Based on Clinical Research Matrix Metalloprotease (MMP) Inhibitors to
Promote Diabetic Wound Healing
Horm Metab Res DOI: 10.1055/a-2171-5879Chronic inflammation is a common factor in obesity, diabetes mellitus, and the
complications of diabetes, including diabetic wounds. These ulcers are
characterized by persistent lesions that are challenging to heal, significantly
decreasing patients’ quality of life and imposing a substantial
financial burden on society. MMP are zinc endopeptidases that play a role in
wound healing in response to various stimuli, including diabetes mellitus. MMP
levels fluctuate throughout the wound healing process in diabetic
pat...
Source: Hormone and Metabolic Research - October 5, 2023 Category: Endocrinology Authors: Yadav, Jagat Pal Tags: Review Source Type: research
Serological Screening for Celiac Disease and Gastrointestinal
Absorption Disorders in Patients with Autoimmune Endocrine
Diseases
This study aimed to evaluate the frequency of clinically overt or
silent CD in patients diagnosed with autoimmune endocrinopathy and the clinical
effects of silent CD in these endocrinopathies. The study included 166 patients
with known or newly diagnosed mono-/polyglandular AED and 90 age- and
gender-matched healthy controls. The patients were classified into four groups:
type 1 diabetes mellitus (DM) (n=44), Hashimoto’s thyroiditis
(HT) (n=68), Addison’s disease (AD) (n=17), and
autoimmune polyglandular syndrome (APS) (n=37). All subjects were
...
Source: Hormone and Metabolic Research - October 5, 2023 Category: Endocrinology Authors: Akkurt Kocaeli, Aysen Cander, Soner G ül, Özen Öz Sisman, P ınar Ersoy, Canan Erturk, Erd ınc Tags: Original Article: Endocrine Care Source Type: research
Correction: Factors of Central Lymph Node Metastasis in Papillary Thyroid Cancer
Based on C-TIRADS Analysis
Horm Metab Res 2023; 55: e5-e5 DOI: 10.1055/a-2177-1891 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | open access Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - October 5, 2023 Category: Endocrinology Authors: Huang, Weijun Chen, Deli Zhong, Minying Ye, Jieyi Zhi, Zhiyuan Xiao, Yanyan Zhong, Yuan Tags: Erratum Source Type: research
Marine Sponge-Derived Secondary Metabolites Modulate SARS-CoV-2 Entry
Mechanisms
Horm Metab Res DOI: 10.1055/a-2173-0277The emergence of SARS-CoV 2 caused the COVID-19 pandemic, resulting in numerous
global infections and deaths. In particular, people with metabolic diseases
display an increased risk of severe COVID 19 and a fatal outcome. Treatment
options for severe cases are limited, and the appearance of new virus variants
complicates the development of novel therapies. To better manage viral
infections like COVID 19, new therapeutic approaches are needed. Marine sponges
offer a natural and renewable source of unique bioactive agents. Thes...
Source: Hormone and Metabolic Research - October 4, 2023 Category: Endocrinology Authors: Steenblock, Charlotte Richter, Stefanie Lindemann, Dirk Ehrlich, Hermann Bornstein, Stefan R. Bechmann, Nicole Tags: Original Article: Endocrine Research Source Type: research
Association Between Circulating Resistin Level and Preeclampsia: A
Meta-Analysis
Horm Metab Res DOI: 10.1055/a-2167-0179Resistin, a diminutive secretory adipokine, has been linked to obesity and its
related ailments. A growing body of evidence suggests that resistin may also be
related to the pathogenesis preeclampsia. However, results of previous studies
were not consistent. We performed a systematic review and meta-analysis to
evaluate the level of circulating resistin in women with PE. A systematic search
of Medline, Web of Science, and Embase databases from inception to April 28,
2023, was conducted to identify studies that compared blood ...
