Correction: Recent Advances of LncRNA H19 in Diabetes
Horm Metab Res 2022; 54: e2-e2 DOI: 10.1055/a-1828-6861 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 4, 2022 Category: Endocrinology Authors: Bi, Ye Wang, Yao Sun, Xianglan Tags: Erratum Source Type: research
Recent Advances of LncRNA H19 in Diabetes
Horm Metab Res 2022; 54: 212-219 DOI: 10.1055/a-1769-5032Diabetes mellitus (DM) causes damage to major organs, including the heart, liver,
brain, kidneys, eyes, and blood vessels, threatening the health of the
individuals. Emerging evidence has demonstrated that lncRNAs has important
functions in the pathogenesis of human diseases, such as cancers,
neurodegenerative diseases, cardiac fibroblast phenotypes, hypertension, heart
failure, atherosclerosis and diabetes. Recently, H19, a lncRNA, has been
reported to shown to participate in the regulatory process of muscl...
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Bi, Ye Wang, Yao Sun, Xianglan Tags: Review Source Type: research
Angiotensin(1 –7) Improves Islet Function in Diabetes Through
Reducing JNK/Caspase-3 Signaling
Horm Metab Res 2022; 54: 250-258 DOI: 10.1055/a-1796-9286The aim of this study is to investigate whether Angiotensin (1–7), the
physiological antagonist of Angiotensin II (AngII), has antidiabetic activity
and the possible mechanism. Male Wistar rats were randomly divided into 3
groups: control group fed the normal diet, DM group fed high-fat diet and
injected with STZ, and Angiotensin (1–7) group receiving injection of
STZ followed by Angiotensin (1–7) treatment. Serum Ang II, fasting blood
glucose, insulin, HOMA-IR, and HOMA-beta were determined in control...
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Liu, Jing Li, Xing Wang, Xiaoyan Peng, Lina Song, Guoning He, Junhua Tags: Original Article: Endocrine Research Source Type: research
Precision Medicine Approach for Cardiometabolic Risk Factors in
Therapeutic Apheresis
This study revealed that proteomic analysis
correlates well with routine clinical chemistry in these patients. The method is
eminently suited to discover new biomarkers and risk factors for cardiovascular
disease in these patients. Different filters achieve reduction and removal of
proatherogenic proteins in different quantities. This includes not only
apolipoproteins, C-reactive protein, fibrinogen, and plasminogen but also
proteins like complement factor B (CFAB), protein AMBP, afamin, and the low
affinity immunoglobulin gamma Fc region receptor III-A ...
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Yin, X. Takov, K. Straube, R. Voit-Bak, K. Graessler, J. Julius, U. Tselmin, S. Rodionov, R. Barbir, M. Walls, M. Theofilatos, K. Mayr, M. Bornstein, S.R. Tags: Original Article: Endocrine Care Source Type: research
The Importance of DHEA-S Levels in Cushing ’s Syndrome; Is
There a Cut-off Value in the Differential Diagnosis?
This study showed that the cut-off value of DHEA-S level less than
20% of the reference interval could be used for differential diagnosis
of CD and adrenal CS with high sensitivity and specificity, and it should be
taken into the initial evaluation. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Ciftci, Sema Soyluk, Ozlem Selek, Alev Erol, Selvinaz Hekimsoy, Zeliha Esen, Ayse Dursun, Huseyin Sahin, Serdar Oruk, Gonca Mert, Meral Soylu, Huseyin Yurekli, Banu Sarer Ertorer, Melek Eda Omma, Tulay Evran, Mehtap Adas, Mine Tanrikulu, Seher Aydin, Kadr Tags: Original Article: Endocrine Care Source Type: research
Early Renin Recovery After Adrenalectomy in Aldosterone-Producing
Adenomas: A Prospective Study
In conclusion, our prospective study
shows the borderline persistent post-operative hypoaldosteronism in the presence
of early renin recovery indicating incapability of the zona glomerulosa of the
remaining adrenal gland to produce aldosterone. These findings contribute to the
comprehension of differences in renin and aldosterone regulation in APA
patients, although both are part of the same interconnected system. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text ...
