' Seedling of Thought '
"Seedling of Thought," by Rajashekar Iyer, Martha Gillette Laboratory. Part of the Art of Science program at the Carl R. Woese Institute for Genomic Biology at the University of Illinois (U of I), this delicate structure is a single brain cell (neuron) from a region of the brain called the ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 11, 2018 Category: Science Source Type: video

Faceting ionic shells into icosahedra via electrostatic (Image 1)
These simulated shapes are constructed from dozens of charged, closely packed particles, models that are helping researchers better understand how some viruses are constructed and guiding the design of new materials. The research, from the laboratory of Monica Olvera de la Cruz of Northwestern ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 30, 2018 Category: Science Source Type: video

Faceting ionic shells into icosahedra via electrostatic (Image 2)
These simulated shapes are constructed from dozens of charged, closely packed particles, models that are helping researchers better understand how some viruses are constructed and guiding the design of new materials. The research, from the laboratory of Monica Olvera de la Cruz of Northwestern ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 30, 2018 Category: Science Source Type: video

Regulating Autoimmunity and Autoinflammation: Cytokine blockade and beyond
Immunonology IG Seminar Richard Siegel's interest in immunology and apoptosis began in the late 1980's at the University of Pennsylvania School of Medicine where he was an M.D., Ph.D. student. Working with Mark Greene and John Reed, he studied the influence of bcl-2 on T cell apoptosis and repertoire selection. He trained in Internal Medicine and Rheumatology at Hospital of the University of Pennsylvania, and moved to the NIH in 1996 to do postdoctoral training with Michael Lenardo in the Laboratory of Immunology in the National Institute of Allergy and Infectious Disease. There he studied apoptosis signaling and the molec...
Source: Videocast - All Events - May 29, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Advances in Cancer Prevention Lecture 2018: Successes and Challenges of Vaccines to Prevent HPV-associated Cancers
The Annual Advances in Cancer Prevention Lecture is sponsored by the Cancer Prevention Fellowship Program (CPFP) within the Division of Cancer Prevention (DCP) at NCI. It is also part of the course offerings of the annual NCI Summer Curriculum in Cancer Prevention, but is open to the entire NIH community and general public. This annual lecture addresses current challenges and/or approaches used by investigators to address gaps, advance science, and promote the application of successful strategies in the field of cancer prevention and control. NIH Distinguished Investigator and Deputy Chief of the Laboratory of Cellular Onc...
Source: Videocast - All Events - May 24, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Understanding Molecular Signatures of Aging
The Trans-NIH GeroScience Interest Group (GSIG), cordially invites you to its spring seminar, featuring Dr. GR Scott Budinger. Dr. Budinger is the Chief of Pulmonary and Critical Care in the Department of Medicine at Northwestern University Feinberg School of Medicine and is the Ernest S. Bazley Professor of Airway Diseases and a Professor of Medicine (Pulmonary and Critical Care) and of Cell and Molecular Biology. The Budinger laboratory is interested in understanding how aging biology intersects with the age-related risk of acute and chronic lung diseases. The Budinger lab is testing whether a decline in the function of...
Source: Videocast - All Events - May 24, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Sounding the Alarm and Putting Out the Fire: New Mechanistic Insights into Inflammation Triggered by Invasive Infection
NIH Director ’ s Wednesday Afternoon Lecture Series The Lieberman laboratory studies cytotoxic T lymphocytes and their role in infection and tumor immunity. They study the molecular pathways used by killer lymphocytes and their cytotoxic granule proteases, called granzymes, and pore-forming proteins, perforin and granulysin, to induce programmed cell death. They have defined a caspase-independent programmed cell death pathway activated by granzyme A. Recent work has identified an unexpected role for granzymes and granulysin in protection against bacteria and parasites. They recently uncovered the molecular basis for infl...
Source: Videocast - All Events - May 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Synaptic signaling in cerebellar circuits
NIH Director's Wednesday Afternoon Lecture Series Margaret Pittman Lecture Part of the NIH Director's Wednesday Afternoon Lecture Series, the lecture is given by a researcher dedicated to advancing and improving the careers of women scientists. Since 1994 when this annual lecture began, every speaker has exemplified the intelligence, scientific excellence, and drive that made Margaret Pittman a leader as the first female laboratory chief at NIH. The cerebellum facilitates learned, coordinated movements and corrects errors. Signals to execute these functions are carried out by the large neurons of the cerebellar nuclei, wh...
