Identification and Verification of a Glycolysis-Related lncRNA Prognostic Signature for Hepatocellular Carcinoma
In conclusion, this study preliminarily identified glycolytic-related prognostic features of lncRNAs in HCC and constructed a risk assessment model. The results of this study are expected to guide the prognosis assessment of clinical HCC patients. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 21, 2024 Category: Endocrinology Authors: Qiu, Fakai Yu, Guozheng Li, Mei Li, Zhubin Zhang, Qinyang Mu, Xudong Cheng, Yuan Zhai, Pengtao Liu, Qunyi Tags: Original Article: Endocrine Research Source Type: research

Low Concentration of Lipoprotein(a) is an Independent Predictor of Incident Type 2 Diabetes
Horm Metab Res DOI: 10.1055/a-2316-9124The aim of the study was to assess the association between lipoprotein(a) [Lp(a)] concentration and incident type 2 diabetes. A meta-analysis of qualified studies on the relationship of low levels of Lp(a) concentration with incident type 2 diabetes was conducted. PubMed and Cochrane libraries were searched for randomized controlled trials containing data on events. Seven randomized trials with 227178 subjects were included in this analysis. We found an inverse association of the levels of Lp(a) concentration with risk of typ...
Source: Hormone and Metabolic Research - May 21, 2024 Category: Endocrinology Authors: Liu, Wenhao Zhang, Guanzhao Nie, Zifan Guan, Xiangfeng Sun, Tingting Jin, Xiaodong Li, Bo Tags: Original Article: Endocrine Care Source Type: research

Is Stimulated Thyroglobulin Before Radioiodine Therapy a Useful Tool in Predicting Response to Initial Therapy in Patients with Differentiated Thyroid Carcinoma?
Horm Metab Res DOI: 10.1055/a-2318-5320Thyroglobulin (Tg) is an important tool to evaluate the persistence and recurrence risk in differentiated thyroid cancer (DTC). We aimed to evaluate the correlation between pre-radioiodine therapy stimulated Tg (pre-RAI Tg) levels and the first response to treatment evaluation, and to establish a cut-off pre-RAI Tg threshold for predicting an initial excellent response. Retrospective cohort study of DTC patients who underwent total thyroidectomy and radioiodine therapy. Response to therapy was evaluated 6 to 24 months after i...
Source: Hormone and Metabolic Research - May 21, 2024 Category: Endocrinology Authors: Jaeger, Fabiana Eidt, Laura Berton Guidolin, Kamille Landenberger, Giullia Menuci Chianca B ündchen, Cristiane Golbert, Lenara Mattevi, Vanessa Su ñé Meyer, Erika Laurini de Souza Tags: Original Article: Endocrine Care Source Type: research

Pretransplant Parathyroidectomy in Patients with Severe Secondary Hyperparathyroidism and Long-Term Effectiveness After Kidney Transplantation
Horm Metab Res DOI: 10.1055/a-2309-2240Kidney transplantation (KT) is the best option for patients with end-stage renal disease, but recipients still have legacy bone mineral disease from the pretransplant period, especially patients with severe secondary hyperparathyroidism (sHPT). Patients who had severe sHPT and underwent KT were analyzed retrospectively. Two groups were identified (patients with severe sHPT who had parathyroidectomy or calcimimetic before KT). Bone mineral density (BMD) was measured in the first year and last follow-up at the femoral neck, tot...
Source: Hormone and Metabolic Research - May 13, 2024 Category: Endocrinology Authors: Akcay, Omer Faruk Yeter, Haci Hasan Yuksel, Osman Guz, Galip Tags: Original Article: Endocrine Care Source Type: research

Serum Uric Acid Combined with Homocysteine as a Predictive Biomarker of Lupus Nephritis
In conclusion, serum UA and Hcy could be predictive biomarkers of LN, and joint detection of serum UA and Hcy might be useful in the clinical setting. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 6, 2024 Category: Endocrinology Authors: Zhang, Juan Tian, Jingjing Wang, Xiaoyuan Shen, Haili Tags: Original Article: Endocrine Care Source Type: research

Association Between Remnant Cholesterol and Risk of Hyperuricemia: A Cross-Sectional Study
Horm Metab Res DOI: 10.1055/a-2299-2914Remnant cholesterol (RC) is closely related to metabolic diseases. Our study aims to explore the relationship between RC and hyperuricemia. This cross-sectional study included 14 568 adults aged 20 years or older from the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2018 in the United States. RC is calculated by subtracting high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) from total cholesterol (TC). Hyperuricemia is defined by serum uric acid...
Source: Hormone and Metabolic Research - May 2, 2024 Category: Endocrinology Authors: Wang, Zhaoxiang Wu, Menghuan Yan, Han Zhong, Shao Xu, Ruijun Zhao, Zhiyong Yang, Qichao Tags: Original Article: Endocrine Care Source Type: research

Association Between HLA-DRB1 Alleles and Graves ʼ Disease in Asian Populations: A Meta-Analysis
Horm Metab Res DOI: 10.1055/a-2298-4366Graves’ disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is the most common cause of hyperthyroidism. Genetic studies have shown that human leukocyte antigen (HLA) plays an important role in the development of GD. In this article, we performed a meta-analysis determined to evaluate the relationship between HLA-DRB1 alleles and GD. This meta-analysis included 9 studies (3582 cases in the case group and 23070 cases in the control group) and 27 alleles was performed. The combined results showe...
Source: Hormone and Metabolic Research - May 2, 2024 Category: Endocrinology Authors: Li, Wenyi Ke, Tingyu Wang, Jia Zhu, Fangling Chi, Yan Tags: Original Article: Endocrine Care Source Type: research

