Perspectives in treatment-resistant depression: esketamine and electroconvulsive therapy
Wien Klin Wochenschr. 2024 Apr 17. doi: 10.1007/s00508-024-02358-w. Online ahead of print.ABSTRACTModern electroconvulsive therapy (ECT) and the approval of nasal esketamine for clinical use have significantly improved the approach to treatment-resistant depression (TRD), which is defined as non-response to at least two different courses of antidepressants with verified adherence to treatment, adequate dosage, and duration of treatment. The goal of this literature review is to present the newest evidence regarding efficacy and safety. Furthermore, we aim to provide an overview of future perspectives in this field of resear...
Source: Wiener Klinische Wochenschrift - April 25, 2024 Category: General Medicine Authors: Pia Baldinger-Melich Marie Spies Ina Bozic Siegfried Kasper Dan Rujescu Richard Frey Source Type: research

Perspectives in treatment-resistant depression: esketamine and electroconvulsive therapy
Wien Klin Wochenschr. 2024 Apr 17. doi: 10.1007/s00508-024-02358-w. Online ahead of print.ABSTRACTModern electroconvulsive therapy (ECT) and the approval of nasal esketamine for clinical use have significantly improved the approach to treatment-resistant depression (TRD), which is defined as non-response to at least two different courses of antidepressants with verified adherence to treatment, adequate dosage, and duration of treatment. The goal of this literature review is to present the newest evidence regarding efficacy and safety. Furthermore, we aim to provide an overview of future perspectives in this field of resear...
Source: Wiener Klinische Wochenschrift - April 25, 2024 Category: General Medicine Authors: Pia Baldinger-Melich Marie Spies Ina Bozic Siegfried Kasper Dan Rujescu Richard Frey Source Type: research

The Landsteiner lung cancer research platform (LALUCA) : Objectives, methodology and implementation of a  real-world clinical lung cancer registry
CONCLUSION: The LALUCA registry is a web-based platform for the collection of real-world clinical data of lung cancer patients. Combining a large number of patients with a focus on gathering comprehensive data on diagnosis and treatment, the LALUCA registry provides a tool for investigation, evaluation, and improvement of the clinical management, survival and quality of care of Austrian lung cancer patients.PMID:38652311 | DOI:10.1007/s00508-024-02351-3 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 23, 2024 Category: General Medicine Authors: Anna Lang-St öberl Hannah Fabikan Maximilan Hochmair Klaus Kirchbacher Vikaela Mania Rodriguez Leya Ay Christoph Weinlinger David Rosenthaler Oliver Illini Nino M üser Georg-Christian Funk Arschang Valipour Source Type: research

Reply to comments on: "Efficacy of cx601 (darvadstrocel) for the treatment of perianal fistulizing Crohn's disease-A  prospective nationwide multicenter cohort study"
Wien Klin Wochenschr. 2024 Apr 23. doi: 10.1007/s00508-024-02363-z. Online ahead of print.NO ABSTRACTPMID:38652312 | DOI:10.1007/s00508-024-02363-z (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 23, 2024 Category: General Medicine Authors: Stefan Riss Christopher Dawoud Source Type: research

External quality assessments for SARS-CoV-2 genome detection in Austria : A  comparison of the first postpandemic round with results from the pandemic era
CONCLUSION: Overall ratios of true positive results were below the mean of all results during the pandemic but were similar to the first round of the pandemic. A lower post-pandemic true positive ratio was associated with specific laboratory types and assay formats, particularly for samples with low concentration. The EQAs will continue to monitor the laboratory performance to ensure the same quality of epidemiological data after the pandemic, even if vigilance has decreased.PMID:38653873 | DOI:10.1007/s00508-024-02353-1 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 23, 2024 Category: General Medicine Authors: Christoph Buchta Stephan W Aberle Irene G örzer Andrea Griesmacher Mathias M M üller Erich Neuwirth Elisabeth Puchhammer-St öckl Lukas Weseslindtner Jeremy V Camp Source Type: research

The Landsteiner lung cancer research platform (LALUCA) : Objectives, methodology and implementation of a  real-world clinical lung cancer registry
CONCLUSION: The LALUCA registry is a web-based platform for the collection of real-world clinical data of lung cancer patients. Combining a large number of patients with a focus on gathering comprehensive data on diagnosis and treatment, the LALUCA registry provides a tool for investigation, evaluation, and improvement of the clinical management, survival and quality of care of Austrian lung cancer patients.PMID:38652311 | DOI:10.1007/s00508-024-02351-3 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 23, 2024 Category: General Medicine Authors: Anna Lang-St öberl Hannah Fabikan Maximilan Hochmair Klaus Kirchbacher Vikaela Mania Rodriguez Leya Ay Christoph Weinlinger David Rosenthaler Oliver Illini Nino M üser Georg-Christian Funk Arschang Valipour Source Type: research

