Chemist in the Nagib Laboratory at Ohio State
Researcher Sean Rafferty in the Nagib Laboratory at The Ohio State University, where chemists develop new molecules for drug development.
[Research supported in part by National Science Foundation Faculty Early Career Development (CAREER) award CHE 1654656.]
To learn more about this research, ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - November 18, 2019 Category: Science Source Type: video
Kinyoun Lecture: Structure-Assisted Design of Universal Vaccines and Therapeutics Against Influenza Virus
Kinyoun Lecture
Ian A. Wilson, D. Phil., D.Sc., Hansen professor of structural biology and chair, department of integrative structural and computational biology at The Scripps Research Institute, La Jolla, Calif., will deliver the 2019 Joseph J. Kinyoun Memorial Lecture on Tuesday, November 19, at 3 p.m. in Lipsett Amphitheater, Bldg. 10. His presentation is titled, “ Structure-assisted Design of Universal Vaccines and Therapeutics against Influenza Virus. ”
Wilson will explain how insights gained through structural biology approaches are aiding in devising new ways to treat or prevent influenza. The health and economi...
Source: Videocast - All Events - November 12, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Neuroscience Seminar - Axon Degeneration: Molecular Mechanisms and Therapeutic Potential
NIH Neuroscience Series Seminar
Dr. DiAntonio ’ s laboratory investigates molecular mechanisms that control the structure and function of neural circuits in development and disease. They combine genetic, molecular, neuroanatomical, and electrophysiological studies in both Drosophila and mouse to identify pathways required for the development, maintenance, and regeneration of axons and synapses.
Axonal degeneration is a common feature of many neurological diseases including hereditary neuropathies, diabetes, glaucoma, chemotherapy-induced neurotoxicity, and neurodegenerative diseases such as Alzheimer ’ s and Parkinson ...
Source: Videocast - All Events - November 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Bench to Bedside to Market: FDA Regulation of Medical Devices
OHSRP Education Series
Drs. Bill Prichard and Jonathan Green will be conducting this presentation. Dr. Green is the Director of OHSRP, and Dr. Prichard, a radiologist by training, is a Medical Officer in the Center for Interventional Oncology at the NIH Clinical Center. Prior to his arrival here in 2016, Dr. Prichard was a Medical Officer for 21 years at the FDA ’ s Center for Devices and Radiological Health. He has considerable regulatory expertise including preclinical study design, review of clinical trial and marketing applications, and resolution of post-market regulatory and safety issues for a wide range of medica...
Source: Videocast - All Events - October 29, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Phantoms in the Transcriptome: How Nucleic Acid Modifications Shape Gene Expression in Development and Disease
CCR Grand Rounds
Research in the Oberdoerffer laboratory examines the role of DNA and RNA modifications in determining: 1) how a single gene generates multiple protein-coding variants and 2) how a single messenger RNA (mRNA) molecule dictates distinct protein fates during the process of translation. As the archetype for epigenetic control within DNA, they specifically examine how nucleic acid modifications of cytosine influence gene expression at unexpected stages in the life cycle of an mRNA. Dr. Oberdoerffer and colleagues investigate 5mC and its oxidized derivatives in genic DNA and ask whether elevated detection at exo...
Source: Videocast - All Events - October 28, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Human-Animal Interactions in the Research Environment (Day 1)
This workshop will explore and characterize aspects of the complex scientific, ethical, and occupational health issues associated with human-animal interactions in the biomedical research environment. The workshop will consider the full range of people who are involved in animal care and use in biomedical research settings, including research scientists, their staff and students, laboratory animal facilities managers, animal care staff, veterinarians and members of Institutional Animal Care and Use Committees (IACUCs). This workshop will also consider possible metrics that, in combination with other contextual information,...
Source: Videocast - All Events - October 16, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Human-Animal Interactions in the Research Environment (Day 2)
This workshop will explore and characterize aspects of the complex scientific, ethical, and occupational health issues associated with human-animal interactions in the biomedical research environment. The workshop will consider the full range of people who are involved in animal care and use in biomedical research settings, including research scientists, their staff and students, laboratory animal facilities managers, animal care staff, veterinarians and members of Institutional Animal Care and Use Committees (IACUCs). This workshop will also consider possible metrics that, in combination with other contextual information,...
