Neuroticism and relationship quality: A meta-analytic review
J Pers Soc Psychol. 2024 May 2. doi: 10.1037/pspi0000463. Online ahead of print.ABSTRACTRegardless of participant age, length of relationship, country of origin, and numerous other factors, prior research has established a robust negative association between neuroticism and relationship quality. As so much has already been studied on the topic of neuroticism and relationship quality, this study explored the association between neuroticism and relationship quality using meta-analytic methodology, examined moderators, and outlined future studies for the field. After searching through databases and the references of included ...
Source: Journal of Personality and Social Psychology - May 2, 2024 Category: Psychiatry & Psychology Authors: Charlotte R Esplin Benjamin D Rasmussen Stephen G Hatch Alan J Hawkins Scott R Braithwaite Source Type: research
Fear, defense, and emotion: A neuroethological understanding of the negative valence research domain criteria
We describe the close correspondence between predatory imminence continuum theory (PICT) and the National Institute of Mental Health's Research Domain Criteria (RDoC) for negative valence. RDoC's negative valence constructs relate aversively motivated behavioral reactions to various levels of threat. PICT divides defensive responses into distinct modes that vary along a continuum of the psychological closeness of predatory threat. While there is a close correspondence between PICT modes and negative valence threat constructs, based on PICT, we describe some potential elaborations of RDoC constructs. Both have consonant vie...
Source: The American Psychologist - May 2, 2024 Category: Psychiatry & Psychology Authors: Michael S Fanselow Ann N Hoffman Source Type: research
Expression analysis of necroptosis related genes and lncRNAs in patients with pituitary neuroendocrine tumors
Pathol Res Pract. 2024 Apr 30;258:155332. doi: 10.1016/j.prp.2024.155332. Online ahead of print.ABSTRACTNecroptosis can either be the cause of tumorigenesis or it can impede its process. Recently, it has been proved that long non-coding RNAs (lncRNAs) have different crucial roles at cellular level, especially on cell death. Regarding the important role of necroptosis and lncRNAs in the pathogenesis of different cancers, especially pituitary adenomas (PAs), we assessed expression levels of two necroptosis related genes, namely TRADD and BIRC2, in addition to three related lncRNAs, namely FLVCR1-DT, MAGI2-AS3, and NEAT1 in P...
Source: Pathology, Research and Practice - May 2, 2024 Category: Pathology Authors: Arian Askari Mohammad Reza Darabi Solat Eslami Elena Jamali Guive Sharifi Soudeh Ghafouri-Fard Nader Akbari Dilmaghani Source Type: research
Visual imagery deficits in posterior cortical atrophy
Cogn Neuropsychol. 2024 May 2:1-16. doi: 10.1080/02643294.2024.2346362. Online ahead of print.ABSTRACTVisual imagery has a close overlapping relationship with visual perception. Posterior cortical atrophy (PCA) is a neurodegenerative syndrome marked by early impairments in visuospatial processing and visual object recognition. We asked whether PCA would therefore also be marked by deficits in visual imagery, tested using objective forced-choice questionnaires, and whether imagery deficits would be selective for certain properties. We recruited four patients with PCA and a patient with integrative visual agnosia due to bila...
Source: Cognitive Neuropsychology - May 2, 2024 Category: Psychiatry & Psychology Authors: Connor D Dietz Andrea Albonico Jeremy J Tree Jason J S Barton Source Type: research
Predicting the cognitive impairment with multimodal ophthalmic imaging and artificial neural network for community screening
CONCLUSIONS: This study demonstrates retinal spectral signature alteration, neurodegeneration and angiopathy occur concurrently in cognitive impairment. The combination of multimodal ophthalmic imaging and BPNN can be a useful tool for predicting cognitive impairment with high performance for community screening.PMID:38697799 | DOI:10.1136/bjo-2023-323283 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Zi Jin Xuhui Chen Chunxia Jiang Ximeng Feng Da Zou Yanye Lu Jinying Li Qiushi Ren Chuanqing Zhou Source Type: research
Differential effects of high-fat diet on endocrine, metabolic and depressive-like behaviors in male and female rats
Appetite. 2024 Apr 30:107389. doi: 10.1016/j.appet.2024.107389. Online ahead of print.ABSTRACTThe complications of obesity extend beyond the periphery to the central nervous system (CNS) and include an increased risk of developing neuropsychiatric co-morbidities like depressive illness. Preclinical studies support this concept, including studies that have examined the effects of high-fat diet (HFD) on depressive-like behaviors. Although women are approximately two-fold more likely to develop depressive illness compared to men, most preclinical studies have focused on the effects of HFD in male rodents. Accordingly, the goa...
