Impact of literature reports on drug safety signals.
CONCLUSION: This study underlines the importance of scientific literature for the signal management process in addition to other data sources. Most literature ICSRs from this analysis were created based on scientific journals indexed in bibliographic databases; therefore, it can be concluded that a systematic review of bibliographic databases, such as Embase or MEDLINE is highly relevant for the signal management process. PMID: 32458200 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 26, 2020 Category: General Medicine Authors: Ochyra B, Szewczyk M, Przybylkowski A Tags: Wien Klin Wochenschr Source Type: research

The impact of total body water on breath alcohol calculations.
This study describes mean elimination rates of BrAC for both men (0.065 ± 0.011 mg/L h-1) and women (0.074 ± 0.017 mg/L h-1). As previously shown women displayed a significantly higher elimination rate than men (p = 0.006). PMID: 32451818 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 25, 2020 Category: General Medicine Authors: Reiter GS, Boeckle M, Reiter C, Seltenhammer MH Tags: Wien Klin Wochenschr Source Type: research

Nutritional status and its effect on complications in patients with colorectal cancer.
CONCLUSION: Malnourished patients, as identified by the PG-SGA score, stayed longer in hospital than patients who were not malnourished, while increased BMI was recognized as a risk factor for wound dehiscence. PMID: 32451819 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 25, 2020 Category: General Medicine Authors: Karin M, Bogut A, Hojsak I, Babić E, Volarić M, Bevanda M Tags: Wien Klin Wochenschr Source Type: research

Low dose intravenous immunoglobulin in addition to cyclophosphamide in systemic sclerosis : Single centre experience.
CONCLUSION: The results of the study suggest that IVIG may be an additional treatment option together with CYC for patients for whom other therapies have failed, but further studies on the exact role of IVIG in the treatment of severe SSc are required. PMID: 32451820 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 25, 2020 Category: General Medicine Authors: Perković D, Petrić M, Božić I, Borić K, Marasović Krstulović D, Radić M, Martinović Kaliterna D Tags: Wien Klin Wochenschr Source Type: research

Diabetes and COVID-19 : Disease-Management-People.
Abstract The current pandemic of SARS-CoV‑2 coronavirus disease 2019 (COVID-19) is a particular challenge for diabetes patients. Diabetes mellitus predisposes to a particularly severe course of the disease and doubles the COVID-19 mortality risk due to pulmonary and cardiac involvement. In addition, diabetes patients often suffer from comorbidities which further worsen clinical outcomes. Glycemic control during infectious diseases is often suboptimal, and antidiabetic drugs and insulin therapy have to be adapted accordingly. On the other hand, access of diabetes patients to outpatient clinics are limit...
Source: Wiener Klinische Wochenschrift - May 20, 2020 Category: General Medicine Authors: Peric S, Stulnig TM Tags: Wien Klin Wochenschr Source Type: research

Recommendations for driving after implantable cardioverter defibrillator implantation and the use of a  wearable cardioverter defibrillator : Different viewpoints around the world.
Recommendations for driving after implantable cardioverter defibrillator implantation and the use of a wearable cardioverter defibrillator : Different viewpoints around the world. Wien Klin Wochenschr. 2020 May 20;: Authors: Cooper M, Berent T, Auer J, Berent R Abstract The use of implantable cardioverter defibrillators (ICD) has been shown to improve survival in patients at risk of sudden cardiac death; however, due to the continuous risk of sudden loss of consciousness during arrhythmia or ICD intervention, they pose a potential risk to other road users while driving. A large number o...
Source: Wiener Klinische Wochenschrift - May 20, 2020 Category: General Medicine Authors: Cooper M, Berent T, Auer J, Berent R Tags: Wien Klin Wochenschr Source Type: research

Sedentary behavior and kidney function in adults: a  narrative review.
Sedentary behavior and kidney function in adults: a narrative review. Wien Klin Wochenschr. 2020 May 20;: Authors: Volaklis K, Mamadjanov T, Meisinger C Abstract There is increasing evidence for an association between SB and CKD, an emerging public health problem particularly affecting old people. For this reason a systematic literature search was carried out in Embase and PubMed (Jan 2000-Dec 2018) looking for an association between SB and kidney function. A total of 10 studies met the inclusion criteria (7 cross-sectional and 3 longitudinal investigations). A sedentary lifes...
Source: Wiener Klinische Wochenschrift - May 20, 2020 Category: General Medicine Authors: Volaklis K, Mamadjanov T, Meisinger C Tags: Wien Klin Wochenschr Source Type: research

