Can Serum Thyroglobulin Levels Help to Identify the Involved Neck Compartment of Differentiated Thyroid Carcinoma?
Horm Metab Res DOI: 10.1055/a-1903-1800We aimed to evaluate the predictive ability of serum thyroglobulin (Tg) levels on the localization of the metastatic lymph node compartments in locoregional metastases of papillary thyroid cancer (PTC). This retrospective study included 143 patients who underwent neck dissections for a total of 172 for persistent/recurrent locoregional PTC. They were grouped according to the localization of lymph node metastasis (LNM): Central (C-LNM), Lateral (L-LNM), both central and lateral LNM (C+L LNM). To confirm that the Tg c...
Source: Hormone and Metabolic Research - September 2, 2022 Category: Endocrinology Authors: Bah çecioğlu, Adile Begüm Ozkan, Elgin Araz, Mine Elhan, Atilla Halil Erdo ğan, Murat Faik Tags: Original Article: Endocrine Care Source Type: research

Correction: COVID-19 and Therapeutic Apheresis
Horm Metab Res 2022; 54: e5-e5 DOI: 10.1055/a-1930-9384 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - September 2, 2022 Category: Endocrinology Authors: Tselmin, Sergey Julius, Ulrich Jarzebska, Natalia Rodionov, Roman N. Tags: Erratum Source Type: research

Novel Therapeutic Agents for Rare Diseases of Calcium and Phosphate Metabolism
Horm Metab Res DOI: 10.1055/a-1917-0519The last decade has been revolutionary regarding the management of rare bone diseases caused by impaired calcium and phosphate metabolism. Elucidation of the underlying genetic basis and pathophysiologic alterations has been the determinant factor for the development of new, disease-specific treatment agents. The phosphaturic hormone Fibroblast Growth Factor 23 (FGF23) possesses a critical role in the pathogenesis of various hypophosphatemic disorders. Among them, the genetic disorder of X-linked hypophosphatemia and the acqu...
Source: Hormone and Metabolic Research - September 1, 2022 Category: Endocrinology Authors: Roumpou, Afroditi Yavropoulou, Maria P Chronopoulos, Efstathios Kassi, Eva Tags: Review Source Type: research

Influence of Sodium-Glucose Cotransporter-2 Inhibitors on Plasma Adiponectin in Patients with Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials
In conclusion, SGLT-2 inhibitors could significantly increase plasma adiponectin as compared with placebo in T2DM patients. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - September 1, 2022 Category: Endocrinology Authors: Wang, Yang Xia, Ning Tags: Original Article: Endocrine Care Source Type: research

Serum Calcium, Magnesium, and Phosphorus Levels in Patients with COVID-19: Relationships with Poor Outcome and Mortality
In conclusion, CorrCa can be used as a simple and reliable marker of poor outcome in patients with COVID-19, although not to predict the risk of in-hospital mortality. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - August 23, 2022 Category: Endocrinology Authors: D íez, Juan J. Iglesias, Pedro Garc ía, Agustín Mart ín-Casasempere, Ignacio Bernab éu-Andréu, Francisco A. Tags: Original Article: Endocrine Care Source Type: research

MiR-30a-3p Targeting FLT1 Modulates Trophoblast Cell Proliferation in the Pathogenesis of Preeclampsia
In conclusion, persistent high levels of FLT1 and miR-30a-3p may pose adverse effects on angiogenesis and trophoblast proliferation in placenta of PE patients. Therefore, targeting FLT1 and miR-30a-3p may serve as ideal strategies for managing patients with PE. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - August 18, 2022 Category: Endocrinology Authors: Wang, Yuping Wang, Lanlan Yu, Xiaoyan Gong, Wenwen Tags: Original Article: Endocrine Research Source Type: research

LncRNA MAGI2-AS3 Inhibits Prostate Cancer Progression by Targeting the miR-142-3p
Horm Metab Res DOI: 10.1055/a-1891-6864Prostate cancer is a common male cancer with high morbidity and mortality worldwide. According to current research, the integration of long non-coding RNA (lncRNAs) and microRNA(miRNAs) can be expressed in a variety of cancers and play an important role in diagnosis. Based on this, this study explored the clinical role of lncRNA MAGI2-AS3 (MAGI2-AS3) in prostate cancer. By detecting the expression levels of MAGI2-AS3 and miR-142-3p, the correlation between the MAGI2-AS3 expression and the characteristics of clinical data was ...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Hu, Renbao Wu, Pei Liu, Jianhui Tags: Original Article: Endocrine Research Source Type: research

COVID-19 and Therapeutic Apheresis
We describe here the rationale and the initial attempts of TA treatment in severe cases of acute COVID-19. We next review the evidence for the role of autoimmunity, microcirculatory changes and inflammation in pathogenesis of Long/Post COVID and the rationale for targeting those pathogenic processes by different methods of TA. Finally, we discuss the impact of COVID-19 pandemic on patients, who undergo regular TA treatments due to their underlying chronic conditions, with the specific focus on the patients with inherited lipid diseases being treated at t...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Tselmin, Sergey Julius, Ulrich Jarzebska, Natalia Rodionov, RomanN. Tags: Review Source Type: research

