Could nutrition status predict fatigue one week before in patients with nasopharynx cancer undergoing radiotherapy?
CONCLUSIONS: The PG-SGA may be a more accurate predictor of future-week fatigue than individual body composition indicators, particularly when HADS is controlled for as a time-dependent confounder.PMID:38659395 | DOI:10.1002/cam4.7191 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Jihong Song Xinru Yang Jieling Wu Zilan Wu Litao Zhuo Jinsheng Hong Li Su Wenlong Lyu Jinru Ye Yan Fang Zhiying Zhan Hairong Zhang Xiaomei Li Source Type: research

Could nutrition status predict fatigue one week before in patients with nasopharynx cancer undergoing radiotherapy?
ConclusionsThe PG-SGA may be a more accurate predictor of future-week fatigue than individual body composition indicators, particularly when HADS is controlled for as a time-dependent confounder. (Source: Cancer Medicine)
Source: Cancer Medicine - April 25, 2024 Category: Cancer & Oncology Authors: Jihong Song, Xinru Yang, Jieling Wu, Zilan Wu, Litao Zhuo, Jinsheng Hong, Li Su, Wenlong Lyu, Jinru Ye, Yan Fang, Zhiying Zhan, Hairong Zhang, Xiaomei Li Tags: RESEARCH ARTICLE Source Type: research

Viruses, Vol. 16, Pages 669: Identification of HLA-A*11:01 and A*02:01-Restricted EBV Peptides Using HLA Peptidomics
Xiaofei Zhang Miao Xu Epstein-Barr Virus (EBV) is closely linked to nasopharyngeal carcinoma (NPC), notably prevalent in southern China. Although type II latency of EBV plays a crucial role in the development of NPC, some lytic genes and intermittent reactivation are also critical for viral propagation and tumor progression. Since T cell-mediated immunity is effective in targeted killing of EBV-positive cells, it is important to identify EBV-derived peptides presented by highly prevalent human leukocyte antigen class I (HLA-I) molecules throughout the EBV life cycle. Here, we constructed an EBV-positive NPC cell mo...
Source: Viruses - April 25, 2024 Category: Virology Authors: Yufei Wang Wanlin Zhang Ruona Shi Yanran Luo Zhenhuan Feng Yanhong Chen Qiuting Zhang Yan Zhou Jingtong Liang Xiaoping Ye Qisheng Feng Xiaofei Zhang Miao Xu Tags: Article Source Type: research

PICK1 inhibits the malignancy of nasopharyngeal carcinoma and serves as a novel prognostic marker
Cell Death & Disease, Published online: 25 April 2024; doi:10.1038/s41419-024-06687-6PICK1 inhibits the malignancy of nasopharyngeal carcinoma and serves as a novel prognostic marker (Source: Cell death and disease)
Source: Cell death and disease - April 25, 2024 Category: Internal Medicine Authors: Xiaomin Ou Yingzi Zhang Yiqing Xu Yi Liu Wenzhi Tu Chaosu Hu Yong Liu Source Type: research

LINC00313 suppresses autophagy and promotes stemness of nasopharyngeal carcinoma cells through PTBP1/ STIM1 axis
This study investigated the effects and mechanism of LINC00313 in nasopharyngeal carcinoma. It was found that LINC00313 was increased in NPC tissues and cells. LINC00313 knockdown enhanced autophagy, and decreased stemness and cell viability of NPC cells through regulating STIM1. Besides, METTL3/IGF2BP1-mediated m6A modification promoted the stabilization and up-regulation of LINC00313. LINC00313 activated AKT/mTOR pathway in NPC cells through PTBP1/STIM1 axis. All the results demonstrated that upregulation of LINC00313 suppressed autophagy and promoted stemness of NPC cells through PTBP1/STIM1 axis. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - April 25, 2024 Category: Radiology Authors: Lina Xu, Sile Liu, Yang Yang, Lu Shu, Yi Sun Tags: Original Article Source Type: research

HeLa cells cross-contaminated nasopharyngeal carcinoma cell lines: Still a common problem
British Journal of Cancer, Published online: 25 April 2024; doi:10.1038/s41416-024-02675-xHeLa cells cross-contaminated nasopharyngeal carcinoma cell lines: Still a common problem (Source: British Journal of Cancer)
Source: British Journal of Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Anna Makowska Udo Kontny Ralf Weiskirchen Source Type: research

Evaluation of different body temperature measurement methods for patients in the intraoperative period
CONCLUSION: the data from the current study do not recommend using infrared temporal thermometers as a strategy for measuring the body temperature of patients undergoing anesthetic-surgical procedures. Central cutaneous thermometers and esophageal/nasopharyngeal thermometers are equivalent for detecting intraoperative hypothermia.PMID:38655937 | DOI:10.1590/1518-8345.6873.4143 (Source: Revista Latino-Americana de Enfermagem)
Source: Revista Latino-Americana de Enfermagem - April 24, 2024 Category: Nursing Authors: Ariane Souza do Nascimento Cassiane de Santana Lemos Fernanda Baratojo Biachi Fernanda Ribeiro Silva de Lyra Juliana Rizzo Gnatta Vanessa de Brito Poveda Source Type: research