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Mermejo, Livia M. Elias, Paula C.L. Molina, Carlos A.F. Tucci, Silvio Muglia, Valdair F. Elias, Jorge Antonini, Sonir R. de Castro, Margaret Moreira, Ayrton C. Tags: Original Article: Endocrine Care Source Type: research
Diagnostic Utility of Procalcitonin for Sporadic Medullary Thyroid
Carcinoma in Patients with Nodular Disease and Mild or Moderate
Hypercalcitoninemia
Horm Metab Res 2022; 54: 220-223 DOI: 10.1055/a-1773-1127Many authors recommend the measurement of serum calcitonin (Ctn) to screen for
sporadic medullary thyroid carcinoma (MTC) in patients with thyroid nodules. In
this situation, procalcitonin (pro-Ctn) would have greater utility in patients
with hypercalcitoninemia<100 pg/ml. The aim of this
study was to evaluate the utility of pro-Ctn in patients with thyroid nodules
and without a suspicion of familial MTC or type 2 multiple endocrine neoplasia
who had mild or moderate hypercalcitoninemia without an appar...
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Rosario, Pedro Weslley Mour ão, Gabriela Franco Tags: Original Article: Endocrine Care Source Type: research
Recent Advances of LncRNA H19 in Diabetes LncRNA H19 in
Diabetes
Horm Metab Res 2022; 54: 212-219 DOI: 10.1055/a-1769-5032Diabetes mellitus (DM) causes damage to major organs, including the heart, liver,
brain, kidneys, eyes, and blood vessels, threatening the health of the
individuals. Emerging evidence has demonstrated that lncRNAs has important
functions in the pathogenesis of human diseases, such as cancers,
neurodegenerative diseases, cardiac fibroblast phenotypes, hypertension, heart
failure, atherosclerosis and diabetes. Recently, H19, a lncRNA, has been
reported to shown to participate in the regulatory process of muscl...
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Bi, Ye Wang, Yao Sun, Xianglan Tags: Review Source Type: research
FGF21: A Novel Regulator of Glucose and Lipid Metabolism and
Whole-Body Energy Balance
Horm Metab Res 2022; 54: 203-211 DOI: 10.1055/a-1778-4159Fibroblast growth factor (FGF) 21 is a recently recognized metabolic regulator
that evokes interest due to its beneficial action of maintaining whole-body
energy balance and protecting the liver from excessive triglyceride production
and storage. Together with FGF19 and FGF23, FGF21 belongs to the FGF family with
hormone-like activity. Serum FGF21 is generated primarily in the liver under
nutritional stress stimuli like prolonged fasting or the lipotoxic diet, but
also during increased mitochondrial and endo...
Source: Hormone and Metabolic Research - April 12, 2022 Category: Endocrinology Authors: Szczepa ńska, Ewa Gietka-Czernel, Ma łgorzata Tags: Review Source Type: research
COVID-19 and Diabetic Nephropathy
Horm Metab Res DOI: 10.1055/a-1819-4822Diabetic nephropathy is the most common condition that requires a chronic renal
replacement therapy, such as hemodialysis, peritoneal dialysis, kidney
transplantation, or simultaneous kidney-pancreas transplantation. Chronic kidney
disease progression, that is the loss of nephrons, which causes the continuous
decline of the eGFR, underlies the pathogenesis of diabetic nephropathy. During
the COVID-19 pandemic, it became clear that diabetic nephropathy is amongst the
independent risk factors that predicts unfavourable outcome ...
Source: Hormone and Metabolic Research - April 6, 2022 Category: Endocrinology Authors: Maremonti, Francesca Locke, Sophie Tonnus, Wulf Beer, Kristina Brucker, Anne Gonzalez, Nadia Zamora Latk, Marcus Belavgeni, Alexia Hoppenz, Paul Hugo, Christian Linkermann, Andreas Tags: Review Source Type: research
Cardiac Remodeling in Hypertension: Clinical Impact on Brain, Heart,
and Kidney Function
Horm Metab Res DOI: 10.1055/a-1793-6134Hypertension is the most common causative factor of cardiac remodeling, which, in
turn, has been associated with changes in brain and kidney function. Currently,
the role of blood biomarkers as indices of cardiac remodeling remains unclear.
