GSE255474 Characterisation of the epidermal diurnal transcriptome of mice with K14-Cre-driven Bmal1 knockout
Contributor : Thomas MortimerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo preserve a state of health, mammals employ an integrated network of molecular oscillators to drive daily rhythms of tissue-specific homeostatic processes. Importantly, the output, structure and coherence of this network is compromised by physiological ageing, disease and lifestyle changes. Yet, the key signalling nodes in this network, their underlying mechanisms of communication, and potential for therapeutic intervention, remain undefined. To dissect this system, we construct a minimal clock network con...
Source: GEO: Gene Expression Omnibus - May 2, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE266046 Single cell RNA-sequencing analysis of astrocyte-to-neuron conversion in 5xFAD mouse hippocampus
Contributors : Zheng Wu ; Liang Xu ; Yu Xie ; Gong ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusCollectively, our findings demonstrate that NeuroD1 significantly alters the transcriptomic landscape of astrocytes, suggesting a role for NeuroD1 in neuronal fate reprogramming. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - May 2, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE190032 Characterisation of the epidermal diurnal transcriptome of mice with tissue-specific circadian clock activity [LD]
Contributor : Thomas MortimerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo preserve a state of health, mammals employ an integrated network of molecular oscillators to drive daily rhythms of tissue-specific homeostatic processes. Importantly, the output, structure and coherence of this network is compromised by physiological ageing, disease and lifestyle changes. Yet, the key signalling nodes in this network, their underlying mechanisms of communication, and potential for therapeutic intervention, remain undefined. To dissect this system, we construct a minimal clock network con...
Source: GEO: Gene Expression Omnibus - May 2, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE190034 Characterisation of the epidermal circadian transcriptome of mice with tissue-specific circadian clock activity [DD]
Contributor : Thomas MortimerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo preserve a state of health, mammals employ an integrated network of molecular oscillators to drive daily rhythms of tissue-specific homeostatic processes. Importantly, the output, structure and coherence of this network is compromised by physiological ageing, disease and lifestyle changes. Yet, the key signalling nodes in this network, their underlying mechanisms of communication, and potential for therapeutic intervention, remain undefined. To dissect this system, we construct a minimal clock network con...
Source: GEO: Gene Expression Omnibus - May 2, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE231474 Infiltration of monocyte-derived macrophages perturbs the CNS metabolic landscape, licensing arginine catabolism and augments neuro-inflammation
Contributors : Martina Kerndl ; Andrea Vogel ; Andrea Komljenovic ; Omar Sharif ; Gernot SchabbauerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusInflammatory responses are associated with monocyte recruitment into inflamed tissues, where they differentiate into monocyte-derived macrophages (moMACs). While tissue-specific reprogramming of moMACs is well-established, how they alter tissue metabolism remains unclear. Here, using a murine neuro-inflammation model coupled with genetic fate-mapping, metabolomics and metabolite imaging, we identify that central nervous system (CNS) mo...
