Clinical pharmacist interventions in cardiovascular disease pharmacotherapy in elderly patients on excessive polypharmacy : A  retrospective pre-post observational multicentric study.
In this study 243 patients were included and 980 interventions were proposed in the MR form of which 479 (48.9%) were accepted by the general practitioners (GP). The CPs proposed 320 interventions in CVDs treatment, of which 140 were accepted by the GPs (43.8%). The acceptance of the CPs' recommendations reduced the number of medications by 7.3% (from 13.1 to 12.1 per patient; p 
Source: Wiener Klinische Wochenschrift - January 20, 2021 Category: General Medicine Authors: Stuhec M, Flegar I, Zelko E, Kovačič A, Zabavnik V Tags: Wien Klin Wochenschr Source Type: research

Higher serum uric acid is associated with higher risks of thrombosis and death in patients with primary myelofibrosis.
Abstract BACKGROUND: Serum uric acid (SUA) can promote inflammation and is associated with increased cardiovascular morbidity. Primary (PMF) and secondary myelofibrosis (SMF) are myeloproliferative neoplasms characterized by high cellular turnover and substantial risk of thrombosis and death. METHODS: We have retrospectively investigated SUA in 173 patients with myelofibrosis (125 PMF; 48 SMF) and 30 controls. RESULTS: The PMF patients had significantly higher SUA in comparison to SMF and controls. In both PMF and SMF higher SUA was significantly associated with arterial hypertension and d...
Source: Wiener Klinische Wochenschrift - January 19, 2021 Category: General Medicine Authors: Lucijanic M, Krecak I, Galusic D, Sedinic M, Holik H, Perisa V, Moric Peric M, Zekanovic I, Stoos-Veic T, Pejsa V, Kusec R Tags: Wien Klin Wochenschr Source Type: research

A  clinical retrospective study of percutaneous dilatational tracheostomy without guide wire for critically ill patients.
CONCLUSION: Overall, NGPDT with controlled steps is a fast, safe, and microinvasive procedure. It mildly stimulates the trachea with a low rate of complications. PMID: 33427936 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - January 11, 2021 Category: General Medicine Authors: Du XY, Zhai XD, Liu Z Tags: Wien Klin Wochenschr Source Type: research

Septoplasties are unlikely to cause postoperative numbness of the anterior palate.
CONCLUSION: At this current time, this is the largest study investigating postoperative numbness of the anterior palate retracing septoplasty or septorhinoplasty. As a result, the currently used techniques for the operations do not pose a risk for the incisive nerve despite close surgical manipulation to the nerves' course. Nevertheless, patients should be informed and educated about the possibility of an occurring sensitivity disorder regarding the anterior palate during informed consent. PMID: 33420811 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - January 9, 2021 Category: General Medicine Authors: Andrianakis A, Bachlechner M, Kainz J, Herber V, Payer M, Tomazic PV Tags: Wien Klin Wochenschr Source Type: research

Clinical-Pathological Conference Series from the Medical University of Graz : Case No  173: A 77-year-old patient with adenocarcinoma of the prostate, liver metastases and watery diarrhea.
Clinical-Pathological Conference Series from the Medical University of Graz : Case No 173: A 77-year-old patient with adenocarcinoma of the prostate, liver metastases and watery diarrhea. Wien Klin Wochenschr. 2021 Jan 04;: Authors: Fabian E, Kump P, Schiller D, Brcic I, Gruber C, Heitz PU, Klöppel G, Lipp RW, Moinfar F, Schöfl R, Fickert P, Krejs GJ PMID: 33398457 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - January 4, 2021 Category: General Medicine Authors: Fabian E, Kump P, Schiller D, Brcic I, Gruber C, Heitz PU, Klöppel G, Lipp RW, Moinfar F, Schöfl R, Fickert P, Krejs GJ Tags: Wien Klin Wochenschr Source Type: research