COVID-19: a  primer for healthcare providers.
COVID-19: a primer for healthcare providers. Wien Klin Wochenschr. 2020 May 20;: Authors: Bearden DM, Aiken PB, Cheng YH, Mai E, Peters TM Abstract According to the World Health Organization (WHO) the China office was first notified of cases of atypical pneumonia in Wuhan City on 31 December 2019. A viral genome sequence of a novel coronavirus, currently termed SARS-CoV‑2, with a disease process called COVID-19 was released 1 week later via online resources to obtain public health support in control of spread. Since then, the virus rapidly evolved into a global pandemic. The...
Source: Wiener Klinische Wochenschrift - May 20, 2020 Category: General Medicine Authors: Bearden DM, Aiken PB, Cheng YH, Mai E, Peters TM Tags: Wien Klin Wochenschr Source Type: research

Multimethod assessing the prognosis affecting factors of hospitalized children with burns in Zunyi, southwest China.
CONCLUSION: In southwest China children under 3 years old, scald burns are most common, and most burns occur at home. It seems that TBSA, skin grafting, age and burn depth are best predictors of the prognosis in hospitalized children with burns. PMID: 32435871 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 20, 2020 Category: General Medicine Authors: Li X, Wang X, Wang T, Yu H, Zhou Y, Wang H, Shi X Tags: Wien Klin Wochenschr Source Type: research

Combination value of biomarkers in discriminating adult onset still's disease and sepsis.
Abstract BACKGROUND: Lymphocyte and plateletcrit (PCT) as proportions of routine complete blood count tests, have been studied as simple biomarkers for inflammatory diseases. The aim of our study was to investigate whether blood routine parameters, especially platelet parameters could be a useful tool to distinguish Adult onset Still's disease (AOSD) from sepsis. METHODS: We retrospectively reviewed 58 patients with AOSD and 55 sepsis patients diagnosed at the First Affiliated Hospital of Nanjing Medical University between January, 2015 to December 2018. Laboratory data including ferritin, bloo...
Source: Wiener Klinische Wochenschrift - May 20, 2020 Category: General Medicine Authors: Zhang M, Xie M, Wang Y, Li J, Zhou J Tags: Wien Klin Wochenschr Source Type: research

Particular findings on lung CT in patients undergoing immunotherapy for bronchogenic carcinoma.
CONCLUSION: Management of patients with NSCLC using immune checkpoint inhibitors requires a knowledge of specific clinical and radiological findings. Both oncologists and radiologists have to be aware of the most common types, including atypical response patterns, such as a sarcoid-like reaction and pseudoprogression as well as of the pulmonary side effects that can encompass pneumonitis. PMID: 32430613 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 20, 2020 Category: General Medicine Authors: Beer L, Hochmair M, Kifjak D, Haug AR, Prayer F, Mayerhoefer ME, Herold C, Prosch H Tags: Wien Klin Wochenschr Source Type: research

Interoceptive awareness and self-regulation contribute to psychosomatic competence as measured by a new inventory.
CONCLUSION: Interoceptive awareness and conscious body-related self-regulation seem to jointly contribute to a basic competence which may serve homeostatic/allostatic control; however, further research is needed to confirm the reported preliminary findings in a large-scale test. PMID: 32430611 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 19, 2020 Category: General Medicine Authors: Fazekas C, Avian A, Noehrer R, Matzer F, Vajda C, Hannich H, Neubauer A Tags: Wien Klin Wochenschr Source Type: research

Incidence of thyroid disorders in the second decade of adequate iodine supply in Slovenia.
CONCLUSION: In the second decade of adequate iodine supply in Slovenia, we established a similar or even a lower incidence of most thyroid diseases in the observed 4 years with the exception of Hashimoto's thyroiditis. PMID: 32377868 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 6, 2020 Category: General Medicine Authors: Gaberšček S, Gaberšček B, Zaletel K Tags: Wien Klin Wochenschr Source Type: research

