A bibliometric analysis of the 100 most-cited clinical articles in the research of intracranial artery stenosis and intracranial atherosclerosis
CONCLUSION: The findings of this study provide novel insight into this field and will facilitate future research endeavors.PMID:38628533 | PMC:PMC11021113 | DOI:10.25259/SNI_1030_2023 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Yudai Hirano Satoru Miyawaki Yusuke Sakaguchi Satoshi Koizumi Hiroki Hongo Nobuhito Saito Source Type: research
Extract of Gualou-Xiebai Herb Pair Improves Lipid Metabolism Disorders by Enhancing the Reverse Cholesterol Transport in Atherosclerosis Mice
CONCLUSION: In summary, our results suggested that GXE improved lipid metabolism disorders by enhancing RCT, providing a scientific basis for the clinical use of GXE in AS treatment.PMID:38629368 | DOI:10.2174/0115672026308438240405055719 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Yarong Liu Tian Wang Lidan Ding Zhenglong Li Yexiang Zhang Min Dai Hongfei Wu Source Type: research
Correction: Opening new vistas on obsessive-compulsive disorder with the observing response task
Cogn Affect Behav Neurosci. 2024 Apr 17. doi: 10.3758/s13415-024-01187-8. Online ahead of print.NO ABSTRACTPMID:38630212 | DOI:10.3758/s13415-024-01187-8 (Source: Cognitive, Affective and Behavioral Neuroscience)
Source: Cognitive, Affective and Behavioral Neuroscience - April 17, 2024 Category: Neuroscience Authors: Luise Pickenhan Amy L Milton Source Type: research
Overview: Research on the Genetic Architecture of the Developing Cerebral Cortex in Norms and Diseases
Methods Mol Biol. 2024;2794:1-12. doi: 10.1007/978-1-0716-3810-1_1.ABSTRACTThe human brain is characterized by high cell numbers, diverse cell types with diverse functions, and intricate connectivity with an exceedingly broad surface of the cortex. Human-specific brain development was accomplished by a long timeline for maturation from the prenatal period to the third decade of life. The long timeline makes complicated architecture and circuits of human cerebral cortex possible, and it makes human brain vulnerable to intrinsic and extrinsic insults resulting in the development of variety of neuropsychiatric disorders. Unra...
Source: Mol Biol Cell - April 17, 2024 Category: Molecular Biology Authors: Mariko Y Momoi Source Type: research
Structural, Functional, and Genetic Changes Surrounding Electrodes Implanted in the Brain
Acc Chem Res. 2024 Apr 17. doi: 10.1021/acs.accounts.4c00057. Online ahead of print.ABSTRACTConspectusImplantable neurotechnology enables monitoring and stimulating of the brain signals responsible for performing cognitive, motor, and sensory tasks. Electrode arrays implanted in the brain are increasingly used in the clinic to treat a variety of sources of neurological diseases and injuries. However, the implantation of a foreign body typically initiates a tissue response characterized by physical disruption of vasculature and the neuropil as well as the initiation of inflammation and the induction of reactive glial states...
Source: Cell Research - April 17, 2024 Category: Cytology Authors: Bhavna Gupta Akash Saxena Mason L Perillo Lauren C Wade-Kleyn Cort H Thompson Erin K Purcell Source Type: research
Extract of Gualou-Xiebai Herb Pair Improves Lipid Metabolism Disorders by Enhancing the Reverse Cholesterol Transport in Atherosclerosis Mice
CONCLUSION: In summary, our results suggested that GXE improved lipid metabolism disorders by enhancing RCT, providing a scientific basis for the clinical use of GXE in AS treatment.PMID:38629368 | DOI:10.2174/0115672026308438240405055719 (Source: Cell Research)
Source: Cell Research - April 17, 2024 Category: Cytology Authors: Yarong Liu Tian Wang Lidan Ding Zhenglong Li Yexiang Zhang Min Dai Hongfei Wu Source Type: research
Association between urinary BTEX metabolites and dyslexic odds among school-aged children
Environ Sci Pollut Res Int. 2024 Apr 17. doi: 10.1007/s11356-024-33268-z. Online ahead of print.ABSTRACTBenzene, toluene, ethylbenzene, and xylene (BTEX) are ubiquitous in the environment, and all of them can cause neurotoxicity. However, the association between BTEX exposure and dyslexia, a disorder with language network-related regions in left hemisphere affected, remains unclear. We aimed to assess the relationship between BTEX exposure and dyslexic odds among school-aged children. A case-control study, including 355 dyslexics and 390 controls from three cities in China, was conducted. Six BTEX metabolites were measured...
Source: Environmental Science and Pollution Research International - April 17, 2024 Category: Environmental Health Authors: Rundong Liu Yanjian Wan Bing Zhu Qi Liu Haoxue Wang Qi Jiang Yanan Feng Kaiheng Zhu Shuai Zhao Zhen Xiang Ying Zhu Ranran Song Source Type: research
Analyzing the risk factors of unilateral trigeminal neuralgia under neurovascular compression
ConclusionOur findings suggest that the side of NVC, the compressing vessel, and the microstructure of the cisternal segment of CN V are associated with the risk of C-ITN. Furthermore, microstructural changes observed in the cisternal segment of CN V on the unaffected side of C-ITN patients with NVC indicate possible indirect effects on the CN V to some extent. (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - April 17, 2024 Category: Neuroscience Source Type: research
Neuroprotective Effect of Sterculia setigera Leaves Hydroethanolic Extract
AbstractPlants are a valuable source of information for pharmacological research and new drug discovery. The present study aimed to evaluate the neuroprotective potential of the leaves of the medicinal plantSterculia setigera. In vitro, the effect ofSterculia setigera leaves dry hydroethanolic extract (SSE) was tested on cultured cerebellar granule neurons (CGN) survival when exposed to hydrogen peroxide (H2O2) or 6-hydroxydopamine (6-OHDA), using the viability probe fluorescein diacetate (FDA), a lactate dehydrogenase (LDH) activity assay, an immunocytochemical staining against Gap 43, and the quantification of the expres...