Development of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches M édicales de Lambaréné (CERMEL), Gabon.
Development of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon. Wien Klin Wochenschr. 2021 Jan 04;: Authors: Ramharter M, Agnandji ST, Adegnika AA, Lell B, Mombo-Ngoma G, Grobusch MP, McCall M, Muranaka R, Kreidenweiss A, Velavan TP, Esen M, Schaumburg F, Alabi A, Druml C, Mordmüller B, Köhler C, Kremsner PG Abstract Medical research in sub-Saharan Africa is of high priority for societies to respond adequately to local health needs. Often enough it remains a challenge to bu...
Source: Wiener Klinische Wochenschrift - January 4, 2021 Category: General Medicine Authors: Ramharter M, Agnandji ST, Adegnika AA, Lell B, Mombo-Ngoma G, Grobusch MP, McCall M, Muranaka R, Kreidenweiss A, Velavan TP, Esen M, Schaumburg F, Alabi A, Druml C, Mordmüller B, Köhler C, Kremsner PG Tags: Wien Klin Wochenschr Source Type: research

Relationship between serum osteopontin levels and the severity of COVID-19 infection.
This study included 84 patients, 43 female and 45 male. Patients were divided into 2 groups, group 1 non-severe group (n: 48), group 2 severe (n: 40). Demographic data, neutrophil, lymphocyte, platelet, white blood cell counts, albumin, procalcitonin, C‑reactive protein (CRP) and OPN levels were recorded. The OPN levels and these inflammatory parameters of the two groups were compared. RESULTS: There were no significant differences in terms of gender (female/male 25/23 vs. 18/22) and platelet count (178 K/μL vs. 191 K/μL) between the groups (p > 0.05). Ages (57.7...
Source: Wiener Klinische Wochenschrift - December 28, 2020 Category: General Medicine Authors: Varım C, Demirci T, Cengiz H, Hacıbekiroğlu İ, Tuncer FB, Çokluk E, Toptan H, Karabay O, Yıldırım İ Tags: Wien Klin Wochenschr Source Type: research

Direct patient-physician communication via a  hepatitis C hotline facilitates treatment initiation in patients with poor adherence.
CONCLUSION: The implementation of a physician-operated phone hotline for patients with HCV infection facilitated treatment initiation in an HCV population with poor adherence. Mainly due to losses to follow-up, the SVR rate remained suboptimal with 70%. PMID: 33351152 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 22, 2020 Category: General Medicine Authors: Steininger L, Chromy D, Bauer D, Simbrunner B, Binter T, Schwabl P, Schmidbauer C, Trauner M, Gschwantler M, Mandorfer M, Reiberger T Tags: Wien Klin Wochenschr Source Type: research

Effectiveness of focused extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome : A  randomized, placebo-controlled pilot study.
CONCLUSION: Focused extracorporeal shock wave therapy is an effective and noninvasive treatment method for mild to moderate carpal tunnel syndrome. PMID: 33351153 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 22, 2020 Category: General Medicine Authors: Gesslbauer C, Mickel M, Schuhfried O, Huber D, Keilani M, Crevenna R Tags: Wien Klin Wochenschr Source Type: research

Incidental findings of clinical relevance.
PMID: 33351154 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 22, 2020 Category: General Medicine Authors: Trabauer BM, Szag K, Krampla W Tags: Wien Klin Wochenschr Source Type: research

Sex and age differences in COVID-19 mortality in Europe.
CONCLUSION: Despite variability in data collection and time coverage among regions, the study showed an overall similar pattern of sex differences in COVID-19 mortality in Europe. PMID: 33351155 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 22, 2020 Category: General Medicine Authors: Ahrenfeldt LJ, Otavova M, Christensen K, Lindahl-Jacobsen R Tags: Wien Klin Wochenschr Source Type: research

Establishing a  telerehabilitation program for patients with Duchenne muscular dystrophy in the COVID-19 pandemic.
CONCLUSION: With the physiotherapist guidance (online communication or video) patients with caregivers' help can continue home based rehabilitation. Online videos/instructions/video guidelines are more acceptable by parents/caregivers of patients with Duchenne muscular dystrophy than live workshops. PMID: 33346889 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 21, 2020 Category: General Medicine Authors: Sobierajska-Rek A, Mański Ł, Jabłońska-Brudło J, Śledzińska K, Ucińska A, Wierzba J Tags: Wien Klin Wochenschr Source Type: research