Source: Appetite - May 2, 2024 Category: Nutrition Authors: J L Woodruff M K Bykalo F Z Loyo-Rosado E S Maissy A T Sadek M Hersey J M Erichsen N D Maxwell M A Wilson S K Wood P Hashemi C A Grillo L P Reagan Source Type: research
Comparing Neuromuscular Blockade Measurement Between Upper Arm (TOF Cuff ®) and Eyelid (TOF Scan®) Using Mivacurium during General Anesthesia
CONCLUSIONS When measurement on the limb is not possible, TOF-Scan on the eyelid can be an alternative for TOF-Cuff on the upper arm, if the time to relaxation is multiplied by at least 8, which is enough for 90% of patients.PMID:38693676 | DOI:10.12659/MSM.943630 (Source: Medical Science Monitor)
Source: Medical Science Monitor - May 2, 2024 Category: Research Authors: Pawe ł Radkowski Jakub Ru ść Mariusz K ęska Klaudia Sztaba Source Type: research
Temporal dynamics of ocular torsion and vertical vergence during visual, vestibular, and visuovestibular rotations
This study investigated the onset times of ocular torsion (OT) and vertical vergence (VV) during visual, vestibular, and visuovestibular motion, as well as their relative decay rates following prolonged optokinetic stimulations. Temporal characteristics were retrieved from three separate investigations where the level of visual clutter and acceleration were controlled. Video eye-tracking was used to retrieve the eye-movement parameters from a total of 41 healthy participants across all trials. Ocular torsion consistently initiated earlier than vertical vergence, particularly evident under intensified visual information den...
Source: Brain Research - May 2, 2024 Category: Neurology Authors: Tobias Wibble Source Type: research
Impact of Abl2/Arg Deficiency on Anxiety and Depressive Behaviors in mice
In this study, we developed Abl2/Arg knockout (arg-/-) mice to explore its impact on sensory/motor functions and emotion-related behaviors. Our findings show that arg-/- mice exhibit normal growth and phenotypic characteristics, closely resembling their wild-type (WT) counterparts. Behavioral tests, including the elevated plus maze, marble-burying behavior test, and open field test, indicated pronounced anxiety-like behaviors in arg-/- mice compared to WT mice. Furthermore, in the tail suspension test, arg-/- mice showed a significant decrease in mobility time, suggesting depressive-like behavior. Conversely, in the Y-maze...
Source: Brain Research - May 2, 2024 Category: Neurology Authors: Xiaojuan Yao Ruiying Chen Hongting Chen Anthony Koleske Xiao Xiao Source Type: research
The alpha1a antagonist tamsulosin impairs memory acquisition, consolidation and retrieval in a novel object recognition task in mice
In conclusion, tamsulosin impaired memory acquisition, consolidation and retrieval in an object recognition task in mice, thus affecting memory performance in a non-specific phase manner. These findings contribute to our understanding of the potential adverse effects of tamsulosin, and shed light on the role played by α1-adrenoceptors, particularly α1A- subtype, in cognitive processes.PMID:38697302 | DOI:10.1016/j.bbr.2024.115027 (Source: Brain Research)
Source: Brain Research - May 2, 2024 Category: Neurology Authors: Victor A D Holanda Matheus C Oliveira Carina I de Oliveira Torres Clarissa de Almeida Moura Hindiael Belchior Edilson D da Silva Junior Elaine C Gavioli Source Type: research
Impact of Abl2/Arg Deficiency on Anxiety and Depressive Behaviors in mice
In this study, we developed Abl2/Arg knockout (arg-/-) mice to explore its impact on sensory/motor functions and emotion-related behaviors. Our findings show that arg-/- mice exhibit normal growth and phenotypic characteristics, closely resembling their wild-type (WT) counterparts. Behavioral tests, including the elevated plus maze, marble-burying behavior test, and open field test, indicated pronounced anxiety-like behaviors in arg-/- mice compared to WT mice. Furthermore, in the tail suspension test, arg-/- mice showed a significant decrease in mobility time, suggesting depressive-like behavior. Conversely, in the Y-maze...
