The development of the adult nervous system in the annelid Owenia fusiformis
The evolutionary origins of animal nervous systems remain contentious because we still have a limited understanding of neural development in most major animal clades. Annelids — a species-rich group with centr... (Source: Neural Development)
Source: Neural Development - February 21, 2024 Category: Neurology Authors: Allan M. Carrillo-Baltodano, Rory D. Donnellan, Elizabeth A. Williams, G áspár Jékely and José M. Martín-Durán Tags: Research Source Type: research
A cell atlas of the larval Aedes aegypti ventral nerve cord
Mosquito-borne diseases account for nearly 1 million human deaths annually, yet we have a limited understanding of developmental events that influence host-seeking behavior and pathogen transmission in mosquit... (Source: Neural Development)
Source: Neural Development - January 31, 2024 Category: Neurology Authors: Chang Yin, Takeshi Morita and Jay Z. Parrish Tags: Research Source Type: research
Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage
Prdm12 is an epigenetic regulator expressed in developing and mature nociceptive neurons, playing a key role in their specification during neurogenesis and modulating pain sensation at adulthood. In vitro stud... (Source: Neural Development)
Source: Neural Development - January 2, 2024 Category: Neurology Authors: Panagiotis Tsimpos, Simon Desiderio, Pauline Cabochette, Philippe Poelvoorde, Sadia Kricha, Luc Vanhamme, Coralie Poulard and Eric J. Bellefroid Tags: Brief Report Source Type: research
Imp is expressed in INPs and newborn neurons where it regulates neuropil targeting in the central complex
The generation of neuronal diversity remains incompletely understood. In Drosophila, the central brain is populated by neural stem cells derived from progenitors called neuroblasts (NBs). There are two types of N... (Source: Neural Development)
Source: Neural Development - November 29, 2023 Category: Neurology Authors: Jordan A. Munroe and Chris Q. Doe Tags: Research Source Type: research
Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells
V0v spinal interneurons are highly conserved, glutamatergic, commissural neurons that function in locomotor circuits. We have previously shown that Evx1 and Evx2 are required to specify the neurotransmitter ph... (Source: Neural Development)
Source: Neural Development - November 28, 2023 Category: Neurology Authors: Samantha J. England, Amber K. Rusnock, Amra Mujcic, Angelica Kowalchuk, Sarah de Jager, William C. Hilinski, Jos é L. Juárez-Morales, Matthew E. Smith, Ginny Grieb, Santanu Banerjee and Katharine E. Lewis Tags: Research Source Type: research
Neocortex neurogenesis and maturation in the African greater cane rat
Neocortex development has been extensively studied in altricial rodents such as mouse and rat. Identification of alternative animal models along the “altricial-precocial” spectrum in order to better model and ... (Source: Neural Development)
Source: Neural Development - October 13, 2023 Category: Neurology Authors: Oluwaseun Mustapha, Thomas Grochow, James Olopade and Simone A. Fietz Tags: Research Source Type: research
Drosophila CASK regulates brain size and neuronal morphogenesis, providing a genetic model of postnatal microcephaly suitable for drug discovery
CASK-related neurodevelopmental disorders are untreatable. Affected children show variable severity, with microcephaly, intellectual disability (ID), and short stature as common features. X-linked human CASK show... (Source: Neural Development)
Source: Neural Development - October 7, 2023 Category: Neurology Authors: Judith A. Tello, Linan Jiang, Yitshak Zohar and Linda L. Restifo Tags: Research Source Type: research
Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon
E-proteins encoded by Tcf3, Tcf4, and Tcf12 are class I basic helix-loop-helix (bHLH) transcription factors (TFs) that are thought to be widely expressed during development. However, their function in the develop... (Source: Neural Development)
Source: Neural Development - September 8, 2023 Category: Neurology Authors: Mary Jo Talley, Diana Nardini, Lisa A. Ehrman, Q. Richard Lu and Ronald R. Waclaw Tags: Research Source Type: research
Correction: Lrig1 expression identifies quiescent stem cells in the ventricular ‑subventricular zone from postnatal development to adulthood and limits their persistent hyperproliferation
(Source: Neural Development)
Source: Neural Development - May 23, 2023 Category: Neurology Authors: Hyung-song Nam and Mario R. Capecchi Tags: Correction Source Type: research
Correction: Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life
(Source: Neural Development)
Source: Neural Development - May 19, 2023 Category: Neurology Authors: Hyung-song Nam and Mario R. Capecchi Tags: Correction Source Type: research
Follicle-innervating A δ-low threshold mechanoreceptive neurons form receptive fields through homotypic competition
The mammalian somatosensory system is comprised of multiple neuronal populations that form specialized, highly organized sensory endings in the skin. The organization of somatosensory endings is essential to t... (Source: Neural Development)
Source: Neural Development - April 27, 2023 Category: Neurology Authors: Matthew B. Pomaville and Kevin M. Wright Tags: Research Source Type: research
Lrig1 expression identifies quiescent stem cells in the ventricular-subventricular zone from postnatal development to adulthood and limits their persistent hyperproliferation
We previously identified Leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1) as a marker of long-term neurogenic stem cells in the lateral wall of the adult mouse brain. The morphology of the stem cell... (Source: Neural Development)
Source: Neural Development - January 11, 2023 Category: Neurology Authors: Hyung-song Nam and Mario R. Capecchi Tags: Research Source Type: research
Primary neurons lacking the SNAREs vti1a and vti1b show altered neuronal development
Neurons are highly specialized cells with a complex morphology generated by various membrane trafficking steps. They contain Golgi outposts in dendrites, which are formed from somatic Golgi tubules. In traffic... (Source: Neural Development)
Source: Neural Development - November 22, 2022 Category: Neurology Authors: Christian Bollmann, Susanne Sch öning, Katharina Kotschnew, Julia Grosse, Nicole Heitzig and Gabriele Fischer von Mollard Tags: Research Source Type: research
Correction: A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages
(Source: Neural Development)
Source: Neural Development - October 26, 2022 Category: Neurology Authors: Marc Corrales, Benjamin T. Cocanougher, Andrea B. Kohn, Jason D. Wittenbach, Xi S. Long, Andrew Lemire, Albert Cardona, Robert H. Singer, Leonid L. Moroz and Marta Zlatic Tags: Correction Source Type: research
Dpr10 and Nocte are required for Drosophila motor axon pathfinding
The paths axons travel to reach their targets and the subsequent synaptic connections they form are highly stereotyped. How cell surface proteins (CSPs) mediate these processes is not completely understood. The D... (Source: Neural Development)
Source: Neural Development - October 21, 2022 Category: Neurology Authors: Meike Lobb-Rabe, Katherine DeLong, Rio J. Salazar, Ruiling Zhang, Yupu Wang and Robert A. Carrillo Tags: Research Source Type: research