HbA1c level decreases in iron deficiency anemia.
Tetiker T Abstract BACKGROUND: Hemoglobin A1c (HbA1c) is the major form of glycosylated hemoglobin. There are conflicting data on changes in HbA1c levels in patients with iron deficiency anemia (IDA). The present study aimed to investigate the effects of HbA1c levels in the presence of IDA, the effects of iron treatment on HbA1c levels, as well as the relationship between the severity of anemia and HbA1c levels in patients without diabetes. DESIGN AND METHODS: A total of 263 patients without diabetes mellitus (DM) who were admitted to Cukurova University, Faculty of Medicine, Department of Endocrinology ...
Source: Wiener Klinische Wochenschrift - May 6, 2020 Category: General Medicine Authors: Çetinkaya Altuntaş S, Evran M, Gürkan E, Sert M, Tetiker T Tags: Wien Klin Wochenschr Source Type: research

Herpes zoster and Brown-S équard syndrome.
Herpes zoster and Brown-Séquard syndrome. Wien Klin Wochenschr. 2020 May 05;: Authors: Garbi A, Rauer F, Heckmann JG PMID: 32372115 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - May 5, 2020 Category: General Medicine Authors: Garbi A, Rauer F, Heckmann JG Tags: Wien Klin Wochenschr Source Type: research

Detection of atrial shunt lesions with a  single echocardiographic parameter.
This study was carried out to evaluate the accuracy of the single parameter right ventricular outflow tract (RVOT) velocity time integral (VTI) to identify atrial shunt lesions. METHODS: All patients who underwent transesophageal echocardiography (TEE) examination at this institution between 1 January 2013 and 1 January 2018 were retrospectively analyzed. The RVOT-VTI was measured in the transthoracic echocardiography performed immediately before each TEE. The diagnostic accuracy for detection of atrial shunt lesions was tested. RESULTS: A total of 2797 patients with a median age of 67 years (interquart...
Source: Wiener Klinische Wochenschrift - April 30, 2020 Category: General Medicine Authors: Dannenberg V, Goliasch G, Hengstenberg C, Binder T, Gabriel H, Schneider M Tags: Wien Klin Wochenschr Source Type: research

Influence of pancreatic status, CFTR mutations, Staphylococcus aureus and/or Pseudomonas aeruginosa infection/colonization on lung function in cystic fibrosis during a  2-year follow-up period.
CONCLUSION: In CF, deterioration of lung function as evaluated by spirometry was continuous and varied according to sex, pancreatic insufficiency, and severe CFTR mutations. No differences were observed between groups in terms of predominant type of bacteria, but the reduction of spirometry parameters was significant in the predominantly S. aureus and concomitant infection groups. PMID: 32356101 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 30, 2020 Category: General Medicine Authors: Pascoal MA, Marson FAL, Paschoal IA, Levy CE Tags: Wien Klin Wochenschr Source Type: research

Modern diagnostics in emergency medicine.
s H PMID: 32356102 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 30, 2020 Category: General Medicine Authors: Niederdöckl J, Buchtele N, Schwameis M, Domanovits H Tags: Wien Klin Wochenschr Source Type: research

[Breast reconstruction following cancer].
rfer KF PMID: 32347375 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 28, 2020 Category: General Medicine Authors: Bergmeister KD, Rohrbacher A, Flores T, Bachner MG, Götzinger P, Schrögendorfer KF Tags: Wien Klin Wochenschr Source Type: research

Plasma lipids in patients with inflammatory bowel disease : Observations on the associations between lipid indices and coronary flow reserve.
This study was conducted to investigate the association of lipid parameters and indices with coronary flow reserve and markers of inflammation in IBD patients. METHODS: A total of 73 patients with IBD and 26 healthy controls were enrolled. Patients in the IBD arm were either in remission or had mild disease activity. Lipid parameters, C‑reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were analyzed using standard laboratory techniques. Coronary flow reserve (CFR) was measured using two-dimensional echocardiography. RESULTS: Both CRP and ESR were higher and CFR was significantly low...
Source: Wiener Klinische Wochenschrift - April 28, 2020 Category: General Medicine Authors: Kul Ş, Çalışkan Z, Güvenç TS, Güvenç RÇ, Çalışkan M Tags: Wien Klin Wochenschr Source Type: research

