A Systematic Review and Meta-Analysis of Metabolic Syndrome
Prevalence in Chinese Inpatients with Bipolar Disorder
Horm Metab Res DOI: 10.1055/a-1882-8423The aim of the work was to study the prevalence of metabolic syndrome in Chinese
patients with bipolar disorder. We searched Chinese literature related to the
study in prevalence of metabolic syndrome in bipolar disorder in Chinese
language, among which results such as comments, letters, reviews and case
reports were excluded. The prevalence of metabolic syndrome in bipolar disorder
was researched and discussed. A total of 1562 subjects were included in 11
studies. The prevalence of MetS in bipolar disorder was 33% (95%
...
Source: Hormone and Metabolic Research - July 20, 2022 Category: Endocrinology Authors: Tao, Hejian Shen, Dong Zhou, Yong Sun, Fengli Li, Guorong Jin, Weidong Tags: Original Article: Endocrine Care Source Type: research
Early Clinical, Biochemical and Radiological Features in Obese and
Non-Obese Young Women with Polycystic Ovarian Syndrome: A Comparative
Study
In conclusion, clinical,
biochemical, and radiological features can be used in the early diagnosis of
PCOS. Obesity is an independent risk factor for PCOS and is associated with an
increased risk of complications. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - July 20, 2022 Category: Endocrinology Authors: Kumar, Naina Agarwal, Himani Tags: Original Article: Endocrine Care Source Type: research
COVID-19 Infections in Gonads: Consequences on
Fertility?
Horm Metab Res DOI: 10.1055/a-1891-6621COVID-19 may influence human fertility and sexuality in several ways. Different
cell types in gonads show a constitutive expression of angiotensin-converting
enzyme 2 (ACE2) and transmembrane protease serine subtype 2 (TMPRSS2), which
provide potential entry pathways for SARS-CoV-2. In addition to the biological
effects of a COVID-19 infection on the gonads, the impact of the ongoing
COVID-19 pandemic on mental health issues and sexual behavior may affect
reproduction. This review summarizes the current knowledge on the influ...
Source: Hormone and Metabolic Research - July 19, 2022 Category: Endocrinology Authors: Bechmann, Nicole Maccio, Umberto Kotb, Reham Dweik, Rania Al Cherfane, Michele Moch, Holger Bornstein, Stefan R. Varga, Zsuzsanna Tags: Review Source Type: research
Insulin-Like Growth Factor-I Might be a Predictor for Severe
Non-Alcoholic Fatty Liver Disease in Morbidly Obese Patients
This study was conducted on 316
morbidly obese patients (250 F/66 M). The data of
patients before and 1st-year after bariatric surgery were recorded. According to
the ultrasonographically NAFLD screening, patients with normal hepatic features
were classified as Group 1(n=57), with mild and moderate NAFLD were
classified as Group 2(n=219), and with severe NAFLD were classified as
Group 3(n=40). IGF-1 standard deviation scores (SDSIGF1) were calculated
according to age and gender. Parameters that could predict the presence and
severity of NAF...
Source: Hormone and Metabolic Research - July 15, 2022 Category: Endocrinology Authors: Turgut, Seda Acarer, Didem Seyit, Hakan Pamuk, Naim Piskinpasa, Hamide Bozkur, Evin Karabulut, Mehmet Cakir, Ilkay Tags: Original Article: Endocrine Care Source Type: research
COVID-19 and Lipid Disorders
Horm Metab Res DOI: 10.1055/a-1860-2610An elevated cholesterol concentration has been suspected to increase the
susceptibility for SARS-COV-2 infection. Cholesterol plays a central role in the
mechanisms of the SARS-COV-2 infection. In contrast, higher HDL-cholesterol
levels seem to be protective. During COVID-19 disease, LDL-cholesterol and
HDL-cholesterol appear to be decreased. On the other hand, triglycerides (also
in different lipoprotein fractions) were elevated. Lipoprotein(a) may increase
during this disease and is most probably responsible for thromboembo...