Source: Behavioural Brain Research - May 2, 2024 Category: Neurology Authors: Xiaojuan Yao Ruiying Chen Hongting Chen Anthony Koleske Xiao Xiao Source Type: research
The alpha1a antagonist tamsulosin impairs memory acquisition, consolidation and retrieval in a novel object recognition task in mice
In conclusion, tamsulosin impaired memory acquisition, consolidation and retrieval in an object recognition task in mice, thus affecting memory performance in a non-specific phase manner. These findings contribute to our understanding of the potential adverse effects of tamsulosin, and shed light on the role played by α1-adrenoceptors, particularly α1A- subtype, in cognitive processes.PMID:38697302 | DOI:10.1016/j.bbr.2024.115027 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - May 2, 2024 Category: Neurology Authors: Victor A D Holanda Matheus C Oliveira Carina I de Oliveira Torres Clarissa de Almeida Moura Hindiael Belchior Edilson D da Silva Junior Elaine C Gavioli Source Type: research
Virtual dynamic interaction games reveal impaired multisensory integration in women with migraine
CONCLUSION: The virtual dynamic game approach showed for the first time that the gaming performance of patients with migraine without aura was negatively affected by the addition of auditory, verbal, and haptic stimuli onto visual stimuli. Multisensory integration of sensory modalities including haptic stimuli is disturbed even in the interictal period in women with migraine. Virtual games can be employed to assess the impact of sensory problems in the course of the disease. Also, sensory training could be a potential therapy target to improve multisensory processing in migraine.PMID:38693749 | DOI:10.1111/head.14720 (Source: Headache)
Source: Headache - May 2, 2024 Category: Neurology Authors: Merve S Ince Ilkem Guzel Merve C Akgor Meltem Bahcelioglu Kutluk B Arikan Amr Okasha Sabahat Sengezer Hayrunnisa Bolay Source Type: research
Non-invasive high-frequency ventilation in newborn infants with respiratory distress
CONCLUSIONS: For initial RS, we are very uncertain if using nHFV compared to invasive respiratory therapy affects clinical outcomes. However, nHFV may reduce intubation when compared to nCPAP. For planned extubation, nHFV may reduce the risk of reintubation compared to nCPAP and nIPPV. nHFV may reduce the risk of CLD when compared to nCPAP. Following initial non-invasive respiratory support failure, nHFV when compared to nIPPV may result in little to no difference in intubation. Large trials, particularly in high-income settings, are needed to determine the role of nHFV in initial RS and following the failure of other non-...
Source: Cochrane Database of Systematic Reviews - May 2, 2024 Category: General Medicine Authors: Mohamed E Abdel-Latif Olive Tan Michelle Fiander David A Osborn Source Type: research
Dexmedetomidine for analgesia and sedation in newborn infants receiving mechanical ventilation
CONCLUSIONS: Despite the increasing use of dexmedetomidine, there is insufficient evidence supporting its routine use for analgesia and sedation in newborn infants on mechanical ventilation. Furthermore, data on dexmedetomidine safety are scarce, and there are no data available on its long-term effects. Future studies should address the efficacy, safety, and long-term effects of dexmedetomidine as a single drug therapy for sedation and analgesia in newborn infants.PMID:38695625 | DOI:10.1002/14651858.CD012361.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - May 2, 2024 Category: General Medicine Authors: Jia Yi Lim Chin Jin Ker Nai Ming Lai Olga Romantsik Michelle Fiander Kenneth Tan Source Type: research
