease (Update  2019)].
[Diabetes mellitus, coronary artery disease und heart disease (Update 2019)]. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Clodi M, Saely CH, Hoppichler F, Resl M, Steinwender C, Stingl H, Wascher TC, Winhofer-Stöckl Y, Sourij H Abstract Diabetes mellitus, cardiovascular disease and heart failure are interacting dynamically. Patients being diagnosed with cardiovascular disease should be screened for diabetes mellitus. Enhanced cardiovascular risk stratification based on biomarkers, symptoms and classical risk factors should be performed in patients with pre-existing diabetes mellitus. In pat...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Clodi M, Saely CH, Hoppichler F, Resl M, Steinwender C, Stingl H, Wascher TC, Winhofer-Stöckl Y, Sourij H Tags: Wien Klin Wochenschr Source Type: research

[Sex and gender-specific aspects in prediabetes and diabetes mellitus-clinical recommendations (Update 2019)].
Abstract Metabolic diseases dramatically affect the life of men and women from infancy up to old age in different and manifold ways and are a major challenge for the healthcare system. The treating physicians are confronted with the different needs of women and men in the clinical routine. Gender-specific differences affect screening, diagnostic and treatment strategies as well as the development of complications and mortality rates. Impairments in glucose and lipid metabolism, regulation of energy balance and body fat distribution and therefore the associated cardiovascular diseases, are greatly influenced b...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Kautzky-Willer A, Harreiter J, Abrahamian H, Weitgasser R, Fasching P, Hoppichler F, Lechleitner M Tags: Wien Klin Wochenschr Source Type: research

["Diabesity"-Obesity and type 2 diabetes (Update 2019)].
["Diabesity"-Obesity and type 2 diabetes (Update 2019)]. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Toplak H, Leitner DR, Harreiter J, Hoppichler F, Wascher TC, Schindler K, Ludvik B Abstract For several years obesity and type 2 diabetes have been increasingly summarized under the name "diabesity". This is due to the fact that in most cases obesity precedes diabetes and is the most important risk factor for the worldwide increase of type 2 diabetes. The body mass index (BMI) is a very crude measure of body fatness in individuals. Even normal weight persons can have...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Toplak H, Leitner DR, Harreiter J, Hoppichler F, Wascher TC, Schindler K, Ludvik B Tags: Wien Klin Wochenschr Source Type: research

[Blood glucose self monitoring (Update 2019)].
Abstract Self monitoring of blood glucose contributes to the integrated management of diabetes mellitus. It, thus, should be available for all patients with diabetes mellitus. Self monitoring of blood glucose improves patients safety, quality of life and glucose control. The current article represents the recommendations of the Austrian Diabetes Association for the use of blood glucose self monitoring according to current scientific evidence. PMID: 30980155 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Wascher TC, Stechemesser L, Harreiter J, den Ausschuss Leitlinien Tags: Wien Klin Wochenschr Source Type: research

[Inhibition of platelet aggregation (Update 2019)].
Abstract Acute thrombotic complications as a key feature of accelerated atherothrombotic disease typically precipitate cardiovascular events and therefore strongly contribute to cardiovascular morbidity and mortality in diabetic patients. Inhibition of platelet aggregation can reduce the risk for acute atherothrombosis. The present article represents the recommendations of the Austrian Diabetes Association for the use of antiplatelet drugs in diabetic patients according to current scientific evidence. PMID: 30980156 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Wascher TC, Saely CH, den Ausschuss Leitlinien Tags: Wien Klin Wochenschr Source Type: research

[Lipids-Diagnosis and therapy in diabetes mellitus (Update 2019)].
ien Abstract Hyper- and dyslipidemia contribute to cardiovascular morbidity and mortality in diabetic patients. Pharmacological therapy to lower LDL cholesterol has convincingly shown to reduce cardiovascular risk in diabetic patients. The present article represents the recommendations of the Austrian Diabetes Association for the use of lipid-lowering drugs in diabetic patients according to current scientific evidence. PMID: 30980157 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Wascher TC, Paulweber B, Toplak H, Saely CH, Drexel H, Föger B, Hoppichler F, Stulnig T, Stingl H, Clodi M, den Ausschuss Leitlinien Tags: Wien Klin Wochenschr Source Type: research

