Notice of Special Interest: Administrative Supplements to Support Collection of Spanish Normative Data and Determination of Test-Retest Reliability Estimates of Neuropsychological Tests for NCI Clinical Trials
Notice NOT-CA-24-040 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 22, 2024 Category: Research Source Type: funding

Using Neuromodulation to Characterize the Continuum of Pathophysiology Between Substance Use and Mental Health Disorders (R01 Clinical Trial Required)
Funding Opportunity RFA-DA-25-035 from the NIH Guide for Grants and Contracts. This NOFO seeks applications from the SUD and MHD research communities that coordinate efforts to characterize the effects of neuromodulation on brain circuits and behaviors relevant to both SUD and MHD. To accomplish this goal, studies would specify inclusion/exclusion criteria to capture variance in both SUD and MHD symptoms. Further, studies would include measures of engagement of circuit-level targets in response to neuromodulation and dimensional measures of cognition and behavior relevant to both SUD and MHD. This research approach uses...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 15, 2024 Category: Research Source Type: funding

Neuropathological Interactions Between COVID-19 and ADRD (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-24-203 from the NIH Guide for Grants and Contracts. This NOFO will solicit R01 applications that propose studies in animal, cell culture, and/or human tissue models to elucidate the mechanisms by which COVID-19 interacts with and/or modulates AD/ADRD-relevant phenotypes. Either the model itself or the experimental readouts will be required to incorporate AD/ADRD risk factors, pathologies, or relevant comorbidities. To this end, proposals can focus on one or more of the following: - Mechanistic studies that address how COVID-19 impacts CNS pathology and cognitive outcomes when AD/ADRD pathology is...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 12, 2024 Category: Research Source Type: funding

Feasibility Trials of the NIH Music-based Interventions Toolkit for Brain Disorders of Aging (R34 Clinical Trial Required)
Funding Opportunity PAR-24-168 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to reissue PAR-24-256 "Feasibility Trials of the NIH Music-based Interventions Toolkit for Brain Disorders of Aging (R34 Clinical Trial Required)" in order to support proof-of-concept feasibility trials guided by the NIH Music-based Interventions (MBI) Toolkit for research on brain disorders of aging. These early stage clinical trials will generate evidence supporting the validity of the NIH MBI Toolkits guiding principles as well as the necessary pilot data to assess the feasibility of...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 10, 2024 Category: Research Source Type: funding

Protective Strategies to Reduce Amyloid Related Imaging Abnormalities (ARIA) After Anti-Amyloid Beta Immunotherapy (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-24-198 from the NIH Guide for Grants and Contracts. This initiative is designed to promote discovery of cellular and molecular mechanisms that underlie brain blood vessels responses to passive anti-beta-amyloid immunotherapy that result in amyloid-related imaging abnormalities (ARIA). The goal is to establish an understanding of molecular mechanisms that can be targeted to protect the blood brain barrier (BBB), and thus the brain blood vessels, during therapeutic interventions that target beta-amyloid. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 10, 2024 Category: Research Source Type: funding

Education Activities for Responsible Analyses of Complex, Large-Scale Data (R25- Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-25-039 from the NIH Guide for Grants and Contracts. This concept proposes to advance methodological rigor in NIDA-relevant research by supporting training on the responsible analyses of complex, large-scale datasets involving brain, behavioral, genomic, and socioenvironmental data through: 1. Courses for Skills Development 2. Curriculum or Methods Development (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 9, 2024 Category: Research Source Type: funding

Request for Information (RFI): Improving research frameworks to enable rigorous study of the effects of racism on brain and behavioral health across the lifespan
Notice NOT-MH-24-190 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 8, 2024 Category: Research Source Type: funding