Source: Hormone and Metabolic Research - October 4, 2023 Category: Endocrinology Authors: Xu, Xiangyu Du, Yi Wang, Ni Tags: Original Article: Endocrine Care Source Type: research
Correction: Insulin Inhibits Autophagy by Inhibiting the Binding of FoXO1 to the
Promoter Region of GABARAPL1
Horm Metab Res 2023; 55: e3-e3 DOI: 10.1055/a-2175-8370 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | open access Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - September 26, 2023 Category: Endocrinology Authors: Hong, Tao Wen, Jie Mei, Lang Li, Ruixiang Zhou, Junlin Li, Jiaoyang Xiao, Xin-Hua Tags: Erratum Source Type: research
High-Dose Rate Brachytherapy Combined with PD-1 Blockade as a
Treatment for Metastatic Adrenocortical Carcinoma – A Single Center Case
Series
Horm Metab Res DOI: 10.1055/a-2150-3944The response rate of advanced adrenocortical carcinoma (ACC) to standard
chemotherapy with mitotane and etoposide/doxorubicin/cisplatin
(EDP-M) is unsatisfactory, and benefit is frequently short lived. Immune
checkpoint inhibitors (CPI) have been examined in patient’s refractory
to EDP-M, but objective response rates are only approximately 15%.
High-dose rate brachytherapy (HDR-BT) is a catheter-based internal radiotherapy
and expected to favorably combine with immunotherapies. Here we describe three
cases of pati...
Source: Hormone and Metabolic Research - September 25, 2023 Category: Endocrinology Authors: Schwarzlmueller, Paul Corradini, Stefanie Seidensticker, Max Zimmermann, Petra Schreiner, Jochen Maier, Tanja Triebig, Alexandra Kn ösel, Thomas Pazos, Montserrat Pfluger, Thomas Weigand, Isabel Belka, Claus Ricke, Jens Reincke, Martin Schmidmaier, Ralf Tags: Original Article: Endocrine Care Source Type: research
Insulin Inhibits Autophagy by Inhibiting the Binding of FoXO1 to the
Promoter Region of GABARAPL1
Horm Metab Res 2023; 55: 634-641 DOI: 10.1055/a-2119-3301Hyperinsulinemia and insulin resistance in T2D have a potent suppressive effect
on hepatic autophagy, however, the underlying mechanisms remain unclear. To
explore the effect of insulin on hepatic autophagy and its possible signaling
pathways, HL-7702 cells were treated with insulin with or without insulin
signaling inhibitors. The interaction between insulin and the promoter region of
GABARAPL1 was assessed through luciferase assay and EMSA. There were significant
dose-dependent decreases in the number of i...
Source: Hormone and Metabolic Research - September 7, 2023 Category: Endocrinology Authors: Hong, Tao Wen, Jie Mei, Lang Li, Ruixiang Zhou, Junlin Li, Jiaoyang Xiao, Xin-Hua Tags: Original Article: Endocrine Research Source Type: research
Association Between the XRCC1, GSTM1, and GSTT1 Polymorphisms in
Model of Thyroid Cancer: A Meta-Analysis
In conclusion, this study found that the
proportion of XRCC1 polymorphisms (rs25489, AA) in thyroid cancer was lower than
that of the normal control group. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - September 7, 2023 Category: Endocrinology Authors: Yang, Wenhan Liu, Wanyu Zhu, Lei Lin, Yaqi Meng, Zilu Wang, Yudong Tags: Original Article: Endocrine Care Source Type: research
Positive Effects of Physical Activity on Prescription on Glycemic
Control, Fitness, and Quality of Life in Newly Diagnosed Type 2 Diabetic
Patients
In conclusion, the fact that even a
small change in mean step counts over three months had a beneficial effect on
health-related outcomes in drug-naïve T2D patients can have large
implications for treatment and management practices, not least in a
middle-income country like Vietnam. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - September 7, 2023 Category: Endocrinology Authors: Nguyen, Tam Ngoc Vu, Huyen Thi Thanh Khuong, Long Quynh van der Ploeg, Ingeborg Sundberg, Carl Johan Tags: Original Article: Endocrine Care Source Type: research
Long-Term Efficacy and Safety of Recombinant Human Growth Hormone in
Children Born Small for Gestational Age
This study was
conducted to assess the long-term efficacy and safety of GH treatment in
children born SGA. One hundred and twenty prepubertal SGA children who did not
achieve catch-up growth with height remained less than –2 standard
deviations (SD) below gender-specific height were enrolled in this two-year,
randomized, dose-comparative study followed by an extension study of up to 10
years. Daily subcutaneous injections of 0.23 mg/kg/week
[low-dose (LD) group] or 0.46 mg/kg/week [high-dose (HD)
group] somatropin were given for 104 weeks...