Source: Journal of Molecular Neuroscience - April 17, 2024 Category: Neuroscience Source Type: research
Tributyltin (TBT) toxicity: Effects on enteric neuronal plasticity and intestinal barrier of rats' duodenum
Tributyltin (TBT) is a biocide used in the formulation of antifouling paints and it is highly harmful. Despite the ban, the compound persists in the environment, contaminating marine foodstuffs and household products. Therefore, considering the route of exposure to the contaminant, the gastrointestinal tract (GIT) acts as an important barrier against harmful substances and is a potential biomarker for understanding the consequences of these agents. This work aimed to evaluate histological and neuronal alterations in the duodenum of male Wistar rats that received 20 ng/g TBT and 600 ng/g via gavage for 30 consecutive d...
Source: Autonomic Neuroscience: Basic and Clinical - April 17, 2024 Category: Neuroscience Authors: I.C.C.S. Oliveira, G.P. Marinsek, L.V.B. Correia, R.C.B. da Silva, I.B. Castro, R.B. Mari Source Type: research
Effects of oral administration of ondansetron, a 5-HT3 receptor antagonist, on anxiety-related behaviors and colonic hypercontractility in repeated stress-induced mice
This study aimed to investigate the effects of ondansetron, a 5-HT3 receptor antagonist, on locomotor activity, anxiety-related behaviors, and colonic functions in repeated water avoidance stress. (Source: Autonomic Neuroscience: Basic and Clinical)
Source: Autonomic Neuroscience: Basic and Clinical - April 17, 2024 Category: Neuroscience Authors: Affan Waemong, Sarunnuch Sattayachiti, Dania Cheaha, Nipaporn Konthapakdee Source Type: research
Choroid plexus enlargement in amyotrophic lateral sclerosis patients and its correlation with clinical disability and blood-CSF barrier permeability
ConclusionOur study first demonstrates CP enlargement in vivo in ALS patients, and continues to suggest an important pathogenetic role for CP abnormalities in ALS. Moreover, assessing CP volume is likely a noninvasive and easy-to-implement approach for screening BCSFB dysfunction in ALS patients. (Source: Fluids and Barriers of the CNS)
Source: Fluids and Barriers of the CNS - April 17, 2024 Category: Neuroscience Source Type: research
Peri-implantitis with a potential axis to brain inflammation: an inferential review
This study found similarities between PI and PD development, maintenance, and in the bacterial agents located around the teeth (periodontitis) or dental implants (peri-implantitis). Through the cardiovascular system, these pathologies may also affect blood-brain barrier permeability. Furthermore, scientific evidence has suggested that microorganisms from PI (as in PD) can be recognized by trigeminal fiber endings and start inflammatory responses into the trigeminal ganglion. In addition, bacteria can traverse from the mouth to the brain through the lymphatic system. Consequently, the immune system increases inflammatory me...
Source: Odontology - April 17, 2024 Category: Dentistry Source Type: research
Neurology Training and Medical Education in Resource-Limited Settings: Building and Growing the First Neurology Residency Program in East Africa
Semin Neurol 2024; 44: 147-158 DOI: 10.1055/s-0044-1785539The burden of neurological disease disproportionately affects low- and middle-income countries, where the lowest number of neurologists are located. Building local training opportunities in resource-limited settings is a foundational step to enhancing the neurological workforce and improving access to neurological care in these regions. In this article, we describe the development and growth of the first neurology residency program in East Africa, which was established in 2006 at Zewditu Memorial Hospital and the Tikur Anbessa Specialized Hospital, Addis Ababa Unive...
Source: Seminars in Neurology - April 17, 2024 Category: Neurology Authors: Belay, Hanna D. Gebrewold, Meron A. Ayele, Biniyam A. Oda, Dereje M. Kelemu, Fikru T. Zewde, Yared Z. Melkamu, Selam K. Wuhib, Mehila Z. Gugssa, Seid A. Mengesha, Abenet T. Metaferia, Guta Z. Tags: Review Article Source Type: research
Transactivator of Transcription (Tat)-Induced Neuroinflammation as a Key Pathway in Neuronal Dysfunction: A Scoping Review
AbstractThe activity of HIV-1 and its viral proteins within the central nervous system (CNS) is responsible for a wide array of neuropathological effects, resulting in a spectrum of neurocognitive deficits defined as HIV-associated neurocognitive disorders (HAND). Amongst the various viral proteins, the transactivator of transcription (Tat) remains detectable even with effective antiretroviral therapy (ART) and suppressed viremia, highlighting the significance of this protein in the modern ART era. Tat has been extensively researched in both fundamental and clinical settings due to its role in neuroinflammation, neuronal d...
Source: Molecular Neurobiology - April 17, 2024 Category: Neurology Source Type: research