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Julius, Ulrich Schatz, Ulrike Tselmin, Sergey Morawietz, Henning Tags: Review Source Type: research
Downregulation of lncRNA ASMTL-AS1 in Epithelial Ovarian Cancer
Correlates with Worse Prognosis and Cancer Progression
This study demonstrates a significant
role for lowly expressed ASMTL-AS1 in EOC allowing for the prediction of
prognosis for EOC. Considering that ASMTL-AS1 is strongly involved in cell
growth and invasion, ASMTL-AS1 may be a promising marker for EOC prognosis and
therapy [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Xu, Hui Tang, Yan Liu, Lu Yan, Jie Qin, Li Tags: Original Article: Endocrine Research Source Type: research
Association of the Transcription Factor 7-Like 2 (TCF7L2) rs7903146
Polymorphism with the Risk of Diabetic Nephropathy: A
Meta-Analysis
In conclusion, TCF7L2 rs7903146 polymorphism is associated with
susceptibility to diabetic nephropathy. Allele T and genotype TT can increase
the risk of diabetic nephropathy. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Ning, Bobiao Wang, Jie Li, Baohua Lyu, Cuixia Tags: Original Article: Endocrine Care Source Type: research
The Antiobesity Effect and Safety of GLP-1 Receptor Agonist in
Overweight/Obese Patients Without Diabetes: A Systematic Review and
Meta-Analysis
Horm Metab Res 2022; 54: 458-471 DOI: 10.1055/a-1844-1176Aim To determine the antiobesity effect and safety of glucagon-like
peptide-1 receptor agonist (GLP-1RA) including liraglutide, exenatide and
semaglutide treatment in overweight/obese patients without diabetes. The
random-effect model was used to pool data extracted from included literatures.
The weighted mean difference (WMD), odds ratio and 95% confidence
interval (CI) were used to present the meta-analysis results (PROSPERO
registration number: CRD 42020173199). The sources of intertrial heterogeneity,
...
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Guo, Xiaonan Zhou, Zhibo Lyu, Xiaorui Xu, Hanyuan Zhu, Huijuan Pan, Hui Wang, Linjie Yang, Hongbo Gong, Fengying Tags: Original Article: Endocrine Care Source Type: research
Reduced Bone Mineral Density in Middle-Aged Male Patients with Adult
Growth Hormone Deficiency
Horm Metab Res 2022; 54: 450-457 DOI: 10.1055/a-1850-7461The aim of the work was to investigate the bone mineral density (BMD) in
middle-aged male patients with both childhood-onset (CO) and adulthood-onset
(AO) adult growth hormone deficiency (AGHD). In this retrospective
cross-sectional study in a major medical center in China, dual X-ray
absorptiometry was performed in 50 male AGHD patients (average age was
35.2±9.8 years) and 50 age- and BMI-matched non-athletic healthy men.
BMD was compared between AGHD patients and controls. Compared with healthy
...
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Liu, Shanshan Yang, Hongbo Xu, Hanyuan Zhou, Zhibo Bai, Xi Wang, Linjie Duan, Lian Gong, Fengying Zhu, Huijuan Pan, Hui Tags: Original Article: Endocrine Care Source Type: research
Correlation of Serum Estradiol with Bone Mineral Density and Bone
Metabolism in Patients of Postmenopausal Type 2 Diabetes Mellitus Complicated with
Osteoporosis
This study aims to demonstrate the correlation
between serum estradiol (E2) levels and osteoporosis, bone mineral density, and
bone metabolism indicators in postmenopausal women with T2DM complicated with
osteoporosis (T2DM-OP). 130 postmenopausal women with T2DM were divided into the
T2DM group (n=62) and the T2DM-OP group (n=68) according to bone
mineral density (BMD). In addition, 80 postmenopausal women with average blood
glucose and bone density were selected as the healthy control group. We compare
the serum levels of E2, bone metabolism indicators...
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Yang, Fan Xu, Qiangwei Tags: Original Article: Endocrine Care Source Type: research
Is TSH a Reliable Indicator of Thyroid Hormone Status in
Pregnancy?
In conclusion, TSH levels beyond the
range accepted as normal do not, in most cases, reflect abnormal thyroid hormone
levels during pregnancy. TSH is not a good screen for overt hypothyroidism in
pregnancy. This may be due, at least in the first trimester, to thyrotropic
effects of HCG. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Karavani, Gilad Daoud-Sabag, Lina Chay, Cherut Gillis, David Strich, David Tags: Original Article: Endocrine Care Source Type: research
The Diagnosis of Normocalcaemic Hyperparathyroidism is Strikingly
Dissimilar Using Different Commercial Laboratory Assays
Horm Metab Res 2022; 54: 429-434 DOI: 10.1055/a-1856-4900We assessed the impact of intact parathyroid hormone (iPTH) and adjusted calcium
analyses on Abbott, Roche and Siemens analytical platforms in the diagnosis of
normocalcaemic primary hyperparathyroidism (NCPHPT). These assays are used by
over 85% of clinical laboratories in the UK. Over five months,
consecutive serum samples from outpatients with NCPHPT in the laboratory with
Abbott assays were identified, aliquoted and stored at –80°C.
Frozen aliquots were transported monthly to the other two laboratorie...
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Kalaria, Tejas Fenn, Jonathan Sanders, Anna Yates, Alexandra Duff, Christopher Ashby, Helen Mohammed, Pervaz Ford, Clare Gama, Rousseau Tags: Original Article: Endocrine Care Source Type: research
Endothelial Dysfunction and Platelet Hyperactivation in Diabetic
Complications Induced by Glycemic Variability
Horm Metab Res 2022; 54: 419-428 DOI: 10.1055/a-1880-0978The development and progression of the complications of chronic diabetes mellitus
are attributed not only to increased blood glucose levels but also to glycemic
variability. Therefore, a deeper understanding of the role of glycemic
variability in the development of diabetic complications may provide more
insight into targeted clinical treatment strategies in the future. Previously,
the mechanisms implicated in glycemic variability-induced diabetic complications
have been comprehensively discussed. However, e...
Source: Hormone and Metabolic Research - July 14, 2022 Category: Endocrinology Authors: Huang, Ye Yue, Long Qiu, Jiahuang Gao, Ming Liu, Sijin Wang, Jingshang Tags: Review Source Type: research
Altered Circulating Leptin, hGH, and IGF-I in Prediabetes and
Screening-Diagnosed T2DM Unrelated to Metabolic Syndrome in Women Post
Gestational Diabetes
Horm Metab Res DOI: 10.1055/a-1850-5392Recently, we proposed two pathophysiologic subtypes of type 2 diabetes mellitus
(T2DM), one related and one unrelated to metabolic syndrome. To begin to
understand the pathophysiology of the subtype unrelated to metabolic syndrome,
we now measured selected hormones and signaling molecules in affected
individuals. In this cross-sectional analysis, we examined 138 women out of the
monocenter, post gestational diabetes study PPSDiab. Of these women, 73 had
prediabetes or screening-diagnosed T2DM, 40 related to metabolic syndrome...
Source: Hormone and Metabolic Research - July 12, 2022 Category: Endocrinology Authors: Kern-Matschilles, Stefanie Gar, Christina Schilbach, Katharina Haschka, Stefanie Julia Rauch, Miss Barbara Then, Cornelia Seissler, Jochen Bidlingmaier, Martin Lechner, Andreas Tags: Original Article: Endocrine Care Source Type: research
The Impact of COVID-19 in Bone Metabolism: Basic and Clinical
Aspects
Horm Metab Res DOI: 10.1055/a-1825-9641The use of standard procedures for the diagnosis of osteoporosis and assessment
of fracture risk significantly decreased during the COVID-19 pandemic, while the
incidence of fragility fractures was mostly unaltered. Both COVID-19 per se and
its treatments are associated with a negative impact on bone health. Preclinical
models show that mice infected with SARS-CoV2 even without symptoms display loss
of trabecular bone mass two weeks post infection, due to increased numbers of
osteoclasts. Osteoporosis medications do not aggra...
Source: Hormone and Metabolic Research - June 20, 2022 Category: Endocrinology Authors: Tsourdi, Elena Hofbauer, Lorenz Rauner, Martina Tags: Review Source Type: research