Frailty as a  predictor of all-cause mortality and readmission in older patients with acute coronary syndrome : A systematic review and meta-analysis.
CONCLUSIONS: Both frailty and pre-frailty are risk factors for all-cause mortality and readmission in older patients with ACS. Therefore, frailty assessment should be given sufficient attention in the management of older patients with ACS to help improve survival and reduce readmission rate. PMID: 32342196 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 27, 2020 Category: General Medicine Authors: Xu W, Cai Y, Liu H, Fan L, Wu C Tags: Wien Klin Wochenschr Source Type: research

Management and outcome of traumatic subdural hematoma in 47  infants and children from a single center.
CONCLUSION: The results of this study confirmed that pediatric SDH is a rare, but serious condition. Despite a poor prognosis, most patients could be treated with good outcomes, given that the choice of treatment is correct. TRIAL REGISTRATION: Research registry 2686. PMID: 32333270 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 24, 2020 Category: General Medicine Authors: Binder H, Tiefenboeck TM, Majdan M, Komjati M, Schuster R, Hajdu S, Leitgeb J Tags: Wien Klin Wochenschr Source Type: research

Vaccine hesitancy : Report of a  student study group.
Vaccine hesitancy : Report of a student study group. Wien Klin Wochenschr. 2020 Apr 22;: Authors: Weitz L, Bellach L, Faltum A, Berger A, Maurer W Abstract In summer 2019 an extracurricular activity was started at the Medical University of Vienna (MUW) with the title: "Esoterism in Medicine", where different chapters were evaluated by students. Here we present the subheading "Vaccine Hesitancy". Three students formulated arguments from sceptic, hesitant or anti-vaccine groups and discussed the scientific literature to rebut it. Frequent objections were partly taken from the ho...
Source: Wiener Klinische Wochenschrift - April 22, 2020 Category: General Medicine Authors: Weitz L, Bellach L, Faltum A, Berger A, Maurer W Tags: Wien Klin Wochenschr Source Type: research

Silicone soft socket system for the treatment of geriatic transtibial amputees.
Abstract BACKGROUND: Outfitting geriatric amputees with a suitable prosthesis is a demanding task. The aim of this study was to determine the effect of prostheses outfitted with a silicone suspension interface system on a large group of transtibial amputees regarding walking distance, satisfaction of use and duration of daily use. METHODS: The study included 75 mostly geriatric transtibial amputees fitted with a rigid total contact socket with a silicone interface system called an Icelandic roll-on silicone socket (ICEROSS, Ossur, Reykjavik, Iceland). At follow-up 54 pa...
Source: Wiener Klinische Wochenschrift - April 16, 2020 Category: General Medicine Authors: Breuer R, Trieb K Tags: Wien Klin Wochenschr Source Type: research

Serum procalcitonin in Philadelphia-negative myeloproliferative neoplasms.
This study investigated PCT in 41 ambulatory MPN patients (13 ET, 13 PV and 15 MF) who had no signs of infection and compared it to 10 MPN patients with microbiologically and/or serologically documented bacterial infections. Median PCT in MPN patients was 0.02 ng/mL (range 0.01-0.09 ng/mL). No difference in PCT was found between ET, PV and MF patients (p = 0.993), whereas MPN patients with documented bacterial infections had significantly higher PCT (median PCT 2.45, range 0.90-5.40 ng/mL) when compared to MPN patients with (median PCT 0.03 ng/mL) or without constitutional symptoms...
Source: Wiener Klinische Wochenschrift - April 16, 2020 Category: General Medicine Authors: Krečak I, Peran N, Lapić I, Gverić-Krečak V, Krečak F, Rončević P, Duraković N Tags: Wien Klin Wochenschr Source Type: research