Prevalence of neuropathy in patients with type 2 diabetes in Iran : A  systematic review and meta-analysis.
This study attempts to determine the overall prevalence of neuropathy in patients with type 2 diabetes in Iran with a meta-analysis. METHODS: The present study was conducted using a meta-analysis method from January 2000 to December 2018. The papers related to the study subject were obtained from searching Scopus, ScienceDirect, Magiran, Barakat Knowledge Network, SID, Medline (PubMed), and Google Scholar databases. The heterogeneity of studies was examined using I2 index and the data were analyzed using the software Comprehensive Meta-Analysis (version 3, Biostat, Englewood, NJ, USA). RE...
Source: Wiener Klinische Wochenschrift - December 17, 2020 Category: General Medicine Authors: Aliabadi DA, Moradian N, Rahmanian E, Mohammadi M Tags: Wien Klin Wochenschr Source Type: research

Integrating public health policies in the epidemiological modeling of hepatitis  C with LEHC tool: application in Austria.
CONCLUSION: In Austria, the LEHC tool allowed to forecast the HCV elimination year anticipation to 2026, instead of being achieved after 2030. This target will only be valid if adequate management of the 24 public health policies focused on this pathology is further implemented. PMID: 33331968 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 17, 2020 Category: General Medicine Authors: Lopes H, Baptista-Leite R, Franco D, Pirker R, Gschwantler M Tags: Wien Klin Wochenschr Source Type: research

Immunotherapy and vaccination against infectious diseases.
This article provides a brief overview of recent advances in immunomodulatory therapy and other strategies in the treatment of infectious disease. PMID: 33326055 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 16, 2020 Category: General Medicine Authors: Ebbers M, Hemmer CJ, Müller-Hilke B, Reisinger EC Tags: Wien Klin Wochenschr Source Type: research

Towards understanding vaccine hesitancy and vaccination refusal in Austria.
Abstract In Austria, data on vaccine hesitancy is scarce. Available studies suggest around 1-11% of parents refuse vaccination, while many more are hesitant and consider refraining from some but not all of the recommended vaccinations. However, the key drivers for vaccine hesitancy in Austria are largely unknown. To learn more about vaccination coverage, attitude towards and knowledge around immunization as well as views on mandatory vaccination, we conducted a survey in a rural Austrian lay population including adults and children. Two paper-based questionnaires, one for adults 16 years or older and one for child...
Source: Wiener Klinische Wochenschrift - December 11, 2020 Category: General Medicine Authors: Bauer A, Tiefengraber D, Wiedermann U Tags: Wien Klin Wochenschr Source Type: research

Personal protective equipment in the COVID-19 pandemic and the use of cooling-wear as alleviator of thermal stress : A  pilot study in plastic surgery staff members.
CONCLUSION: COVID-19 PPE causes considerable thermal stress, ultimately affecting human performance. As opportunity to withstand thermal stress, and improve patients' and professionals' safety, cooling-wear can be considered relevant. Medical personnel performing in exceptional situations may particularly benefit from further development and investigation of cooling strategies. PMID: 33301061 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 10, 2020 Category: General Medicine Authors: Luze H, Nischwitz SP, Kotzbeck P, Fink J, Holzer JCJ, Popp D, Kamolz LP Tags: Wien Klin Wochenschr Source Type: research

What sports activity levels are achieved in long-term survivors with modular endoprosthetic humerus reconstruction following primary bone sarcoma resection?
Abstract BACKGROUND: The aim of the study was to assess (1) sports activity, (2) sports involving the upper extremities, (3) functional outcome and (4) sports-related complications of long-term survivors of primary malignant bone tumors of the proximal humerus. METHODS: A total of 18 patients with an endoprosthetic reconstruction for primary malignant bone sarcoma of the proximal humerus (8 male, 10 female, mean age 19.9 ± 8.4 years, range 7.8-37.4 years) with an average follow-up of 18.1 ± 7.4 years (range 6.7-29.8 years) were included. The t...
Source: Wiener Klinische Wochenschrift - December 9, 2020 Category: General Medicine Authors: Lang NW, Kasparek MF, Synak L, Waldstein W, Funovics PT, Windhager R, Hobusch GM Tags: Wien Klin Wochenschr Source Type: research

Molecularly guided treatment of metastatic parotid gland carcinoma in adults.
CONCLUSION: A total of eight therapy recommendations were provided. Based on our observations, molecular-guided therapies may be a feasible treatment approach for this rare disease entity. PMID: 33296026 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 9, 2020 Category: General Medicine Authors: Taghizadeh H, Müllauer L, Mader RM, Füreder T, Prager GW Tags: Wien Klin Wochenschr Source Type: research