Source: GEO: Gene Expression Omnibus - May 2, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Capitella teleta gets left out: possible evolutionary shift causes loss of left tissues rather than increased neural tissue from dominant-negative BMPR1
The evolution of central nervous systems (CNSs) is a fascinating and complex topic; further work is needed to understand the genetic and developmental homology between organisms with a CNS. Research into a lim... (Source: Neural Development)
Source: Neural Development - May 2, 2024 Category: Neurology Authors: Nicole B. Webster and N éva P. Meyer Tags: Research Source Type: research
Reflections on Participation at Home, As Self-Reported by Young People with Cerebral Palsy
. (Source: Developmental Neurorehabilitation)
Source: Developmental Neurorehabilitation - May 2, 2024 Category: Neurology Authors: Jacinta R QuartermaineTanya A RoseMegan L AuldLeanne M Johnstona The University of Queensland, Brisbane, Australiab Children ’s Motor Control Research Collaboration, Brisbane, Australiac Choice, Passion, Life, Brisbane, Australiad Queensland Cerebral Pa Source Type: research
Female RNA concussion (FeRNAC) study: assessing hormone profiles and salivary RNA in females with concussion by emergency departments in New Zealand: a study protocol
Females of reproductive age with concussion report a greater number of symptoms that can be more severe and continue for longer than age matched males. Underlying mechanisms for sex differences are not well un... (Source: BMC Neurology)
Source: BMC Neurology - May 2, 2024 Category: Neurology Authors: Natalie Hardaker, Doug King, Patria A. Hume, Tom Stewart, Stacy Sims, Indira Basu, Blair Shilton and James Selfe Tags: Study Protocol Source Type: research
Assessing the impact of migraine on benign paroxysmal positional vertigo symptoms and recovery
During episodes of benign paroxysmal positional vertigo (BPPV), individuals with migraine, compared with individuals without migraine, may experience more severe vestibular symptoms because of their hyperexcit... (Source: BMC Neurology)
Source: BMC Neurology - May 2, 2024 Category: Neurology Authors: Seda Çakır, Aysenur Sahin, Ozlem Gedik-Soyuyuce, Zeynep Gence Gumus, İbrahim Sertdemir, Nazım Korkut and Pınar Yalınay Dikmen Tags: Research Source Type: research
Maternal immunoglobulin G affects brain development of mouse offspring
Maternal immunoglobulin (Ig)G is present in breast milk and has been shown to contribute to the development of the immune system in infants. In contrast, maternal IgG has no known effect on early childhood bra... (Source: Journal of Neuroinflammation)
Source: Journal of Neuroinflammation - May 2, 2024 Category: Neurology Authors: Mizuki Sadakata, Kazuki Fujii, Ryosuke Kaneko, Emi Hosoya, Hisako Sugimoto, Reika Kawabata-Iwakawa, Tetsuhiro Kasamatsu, Shoko Hongo, Yumie Koshidaka, Akinori Takase, Takatoshi Iijima, Keizo Takao and Tetsushi Sadakata Tags: Research Source Type: research
Evaluation of differences in expression pattern of three isoforms of the transforming growth factor beta in patients with lumbosacral stenosis
. (Source: Cell Cycle)
Source: Cell Cycle - May 2, 2024 Category: Cytology Authors: Dawid Soba ńskiPaweł BogdałRafał StaszkiewiczMałgorzata SobańskaMichał FilipowiczRyszard Adam CzepkoDamian StrojnyBeniamin Oskar Grabareka Department of Neurosurgery, Szpital sw. Rafala in Cracow, Cracow, Polandb Collegium Medicum, WSB University, Source Type: research
The impact of specialized nursing care at fracture sites coordinated with disease progression monitoring in thoracolumbar spine fractures
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - May 2, 2024 Category: Neuroscience Authors: Juan LiuGuiqi ZhangQiuyan ZhaoJuan WangJing ZhangChuanyi Baia Department of Orthopedics, The Second Affiliated Hospital, Xi ’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of Chinab Department of Spinal Surgery, Dalian Municipal Central H Source Type: research
Effects of simulated presence therapy on agitated behavior, cognition, and use of protective constraint among patients with senile dementia
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - May 2, 2024 Category: Neuroscience Authors: Qingyi DuanXing LiuAiling ZhangDepartment of Neurology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, People ’s Republic of China Source Type: research
Multiplanar spinopelvic fracture reduction and dual triangular osteosynthesis stabilization for complex multiplanar sacropelvic fractures
. (Source: British Journal of Neurosurgery)
Source: British Journal of Neurosurgery - May 2, 2024 Category: Neurosurgery Authors: Siddharth VankipuramPratipal KalsiZhengyue Grace YangVittorio M RussoAntonino Russoa Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UKb Department of Neurosurgery, Imperial College Healthcare NHS Trust, London, UK Source Type: research
Recovery After Sport-Related Concussion in Collegiate Athletes With Self-Reported Pre-Injury Migraines
Journal of Neurotrauma, Ahead of Print. (Source: Journal of Neurotrauma)
Source: Journal of Neurotrauma - May 2, 2024 Category: Neurology Authors: Douglas P. Terry Jacob Jo Kristen L. Williams Bruce A. Maxwell Paul D. Berkner Grant L. Iverson Scott L. Zuckerman Source Type: research