Leprosy in a  low-incidence setting : Case report relevant to metagenomic next generation sequencing applications.
Leprosy in a low-incidence setting : Case report relevant to metagenomic next generation sequencing applications. Wien Klin Wochenschr. 2020 Apr 14;: Authors: Quan M, Liu L, Zhou T, Jiang Y, Wang X, Zong Z Abstract Leprosy is a disease caused by Mycobacterium leprae that results in disability. In 2000 the World Health Organization announced that leprosy had been eradicated. In nonendemic areas diagnosing leprosy is becoming a challenge for inexperienced clinicians. This case involves a male patient suffering from chronic numbness, hand deformity and recurrent erythema. Skin biopsy ...
Source: Wiener Klinische Wochenschrift - April 14, 2020 Category: General Medicine Authors: Quan M, Liu L, Zhou T, Jiang Y, Wang X, Zong Z Tags: Wien Klin Wochenschr Source Type: research

Nature's endless wonder: unexpected motherhood after pediatric allogeneic stem cell transplantation and severe late effects.
This article describes the case of a young woman who received polychemotherapy and total body irradiation (TBI) containing conditioning for HSCT for a relapsed anaplastic large cell lymphoma (ALCL). She developed severe sclerotic chronic graft-versus-host disease (GVHD) with irreversible joint contractures and multiorgan involvement, requiring long-term multimodal immunosuppressive treatment. Subsequently showing a considerable number of LE including hypergonadotropic hypogonadism, she accepted that infertility would be quite likely. Her courageous personal life planning included part-time working and a ...
Source: Wiener Klinische Wochenschrift - April 7, 2020 Category: General Medicine Authors: Bauer D, Tüchler R, Dörfler D, Lawitschka A Tags: Wien Klin Wochenschr Source Type: research

Fallacies of esoteric medicine.
PMID: 32253626 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 6, 2020 Category: General Medicine Authors: Ernst E Tags: Wien Klin Wochenschr Source Type: research

Correction to: Knock-on effect of periodontitis to the pathogenesis of Alzheimer's disease?
Abstract The original version of this article unfortunately contained a mistake. There was an error in Fig. 2. The original article has been corrected. We apologize for the mistake.The correct Fig. 2 is given …. PMID: 32253627 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - April 6, 2020 Category: General Medicine Authors: Leblhuber F, Huemer J, Steiner K, Gostner JM, Fuchs D Tags: Wien Klin Wochenschr Source Type: research

Psychometric properties of the Activities Ccale for Kids-performance after allogeneic hematopoietic stem cell transplantation in adolescents and children : Results of a  prospective study on behalf of the German-Austrian-Swiss GVHD Consortium.
Psychometric properties of the Activities Ccale for Kids-performance after allogeneic hematopoietic stem cell transplantation in adolescents and children : Results of a prospective study on behalf of the German-Austrian-Swiss GVHD Consortium. Wien Klin Wochenschr. 2020 Apr 03;: Authors: Lawitschka A, Brunmair M, Bauer D, Zubarovskaya N, Felder-Puig R, Strahm B, Bader P, Strauss G, Albert M, von Luettichau I, Greinix H, Wolff D, Peters C Abstract BACKGROUND: The psychometric properties of an instrument, the Activity Scale for Kids-performance (ASKp), were assessed which was proposed to capture phy...
Source: Wiener Klinische Wochenschrift - April 3, 2020 Category: General Medicine Authors: Lawitschka A, Brunmair M, Bauer D, Zubarovskaya N, Felder-Puig R, Strahm B, Bader P, Strauss G, Albert M, von Luettichau I, Greinix H, Wolff D, Peters C Tags: Wien Klin Wochenschr Source Type: research

Evaluation of the Manchester triage system for patients with acute coronary syndrome.
In this study 282 patients with ACS (STEMI: 34.0%, N‑STEMI: 61.7%, UAP: 4.3%) were triaged as MTS level 1 (immediate assessment): 0.4%, MTS level 2 (very urgent): 51.4%, MTS level 3 (urgent): 41.5%, MTS level 4 (standard): 6.7%, MTS level 5 (non-urgent): 0%. We observed significantly lower mean MTS levels in males (male: 2.48 ± 0.59, female: 2.68 ± 0.68, p = 0.02) and in patients younger than 80 years (age
Source: Wiener Klinische Wochenschrift - April 2, 2020 Category: General Medicine Authors: Kiblboeck D, Steinrueck K, Nitsche C, Lang W, Kellermair J, Blessberger H, Steinwender C, Siostrzonek P Tags: Wien Klin Wochenschr Source Type: research