Effect of early oseltamivir on outpatients without hypoxia with suspected COVID-19.
Abstract BACKGROUND: Since December 2019 coronavirus disease 2019 (COVID-19) outbreaks have occurred in China and many countries around the world. The effectiveness of oseltamivir on COVID-19 suspected outpatients without hypoxia was evaluated. METHODS: A total of 16 COVID-19 suspected medical personnel and their cohabitation families without hypoxia, who came to the adult fever clinic from March to June 2020 were studied. All patients received antiviral therapy (oseltamivir) and antibacterial therapy together. RESULTS: Most of the infected patients were female (10, 63%), 1 had diabetes (6%) and 3 h...
Source: Wiener Klinische Wochenschrift - December 9, 2020 Category: General Medicine Authors: Chiba S Tags: Wien Klin Wochenschr Source Type: research

Effect of music on patients with cardiovascular diseases and during cardiovascular interventions : A  systematic review.
CONCLUSION: Currently no definite effect of receptive music intervention on the cardiovascular system can be verified. Further research is needed to assess music as an inexpensive and easy applicable form of therapy. PMID: 33296028 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 9, 2020 Category: General Medicine Authors: Ho CY, Wexberg P, Schneider B, Stöllberger C Tags: Wien Klin Wochenschr Source Type: research

Sociodemographic predictors of pain in old people : Serbian population-based study.
CONCLUSION: Pain is less likely in people of age below 85 years, male gender, those with higher educational level and higher wealth index, as well as overweight or obese individuals. Also, we have demonstrated that sociodemographic predictors differently correlate with the onset of the pain and its severity degree in persons of 65 years and older. PMID: 33296029 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 9, 2020 Category: General Medicine Authors: Santric Milicevic M, Nikolic D, Kostadinovic M, Babic U, Mitrovic-Jovanovic M, Milanovic F, Bavec A Tags: Wien Klin Wochenschr Source Type: research

COVID-19: IgG seroconversion under intensive glucocorticoid treatment in a  high-risk patient with minimal change disease.
COVID-19: IgG seroconversion under intensive glucocorticoid treatment in a high-risk patient with minimal change disease. Wien Klin Wochenschr. 2020 Dec 08;: Authors: Eder M, Strassl R, Kläger J, Aigner C, Thalhammer F, Kikić Ž Abstract In this case report we present a rare case of a patient with multiple risk factors for severe coronavirus disease (COVID 19) in whom intensive glucocorticoid treatment due to incipient nephrotic syndrome coincided with SARS-CoV‑2 infection. Despite this high baseline risk profile and the use of glucocorticoids the patient developed only mil...
Source: Wiener Klinische Wochenschrift - December 8, 2020 Category: General Medicine Authors: Eder M, Strassl R, Kläger J, Aigner C, Thalhammer F, Kikić Ž Tags: Wien Klin Wochenschr Source Type: research

Association of digoxin therapy with case fatality rate in acute pulmonary embolism.
CONCLUSION: Digoxin has been used extensively for decades in the treatment of heart failure and arrhythmias despite some controversies over its benefit. For the first time in the literature, we have demonstrated independent association of digoxin therapy with short-term and long-term mortality in patients with acute pulmonary embolism. PMID: 33289855 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 8, 2020 Category: General Medicine Authors: Karataş MB, Yelgeç NS, Çanga Y, Zengin A, Emre A Tags: Wien Klin Wochenschr Source Type: research

Preauricular sinus.
PMID: 33275181 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 4, 2020 Category: General Medicine Authors: Bakshi SS, Ramesh S Tags: Wien Klin Wochenschr Source Type: research

Diagnosis and treatment of cardiac amyloidosis: an interdisciplinary consensus statement.
yen N, Weber T, Zaruba MM, Badr Eslam R, Hülsmann M, Mascherbauer J Abstract The prevalence and significance of cardiac amyloidosis have been considerably underestimated in the past; however, the number of patients diagnosed with cardiac amyloidosis has increased significantly recently due to growing awareness of the disease, improved diagnostic capabilities and demographic trends. Specific therapies that improve patient prognosis have become available for certain types of cardiac amyloidosis. Thus, the earliest possible referral of patients with suspicion of cardiac amyloidosis to an experienced center is cr...
Source: Wiener Klinische Wochenschrift - December 3, 2020 Category: General Medicine Authors: Bonderman D, Pölzl G, Ablasser K, Agis H, Aschauer S, Auer-Grumbach M, Binder C, Dörler J, Duca F, Ebner C, Hacker M, Kain R, Kammerlander A, Koschutnik M, Kroiss AS, Mayr A, Nitsche C, Rainer PP, Reiter-Malmqvist S, Schneider M, Schwarz R, Verheyen N, Tags: Wien Klin Wochenschr Source Type: research