Mechanistic and Hemodynamic Basis of Diffuse White Matter Disease in Vascular Contributions to Cognitive Impairment and Dementia (VCID)(R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-24-196 from the NIH Guide for Grants and Contracts. (Reissue of RFA-NS-16-021, PAR-18-413, RFA-NS-19-039) Diffuse brain white matter disease is highly prevalent in the elderly, and has been clinically associated with vascular contributions to cognitive impairment and dementia (VCID) in both men and women. Diffuse white matter disease is thought to include a variety of pathologies including demyelination and/or fiber loss due to multifocal infarction and local ischemia. It is often accompanied by arteriosclerosis in deep penetrating arteries, multiple infarcts in the basal ganglia, brainstem or ce...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 5, 2024 Category: Research Source Type: funding

Tools and resources to understand the vascular pathophysiology of in vivo neuroimaging findings in ARIA (U24 - Clinical Trials Not Allowed)
Funding Opportunity RFA-NS-24-034 from the NIH Guide for Grants and Contracts. The purpose of this Alzheimers Disease-Related Dementia (ADRD) initiative is to promote the development and distribution of innovative technologies, methods, protocols, and biomedical materials that enhance combined human neuropathology and neuroimaging research with data aimed at understanding the underlying pathophysiology of in vivo imaging results typically associated with vascular contributions to cognitive impairment and dementia (VCID) in TBI-related dementia and other ADRD diagnoses. Resources developed under this FOA must follow open...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 28, 2024 Category: Research Source Type: funding

NINDS Program Project Grant (P01 Clinical Trial Optional)
Funding Opportunity PAR-24-169 from the NIH Guide for Grants and Contracts. This notice of opportunity announcement (NOFO) is issued by the National Institute of Neurological Disorders and Stroke to enable submission of program project grant applications that propose to conduct innovative, interactive research to answer significant scientific questions that are important for the mission of NINDS, via a synergistic collaboration between outstanding scientists who might not otherwise collaborate. The program project grant is designed to support research in which the funding of several interdependent highly meritorious pro...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 27, 2024 Category: Research Source Type: funding

AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
Funding Opportunity PAR-24-165 from the NIH Guide for Grants and Contracts. The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core grants (P30) to support HIV/AIDS Research Centers (ARC). The ARC is intended to provide infrastructure support that facilitates the development of high impact science in HIV/AIDS and mental health that is relevant to the NIMH mission. This Notice of Funding Opportunity (NOFO) intends to support innovative, interdisciplinary research in several areas, including basic, NeuroHIV, behavioral and social, integrated biobehavioral, app...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 22, 2024 Category: Research Source Type: funding

Developmental AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
Funding Opportunity PAR-24-164 from the NIH Guide for Grants and Contracts. The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core grants (P30) to support HIV/AIDS Research Centers (ARC). The ARC is intended to provide infrastructure support that facilitates the development of high impact science in HIV/AIDS and mental health that is relevant to the NIMH mission. This Notice of Funding Opportunity (NOFO) intends to support innovative, interdisciplinary research in several areas, including basic, NeuroHIV, behavioral and social, integrated biobehavioral, app...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 22, 2024 Category: Research Source Type: funding

BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)
Funding Opportunity RFA-NS-24-016 from the NIH Guide for Grants and Contracts. Reissue: RFA-NS-21-023 - The purpose of this Funding Opportunity Announcement (FOA) is to encourage investigators to pursue translational activities and small clinical studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Sign...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 20, 2024 Category: Research Source Type: funding

New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)
Funding Opportunity PAR-24-161 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to encourage multidisciplinary investigators to submit applications developing exploratory, highly novel new approaches, or innovative applications of existing approaches to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease, by improving repeated measures across longer epochs of the ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 19, 2024 Category: Research Source Type: funding

New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)
Funding Opportunity PAR-24-160 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to encourage multidisciplinary investigators to develop new approaches or apply existing approaches in novel ways to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease. Research can include healthy human participants of any age, specific clinical groups such as those with cognitive, m...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 19, 2024 Category: Research Source Type: funding