Source: Hormone and Metabolic Research - September 7, 2023 Category: Endocrinology Authors: Wu, Wei Gong, Chunxiu Li, Yuchuan Hu, Yuhua Gong, Haihong Fu, Junfen Huang, Ke Li, Pin Luo, Xiaoping Tags: Original Article: Endocrine Care Source Type: research
Factors of Central Lymph Node Metastasis in Papillary Thyroid Cancer
Based on C-TIRADS Analysis
Horm Metab Res 2023; 55: 585-591 DOI: 10.1055/a-2142-4811To study risk factors for central lymph node metastasis (CLNM) in papillary
thyroid cancer (PTC) using the Chinese Thyroid Imaging Reporting and Data System
(C-TIRADS). We retrospectively analysed patients who underwent PTC surgery and
central lymph node dissection at First People’s Hospital of Foshan City.
The clinical and ultrasonic data of the patients from 1150 cases were analysed
by multivariate regression to evaluate the correlation between grayscale
ultrasound (US) features, C-TIRADS score, and the ...
Source: Hormone and Metabolic Research - September 7, 2023 Category: Endocrinology Authors: Huang, Weijun Chen, Deli Zhong, Minying Ye, Jieyi Zhi, Zhiyuan Xiao, Yanyan Zhong, Yuan Tags: Original Article: Endocrine Care Source Type: research
The Interplay Between COVID-19 and Pediatric Endocrine Disorders.
What have we Learned After More than Three Years of the
Pandemic?
Horm Metab Res DOI: 10.1055/a-2152-4590As an increased body of COVID-19 related research is now available, it becomes
apparent that the effects of COVID-19 extend beyond that of the respiratory
system. Among others, the endocrine system is particularly vulnerable to
perturbation from the COVID-19 infection. The present scoping review summarizes
the bidirectional relationship between COVID-19 and endocrine system in children
and adolescents, by describing both the possible susceptibility of children and
adolescents without endocrinopathies to endocrine disorders fo...
Source: Hormone and Metabolic Research - September 6, 2023 Category: Endocrinology Authors: Kostopoulou, Eirini Tags: Review Source Type: research
Correction: Adrenal Crisis – Definition, Prevention and Treatment:
Results from a Delphi Survey
Horm Metab Res DOI: 10.1055/a-2157-2308 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - August 25, 2023 Category: Endocrinology Authors: Kienitz, Tina Bechmann, Nicole Deutschbein, Timo Hahner, Stefanie Honegger, J ürgen Kroiss, Matthias Quinkler, Marcus Rayes, Nada Reisch, Nicole Willenberg, Holger Sven Meyer, Gesine Tags: Erratum Source Type: research
Adrenal Crisis – Definition, Prevention and Treatment:
Results from a Delphi Survey
This study
provides pragmatic strategies to identify and treat patients prone to adrenal
crisis, thereby highlighting the need for an improved management of patients
with adrenal insufficiency. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - August 10, 2023 Category: Endocrinology Authors: Kienitz, Tina Bechmann, Nicole Deutschbein, Timo Hahner, Stefanie Honegger, J ürgen Kroiss, Matthias Quinkler, Marcus Rayes, Nada Reisch, Nicole Willenberg, Holger Sven Meyer, Gesine Tags: Original Article: Endocrine Care Source Type: research