Source: Videocast - All Events - October 16, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Human-Animal Interactions in the Research Environment
This workshop will explore and characterize aspects of the complex scientific, ethical, and occupational health issues associated with human-animal interactions in the biomedical research environment. The workshop will consider the full range of people who are involved in animal care and use in biomedical research settings, including research scientists, their staff and students, laboratory animal facilities managers, animal care staff, veterinarians and members of Institutional Animal Care and Use Committees (IACUCs). This workshop will also consider possible metrics that, in combination with other contextual information,...
Source: Videocast - All Events - October 15, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Dynamic organelle shape and function during herpesvirus infection
NIH Director's Wednesday Afternoon Lecture Series
Research in the Cristea laboratory focuses on characterizing mechanisms of cellular defense against viruses, as well as mechanisms used by viruses to manipulate these critical cellular processes. Towards these goals, her lab has promoted the integration of virology with proteomics and bioinformatics. The development of methods for studying virus-host protein interactions in space and time during the progression of an infection has allowed her group to bridge developments in mass spectrometry to important findings in virology. For example, her laboratory has contributed to t...
Source: Videocast - All Events - October 10, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Bad deeds go unpunished: the vacuole guard hypothesis and pathogen intracellular growth
NIH Director ’ s Wednesday Afternoon Lecture Series
Ralph Isberg has been a Professor of Molecular Biology and Microbiology at Tufts University School of Medicine for 32 years. After receiving an undergraduate degree at Oberlin College, he obtained his PhD at Harvard working on transposable genetic elements in bacteria. Throughout his career at Tufts he has primarily focused on the pathogenesis of Legionella pneumophila and enteropathogenic Yersinia, and has recently initiated projects on tackling drug resistance in nosocomial organisms. His research highlights include the identification of proteins involved in uptake of...
Source: Videocast - All Events - October 10, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
A 3D representation of the spin-excitation continuum
-- a possible hallmark of a quantum spin liquid -- observed in a single crystal sample of cerium zirconium pyrochlore in experiments at Oak Ridge National Laboratory (ORNL). Inelastic neutron-scattering experiments at ORNLÂs Spallation Neutron ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - October 2, 2019 Category: Science Source Type: video
Evolution of Adaptive Immunity in Vertebrates
NIH Director's Wednesday Afternoon Lecture Series
William E. Paul Lecture
This annual lecture, begun in 2016 and part of the Wednesday Afternoon Lecture Series, honors the legacy of Dr. William E. Paul. Dr. Paul was the leader of the NIH immunology community and his career is without parallel in the field of immunology.
The Cooper laboratory currently studies the evolution of adaptive immunity, primarily in jawless vertebrate models (lampreys and hagfish), and explores the use of lamprey monoclonal antibodies for diagnosis of infectious diseases and cancers in humans.For more information go tohttps://oir.nih.gov/wals/2019-...
Source: Videocast - All Events - October 1, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Frederick National Laboratory Advisory Committee - October 2019
The 17th meeting of the Frederick National Laboratory Advisory CommitteeAir date: 10/24/2019 9:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - September 30, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Behaviors of superconductor with one of world's strongest magnets (Image 1)
An example of a typical device that scientists at Brookhaven National Laboratory use to measure electrical resistivity as a function of temperature and magnetic field. The scientists grew the film via atomic layer-by-layer molecular beam epitaxy, patterned it into a device and wire bonded it to a ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - August 19, 2019 Category: Science Source Type: video
Behaviors of superconductor with one of world's strongest magnets (Image 2)
This composite image offers a glimpse inside the custom-designed molecular beam epitaxy system that Brookhaven National Laboratory physicists use to create single-crystal thin films for studying the properties of superconducting cuprates. [Image 2 of 3 related images. See (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - August 19, 2019 Category: Science Source Type: video
