CC Grand Rounds: 1) Developing Multifaceted Cancer Trials: Integrating Laboratory and Clinical Research and 2) Beyond CD19: What is Next for CAR T Cell Therapy in Acute Lymphoblastic Leukemia (ALL)
CC Grand Rounds: 1) Developing Multifaceted Cancer Trials: Integrating Laboratory and Clinical Research and 2) Beyond CD19: What is Next for CAR T Cell Therapy in Acute Lymphoblastic Leukemia (ALL)For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 3/29/2017 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 28, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Getting to an Effective HIV Vaccine: Perspectives on Progress
James C. Hill Memorial Lecture
Virologist and vaccine expert Dr. Lawrence Corey will deliver the 2017 James C. Hill Memorial Lecture. His talk, titled “ Getting to an Effective HIV Vaccine: Perspectives on Progress, ” will review the state of HIV vaccine development and describe current strategies to advance the field.
Since 1999, Corey has served as principal investigator of the NIAID-supported HIV Vaccine Trials Network (HVTN), which is dedicated to accelerating development of a safe and effective preventive HIV vaccine. The HVTN has built an international scientific collaboration of investigators in 12 countries on ...
Source: Videocast - All Events - February 27, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Aire: new tricks from an old dog
Immunology Interest Group Seminar Series
Aire is a transcriptional regulator that controls immunological tolerance. Its primary modus operandi is the induction – specifically in thymic medullary epithelial cells – of a battery of transcripts encoding proteins characteristic of terminally differentiated peripheral cell-types, and consequently negative selection of T cells that recognize these proteins. After briefly reviewing the classical findings, this presentation will focus on more recently discovered facets of Aire function, including positive selection of a perinatal population of regulatory T cells, inhibition of...
Source: Videocast - All Events - February 22, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Shared Pathways Controlling the Development of Innate and Innate-Like Lymphocytes
Immunology Interest Group Seminar Series
I will present our current understanding of the PLZF-driven molecular mechanisms underlying the development of Innate and Innate-Like Lymphocytes, highlighting recent findings regarding the upstream events leading to PLZF induction and the downsteeam targets of PLZF. Ultimately, these findings shed light on a fundamental dichotomy between conventional lymphocytes, which acquire effector function after encounter with pathogens, and innate lymphocytes which acquire their effector programs during development.
Dr Bendelac obtained his MD and PhD in Paris, France and joined Ronald Schwar...
Source: Videocast - All Events - February 22, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Dissection of the neuronal circuits and synapses that mediate the effects of drugs of abuse
Director's Seminar Series
Research in the laboratory headed by Dr. Alvarez is aimed at identifying the neuronal circuits that mediate and regulate reward-motivated and compulsive behaviors. The laboratory has focused on the behaviors toward substance of abuse, such as cocaine and ethanol, in addition to consummatory behaviors towards natural rewards like food and water. Dr. Alvarez pursues an integrative approach that includes the use of electrophysiology, 2-photon laser scanning microscopy and fast-scanning cyclic voltammetry for dopamine detection together with behavioral testing and in vivo manipulation of circuit activ...
Source: Videocast - All Events - February 21, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
