Influenza Pathogenesis and Therapeutics in Vulnerable Populations
Established in 1950 in honor of former NIH Director Rolla E. Dyer, M.D., a noted authority on infectious diseases, this lectureship, now part of the Wednesday Afternoon Lecture Series, features internationally renowned researchers who have contributed substantially to medical as well as biological knowledge of infectious diseases. The Dyer Lecture is the oldest continuous lecture series at the NIH. Stacey Schultz-Cherry, PhD, is a Full Member and Professor in the Department of Infectious Diseases at St Jude Children ’ s Research Hospital in Memphis, TN as well as Senior Associate Dean for the St Jude Graduate School of...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Sleuthing the Microbiome Reveals Undercover Agents of Oncogenesis
The annual Astute Clinician Lecture was established in 1998 through a gift from the late Dr. Robert W. Miller and his wife, Haruko. It honors U.S. scientists who have observed unusual clinical occurrences and, by investigating them, have opened an important new avenue of research. The lectureship exemplifies how astute clinical observations can lead to innovative research. Speakers are proposed by members of the Medical Executive Committee (MEC) with voting for the top three candidates. Selection from this slate of candidates is made by the NIH Director. An expert in foodborne and intestinal infections, Cynthia Sears is ...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

WALS Lecture- William E. Paul Lecture by Diane Mathis
Dr. Mathis obtained a PhD from the University of Rochester, and performed postdoctoral studies at the Laboratoire de G é n é tique Mol é culaire des Eucaryotes in Strasbourg, France and at Stanford University Medical Center. She returned to Strasbourg at the end of 1983, establishing a laboratory at the LGME [later the Institut de Genetique et de Biologie Moleculare et Cellulaire (IGBMC)] in conjunction with Dr. Christophe Benoist. The lab moved to the Joslin Diabetes Center, Boston in 1999. Through 2008, Dr. Mathis was a Professor of Medicine at Brigham and Women ’ s Hospital and Harvard Medical School, and Associate...
Source: Videocast - All Events - July 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Array of hollow microparticles
An array of hollow microparticles developed in a laboratory for timed-release drug delivery. These particles, which are loaded with colored dye, are small enough to fit through a standard hypodermic needle and designed to biodegrade over time, releasing their drug payload weeks or even months after ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - July 14, 2023 Category: Science Source Type: video

NIH Director's Seminar Series: Molecular regulation of synaptic inhibition
The vast majority of fast inhibitory transmission in the brain is mediated by GABA acting on GABAA receptors (GABAARs), which provides inhibitory balance to excitatory drive and controls neuronal output. Dysregulations of GABAARs and inhibitory synapses have been implicated in a variety of brain disorders, such as epilepsy, anxiety and depression. Pharmacological intervention for these disorders relies on several drug classes that target GABAARs, such as benzodiazepines and neurosteroids. The goal of Lu laboratory is to understand the molecular and cellular mechanisms underlying the regulation of GABAARs and inhibitory syn...
Source: Videocast - All Events - July 7, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Frederick National Laboratory Advisory Committee (FNLAC) - July 2023
The 13th Virtual Meeting of the Frederick National Laboratory Advisory CommitteeAir date: 7/10/2023 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - June 26, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds: Immune Checkpoint Inhibitor Therapy and the Gut Microbiome: A Complex Relationship with Significant Implications in Cancer Treatment
CCR Grand Rounds “ Immune Checkpoint Inhibitor Therapy and the Gut Microbiome: A Complex Relationship with Significant Implications in Cancer Treatment ” Amiran K. Dzutsev, M.D., Ph.D. Staff Scientist Laboratory of Integrative Cancer Immunology Center for Cancer Research, NCI Friday, June 23, 2023 12:00 – 1:00 p.m. Lipsett Amphitheater The Center for Cancer Research Grand Rounds provides a weekly series of lectures that discuss the most up-to-date research regarding new detection methods and treatment modalities and their potential applications. These lectures are designed to enhance professional effectivenes...
Source: Videocast - All Events - June 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds: Organoids and Cell Polarity Proteins in Translational and Mechanistic Cancer Research
CCR Grand Rounds “ Organoids and Cell Polarity Proteins in Translational and Mechanistic Cancer Research ” Senthil K. Muthuswamy, Ph.D. Chief Laboratory of Cancer Biology and Genetics Center for Cancer Research, NCI Senthil K. Muthuswamy, Ph.D., is an eminent cancer biologist who pioneered the development and use of three-dimensional (3D) organoid culture and co-culture methods for mechanistic, tran slational and co-clinical studies. Research from his laboratory helped define the role cell polarity proteins play in cancer biology and therapy resistance.Air date: 6/9/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - June 8, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - CD3z ITAMs mediate TCR ligand discrimination
Dr Guillaume Gaud is the IIG ’ s selected trainee for the 2022-2023 seminar series. Dr. Gaud completed his PhD in molecular oncology at the University of Tours before joining the laboratory of Dr. Saoudi at Inserm where he described the role of CD226 signaling in the amplification of CD4+ T-cell TCR signaling. As a Research Fellow in the laboratory of Paul Love at NICHD, Dr. Gaud has continued to research constituents of the TCR signaling complex. Dr. Gaud has recently demonstrated that T cells expressing TCRs containing inactivated (non-signaling) CD3z ITAMs (6F-CD3z) lose their ability to discriminate between low and h...
Source: Videocast - All Events - June 5, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Reusable nanoparticle-coated sponge removes heavy metals from water
In a laboratory at Northwestern University, NSF-supported researchers have created a nanomaterial coating that can allow a commercially available sponge to be used for removing heavy metals from contaminated water.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 1, 2023 Category: Science Source Type: video