Perceptions on the management of varices and on the use of albumin in patients with cirrhosis among GI specialists in Austria.
CONCLUSION: The reported management of PH and varices is mostly adherent to guidelines, but endoscopic surveillance in patients without varices is too intense and EBL is overused in the setting of PP. Knowledge on the correct use of early TIPS must be improved among Austrian specialists. Albumin use is widely unrestricted in Austria; however, albumin is often underdosed in established indications. PMID: 33270161 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - December 3, 2020 Category: General Medicine Authors: Pfisterer N, Schmidbauer C, Riedl F, Maieron A, Stadlbauer V, Hennlich B, Schwarzer R, Puespoek A, Bucsics T, Effenberger M, Bota S, Gschwantler M, Peck-Radosavljevic M, Mandorfer M, Madl C, Trauner M, Reiberger T Tags: Wien Klin Wochenschr Source Type: research

A  little is better than none: the biggest gain of physical activity in patients with ischemic heart disease.
A little is better than none: the biggest gain of physical activity in patients with ischemic heart disease. Wien Klin Wochenschr. 2020 Dec 01;: Authors: Huber A, Höfer S, Saner H, Oldridge N Abstract BACKGROUND: There is a relationship between physical activity and health-related quality of life (HRQL) in healthy people and in patients with ischemic heart disease (IHD). The purpose of this study was to determine whether this relationship between sports or recreational physical activity levels and HRQL has a dose-response gradient in patients with IHD. METHODS: Using one generic and thr...
Source: Wiener Klinische Wochenschrift - December 1, 2020 Category: General Medicine Authors: Huber A, Höfer S, Saner H, Oldridge N Tags: Wien Klin Wochenschr Source Type: research

Recommendations on the utilization of telemedicine in cardiology.
f the Austrian Cardiological Society Abstract The enormous progress made in recent years in the field of information and communication technology and also in sensor and computer technology has affected numerous fields of medicine and is capable of inducing even radical changes in diagnostic and therapeutic processes. This is particularly true for cardiology, where, for example, telemetric monitoring of cardiac and circulatory functions has been in use for many years. Nevertheless, broad application of newer telemedical processes has not yet been achieved to the extent one would expect from the encouraging results ...
Source: Wiener Klinische Wochenschrift - December 1, 2020 Category: General Medicine Authors: Gruska M, Aigner G, Altenberger J, Burkart-Küttner D, Fiedler L, Gwechenberger M, Lercher P, Martinek M, Nürnberg M, Pölzl G, Porenta G, Sauermann S, Schukro C, Scherr D, Steinwender C, Stühlinger M, Teubl A, Working Group Rhythmology of the Austrian Tags: Wien Klin Wochenschr Source Type: research

Diagnosis of hepatic nuclear factor  1A monogenic diabetes mellitus (HNF1A-MODY) impacts antihyperglycemic treatment.
We describe two adult patients with monogenic diabetes, both identified as HNF1A-MODY, genetically c.815G>A, p.Arg272His and c675delC, p.Ser225Argfs*8, respectively. They were misdiagnosed as having type 1 diabetes mellitus, and consequently, initiating insulin therapy led to hypoglycemia and unstable blood glucose control. Usually, sulfonylureas represent the basis of antidiabetic treatment in patients with HNF1A-MODY; however, all medical personnel involved in diabetes care should be aware of monogenic diabetes mellitus and the possibilities for genetic testing. The patients observed have shown the necessity of t...
Source: Wiener Klinische Wochenschrift - November 27, 2020 Category: General Medicine Authors: Schnedl WJ, Holasek SJ, Schenk M, Enko D, Mangge H Tags: Wien Klin Wochenschr Source Type: research