[Migration and diabetes (Update 2019)].
Abstract The article deals with the demographic data of migration in Austria and with therapeutic advice concerning drug therapy and diabetes education for patients with migration background. In this context sociocultural specifics are discussed. These suggestions are seen complementary to the general treatment guidelines of the Austrian Diabetes Association.The fasting month Ramadan is widely practiced by the Muslim population worldwide. Ensuring the optimal care of the many people with diabetes who fast during Ramadan is crucial. The IDF-DAR Practical Guidelines (International Diabetes Federation - Diabetes and ...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Aydinkoc-Tuzcu K, Schindler K, Sat S, Berger F, Ludvik B, Fasching P Tags: Wien Klin Wochenschr Source Type: research

[Diagnosis, treatment and monitoring of diabetic eye disease (Update 2019)].
aft Abstract Diabetes mellitus can cause diabetic retinopathy, diabetic macular edema, optic neuropathy, cataract or dysfunction of the eye muscles. The incidence of these defects correlates with disease duration and quality of metabolic control. Recommendations of the Austrian Diabetes Association for diagnosis, therapeutic procedures and requirements for adequate follow-up depending on stage of diabetic eye disease are summarized. PMID: 30980159 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Radda S, Bolz M, Egger S, Gasser-Steiner V, Kralinger M, Mennel S, Scholda C, Stolba U, Wedrich A, die Netzhautkommission der Österreichischen Ophthalmologischen Gesellschaft Tags: Wien Klin Wochenschr Source Type: research

[Treatment of acute diabetic metabolic crises in adults (Update 2019) : Hyperglycemic hyperosmolar state and ketoacidotic metabolic disorders].
er A Abstract Diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state (HHS) represent potentially life-threatening situations in adults. Therefore, rapid comprehensive diagnostic and therapeutic measures with close monitoring of vital and laboratory parameters are required. The treatment of DKA and HHS is essentially the same and replacement of the mostly substantial fluid deficit with several liters of a physiological crystalloid solution is the first and most important step. Serum potassium concentrations need to be carefully monitored to guide its substitution. Regular insulin or rapid acting ...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Kaser S, Sourij H, Clodi M, Schneeweiß B, Laggner AN, Luger A Tags: Wien Klin Wochenschr Source Type: research

[Diabetes education and counselling in adult patients with diabetes (Update 2019)].
Abstract Diabetes education and self-management play a critical role in diabetes care. Patient empowerment aims to actively influence the course of the disease by self-monitoring and subsequent treatment modification as well as the ability of patients to integrate diabetes into their daily life and to appropriately adapt it to their life style situation. Diabetes education has to be made accessible for all persons with the disease. In order to be able to provide a structured and validated education program, adequate personnel as well as space, organizational and financial prerequisites are required. Besi...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Weitgasser R, Clodi M, Cvach S, Riedl M, Lechleitner M, Ludvik B Tags: Wien Klin Wochenschr Source Type: research

[Hospital diabetes management (Update 2019)].
Abstract This position statement presents the recommendations of the Austrian Diabetes Association for diabetes management of adult patients during inpatient stay. It is based on the current evidence with respect to blood glucose targets, insulin therapy and treatment with oral antidiabetic drugs during inpatient hospitalization. Additionally, special circumstances such as intravenous insulin therapy, concomitant therapy with glucocorticoids and use of diabetes technology during hospitalization are discussed. PMID: 30980162 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Mader JK, Brix J, Aberer F, Vonbank A, Resl M, Pieber TR, Stechemesser L, Sourij H Tags: Wien Klin Wochenschr Source Type: research

[Clinical practice recommendations for diabetes in pregnancy (Update 2019)].
r M Abstract In 1989 the St. Vincent Declaration aimed to achieve comparable pregnancy outcomes in diabetic and non-diabetic women. However, currently women with pre-gestational diabetes still feature a higher risk of perinatal morbidity and even increased mortality. This fact is mostly ascribed to a persistently low rate of pregnancy planning and pre-pregnancy care with optimization of metabolic control prior to conception. All women should be experienced in the management of their therapy and on stable glycemic control prior to the conception. In addition, thyroid dysfunction, hypertension as well as t...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Kautzky-Willer A, Harreiter J, Winhofer-Stöckl Y, Weitgasser R, Lechleitner M Tags: Wien Klin Wochenschr Source Type: research