Reply to the Letter to the Editor on “Prolactin is a Key Factor for Nonalcoholic Fatty Liver Disease in Obese Children”
Horm Metab Res DOI: 10.1055/a-2301-3272Dear Editor,The authors thank the writers 1 of the letter for reviewing and assessing our article 2, “Prolactin is a Key Factor for Nonalcoholic Fatty Liver Disease in Obese Children”. Overall, we agree that possible selection bias must be considered. However, in clinical studies, we found that hyperprolactinemia is mainly caused by pathological and idiopathic hyperprolactinemia. The former includes hypothalamic pituitary lesions (pituitary prolactinoma and empty sella syndrome, etc.), systemic diseases (hypothyroidism, e...
Source: Hormone and Metabolic Research - May 2, 2024 Category: Endocrinology Authors: Zhang, Jianwei Tags: Letter to the Editor Source Type: research

Re: Prolactin is a Key Factor for Nonalcoholic Fatty Liver Disease in Obese Children
Horm Metab Res DOI: 10.1055/a-2301-3225 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 2, 2024 Category: Endocrinology Authors: Triebel, Jakob Bertsch, Thomas Tags: Letter to the Editor Source Type: research

Association Between Triglyceride-Glucose Index and Diabetic Retinopathy: A Meta-Analysis
In conclusion, a high TyG index was associated with the risk of DR in T2D patients. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - April 26, 2024 Category: Endocrinology Authors: Yu, Lanchu Li, Bingqing Tags: Original Article: Endocrine Care Source Type: research

Clinical Efficacy of Bisphosphonates in Treating Osteoporosis in Diabetes Patients: A Meta-Analysis
Horm Metab Res DOI: 10.1055/a-2295-9335The aim of the study was to explore the clinical efficacy of bisphosphonates in patients with osteoporosis in diabetes patients by meta-analysis. Six databases were systematically searched from inception to January 30,2023. Studies evaluating the treatment of diabetic osteoporosis with bisphosphonates were included. Key outcome measures, such as bone mineral density (BMD), bone metabolism markers, pain improvement, and safety assessments, were extracted and analyzed. STATA MP V17.0 was used to calculate the combined effect si...
Source: Hormone and Metabolic Research - April 26, 2024 Category: Endocrinology Authors: Yang, Yuan-Xun Jin, Yan Tags: Original Article: Endocrine Care Source Type: research

Preoperative Serum Thyroglobulin Levels Predict Radioiodine Therapy Outcome in Papillary Thyroid Microcarcinoma Patients
Horm Metab Res DOI: 10.1055/a-2291-0340Our previous study showed that elevated preoperative thyroglobulin (pre-Tg) level predicted the risk of developing radioiodine refractory in PTC patients. In the present study, we aimed to evaluate the prognostic value of pre-Tg in papillary thyroid microcarcinoma (PTMC). After a specific inclusion and exclusion criteria were applied, a total of 788 PTMCs were enrolled from Jiangyuan Hospital affiliated to Jiangsu Institute of Nuclear Medicine between Jan 2015 and Dec 2019. Among them, 107 PTMCs were treated with radioiodine ...
Source: Hormone and Metabolic Research - April 15, 2024 Category: Endocrinology Authors: Cheng, Xian Fan, Yijun Ye, Wanzhong Xu, Shichen Wu, Jing Gao, Wenjing Bao, Jiandong Yu, Huixin Zhang, Li Tags: Original Article: Endocrine Care Source Type: research

Thyroglobulin Antibodies and Tumor Epitope-Specific Cellular Immunity in Papillary Thyroid Cancer
Horm Metab Res DOI: 10.1055/a-2278-6549Papillary thyroid carcinoma (PTC) is characterized by T cell infiltration and frequently by the presence of anti-thyroglobulin antibodies (TgAbs). The role of cellular immunity and of TbAbs in this context is a matter of debate. The aim of our study was to correlate the presence of TgAbs, tumor epitope-specific T cells and the clinical outcome of PTC patients. We studied n=183 consecutive patients with a diagnosis of PTC which were treated with total thyroidectomy plus 131I ablation. During a follow-up of in mean 97 months,...
Source: Hormone and Metabolic Research - April 15, 2024 Category: Endocrinology Authors: Allelein, Stephanie Ehlers, Margret Thoma, Taina Mattes-Gy örgy, Katalin Antke, Christina Mamlins, Eduards Muchalla, Mareike Giesel, Frederik Schott, Matthias Tags: Original Article: Endocrine Care Source Type: research

International Roadshow: New Advances in Endocrinology and Metabolic Diseases
Horm Metab Res 2024; 56: 259-260 DOI: 10.1055/a-2256-7180Dear Readers,Currently, there is a myriad of new developments in the field of endocrinology. In particular, significant strides have been made in the development of poly-agonists for the treatment of type 2 diabetes and obesity 1 2. Poly-agonists represent a novel therapeutic approach by combining multiple actions within a single molecule, targeting multiple receptors simultaneously to achieve enhanced efficacy. These innovative compounds aim to address the complex interplay of hormonal pathways involve...
Source: Hormone and Metabolic Research - April 11, 2024 Category: Endocrinology Authors: Steenblock, Charlotte Saber-Ayad, Maha M. Bornstein, Stefan R. Tags: Editorial Source Type: research

Association Between Triglyceride Glucose Index with Cognitive Impairment and Dementia in Adult Population: A Meta-Analysis
In conclusion, a high TyG index may be associated with higher risk of cognitive impartment and dementia in adult population. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - April 9, 2024 Category: Endocrinology Authors: Han, Yuqing Meng, Xu Wang, Dahui Tags: Original Article: Endocrine Care Source Type: research