Extranodal natural killer/T cell lymphoma nasal type simulating osteoradionecrosis with metachronic B lymphoma in the pelvis: Case report
Indian J Pathol Microbiol. 2024 Jan-Mar;67(1):162-165. doi: 10.4103/ijpm.ijpm_296_22.ABSTRACTExtranodal Natural Killer/T Cell Lymphoma Nasal Type (EN-NK/T-CL-NT) is a non-Hodgkin extranodal lymphoma of unfavorable prognosis due to its aggressive nature. This neoplasm mainly affects the paranasal sinuses, nasopharynx, oropharynx, oral cavity, palate, and rarely intestinal, gastric and skin regions. 50-year-old female with a history of lymphoma in nasal and pelvic region. At four years of tumors-free, has facial asymmetry, accompanied by sub-palpebral, nasal and lip edema. Intraoral examination revealed a large ulceration su...
Source: Indian Journal of Pathology and Microbiology - February 15, 2024 Category: Pathology Authors: Frida S Col ín-Guadarrama Violeta E Flores-Solano Argelia Berenice-Rodr íguez V íctor H Toral-Rizo Source Type: research
CPNE1, A Potential Therapeutic Target in Nasopharyngeal Carcinoma, Affects Cell Growth and Radiation Resistance
In conclusion, these results demonstrated that CPNE1 expression is elevated in nasopharyngeal carcinoma cells, and its silencing could attenuate nasopharyngeal carcinoma advancement and improve radiosensitivity to radiation therapy by controlling Akt activation.PMID:38355101 | DOI:10.1667/RADE-23-00220.1 (Source: Radiation Research)
Source: Radiation Research - February 14, 2024 Category: Physics Authors: Shujuan Zhu Rui Li Kun Yin Liming Wu Source Type: research
CPNE1, A Potential Therapeutic Target in Nasopharyngeal Carcinoma, Affects Cell Growth and Radiation Resistance
In conclusion, these results demonstrated that CPNE1 expression is elevated in nasopharyngeal carcinoma cells, and its silencing could attenuate nasopharyngeal carcinoma advancement and improve radiosensitivity to radiation therapy by controlling Akt activation.PMID:38355101 | DOI:10.1667/RADE-23-00220.1 (Source: Radiation Research)
Source: Radiation Research - February 14, 2024 Category: Physics Authors: Shujuan Zhu Rui Li Kun Yin Liming Wu Source Type: research
CPNE1, A Potential Therapeutic Target in Nasopharyngeal Carcinoma, Affects Cell Growth and Radiation Resistance
In conclusion, these results demonstrated that CPNE1 expression is elevated in nasopharyngeal carcinoma cells, and its silencing could attenuate nasopharyngeal carcinoma advancement and improve radiosensitivity to radiation therapy by controlling Akt activation.PMID:38355101 | DOI:10.1667/RADE-23-00220.1 (Source: Radiation Research)
Source: Radiation Research - February 14, 2024 Category: Physics Authors: Shujuan Zhu Rui Li Kun Yin Liming Wu Source Type: research
CPNE1, A Potential Therapeutic Target in Nasopharyngeal Carcinoma, Affects Cell Growth and Radiation Resistance
In conclusion, these results demonstrated that CPNE1 expression is elevated in nasopharyngeal carcinoma cells, and its silencing could attenuate nasopharyngeal carcinoma advancement and improve radiosensitivity to radiation therapy by controlling Akt activation.PMID:38355101 | DOI:10.1667/RADE-23-00220.1 (Source: Radiation Research)
Source: Radiation Research - February 14, 2024 Category: Physics Authors: Shujuan Zhu Rui Li Kun Yin Liming Wu Source Type: research
The application value of LAVA-flex sequences in enhanced MRI scans of nasopharyngeal carcinoma: comparison with T1WI-IDEAL
DiscussionLAVA-Flex sequence provides satisfactory image quality and better visualization of nerves and vessels for NPC with shorter scanning times. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - February 14, 2024 Category: Cancer & Oncology Source Type: research
The individualized delineation of clinical target volume for primary nasopharyngeal carcinoma based on invasion risk of substructures: a prospective, real-word study with a large population
Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in Southeast Asia, exhibiting a significantly uneven geographic distribution [1]. Radiotherapy is the backbone of treatment for NPC due to its inherent radiosensitivity and the intricate anatomic location of the tumor. Intensity modulated radiotherapy (IMRT) can deliver conformal and homogeneous dose distribution to the target area while spare surrounding normal tissue at the same time [2 –4]. A growing body of evidence has demonstrated the efficacy of IMRT in enhancing tumor local control rates and minimizing radiation-induced side effects, making it ...