Clinical manifestations of COVID-19 in the general population: systematic review.
This study aimed to systematize the literature regarding clinical manifestations of patients with confirmed COVID-19. A systematic review of the literature was conducted. A total of 8070 scientific productions were found in the databases. Among the studies, 184 met the initial inclusion criteria, with a total of 114,046 patients. After complete reading, 32 studies that did not report clinical manifestations were excluded. The 152 publications finally included a total of 41,409 individuals from at least 23 countries and 26 different clinical manifestations were reported. In percentage term...
Source: Wiener Klinische Wochenschrift - November 26, 2020 Category: General Medicine Authors: da Rosa Mesquita R, Francelino Silva Junior LC, Santos Santana FM, Farias de Oliveira T, Campos Alcântara R, Monteiro Arnozo G, Rodrigues da Silva Filho E, Galdino Dos Santos AG, Oliveira da Cunha EJ, Salgueiro de Aquino SH, Freire de Souza CD Tags: Wien Klin Wochenschr Source Type: research

[Diagnosis, prevention and therapy of lymphedema].
KF PMID: 33226525 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - November 23, 2020 Category: General Medicine Authors: Flores T, Bergmeister KD, Staudenherz A, Pieber K, Schrögendorfer KF Tags: Wien Klin Wochenschr Source Type: research

A  retrospective comparison between influenza and COVID-19-associated ARDS in a Croatian tertiary care center.
CONCLUSION: High mortality of IMV patients with influenza and COVID 19 with 55% and 63%, respectively, challenges and urges medical and especially ICU community to expand our quest for further treatments, especially since ECMO use that is scarcely required in COVID 19 patients probably has limited impact in reducing mortality in COVID 19 patients. PMID: 33216213 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - November 20, 2020 Category: General Medicine Authors: Gjurašin B, Santini M, Krajinović V, Papić N, Atelj A, Kotarski V, Krznarić J, Vargović M, Kutleša M Tags: Wien Klin Wochenschr Source Type: research

Austrian recommendations for the management of essential thrombocythemia.
r H Abstract According to the World Health Organization (WHO) classification, essential (primary) thrombocythemia (ET) is one of several Bcr-Abl negative chronic myeloproliferative neoplasms (MPN). The classical term MPN covers the subcategories of MPN: ET, polycythemia vera (PV), primary myelofibrosis (PMF), and prefibrotic PMF (pPMF). ET is marked by clonal proliferation of hematopoietic stem cells, leading to a chronic overproduction of platelets. At the molecular level a JAK2 (Janus Kinase 2), calreticulin, or MPL mutation is found in the majority of patients. Typical ongoing complications of the dis...
Source: Wiener Klinische Wochenschrift - November 19, 2020 Category: General Medicine Authors: Buxhofer-Ausch V, Heibl S, Sliwa T, Beham-Schmid C, Wolf D, Geissler K, Krauth MT, Krippl P, Petzer A, Wölfler A, Melchardt T, Gisslinger H Tags: Wien Klin Wochenschr Source Type: research

The positive effect of spermidine in older adults suffering from dementia : First results of a  3-month trial.
The positive effect of spermidine in older adults suffering from dementia : First results of a 3-month trial. Wien Klin Wochenschr. 2020 Nov 19;: Authors: Pekar T, Bruckner K, Pauschenwein-Frantsich S, Gschaider A, Oppliger M, Willesberger J, Ungersbäck P, Wendzel A, Kremer A, Flak W, Wantke F, Jarisch R Abstract The worldwide prevalence of dementia is estimated at 35.6 million and will rise to 115 million by 2050. There is therefore an urgent need for well-founded dementia diagnostics and well-researched therapeutic options. Previous studies have highlighted that spermidine has th...
Source: Wiener Klinische Wochenschrift - November 19, 2020 Category: General Medicine Authors: Pekar T, Bruckner K, Pauschenwein-Frantsich S, Gschaider A, Oppliger M, Willesberger J, Ungersbäck P, Wendzel A, Kremer A, Flak W, Wantke F, Jarisch R Tags: Wien Klin Wochenschr Source Type: research

Structured ICU resource management in a  pandemic is associated with favorable outcome in critically ill COVID‑19 patients.
CONCLUSION: Critically ill COVID-19 patients in Tyrol showed high severity of disease often requiring complex treatment with increased lengths of ICU and hospital stay. Nevertheless, the mortality was found to be remarkably low, which may be attributed to our adaptive surge response providing sufficient ICU resources. PMID: 33170333 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - November 10, 2020 Category: General Medicine Authors: Klein SJ, Bellmann R, Dejaco H, Eschertzhuber S, Fries D, Furtwängler W, Gasteiger L, Hasibeder W, Helbok R, Hochhold C, Hofer S, Kirchmair L, Krismer C, Ladner E, Lehner GF, Mathis S, Mayr A, Mittermayr M, Peer A, Preuß Hernández C, Reitter B, Ströhl Tags: Wien Klin Wochenschr Source Type: research