In contrast, cardiac imaging, including echocardiography and cardiovascular
magnetic resonance (CMR), has been a valuable noninvasive tool to assess cardiac
remodeling. Cardiac remodeling during the course of systemic hypertension is not
the sole effect of the latter. “Remodeling” of o...
Source: Hormone and Metabolic Research - March 29, 2022 Category: Endocrinology Authors: Mavrogeni, Sophie Piaditis, George Bacopoulou, Flora Chrousos, George P. Tags: Review Source Type: research
An LC-MS/MS Methodological Framework for Steroid Hormone
Measurement from Human Serum
Horm Metab Res DOI: 10.1055/a-1768-0709Estrogens and androgens are important regulators of sexual development and
physiological processes in men and women, acting on numerous organs throughout
the body. Moreover, they can contribute to a variety of pathologies, including
osteoporosis, cancer, and cardiovascular and neurologic diseases. Analysis of
estrogens and androgens in biological samples has been commonly performed using
immunoassays for many years. However, these assays are suboptimal, as there is
cross-reactivity with similar analytes, and they have moderat...
Source: Hormone and Metabolic Research - March 29, 2022 Category: Endocrinology Authors: Gasbarrino, Karina Daly, Edward Daskalopoulou, Stella S. Tags: Original Article: Endocrine Care Source Type: research
Cardiac Autonomic Neuropathy in Patients with Newly Diagnosed
Carbohydrate Disturbances
In conclusion, CAN has a higher prevalence on patients with newly diagnosed
diabetes compared to prediabetic and normoglycemic subjects, while the patients
with blood glucose>8.5 mmol/l on the 60th-minute of OGTT
have higher prevalence of CAN independently of their glycemic status. SUDOSCAN
testing can be used to assess the risk of CAN and to select patients that should
undergo further testing. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormon...
Source: Hormone and Metabolic Research - March 24, 2022 Category: Endocrinology Authors: Gateva, Antoaneta Kamenov, Zdravko Tags: Original Article: Endocrine Care Source Type: research
Subacute Thyroiditis Following SARS-CoV-2 Vaccines: Six Cases Report
and Review of the Literature
Horm Metab Res DOI: 10.1055/a-1804-9561Subacute thyroiditis (SAT) is an inflammatory disease of the thyroid that
develops following viral upper respiratory tract infections. SARS-CoV-2 virus,
the cause of COVID-19, binds to the Angiotensin-Converting Enzyme-2 (ACE2)
molecule expressed on the target cell surface. Thyroid gland shows high levels
of ACE2 expression. The cases of SARS-CoV-2-related subacute thyroiditis and
Graves’ disease have been reported. It has recently been noted that
vaccines for SARS-CoV-2 also induce autoimmune and inflammatory reactions. We...
Source: Hormone and Metabolic Research - March 22, 2022 Category: Endocrinology Authors: Kurtulmus, Neslihan Kayikci, Kubra Tags: Original Article: Endocrine Care Source Type: research
Anti-Mullerian Hormone Levels Increase After Bariatric Surgery in
Obese Female Patients With and Without Polycystic Ovary Syndrome
In conclusion, our study suggests that the significantly
increased AMH levels by losing weight with bariatric surgery in patients with
morbid obesity with and without PCOS may indicate the improvement of
fertilization potential. It could be considered when evaluating fertility in
patients with morbid obesity. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - March 11, 2022 Category: Endocrinology Authors: Buyukkaba, Mitat Turgut, Seda Ilhan, Mahmut Muzaffer Ekinci, Iskender Yayl ım, İlhan Zeybek, Sakir Umit Turan, Saime Tasan, Ertugrul Karaman, Ozcan Tags: Endocrine Care Source Type: research