How drug prices are manipulated
I wondered whether to recommend Nuedexta for my elderly relative with worsening Alzheimer’s disease and daily spontaneous crying. Often she would deny feeling sad and couldn’t account for her sobbing.   Avanir Pharmaceuticals released Nuedexta in 2010 to treat pseudobulbar affect: involuntary emotional outbursts due to certain neurologic conditions or brain injury. I wasn’t sure Read more… How drug prices are manipulated originally appeared in (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 30, 2022 Category: General Medicine Authors: Tags: Meds Medications Source Type: blogs

We need to talk about foobaw
Last Sunday, Miami Dolphins quarterback Tua Tagovailoa was knocked down in the second quarter of a game against the Buffalo Bills and hit the back of his head on the turf. He lay there for a few seconds, then tried to stand up on wobbly legs then he collapsed, obviously slobberknocked. They took him into the locker room, then sent him out to play the second half, claiming he had passed the concussion protocol and that he had collapsed due to a leg injury, which anybody could plainly see was a lie.Last night, against the Cincinnati Bengals, he was again knocked down and hit the back of his head. This timehe lay motionless f...
Source: Stayin' Alive - September 30, 2022 Category: American Health Source Type: blogs

The Gut Microbiome Produces Metabolites that Affect Immune Cells in the Brain
Researchers here review the evidence for metabolites produced by the gut microbiome to influence the behavior of innate immune cells in the brain. The gut microbiome changes in composition with age, altering the production of metabolites and inflammatory signaling in ways that degrade tissue function throughout the body. Fixing the many resulting issues at the source by introducing a youthful mix of microbes to the aging gut is a tempting path forward, likely relatively straightforward to achieve via fecal microbiota transplantation from young individuals to old individuals. This short-cut would hopefully evade the onerous...
Source: Fight Aging! - September 30, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

" And then a Plank in Reason, broke, "
  “I am dead.” In terms of possible delusions in living human beings,Le d élire des négations—the nihilistic delusion that one is dead —evokes the most harrowing existence imaginable. The French neurologistJules Cotard first described the syndrome that bears his name (1882,English translation):I hazard the name ofdelirium of negations to designate the state of the patients ... in whom the negative disposition is carried to the highest degree. [They are] asked their name – they have no name; their age – they are ageless; where were they born – they were not born; ... if they have a headache, s...
Source: The Neurocritic - September 30, 2022 Category: Neuroscience Authors: The Neurocritic Source Type: blogs

A Mechanism by Which Herpesvirus May Accelerate Amyloid- β Aggregation Leading to Alzheimer's Disease
There is some debate over whether persistent viral infection, such as by herpesvirus, contributes meaningfully to the onset and development of Alzheimer's disease. It would be a convenient explanation, given that many people with all of the lifestyle risk factors for neurodegeneration, such as being overweight and sedentary, do not in fact go on to develop Alzheimer's. The epidemiology is mixed, however, with some studies suggesting yes, some no. Some of the positive data suggests that use of antiviral drugs lowers the risk of Alzheimer's. More recent work argues that multiple different viral infections are required for a ...
Source: Fight Aging! - September 29, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Ending gun violence in America should be a no-brainer
Brain matter was spilling out the top of the patient’s head in the trauma bay. It doesn’t take a neurosurgeon to know that this is not normal. My pager screamed, “GSW to head – ED Room 1.” Gunshot wound to head – Emergency Department Room 1. As the neurosurgery resident physician on call that night, Read more… Ending gun violence in America should be a no-brainer originally appeared in (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 29, 2022 Category: General Medicine Authors: Tags: Policy Emergency Medicine Public Health & Policy Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
September 29, 2022 Edition-----The world seems to be lurching to be overwhelmed by issues around most of the major powers being in conflict for a real risk of a global recession affecting the UK, Europe, the US and much of Asia. We seem to be in some pretty difficult times right now …In OZ Parliament is now back after the death of the Queen and it will be interesting to see how things play out and what the Budget looks like in the face of an upcoming recession.-----Major Issues.----- nation shorn of Britis...
Source: Australian Health Information Technology - September 29, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