Treatment of partial thickness burns of the face with Acticoat7 ™ : A retrospective single center study.
CONCLUSION: Acticoat7™ is a valuable dressing for treating superficial and deep partial thickness burn wounds of the face in an intensive care unit setting. It enables extended time intervals between dressing changes without an increased risk for complications. PMID: 33128100 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 30, 2020 Category: General Medicine Authors: Nedomansky J, Oramary A, Nickl S, Fuchs G, Radtke C, Haslik W, Fochtmann-Frana A Tags: Wien Klin Wochenschr Source Type: research

Impact of COVID-19 on Christmas.
PMID: 33125579 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 30, 2020 Category: General Medicine Authors: Wormser GP Tags: Wien Klin Wochenschr Source Type: research

Profile of SARS-CoV-2.
Abstract The recent emergence of a new coronavirus (severe acute respiratory syndrome coronavirus‑2, SARS-CoV-2) that is transmitted efficiently among humans and can result in serious disease and/or death has become a global threat to public health and economy. In this article, we describe some of the most important characteristics of this new virus (including gaps in our understanding) and provide a perspective of ongoing activities for developing virus-specific countermeasures, such as vaccines and antiviral drugs. PMID: 33125580 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 30, 2020 Category: General Medicine Authors: Heinz FX, Stiasny K Tags: Wien Klin Wochenschr Source Type: research

Clinical-Pathological Conference Series from the Medical University of Graz : Case No  170: A 33-year-old psychologist with severe dyspnea and right-sided chylothorax.
Clinical-Pathological Conference Series from the Medical University of Graz : Case No 170: A 33-year-old psychologist with severe dyspnea and right-sided chylothorax. Wien Klin Wochenschr. 2020 Oct 29;: Authors: Bauer PK, Flicker M, Fabian E, Flick H, Brcic L, Liegl-Atzwanger B, Janisch M, Fuchsjäger M, Olschewski H, Krejs GJ PMID: 33119872 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 29, 2020 Category: General Medicine Authors: Bauer PK, Flicker M, Fabian E, Flick H, Brcic L, Liegl-Atzwanger B, Janisch M, Fuchsjäger M, Olschewski H, Krejs GJ Tags: Wien Klin Wochenschr Source Type: research

Individual cognitive changes in subjective cognitive decline, mild cognitive impairment and Alzheimer's disease using the reliable change index methodology.
CONCLUSION: The results reflect the cognitive deterioration of patients during the disease progression. Nevertheless, improvements in diagnostic groups could be detected. The significantly positive changes might be due to practice effects, also a lack of motivation or attention in the first test could have yielded "improvement" in the retest. PMID: 33095320 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 23, 2020 Category: General Medicine Authors: Rosas AG, Stögmann E, Lehrner J Tags: Wien Klin Wochenschr Source Type: research

Covid-19 screening: are forehead temperature measurements during cold outdoor temperatures really helpful?
CONCLUSION: Our results indicate that forehead infrared temperature control is not an appropriate tool to screen for infectious disease directly at the entrance of a building, at least during early spring season with cold outdoor temperatures. PMID: 33095321 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 23, 2020 Category: General Medicine Authors: Dzien C, Halder W, Winner H, Lechleitner M Tags: Wien Klin Wochenschr Source Type: research

Considering additive effects of polypharmacy : Analysis of adverse events in geriatric patients in long-term care facilities.
CONCLUSION: Patients in long-term facilities frequently suffer from many adverse events. Concomitantly administered drugs have to be frequently considered as plausible causes for adverse events. These additive effects of drugs should be more focused in patient care and research. PMID: 33090261 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 22, 2020 Category: General Medicine Authors: Lexow M, Wernecke K, Schmid GL, Sultzer R, Bertsche T, Schiek S Tags: Wien Klin Wochenschr Source Type: research