Univ.-Prof. Dr. Helmut Sinzinger (1948-2020).
PMID: 32219542 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - March 26, 2020 Category: General Medicine Authors: College of Physicians in Vienna, Volc-Platzer B Tags: Wien Klin Wochenschr Source Type: research

Association between 6  min pegboard and ring test and arm performance in GOLD stage II-III patients.
This study included 40 stable patients with COPD. All participants underwent the 6PBRT, peripheral venous blood sampling, arm ergometer test and the Glittre-ADL and ADL simulation tests for the ADLs performance. RESULTS: An average 172.51 ± 25.94 rings were moved in 6 min. The number of rings in 6PBRT was significantly positively correlated with the number of cycles in ADL simulation test (r = 0.553, p 
Source: Wiener Klinische Wochenschrift - March 25, 2020 Category: General Medicine Authors: Calik-Kutukcu E, Arikan H, Vardar-Yagli N, Saglam M, Inal-Ince D, Oksuz C, Savci S, Duger T, Coplu L Tags: Wien Klin Wochenschr Source Type: research

Knock-on effect of periodontitis to the pathogenesis of Alzheimer's disease?
In this study, 20 consecutive patients with probable Alzheimer's disease were investigated. Diagnosis was established by cognitive tests, routine laboratory tests and cerebral magnetic resonance tomography. In 35% of these patients with cognitive impairment pathogenic periodontal bacteria were found. RESULTS: The presence of Porphyromonas gingivalis, the key pathogen and one of the species involved in chronic periodontitis, was found to be associated with lower mini mental state examination scores (p 
Source: Wiener Klinische Wochenschrift - March 25, 2020 Category: General Medicine Authors: Leblhuber F, Huemer J, Steiner K, Gostner JM, Fuchs D Tags: Wien Klin Wochenschr Source Type: research

From St. John's wort to tomato and from Rhodiola to cranberry : A  review of phytotherapy and some examples.
CONCLUSION: The findings were diverse and must be individually taken into account. Evidence for efficacy varies within and between the four examples. An explanation for the lack of reproducibility of findings from preclinical and clinical experiments might be the insufficient standardization of herbal medicines. There is no scientific reason why phytotherapy should not be investigated with the same rigor as conventional drugs to establish the efficacy and potential risks. Meanwhile, it is concluded that care is essential when using herbal medicine in the daily routine and informing patients about potential shortcomings and...
Source: Wiener Klinische Wochenschrift - March 24, 2020 Category: General Medicine Authors: Weixlbaumer V, Draxler L, Zeitlinger M, Prantl B Tags: Wien Klin Wochenschr Source Type: research

Medical practice and placebo response: an inseparable bond?
Conclusion: Placebo and nocebo are both underestimated and underresearched in their value. Through further investigation doctors could strengthen the placebo response and prevent adverse effects to help their patients at low cost. These techniques would benefit the patient-doctor relationship, which is the alter of a trust-based successful therapy. PMID: 32211987 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - March 24, 2020 Category: General Medicine Authors: Jilch S, Sel R, Shariat SF Tags: Wien Klin Wochenschr Source Type: research

A  critical examination of the main premises of Traditional Chinese Medicine.
This article therefore provides an overview of the evidence underlying the basic TCM concepts, such as Qi, meridians, acupuncture, pulse and tongue diagnostics as well as traditional herbal treatments. Moreover, it discusses whether scientific literature on TCM reflects the current standard for evidence-based research, as described in good scientific practice and good clinical practice guidelines. Importantly, misinformation regarding the therapeutic efficacy of animal-derived substances has lead and currently leads to problems with wildlife preservation and animal ethics. Nevertheless, the (re-)discovery of artemisin...
Source: Wiener Klinische Wochenschrift - March 20, 2020 Category: General Medicine Authors: Eigenschink M, Dearing L, Dablander TE, Maier J, Sitte HH Tags: Wien Klin Wochenschr Source Type: research

Statistically significant but clinically irrelevant correlation?
PMID: 32189118 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - March 18, 2020 Category: General Medicine Authors: Yang L, Waldhoer T Tags: Wien Klin Wochenschr Source Type: research

