Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish
Previous work aimed at understanding the gene regulatory networks (GRNs) governing caudal hindbrain formation identified morphogens such as Retinoic Acid (RA) and Fibroblast growth factors (FGFs), as well as t... (Source: Neural Development)
Source: Neural Development - June 26, 2018 Category: Neurology Authors: Priyanjali Ghosh, Jennifer M. Maurer and Charles G. Sagerstr öm Tags: Research article Source Type: research
Strategies for assembling columns and layers in the Drosophila visual system
A striking feature of neural circuit structure is the arrangement of neurons into regularly spaced ensembles (i.e. columns) and neural connections into parallel layers. These patterns of organization are thoug... (Source: Neural Development)
Source: Neural Development - June 7, 2018 Category: Neurology Authors: S. Sean Millard and Matthew Y. Pecot Tags: Review Source Type: research
Assembly and maintenance of GABAergic and Glycinergic circuits in the mammalian nervous system
Inhibition in the central nervous systems (CNS) is mediated by two neurotransmitters: gamma-aminobutyric acid (GABA) and glycine. Inhibitory synapses are generally GABAergic or glycinergic, although there are ... (Source: Neural Development)
Source: Neural Development - June 7, 2018 Category: Neurology Authors: Clare R. Gamlin, Wan-Qing Yu, Rachel O. L. Wong and Mrinalini Hoon Tags: Review Source Type: research
Homeostatic plasticity in neural development
Throughout life, neural circuits change their connectivity, especially during development, when neurons frequently extend and retract dendrites and axons, and form and eliminate synapses. In spite of their cha... (Source: Neural Development)
Source: Neural Development - June 1, 2018 Category: Neurology Authors: Nai-Wen Tien and Daniel Kerschensteiner Tags: Review Source Type: research
Development, functional organization, and evolution of vertebrate axial motor circuits
Neuronal control of muscles associated with the central body axis is an ancient and essential function of the nervous systems of most animal species. Throughout the course of vertebrate evolution, motor circui... (Source: Neural Development)
Source: Neural Development - June 1, 2018 Category: Neurology Authors: Kristen P. D ’Elia and Jeremy S. Dasen Tags: Review Source Type: research
Tcf7L2 is essential for neurogenesis in the developing mouse neocortex
Generation of neurons in the embryonic neocortex is a balanced process of proliferation and differentiation of neuronal progenitor cells. Canonical Wnt signalling is crucial for expansion of radial glial cells... (Source: Neural Development)
Source: Neural Development - May 11, 2018 Category: Neurology Authors: Olga Chodelkova, Jan Masek, Vladimir Korinek, Zbynek Kozmik and Ondrej Machon Tags: Short Report Source Type: research
Astrocytes, neurons, synapses: a tripartite view on cortical circuit development
In the mammalian cerebral cortex neurons are arranged in specific layers and form connections both within the cortex and with other brain regions, thus forming a complex mesh of specialized synaptic connection... (Source: Neural Development)
Source: Neural Development - May 1, 2018 Category: Neurology Authors: Isabella Farhy-Tselnicker and Nicola J. Allen Tags: Review Source Type: research
Neural circuits driving larval locomotion in Drosophila
More than 30 years of studies into Drosophila melanogaster neurogenesis have revealed fundamental insights into our understanding of axon guidance mechanisms, neural differentiation, and early cell fate decisions... (Source: Neural Development)
Source: Neural Development - April 19, 2018 Category: Neurology Authors: Matthew Q. Clark, Aref Arzan Zarin, Arnaldo Carreira-Rosario and Chris Q. Doe Tags: Review Source Type: research
Linking neuronal lineage and wiring specificity
Brain function requires precise neural circuit assembly during development. Establishing a functional circuit involves multiple coordinated steps ranging from neural cell fate specification to proper matching ... (Source: Neural Development)
Source: Neural Development - April 13, 2018 Category: Neurology Authors: Hongjie Li, S. Andrew Shuster, Jiefu Li and Liqun Luo Tags: Review Source Type: research
Monocular enucleation alters retinal waves in the surviving eye
Activity in neurons drives afferent competition that is critical for the refinement of nascent neural circuits. In ferrets, when an eye is lost in early development, surviving retinogeniculate afferents from t... (Source: Neural Development)
Source: Neural Development - March 24, 2018 Category: Neurology Authors: Samuel Wilson Failor, Arash Ng and Hwai-Jong Cheng Tags: Research article Source Type: research
FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cord
Most oligodendrocytes of the spinal cord originate from ventral progenitor cells of the pMN domain, characterized by expression of the transcription factor Olig2. A minority of oligodendrocytes is also recogni... (Source: Neural Development)
Source: Neural Development - March 8, 2018 Category: Neurology Authors: Marie-Am élie Farreny, Eric Agius, Sophie Bel-Vialar, Nathalie Escalas, Nagham Khouri-Farah, Chadi Soukkarieh, Cathy Danesin, Fabienne Pituello, Philippe Cochard and Cathy Soula Tags: Research article Source Type: research
Transcriptional regulation of ependymal cell maturation within the postnatal brain
Radial glial stem cells within the developing nervous system generate a variety of post-mitotic cells, including neurons and glial cells, as well as the specialised multi-ciliated cells that line the walls of ... (Source: Neural Development)
Source: Neural Development - February 16, 2018 Category: Neurology Authors: Diana Vidovic, Raul Ayala Davila, Richard M. Gronostajski, Tracey J. Harvey and Michael Piper Tags: Short Report Source Type: research
Correction to: Rp58 and p27kip1 coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex
After publication of the original article [1] it was realised that there were errors in figures 2a,b,f,g, which arose as a result of preparing figures from data collected and analysed at the same time as the w... (Source: Neural Development)
Source: Neural Development - January 11, 2018 Category: Neurology Authors: Olivier Cl ément, Isabel Anne Hemming, Ivan Enghian Gladwyn-Ng, Zhengdong Qu, Shan Shan Li, Michael Piper and Julian Ik-Tsen Heng Tags: Correction Source Type: research
Novel functions of LHX2 and PAX6 in the developing telencephalon revealed upon combined loss of both genes
Patterning of the telencephalic neuroepithelium is a tightly regulated process controlled by transcription factors and signalling molecules. The cortical primordium is flanked by two signalling centres, the he... (Source: Neural Development)
Source: Neural Development - November 15, 2017 Category: Neurology Authors: Geeta Godbole, Achira Roy, Ashwin S. Shetty and Shubha Tole Tags: Short report Source Type: research
Anisotropic M üller glial scaffolding supports a multiplex lattice mosaic of photoreceptors in zebrafish retina
The multiplex, lattice mosaic of cone photoreceptors in the adult fish retina is a compelling example of a highly ordered epithelial cell pattern, with single cell width rows and columns of cones and precisely... (Source: Neural Development)
Source: Neural Development - November 15, 2017 Category: Neurology Authors: Mikiko Nagashima, Jeremy Hadidjojo, Linda K. Barthel, David K. Lubensky and Pamela A. Raymond Tags: Research article Source Type: research