Reply to comments on: "Efficacy of cx601 (darvadstrocel) for the treatment of perianal fistulizing Crohn's disease-A  prospective nationwide multicenter cohort study"
Wien Klin Wochenschr. 2024 Apr 23. doi: 10.1007/s00508-024-02363-z. Online ahead of print.NO ABSTRACTPMID:38652312 | DOI:10.1007/s00508-024-02363-z (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 23, 2024 Category: General Medicine Authors: Stefan Riss Christopher Dawoud Source Type: research

External quality assessments for SARS-CoV-2 genome detection in Austria : A  comparison of the first postpandemic round with results from the pandemic era
CONCLUSION: Overall ratios of true positive results were below the mean of all results during the pandemic but were similar to the first round of the pandemic. A lower post-pandemic true positive ratio was associated with specific laboratory types and assay formats, particularly for samples with low concentration. The EQAs will continue to monitor the laboratory performance to ensure the same quality of epidemiological data after the pandemic, even if vigilance has decreased.PMID:38653873 | DOI:10.1007/s00508-024-02353-1 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 23, 2024 Category: General Medicine Authors: Christoph Buchta Stephan W Aberle Irene G örzer Andrea Griesmacher Mathias M M üller Erich Neuwirth Elisabeth Puchhammer-St öckl Lukas Weseslindtner Jeremy V Camp Source Type: research

Masqueraded sebaceous gland carcinoma of the lower eyelid in a  young pregnant patient
Wien Klin Wochenschr. 2024 Apr 18. doi: 10.1007/s00508-024-02349-x. Online ahead of print.ABSTRACTThe purpose of this case report is to present misdiagnosed sebaceous gland carcinoma of the lower eyelid with rapid growth in a young woman during pregnancy. Eyelid sebaceous gland carcinoma is a relatively rare tumor and a disease primarily of older patients. It occurs more commonly in oriental populations and with a predilection for the upper eyelid. Early diagnosis and appropriate treatment may help improve disease control and patient survival.PMID:38634909 | DOI:10.1007/s00508-024-02349-x (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 18, 2024 Category: General Medicine Authors: Karla Randelovic Ivanka Petric Vickovic Valentina Lacmanovic Loncar Leo Pazanin Anita Pusic Sesar Renata Ivekovic Zoran Vatavuk Source Type: research

40  years neonatology : An academic life
CONCLUSION: As we look ahead it is imperative to build upon the progress made, harnessing the power of science and technology to further improve the survival and quality of life for preterm infants in Austria and worldwide. At the same time, neonatology must continue to prioritize ethical reflection and education, fostering a culture of integrity, interdisciplinary collaboration, and the development of guidelines and protocols that uphold ethical standards while addressing the evolving needs and complexities of neonatal medicine.PMID:38634910 | DOI:10.1007/s00508-024-02360-2 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 18, 2024 Category: General Medicine Authors: Arnold Pollak Source Type: research

MUW researcher of the month
Wien Klin Wochenschr. 2024 Apr;136(7-8):247-248. doi: 10.1007/s00508-024-02352-2.NO ABSTRACTPMID:38598111 | DOI:10.1007/s00508-024-02352-2 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 10, 2024 Category: General Medicine Source Type: research

Die Gesundheitsreform: Positives und Negatives
Wien Klin Wochenschr. 2024 Apr;136(7-8):249. doi: 10.1007/s00508-024-02354-0.NO ABSTRACTPMID:38598112 | DOI:10.1007/s00508-024-02354-0 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 10, 2024 Category: General Medicine Source Type: research

Fortbildungen der Österreichischen Gesellschaft für Pneumologie
Wien Klin Wochenschr. 2024 Apr;136(7-8):250. doi: 10.1007/s00508-024-02356-y.NO ABSTRACTPMID:38598113 | DOI:10.1007/s00508-024-02356-y (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 10, 2024 Category: General Medicine Source Type: research

Comments on: "Efficacy of cx601 (darvadstrocel) for the treatment of perianal fistulizing Crohn's disease-A  prospective nationwide multicenter cohort study"
Wien Klin Wochenschr. 2024 Apr 10. doi: 10.1007/s00508-024-02359-9. Online ahead of print.NO ABSTRACTPMID:38600334 | DOI:10.1007/s00508-024-02359-9 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 10, 2024 Category: General Medicine Authors: Man-Ling Ye Fang Cheng Source Type: research

MUW researcher of the month
Wien Klin Wochenschr. 2024 Apr;136(7-8):247-248. doi: 10.1007/s00508-024-02352-2.NO ABSTRACTPMID:38598111 | DOI:10.1007/s00508-024-02352-2 (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 10, 2024 Category: General Medicine Source Type: research