[Other specific types of diabetes and exocrine pancreatic insufficiency (Update 2019)].
r A Abstract The heterogenous catagory "specific types of diabetes due to other causes" encompasses disturbances in glucose metabolism due to other endocrine disorders such as acromegaly or hypercortisolism, drug-induced diabetes (e. g. antipsychotic medications, glucocorticoids, immunosuppressive agents, highly active antiretroviral therapy (HAART)), genetic forms of diabetes (e. g. Maturity Onset Diabetes of the Young (MODY), neonatal diabetes, Down Syndrome, Klinefelter Syndrome, Turner Syndrome), pancreatogenic diabetes (e. g. postoperatively, pancreatitis, pancreatic cancer, haemochromatosis, ...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Kaser S, Winhofer-Stöckl Y, Kazemi-Shirazi L, Hofer SE, Brath H, Sourij H, Vila G, Abrahamian H, Riedl M, Weitgasser R, Resl M, Clodi M, Luger A Tags: Wien Klin Wochenschr Source Type: research

[Smoking, alcohol and diabetes (Update 2019)].
Abstract Smoking and second-hand smoke strongly increase incidence of diabetes and probability for its complications. Smoking cessation can lead to weight gain and increased diabetes risk; however, it decreases cardiovascular and total mortality. A basal diagnostics (Fagerström Test, exhaled CO) is the basis for successful smoking cessation. Supporting medication include Varenicline, Nicotine Replacement Therapy and Bupropion. Socio-economic as well as psychological factors play an important role for smoking and smoking cessation.Moderate consumption of alcohol possibly decreases risk for diabetes and ca...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Brath H, Kaser S, Tatschl C, Fasching P Tags: Wien Klin Wochenschr Source Type: research

[Lifestyle: physical activity and training as prevetion and therapy of type  2 diabetes mellitus (Update 2019)].
[Lifestyle: physical activity and training as prevetion and therapy of type 2 diabetes mellitus (Update 2019)]. Wien Klin Wochenschr. 2019 Apr 12;: Authors: Francesconi C, Niebauer J, Haber P, Weitgasser R, Lackinger C Abstract Lifestyle in general and particularly health enhancing physical activity is known to be an important component in the prevention and therapy of type 2 diabetes mellitus.To gain substantial health benefits a minimum of 150 min of moderate or vigorous intense aerobic physical activity and muscle strengthening activities per week are needed. Additionally, inactivi...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Francesconi C, Niebauer J, Haber P, Weitgasser R, Lackinger C Tags: Wien Klin Wochenschr Source Type: research

[Diagnosis and management of patients with diabetes and co-existing osteoporosis (Update 2019) : Common guideline of the Autrian Society for Bone and Mineral Research and the Austrian Diabetes Society].
schka J Abstract Fragility fractures are increasingly recognized as a complication of both type 1 and type 2 diabetes, with fracture risk that increases with disease duration and poor glycemic control. The identification and management of fracture risk in these patients remains challenging. This manuscript explores the clinical characteristics of bone fragility in adults with diabetes and highlights recent studies that have evaluated areal bone mineral density (BMD), bone microstructure and material properties, biochemical markers, and fracture prediction algorithms (FRAX) in these patients. It furt...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Muschitz C, Kautzky-Willer A, Rauner M, Winhöfer-Stöckl Y, Haschka J Tags: Wien Klin Wochenschr Source Type: research

[Mental disorders and diabetes mellitus (Update 2019)].
ak H Abstract Psychiatric disorders and psychological problems are common in patients with diabetes mellitus. There is a twofold increase in depression which is associated with suboptimal glycemic control and increased morbidity and mortality. Other psychiatric disorders with a higher incidence of diabetes mellitus are cognitive impairment, dementia, disturbed eating behavior, anxiety disorders, schizophrenia, bipolar disorders and borderline personality disorder. The coincidence of mental disorders and diabetes mellitus has unfavorable influences on metabolic control and micro- and macroangiopathic comp...
Source: Wiener Klinische Wochenschrift - April 12, 2019 Category: General Medicine Authors: Abrahamian H, Kautzky-Willer A, Rießland-Seifert A, Fasching P, Ebenbichler C, Kautzky A, Hofmann P, Toplak H Tags: Wien Klin Wochenschr Source Type: research