Solar flares produce intense bursts of electromagnetic radiation, which researchers have recreated.
In a laboratory at Caltech, NSF supported researchers have recreated the intense bursts of electromagnetic radiation that occur when the sun produces a solar flare, revealing origins of these plasma loops.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 24, 2023 Category: Science Source Type: video

IIG Seminar - Heterologous Immunity: How Infection History affects Inflammatory Diseases
Our understanding of host-pathogen interaction is primarily derived from studying how the immune system protects us from a single pathogen. In contrast, it is largely unknown how this response alters the body ’ s ability to respond to a second infectious agent or the susceptibility to autoimmunity or cancer. Nicole Joller and her group investigate the long-term effects of pathogenic challenges on future responses. Currently, they are focusing on changes in the regulatory compartment of the adaptive immune system. The Joller laboratory employs in-vivo animal models, cellular assays and genome-scale approaches to investiga...
Source: Videocast - All Events - May 9, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - Multimodal decoding of liver regeneration and repair
Neil Henderson, Professor of Tissue Repair and Regeneration at the University of Edinburgh, is an academic hepatologist with an international profile in defining cellular interactions and molecular pathways driving organ fibrosis. Organ fibrosis (scarring) is a major cause of morbidity and mortality worldwide, and as yet there are no effective anti-fibrotic treatments. Dr. Henderson is primarily interested in the cellular and molecular mechanisms that drive organ fibrosis, and the pathways which are responsible for efficient wound healing and healthy tissue regeneration following injury. Dr. Henderson and his group have de...
Source: Videocast - All Events - May 9, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Clinical Center Grand Rounds: Exploring the link between Sickle Cell, α -Thalassemia, P Falciparum Malaria and Burkitt Lymphoma in Africa
Sam Mbulaiteye, MBChB, M.Phil., M.Med. Senior Investigator Infections and Immunoepidemiology Branch Division of Cancer Epidemiology and Genetics (DCEG) National Cancer Institute, NCI and Swee Lay Thein, B.S., F.R.C.P., F.R.C.Path., D.Sc., FMedSci Chief, Laboratory of Sickle Cell Genetics and Pathophysiology Chief, Sickle Cell Branch National Heart, Lung, and Blood Institute, NHLBIFor more information go tohttps://clinicalcenter.nih.gov/about/news/grcurrent.htmlAir date: 5/10/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 8, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH Surgery, Radiology and Laboratory Medicine Groundbreaking Event
This groundbreaking event will commemorate the beginning of construction for a new 547,290 square foot addition to the NIH Clinical Center and the renovation of approximately 82,000 square feet of existing space.Air date: 5/16/2023 11:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - April 24, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video