Source: Videocast - All Events - April 27, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Anita Roberts Lecture: Specializations for decision making in primate prefrontal cortex
Women Scientist Advisors Anita Roberts Lecture Specializations for decision making in primate prefrontal cortex Some of the most sophisticated behaviors of primates, including humans, depend on the granular prefrontal cortex (PFC), yet there are few well defined and experimentally verified functional specializations within the primate PFC, especially at a causal level. Recent work from our laboratory has demonstrated contrasting specializations of the ventrolateral PFC (VLPFC) and the orbital PFC (also known as orbitofrontal cortex, OFC). We found that the OFC and the VLPFC play complementary roles in updating representat...
Source: Videocast - All Events - April 24, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Frederick National Laboratory Advisory Committee (FNLAC) - May 2018
The 14th meeting of the Frederick National Laboratory Advisory CommitteeAir date: 5/8/2018 9:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - April 24, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Annual Advances in Cancer Prevention Lecture 2018
The Annual Advances in Cancer Prevention Lecture is sponsored by the Cancer Prevention Fellowship Program (CPFP) within the Division of Cancer Prevention (DCP) at NCI. It is also part of the course offerings of the annual NCI Summer Curriculum in Cancer Prevention, but is open to the entire NIH community and general public. This annual lecture addresses current challenges and/or approaches used by investigators to address gaps, advance science, and promote the application of successful strategies in the field of cancer prevention and control. NIH Distinguished Investigator and Deputy Chief of the Laboratory of Cellular Onc...
Source: Videocast - All Events - March 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Rapid, genetically tailored N-of-1 neurotherapeutics: a case study in Batten disease
NIH Neuroscience Series Seminar Dr. Yu ’ s laboratory leads genome-wide searches for rare single-gene causes of autism to reveal ASD ’ s underlying genomic architecture, to understand its neurobiological causes, and to illuminate possible treatments. For instance, they are studying whole exome sequencing data from a large cohort of patients recruited via the Autism Sequencing Consortium, and have uncovered a striking enrichment of gene knockouts, especially in girls, and several dozen novel candidate genes, including several of special neurobiological interest responsible for glutamatergic and serotonergic signaling. T...
Source: Videocast - All Events - March 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Analysis of RBC Derived Microparticles from Sickle Cell Mice using Mass Spectrometry: The Impact of Sickle Cell Disease Induced Oxidative Stress on MP Proteome
Proteomics Interest Group Polymerization of sickle cell hemoglobin S (HbS) is recognized as a key event in the pathophysiology of sickle cell disease (SCD). Repeated HbS polymerization promotes an altered red blood cell (RBC) membrane, hemolysis, and microparticles (MP) formation, which have been shown to play a significant role in the interaction of RBCs with vascular endothelium and progression of vaso-occlusive events. We have recently reported that free HbS oxidizes faster, remains locked in a highly oxidizing form (ferryl) longer and loses heme faster than normal HbA. The first part of this seminar will focus on the L...
Source: Videocast - All Events - March 21, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Innate Lymphoid cell (ILC) subsets Controlled by Dynamic Expression of Master Regulators
Immunonology IG Seminar Dr. Jinfang Zhu received his Ph.D. in biochemistry and molecular biology from the Shanghai Institute of Biochemistry, Chinese Academy of Sciences. He completed his postdoctoral training at the Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, with late Dr. William E. Paul, studying CD4 T helper cell differentiation controlled by key transcription factors including GATA3 and T-bet. He started his own group in the Laboratory of Immunology as an Earl Stadtman investigator, and is now the section chief of the Molecular and Cellular Immunoregulation Section in the Laborator...
Source: Videocast - All Events - March 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

From PHD to NPR: Careers in Science Communication and Tips for Communicating Your Research
Ever wondered how to transition from a career in laboratory research to a career in science communication? Or are you happy in the lab, but want to enhance your skills in communicating research to broader audiences? Join us as NPR's Madeline Sofia details her journey from the bench to a career in science communication, and provides practical tips for researchers to enhance their ability to communicate their science. Madeline Sofia is an assistant producer on NPR's Science Desk, specifically for Joe's Big Idea. The goal of Joe's Big Idea is to tell scientific stories that explore the minds and motivations of researchers and...
Source: Videocast - All Events - March 13, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video