Long-term impact of olfactory dysfunction on daily life.
CONCLUSION: Despite negative effects of OD on certain activities in daily life, such as cooking, detecting spoiled food, or personal hygiene, it seems that the patients included in this study adapted to the OD in the long-term. The current findings should aid clinicians in patient counselling. PMID: 33084955 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 21, 2020 Category: General Medicine Authors: Auinger AB, Besser G, Liu DT, Renner B, Mueller CA Tags: Wien Klin Wochenschr Source Type: research

Fatal case of COVID-19 in a  27-year-old woman with diabetes mellitus.
Fatal case of COVID-19 in a 27-year-old woman with diabetes mellitus. Wien Klin Wochenschr. 2020 Oct 07;: Authors: Schlömmer C, Dünser MW, Antlanger M, Paar C, Winkler M, Meier J, Lamprecht B, Salzer HJF PMID: 33026521 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - October 6, 2020 Category: General Medicine Authors: Schlömmer C, Dünser MW, Antlanger M, Paar C, Winkler M, Meier J, Lamprecht B, Salzer HJF Tags: Wien Klin Wochenschr Source Type: research

Utility of procalcitonin in a  medical intensive care unit in Croatia.
In this study 129 patients of median age 64 years (interquartile range 39-89 years) were prospectively included. The Acute Physiology And Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA) scores were 21 ± 14 and 7 ± 6, respectively. Intensive care unit (ICU) mortality was 22.5%. Immunocompromised patients constituted 39.5%. A significant correlation was observed between PCT and APACHE II (Spearman's rho 0.461, p 
Source: Wiener Klinische Wochenschrift - October 5, 2020 Category: General Medicine Authors: Vujaklija Brajković A, Košuta I, Tomek D, Rora M, Babel J, Rogić D, Lončar Vrančić A, Radonić R Tags: Wien Klin Wochenschr Source Type: research

Association between psoriasis, psoriatic arthritis and gastrointestinal disease : An exploratory nationwide inpatient sample analysis.
Abstract BACKGROUND: Psoriasis is associated with cardiovascular disease, inflammatory bowel disease (IBD), metabolic syndrome, and psychiatric disease. Furthermore, psoriasis is associated with immune dysregulation and systemic inflammation. OBJECTIVE: To determine the association of psoriasis and psoriatic arthritis with IBD and the association of the combination of psoriasis or psoriatic arthritis with IBD and other gastrointestinal illnesses. METHODS: Discharge data from the 2000-2014 Nationwide Inpatient Sample, Healthcare Cost and Utilization Project (HCUP), which approximates a 20% stratified...
Source: Wiener Klinische Wochenschrift - September 22, 2020 Category: General Medicine Authors: Yousaf A, Raiker R, Davis SM, Gayam S, Zinn Z Tags: Wien Klin Wochenschr Source Type: research

Effects of a  structured exercise program on physical performance and function, quality of life and work ability of physically active breast cancer survivors : A retrospective data analysis.
CONCLUSION: A structured and well-planned exercise intervention program can have a large effect on the physical performance of pretrained breast cancer survivors. Moreover, it can increase the body image and decrease the arm symptoms in this population. PMID: 32960338 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - September 21, 2020 Category: General Medicine Authors: Hasenöhrl T, Palma S, Huber DF, Zdravkovic A, Crevenna R Tags: Wien Klin Wochenschr Source Type: research

CDC25c expression in patients with myelofibrosis is associated with stronger myeloproliferation and shorter overall survival.
CONCLUSION: Our data suggest that higher CDC25c expression is associated with more proliferative phenotype of myelofibrosis and is prognostic of worse survival. Future studies investigating these interesting associations are warranted. PMID: 32945945 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - September 17, 2020 Category: General Medicine Authors: Galusic D, Lucijanic M, Livun A, Radman M, Lucijanic J, Drmic Hofman I, Kusec R Tags: Wien Klin Wochenschr Source Type: research

A  data-driven framework for introducing predictive analytics into expanded program on immunization in Pakistan.
CONCLUSION: The proposed framework in this study is a step forward towards a data-driven approach and provides a set of machine learning techniques to utilise predictive analytics. Hence, this can reinforce immunization programs by expediting targeted action to reduce drop-outs. PMID: 32945946 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - September 17, 2020 Category: General Medicine Authors: Qazi S, Usman M, Mahmood A Tags: Wien Klin Wochenschr Source Type: research