Can measuring passive neck muscle stiffness in whiplash injury patients help detect false whiplash claims?
This study included 75 whiplash injury patients and 75 control subjects. Trapezius, splenius capitis and sternocleidomastoid muscles were examined by ultrasound shear wave elastography. RESULTS: Increased muscle stiffness was noticed in trapezius muscle bilaterally in the whiplash group when compared to the control group (p 
Source: Wiener Klinische Wochenschrift - March 18, 2020 Category: General Medicine Authors: Aljinović J, Barišić I, Poljičanin A, Kuzmičić S, Vukojević K, Gugić Bokun D, Vlak T Tags: Wien Klin Wochenschr Source Type: research

Rheumatological care in rural areas : The Rheuma-Bus project 2018.
CONCLUSION: The findings showed that there is still a lot of negligence in awareness and knowledge of rheumatic diseases, at least in rural areas. PMID: 32189120 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - March 18, 2020 Category: General Medicine Authors: Puchner R, Schaffer G, Sautner J, Alkin A, Machold K, Stamm T Tags: Wien Klin Wochenschr Source Type: research

Health-enhancing physical activity, exercise and sports-a  never-ending success story.
Health-enhancing physical activity, exercise and sports-a never-ending success story. Wien Klin Wochenschr. 2020 Mar 16;: Authors: Crevenna R PMID: 32179990 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - March 16, 2020 Category: General Medicine Authors: Crevenna R Tags: Wien Klin Wochenschr Source Type: research

Comparisons of venous indwelling needles and intravenous infusion with steel needles in pediatric outpatient care.
Abstract OBJECTIVE: To compare the application effects of venous indwelling needles and intravenous infusion with steel needles in pediatric outpatient care and to observe the complications of the two approaches. METHODS: A total of 110 children who received intravenous infusions in our hospital from March 2018 to May 2018 were selected as study subjects. Children were assigned to an observation group (n = 55) or a control group (n = 55) based on a random number table, of which the children in the control group received intravenous infusion with the steel needles while the children...
Source: Wiener Klinische Wochenschrift - March 9, 2020 Category: General Medicine Authors: Sun L, Yang Y Tags: Wien Klin Wochenschr Source Type: research

Against all odds-the persistent popularity of homeopathy.
Abstract The use of homeopathy is remarkably popular. Popularity, however, is not an arbiter in a scientific discourse. In fact, the assumptions underlying homeopathy violate fundamental laws of nature. Homeopathy does not have any explanatory power and fails other criteria established for a scientific approach. Two large-scale efforts have recently documented that in spite of a plethora of clinical trials there is no evidence that homeopathic remedies have any therapeutic effect, which goes beyond that of a placebo. Relaxed regulations and lack of scientific literacy and of health education al...
Source: Wiener Klinische Wochenschrift - March 9, 2020 Category: General Medicine Authors: Cukaci C, Freissmuth M, Mann C, Marti J, Sperl V Tags: Wien Klin Wochenschr Source Type: research

Self-assessment of medical students and young physicians in training : Self-confidence of clinical competencies and working or learning environment.
CONCLUSIONS: Self-confidence of young physicians but also their stress levels increased during the medical training. Further studies are needed to answer the question why the interest in family medicine was so unexpectedly low in this cohort. PMID: 32130522 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - March 4, 2020 Category: General Medicine Authors: Lambert T, Blessberger H, Fellner A, Steinwender C, Tekian A Tags: Wien Klin Wochenschr Source Type: research

Trends in incidence of anal cancer in Austria, 1983-2016.
Abstract BACKGROUND: Recent reports have noted increasing rates of anal cancer among high-income countries worldwide; however, little is known about these trends in Austria. METHODS: Data on anal cancer from 1983 to 2016 were obtained from Statistics Austria. All tumors (n = 3567) were classified into anal squamous cell carcinomas (ASCC), anal adenocarcinomas (AADC), and others (unspecified carcinoma and other specific carcinoma). Anal cancer incidence rates were calculated in 5‑year cycles and incidence average annual percentage change (AAPC) to evaluate trends by sex, histology and age group. ...
Source: Wiener Klinische Wochenschrift - March 4, 2020 Category: General Medicine Authors: Heer E, Hackl M, Ferlitsch M, Waldhoer T, Yang L Tags: Wien Klin Wochenschr Source Type: research