NeuroFlow & The Tech that Jumps the Care Gaps Between Physical Check-ups & Mental Health Care
By JESSICA DaMASSA, WTF HEALTH Mental health infrastructure company, NeuroFlow, is a tech platform that integrates into care management systems and EHRs to help clinicians and care managers identify behavioral health conditions in patients as they are getting physical health exams like annual check-ups, post-partum exams, and more. Founder & CEO Chris Molaro joins us from NeuroFlow’s new headquarters just hours before their grand opening to talk about how the startup – which has raised a total $32 million, including a $20 million Series B led by Magellan Health – is helping health systems and health plans inte...
Source: The Health Care Blog - September 28, 2022 Category: Consumer Health News Authors: Christina Liu Tags: WTF Health Source Type: blogs

This Is A Very Valuable Contribution To Help Us Recognise At Least Some Of The Complexities Of Using Digital Techologies In Mental Health Care Delivery.
This appeared last week:Digital technologies in mental healthcare: creating opportunities for better care, or a new form of asylum?·        Alison Barrett·        Piers Gooding and Simon Katterl·        Wednesday, September 21, 2022Introduction by Croakey: With a rapid increase in the use of digital technology in healthcare, it is critical the technologies are implemented in a careful and safe way, particularly in the area of mental healthcare.While digital technology provides some benefits for mental ...
Source: Australian Health Information Technology - September 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Loneliness May Increase Dementia Risk, Heart Attacks and Stroke
A study published in the Journal of Neurology Neurosurgery & Psychiatry has found that people who feel lonely are significantly more at risk for developing dementia. The study, headed by Tjalling Jan Holwerda of the VU University Medical Center in Amsterdam, found that participants who reported feeling lonely, no matter how many friends and family surrounded them, were more likely to experience dementia than those who didn't feel lonely. The team focused on approximately 2,200 older adults living in Amsterdam, ages 65 to 86. None of the participants exhibited signs of dementia and none of them lived in f...
Source: Minding Our Elders - September 28, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Amyloid- β in the View of Alzheimer's as a Condition Driven by Persistent Infection
Amyloid-β is an anti-microbial peptide, a part of the innate immune system's attempt to disrupt the activities of infectious pathogens. Some data suggests that Alzheimer's disease, characterized in its early and preclinical stages by slow aggregation of misfolded amyloid-β in ever larger amounts, is driven by persistent infection. It is by no means certain that this is the case, but it does place the aggregation of amyloid-β in a somewhat different light than was originally the case, when it was thought of as molecular waste and little more. Given that amyloid-β is performing a useful function, reducing or elimi...
Source: Fight Aging! - September 27, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Warning Signs That You are Not in Control of Your Life  
Losing control and no longer feeling like we are in any position of power regarding our lives is terrifying, yet common. Sometimes we feel like we are simply bystanders, getting carried away by the  overwhelming circumstances that constantly leave us powerless.   We might feel like everything else is controlling us, whether it’s a job, a relationship, or a friend. How do  we gain our sense of control back?  Being in control of our own life, means being in charge of the aspects of it. Obviously, we cannot be  ahead of everything.   We can only change how we react, how we th...
Source: PickTheBrain | Motivation and Self Improvement - September 27, 2022 Category: Consumer Health News Authors: layan Tags: career confidence featured motivation philosophy productivity tips self-improvement success control Source Type: blogs

The Top 2 Neuropsychiatric Symptoms Of Long COVID (M)
A quarter of people with long COVID met the criteria for depression. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - September 26, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: COVID19 Mental Health subscribers-only Source Type: blogs

Headspace Health ’s Leslie Witt on the future of mental health: Meditation, text-based coaching, teletherapy, telepsychiatry, and community
Q&A: How Headspace Health’s acquisitions alter its mental health product (MobiHealthNews): Headspace Health has revealed two acquisitions this year, the latest coming earlier this month when the digital mental health company announced the purchase of mental wellness app Shine. In a crowded field of mental health startups, the company is using acquisitions to augment its product and add new capabilities … Headspace Health also scooped up Sayana, maker of AI-enabled mental health-tracking and sleep apps. And Headspace itself is the result of a merger between meditation app Headspace and virtual mental healthcare comp...
Source: SharpBrains - September 26, 2022 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation acute anxiety acute depression digital mental health Ginger Headspace Headspace Health meditation app Sayana Shine Source Type: blogs

Weekly Australian Health IT Links – 26 September, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----I have to say the first article calls into question just how the Feds have been procuring IT and what implications there are for Federal Digital Health – a worry!Otherwise a few other good ones as well!-----
Source: Australian Health Information Technology - September 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs