Geriatric Nutritional Risk Index and the Survival of Patients with Hepatocellular Carcinoma: A Meta-Analysis
In conclusion, malnutrition indicated by a low pretreatment GNRI may be a risk factor of poor survival of patients with HCC. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 29, 2023 Category: Endocrinology Authors: Xu, Xingwen Kang, Fugui Zhang, Nan Niu, Yiming Jia, Jintang Tags: Original Article: Endocrine Care Source Type: research

Adipose Tissue-Derived Stromal/Stem Cells Transplantation with Cholecalciferol Supplementation in Recent-Onset Type 1 Diabetes Patients: Twelve Months Follow-Up
Horm Metab Res DOI: 10.1055/a-2094-1039To evaluate safety and therapeutic effect along 12 months of allogenic adipose tissue-derived stromal/stem cells (ASCs) transplantation with cholecalciferol (VITD) in patients with recent-onset type 1 diabetes (T1D). Prospective, phase II, open trial, pilot study in which patients with recent onset T1D received ASCs (1xKgx106 cells) and VITD 2000UI/day for 12 months (group 1) and were compared to controls with standard insulin therapy (group 2). Adverse events, C-peptide area under the curve (CPAUC), insulin dose, H...
Source: Hormone and Metabolic Research - June 29, 2023 Category: Endocrinology Authors: Dantas, Joana R. Araujo, Debora Batista Silva, Karina Ribeiro Souto, Debora Lopes Pereira, Maria de Fatima Carvalho Raggio, Luiz Ronir Claudio-da Silva, Cesar Couri, Carlos Eduardo Maiolino, Angelo Rebellato, Carmen Lucia Kuniyoshi Daga, Debora Regina Sen Tags: Original Article: Endocrine Care Source Type: research

Knockdown of CENPN Inhibits Glucose Metabolism and Induces G1 Arrest in Esophageal Cancer Cells by Regulating PI3K/AKT Signaling Pathway
Horm Metab Res DOI: 10.1055/a-2084-3112Esophageal carcinoma (ESCA) is a deadly malignancy with an increasing incidence year by year. The purpose of this study was to explore the function of CENPN in ESCA. Based on TCGA public data platform, the transcription level of CENPN in ESCA was analyzed. Subsequently, ESCA cells with CENPN overexpression or knockdown were constructed. The proliferation and migration levels of ESCA cells were evaluated by CCK-8, colony formation assay, and transwell analysis. Western blotting was used to detect protein levels associated with...
Source: Hormone and Metabolic Research - June 13, 2023 Category: Endocrinology Authors: Xu, Shasha Wei, Xing Tags: Original Article: Endocrine Research Source Type: research

Study on the Regulation of Trophoblast Activity by Abnormally Expressed lncRNA CCDC144NL-AS1 in Patients with Gestational Diabetes Mellitus
In conclusion, upregulated CCDC144NL-AS1 served as a diagnostic biomarker of GDM and regulated the development of trophoblast cells via negatively modulating miR-143–3p. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 9, 2023 Category: Endocrinology Authors: Cao, Dan Wang, Yu Tags: Original Article: Endocrine Research Source Type: research

Predictors of Delayed Hyponatraemia After Surgery for Pituitary Tumour
In conclusion, EPDI, intra-operative CSF leak and peri-operative steroid use were significant predictors of DH. EPDI predicts moderate to severe hyponatraemia with 80% specificity but has low sensitivity(47%). As most patients have asymptomatic hyponatraemia, serum sodium measurement on POD 7 to 10 would be helpful to identify DH in patients at increased risk. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 9, 2023 Category: Endocrinology Authors: Rajan, Remya Chacko, Ari George Verma, Shivendra Kapoor, Nitin Paul, Thomas Thomas, Nihal Jebasingh, Felix Cherian, Kripa Elizabeth Sahu, Shalini Shyamasunder, Asha Hesarghatta Tags: Original Article: Endocrine Care Source Type: research

Cardiovascular Outcomes of Differentiated Thyroid Cancer Patients on Long Term TSH Suppression: A Systematic Review and Meta-Analysis
Horm Metab Res 2023; 55: 379-387 DOI: 10.1055/a-2084-3408We performed a systematic review and meta-analysis of the literature regarding cardiovascular outcomes of differentiated thyroid cancer (DTC) patients who are on long term thyroid stimulating hormone suppression. Searches were carried out using Prisma guidelines in Medline, Embase, CENTRAL, CINAHL and Scopus databases. Eligible papers were those which investigated discrete cardiovascular clinical outcomes in TSH suppressed patients and meta-analysis of selected studies was performed using Revman 5.4.1. We fo...
Source: Hormone and Metabolic Research - June 9, 2023 Category: Endocrinology Authors: Yu, Jerry Kaur, Rajneesh Ayeni, Femi Emmanuel Eslick, Guy D. Edirimanne, Senarath Tags: Original Article: Endocrine Care Source Type: research

Hsa_Circ_0104206 is An Oncogenic circRNA in Colon Cancer by Targeting Mir-188 –3p/CCNA2 Axis
In conclusion, Circ_0104206 plays oncogenic roles in CC via the implication of miR-188–3p/CCNA2 network, which further discloses CC pathogenesis and supplies potential markers for CC. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 5, 2023 Category: Endocrinology Authors: Li, Zhong Li, Quanfu Chen, Zhuo Tags: Original Article: Endocrine Research Source Type: research

Identification of Basement Membrane Genes and Related Molecular Subtypes in Nonalcoholic Fatty Liver Disease
In conclusion, the present study identified novel potential BM-associated biomarkers and further explored the heterogeneity of NASH that might provide new insights into the diagnosis, assessment, management, and personalized treatment of NAFLD. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 2, 2023 Category: Endocrinology Authors: Wang, Zhaoxiang Qin, Huijuan Yang, Qichao Jia, Jue Yang, Ling Zhong, Shao Yuan, Guoyue Tags: Original Article: Endocrine Care Source Type: research

Alteration of Lipid Profile Between Subclinical Hypothyroidism and Well-Matched Controls: A Meta-Analysis
This study aimed to explore the changes in total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-c), and high-density lipoprotein cholesterol (HDL-c) between subclinical hypothyroidism (SCH) and well-matched euthyroid (EU) groups. Multiple databases were searched for publications before December 1, 2021, including cross-sectional studies on the association between SCH and lipid profile matched by age, gender, and BMI. Twenty-five articles with 3347 participants were included for meta-analysis. The results showed that the TC...
Source: Hormone and Metabolic Research - June 2, 2023 Category: Endocrinology Authors: Liu, Jinjin Chen, Yun Ren, Bingxuan He, Yanhong Li, Fan Wang, Lingbo Wan, Siyuan Liu, Lixiang Shen, Hongmei Tags: Original Article: Endocrine Care Source Type: research

Serum Uric Acid Levels and Recurrence Rate of Ischemic Stroke: A Meta-Analysis
Horm Metab Res DOI: 10.1055/a-2091-1951The role of serum uric acid as a factor in the recurrence of ischemic stroke stays unclear. Several studies have examined the relationship between serum uric acid and recurrence of acute ischemic stroke, with various results. Therefore, we carried out a meta-analysis to have a look at the relationship between serum uric acid levels and the potential danger of stroke recurrence in patients with ischemic stroke. Relevant experiments have been recognized via looking out the electronic databases and conference sessions. This pres...
Source: Hormone and Metabolic Research - June 2, 2023 Category: Endocrinology Authors: Li, Min Wang, Hongmei Gao, Yanjun Tags: Original Article: Endocrine Care Source Type: research

Factors Affecting Ablation Success After I-131 Radioactive Iodine Therapy in Low and Intermediate Risk Papillary Thyroid Cancer
Horm Metab Res DOI: 10.1055/a-2077-7246The study was to evaluate the effect of radioactive iodine (RAI) treatment application time and clinical, histopathological factors on ablation success in patients with operated papillary thyroid cancer (PTC) in low and intermediate-risk. One hundred sixty-one patients with PTC in the low and intermediate-risk were evaluated. Most patients (89.4%) were in the low-risk, and 10.6% were in the intermediate-risk. When the patients were divided into two groups according to the date of receiving RAI treatment after surger...
Source: Hormone and Metabolic Research - June 2, 2023 Category: Endocrinology Authors: Goksel, Sibel Avci, Ugur Tags: Original Article: Endocrine Care Source Type: research

Ferroptosis Signaling Pathways: Alzheimer's Disease
Horm Metab Res DOI: 10.1055/a-2084-3561The involvements of iron metabolism, lipid peroxidation, and oxidative stress in Alzheimer's disease (AD) development have recently received a lot of attention. We also observe that these pathogenic occurrences play a key role in regulating ferroptosis, a unique regulatory cell death that is iron-dependent, oxidative, and non-apoptotic. Iron is a crucial component that makes up a subunit of the oxidase responsible for lipid peroxidation. A family of non-heme iron enzymes known as lipoxygenases (LOXs) can cause ferroptosis by ...
Source: Hormone and Metabolic Research - May 31, 2023 Category: Endocrinology Authors: Maheshwari, Shubhrat Tags: Review Source Type: research

The Value of Visfatin in the Prediction of Metabolic Syndrome: A Systematic Review and Meta-Analysis
Horm Metab Res DOI: 10.1055/a-2051-6776Various studies have shown that visfatin may be connected to metabolic syndrome (MS). However, epidemiological studies yielded conflicting outcomes. The purpose of this article was to highlight the relationship between the plasma visfatin level and MS risk by conducting a meta-analysis of available literature. A comprehensive literature search of eligible studies was done up to January 2023. Data were presented as standard mean difference (SMD). Observational methodological meta-analysis was conducted to assess the relationsh...
Source: Hormone and Metabolic Research - May 25, 2023 Category: Endocrinology Authors: Jiang, Yingling Zhou, Lihua Tags: Original Article: Endocrine Care Source Type: research

Correction: CCND1-Induced Autophagy Contributes to Lymph Node Metastasis in Endometrial Cancer
Horm Metab Res DOI: 10.1055/a-2090-5663 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 19, 2023 Category: Endocrinology Authors: Su, Yi Zhou, Haonan Ma, Zhao Liu, Jing Li, Chen Tags: Erratum Source Type: research

Development of an Immune Prognostic Model for Clear Cell Renal Cell Carcinoma Based on Tumor Microenvironment
Horm Metab Res DOI: 10.1055/a-2079-2826Immune infiltration remains at a high level in clear cell renal cell carcinoma (ccRCC). It has been confirmed that immune cell infiltration in tumor microenvironment (TME) is intimately bound up with the progression and the clinical outcome of ccRCC. The prognostic model, developed based on different immune subtypes of ccRCC, has a predictive value in patients’ prognosis. RNA sequencing data, somatic mutation data of ccRCC and clinical information were acquired from the cancer genome atlas (TCGA) database. The key ...
Source: Hormone and Metabolic Research - May 16, 2023 Category: Endocrinology Authors: Wang, Munan Song, Qianqian Song, Zhijie Xie, Yuduan Tags: Original Article: Endocrine Care Source Type: research