[Cardiogenic shock].
Abstract Cardiogenic shock (CS) is defined as end-organ hypoperfusion as the consequence of primary myocardial dysfunction. Among the diagnostic criteria are a systolic blood pressure
Source: Wiener Klinische Wochenschrift - February 24, 2020 Category: General Medicine Authors: Zilberszac R, Heinz G Tags: Wien Klin Wochenschr Source Type: research

Heart failure disease management programs in Austria 2019 : A  systematic survey of the Heart Failure Working Group and the Working Group for Cardiological Assistance and Care Personnel of the Austrian Society of Cardiology.
Heart failure disease management programs in Austria 2019 : A systematic survey of the Heart Failure Working Group and the Working Group for Cardiological Assistance and Care Personnel of the Austrian Society of Cardiology. Wien Klin Wochenschr. 2020 Feb 18;: Authors: Poelzl G, Fetz B, Altenberger J, Fritsch M, Auer J, Stachl E, Boehmer A, Frauendorfer H, Ebner C, Geyrhofer F, Pötz S, Prim A, Alber H, de Grandis R, Drack C, Hülsmann M, Heart Failure Working Group and the Working Group for Cardiological Assistance and Care Personnel of the Austrian Society for Cardiology Abstract Heart f...
Source: Wiener Klinische Wochenschrift - February 18, 2020 Category: General Medicine Authors: Poelzl G, Fetz B, Altenberger J, Fritsch M, Auer J, Stachl E, Boehmer A, Frauendorfer H, Ebner C, Geyrhofer F, Pötz S, Prim A, Alber H, de Grandis R, Drack C, Hülsmann M, Heart Failure Working Group and the Working Group for Cardiological Assistance and Tags: Wien Klin Wochenschr Source Type: research

Presepsin:albumin ratio and C-reactive protein:albumin ratio as novel sepsis-based prognostic scores : A  retrospective study.
Presepsin:albumin ratio and C-reactive protein:albumin ratio as novel sepsis-based prognostic scores : A retrospective study. Wien Klin Wochenschr. 2020 Feb 14;: Authors: Kaplan M, Duzenli T, Tanoglu A, Cakir Guney B, Onal Tastan Y, Bicer HS Abstract OBJECTIVE: To investigate the prognostic value of the presepsin:albumin ratio and C‑reactive protein:albumin ratio in patients with sepsis in the intensive care unit (ICU). METHODS: A total of 228 (129 males and 99 females) patients with newly diagnosed sepsis were included in the study. The relationship between the C‑reactive protein:a...
Source: Wiener Klinische Wochenschrift - February 14, 2020 Category: General Medicine Authors: Kaplan M, Duzenli T, Tanoglu A, Cakir Guney B, Onal Tastan Y, Bicer HS Tags: Wien Klin Wochenschr Source Type: research

Prescription of individual therapeutic exercises via smartphone app for patients suffering from non-specific back pain : A  qualitative feasibility and quantitative pilot study.
CONCLUSION: The prescription of therapeutic exercises via smartphone app to patients suffering from non-specific back pain is feasible and well-accepted in patients at all ages. Pilot data additionally pointed towards efficacy of the intervention. PMID: 32060724 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - February 14, 2020 Category: General Medicine Authors: Hasenöhrl T, Windschnurer T, Dorotka R, Ambrozy C, Crevenna R Tags: Wien Klin Wochenschr Source Type: research

Partial oral antibiotic therapy is non-inferior to intravenous therapy in non-critically ill patients with infective endocarditis : Review and meta-analysis.
CONCLUSION: Data comparing POT with standard care in IE is limited and to date only one sufficiently powered stand-alone trial exists to support its use. In this meta-analysis POT was non-inferior to i.v. therapy with respect to mortality and IE relapse in non-critically ill patients suffering from both left-sided and right-sided IE. These findings indicate that POT is a feasible treatment strategy in selected patients suffering from IE but further validation in future studies will be required. PMID: 32040621 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - February 10, 2020 Category: General Medicine Authors: Rezar R, Jirak P, Lichtenauer M, Jung C, Lauten A, Hoppe UC, Wernly B Tags: Wien Klin Wochenschr Source Type: research