Retraction: Role of SDF-1 α/CXCR4 signaling pathway in clinicopathological features and prognosis of patients with nasopharyngeal carcinoma
Biosci Rep. 2024 Apr 24;44(4):BSR-2017-0144_RET. doi: 10.1042/BSR-2017-0144_RET.NO ABSTRACTPMID:38655838 | DOI:10.1042/BSR-2017-0144_RET (Source: Bioscience Reports)
Source: Bioscience Reports - April 24, 2024 Category: Biomedical Science Source Type: research

Efficacy of metastatic lesion radiotherapy in patients with metastatic nasopharyngeal carcinoma: A multicenter retrospective study
Nasopharyngeal carcinoma (NPC) is prevalent in southern China and exhibits a significant propensity for distant metastasis [1]. The incidence of distant metastasis in NPC ranges from 10  % to 30 % [2–4], and the prognosis for patients with metastatic nasopharyngeal carcinoma (mNPC) is generally unfavorable [5]. Considering the intricate nature of mNPC, comprehensive multidisciplinary treatment approaches are required. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - April 24, 2024 Category: Radiology Authors: Yang Liu, Jie Ma, Xiao-Yi Zeng, Zhi-Chao Zuo, Rui-Zhong Chen, Xiao-Yu Li, Zhong-Guo Liang, Kai-Hua Chen, Xin-Bin Pan, Su Pei, Bin-Bin Yu, Ling Li, Song Qu, Yun-Li Yang, Xiao-Dong Zhu Tags: Original Article Source Type: research

Prediction of severe radiation-induced oral mucositis in locally advanced nasopharyngeal carcinoma using the combined systemic immune-inflammatory index and prognostic nutritional index
ConclusionThe SII –PNI score is a reliable and convenient indicator for predicting sRIOM in patients with LANPC. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research

Lactoferrin mediates epithelial-mesenchymal transformation by regulating the PI3K/AKT/mTOR pathway to inhibit nasopharyngeal carcinoma metastasis
This study suggests that LTF is a potential biomarker of NPC and that LTF-mediated EMT progression plays a tumor-suppressive role in the progression of NPC metastasis.PMID:38650146 | DOI:10.14715/cmb/2024.70.3.19 (Source: Cellular and Molecular Biology)
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Min Xu Ye Fan Guoying Zou Qi Yang Fei Xu Source Type: research

Lactoferrin mediates epithelial-mesenchymal transformation by regulating the PI3K/AKT/mTOR pathway to inhibit nasopharyngeal carcinoma metastasis
This study suggests that LTF is a potential biomarker of NPC and that LTF-mediated EMT progression plays a tumor-suppressive role in the progression of NPC metastasis.PMID:38650146 | DOI:10.14715/cmb/2024.70.3.19 (Source: Mol Biol Cell)
Source: Mol Biol Cell - April 23, 2024 Category: Molecular Biology Authors: Min Xu Ye Fan Guoying Zou Qi Yang Fei Xu Source Type: research

Lactoferrin mediates epithelial-mesenchymal transformation by regulating the PI3K/AKT/mTOR pathway to inhibit nasopharyngeal carcinoma metastasis
This study suggests that LTF is a potential biomarker of NPC and that LTF-mediated EMT progression plays a tumor-suppressive role in the progression of NPC metastasis.PMID:38650146 | DOI:10.14715/cmb/2024.70.3.19 (Source: Cellular and Molecular Biology)
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Min Xu Ye Fan Guoying Zou Qi Yang Fei Xu Source Type: research

CircCDYL2 bolsters radiotherapy resistance in nasopharyngeal carcinoma by promoting RAD51 translation initiation for enhanced homologous recombination repair
Radiation therapy stands to be one of the primary approaches in the clinical treatment of malignant tumors. Nasopharyngeal Carcinoma, a malignancy predominantly treated with radiation therapy, provides an inva... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - April 23, 2024 Category: Cancer & Oncology Authors: Hongke Qu, Yumin Wang, Qijia Yan, Chunmei Fan, Xiangyan Zhang, Dan Wang, Can Guo, Pan Chen, Lei Shi, Qianjin Liao, Ming Zhou, Fuyan Wang, Zhaoyang Zeng, Bo Xiang and Wei Xiong Tags: Research Source Type: research

Correction: Predictive progression outcomes and risk stratification in patients with recurrent or metastatic nasopharyngeal carcinoma who received first ‑line immunochemotherapy
(Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - April 22, 2024 Category: Cancer & Oncology Source Type: research