Source: Radiotherapy and Oncology - February 14, 2024 Category: Radiology Authors: Xiaohui Wang, Nan Huang, Pui Lam Yip, Jing Wang, Runda Huang, Zhuang Sun, Dehua Kang, Qian He, Xiaowu Deng, Chong Zhao, Melvin L.K. Chua, Fei Han Tags: Original Article Source Type: research
Anatomical studies and early results on endoscopic transoral medial pterygomandibular fold approach to salvage retropharyngeal lymphadenectomy in nasopharyngeal carcinoma
CONCLUSION: The endoscopic transoral medial pterygomandibular fold approach is safe and efficient for retropharyngeal lymphadenectomy.PMID:38348656 | DOI:10.1017/S0022215123002013 (Source: Journal of Laryngology and Otology)
Source: Journal of Laryngology and Otology - February 13, 2024 Category: ENT & OMF Authors: Kai Xue Juan Liu Qiang Liu Huan-Kang Zhang Quan Liu Jing Li Xiao-Wen Jiang Ke-Qing Zhao Ye Gu Xiao-Le Song Xi-Cai Sun Hong-Meng Yu Source Type: research
Optimizing cervical target volume in patients with nasopharyngeal cancer based on nodal drainage distance
CONCLUSIONS: In NPC, the maximum LN drainage distance was 3.95 cm without considering the direction. Specifically, in cranial-to-caudal direction, the sufficient vertical drainage distance was 2.81 cm, indicating that a 3-cm extension from the most inferior node may be rational as caudal border of the prophylactic clinical target volume (CTV). These findings promote in-depth understanding of nodal spreading patterns, uncovering paramount evidence for individualized CTV.PMID:38349999 | DOI:10.1158/1078-0432.CCR-23-3274 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - February 13, 2024 Category: Cancer & Oncology Authors: Yang Liu Wenbin Yan Chaosu Hu Xiaodong Huang Kai Wang Yuan Qu Xuesong Chen Runye Wu Ye Zhang Jianghu Zhang Jingwei Luo Ye-Xiong Li Jingbo Wang Junlin Yi Source Type: research
Multimodality radiomics for tumor prognosis in nasopharyngeal carcinoma
by Sararas Khongwirotphan, Sornjarod Oonsiri, Sarin Kitpanit, Anussara Prayongrat, Danita Kannarunimit, Chakkapong Chakkabat, Chawalit Lertbutsayanukul, Sira Sriswasdi, Yothin Rakvongthai
BackgroundThe prognosis of nasopharyngeal carcinoma (NPC) is challenging due to late-stage identification and frequently undetectable Epstein-Barr virus (EBV) DNA. Incorporating radiomic features, which quantify tumor characteristics from imaging, may enhance prognosis assessment. PurposeTo investigate the predictive power of radiomic features on overall survival (OS), progression-free survival (PFS), and distant metastasis-free survival ...
Source: PLoS One - February 12, 2024 Category: Biomedical Science Authors: Sararas Khongwirotphan Source Type: research
IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis
Nasopharyngeal carcinoma (NPC) poses a significant health burden in specific regions of Asia, and some of NPC patients have bone metastases at the time of initial diagnosis. Bone metastasis can cause pathologi... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - February 12, 2024 Category: Cancer & Oncology Authors: Kaifan Yang, Yanjun Hu, Yuanyuan Feng, Kaiqun Li, Ziyan Zhu, Shuyi Liu, Yanling Lin and Bin Yu Tags: Research Source Type: research
Multi-domain neurocognitive impairment following definitive intensity-modulated radiotherapy for nasopharyngeal cancer: a cross-sectional study
CONCLUSIONS: Neurocognitive impairment is prevalent and profound in post-IMRT NPC survivors. Cognitive assessment and rehabilitation should be considered part of survivorship care.PMID:38341098 | DOI:10.1016/j.radonc.2024.110143 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 10, 2024 Category: Radiology Authors: James C H Chow Jack Lee Maria M P Lai Sara Li Adelina M C Lau Beni S Y Ng Gigi G G Leung Sharon T Y Li Jeffrey C F Lui K M Cheung K H Au K H Wong Alexander Y L Lau Benny C Y Zee Source Type: research
Imaging spectrum and complications of otogenic infections: insights into delayed diagnosis
Br J Radiol. 2024 Jan 13:tqae015. doi: 10.1093/bjr/tqae015. Online ahead of print.ABSTRACTSkull base osteomyelitis (SBO) is a late manifestation of complicated otogenic infections that presents a diagnostic challenge. Delayed or missed diagnoses lead to high morbidity and mortality and can be attributed to non-specific symptoms, subtle early radiologic findings, radiologic mimicry of nasopharyngeal carcinoma (NPC), and under-recognition from clinician and radiologists. This pictorial review aims to emphasize on early imaging recognition and distinction between SBO and NPC.PMID:38335140 | DOI:10.1093/bjr/tqae015 (Source: Th...
Source: The British Journal of Radiology - February 9, 2024 Category: Radiology Authors: Eugene Sean Lo Hoi Ming Kwok Nin Yuan Pan Source Type: research
[Retracted] Long non ‑coding RNA KCNQ1OT1 promotes nasopharyngeal carcinoma cell cisplatin resistance via the miR‑454/USP47 axis
Int J Mol Med. 2024 Apr;53(4):31. doi: 10.3892/ijmm.2024.5355. Epub 2024 Feb 9.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the colony formation assay data shown in Figs. 4C and 6D and the Transwell migration and invasion assay data shown in Figs. 4D, 6E and 6F were strikingly similar to data appearing in different form in other research articles written by different authors at different research institutes that had either already been published, or were submitted for publication at around the same time. Owing to the fact that contentious data in the abo...
Source: International Journal of Molecular Medicine - February 9, 2024 Category: Molecular Biology Authors: Feng Yuan Zhiping Lou Zhifeng Zhou Xiaojun Yan Source Type: research
[Retracted] Long non ‑coding RNA KCNQ1OT1 promotes nasopharyngeal carcinoma cell cisplatin resistance via the miR‑454/USP47 axis
Int J Mol Med. 2024 Apr;53(4):31. doi: 10.3892/ijmm.2024.5355. Epub 2024 Feb 9.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the colony formation assay data shown in Figs. 4C and 6D and the Transwell migration and invasion assay data shown in Figs. 4D, 6E and 6F were strikingly similar to data appearing in different form in other research articles written by different authors at different research institutes that had either already been published, or were submitted for publication at around the same time. Owing to the fact that contentious data in the abo...
Source: International Journal of Molecular Medicine - February 9, 2024 Category: Molecular Biology Authors: Feng Yuan Zhiping Lou Zhifeng Zhou Xiaojun Yan Source Type: research