Treating Insulin Resistance with Intermittent Personalized Nutrition to Sustain Metabolic Health and Functioning Immune System for Risk Reduction of Viral Diseases Especially COVID-19 and Long-COVID
Horm Metab Res 2022; 54: 567-570 DOI: 10.1055/a-1864-8234The Covid-19 pandemic has provided new and strong evidence for poor outcomes of viral infection in patients with poor metabolic health. Insulin resistance is at the root of many metabolic conditions and a key driver of their progression as it promotes ineffectual inflammation whilst impairing immune functions. In a vicious circle, insulin resistance facilitates SARS-CoV-2 infection, whilst infection drives insulin resistance. We discuss the underlying mechanisms and explore ways to improve metabolic health a...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Rohner, Markus Schwarz, Peter E. H. Bornstein, Stefan R. Tags: Review Source Type: research

Long-COVID, Metabolic and Endocrine Disease
Horm Metab Res 2022; 54: 562-566 DOI: 10.1055/a-1878-9307In the aftermath of the corona pandemic, long-COVID or post-acute COVID-19 syndrome still represents a great challenge, and this topic will continue to represent a significant health problem in the coming years. At present, the impact of long-COVID on our health system cannot be fully assessed but according to current studies, up to 40% of people who have been infected with SARS-CoV-2 suffer from clinically relevant symptoms of long-COVID syndrome several weeks to months after the acute phase. The main sympt...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Bornstein, Stefan R. Cozma, Diana Kamel, Margrit Hamad, Mawieh Mohammad, Mohammad G. Khan, Naveed A. Saber, Maha M. Semreen, Mohammad H. Steenblock, Charlotte Tags: Review Source Type: research

Adrenal Gland Function and Dysfunction During COVID-19
Horm Metab Res 2022; 54: 532-539 DOI: 10.1055/a-1873-2150The coronavirus disease 2019 (COVID-19) pandemic is currently one of the major health concerns worldwide accounting for many deaths and posing a great social and economic burden. Early activation of adrenal hormone secretion is pivotal to surviving systemic microbial infections. In addition, clinical studies demonstrated that glucocorticoids might also be beneficial in reducing disease progression and life deterioration in certain patients with COVID-19. Recent studies demonstrated that SARS-CoV-2 might targ...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Kanczkowski, Waldemar Gaba, Waqar Haider Krone, Nils Varga, Zsuzsanna Beuschlein, Felix Hantel, Constanze Andoniadou, Cynthia Bornstein, Stefan R. Tags: Review Source Type: research

Diabetes and COVID-19: Short- and Long-Term Consequences
Horm Metab Res 2022; 54: 503-509 DOI: 10.1055/a-1878-9566When the corona pandemic commenced more than two years ago, it was quickly recognized that people with metabolic diseases show an augmented risk of severe COVID-19 and an increased mortality compared to people without these comorbidities. Furthermore, an infection with SARS-CoV-2 has been shown to lead to an aggravation of metabolic diseases and in single cases to new-onset metabolic disorders. In addition to the increased risk for people with diabetes in the acute phase of COVID-19, this patient group also ...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Steenblock, Charlotte Hassanein, Mohamed Khan, Emran G. Yaman, Mohamad Kamel, Margrit Barbir, Mahmoud Lorke, Dietrich E. Rock, John A. Everett, Dean Bejtullah, Saqipi Heimerer, Adrian Tahirukaj, Ermal Beqiri, Petrit Bornstein, Stefan R. Tags: Review Source Type: research

Obesity and COVID-19: What are the Consequences?
Horm Metab Res 2022; 54: 496-502 DOI: 10.1055/a-1878-9757Obesity is an increasing health problem all over the world. In combination with the current COVID-19 pandemic, this has turned into a massive challenge as individuals with overweight and obesity at all ages show a significant increase in their risk of getting severe COVID-19. Around 20% of all patients that were hospitalized for COVID-19 suffered from obesity alone, whereas obesity in combination with other metabolic comorbidities, such as type 2 diabetes and hypertension, account for up to 60% of all hospit...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Steenblock, Charlotte Hassanein, Mohamed Khan, Emran G. Yaman, Mohamad Kamel, Margrit Barbir, Mahmoud Lorke, Dietrich E. Everett, Dean Bejtullah, Saqipi Lohmann, Tobias Lindner, Uwe Tahirukaj, Ermal Jirjees, Feras Jassim Soliman, Sameh S.M. Quitter, Fried Tags: Review Source Type: research

The Role of Endocrine and Metabolic System in COVID-19 Disease – The Transcampus Experience and Review of Evidence From International Collaborating Groups
Horm Metab Res 2022; 54: 494-495 DOI: 10.1055/a-1873-2300The COVID-19 Pandemic has led to a world health crisis with major socioeconomic consequences that have deeply affected our daily lives. Until the end of May 2022, more than 500 million people have been infected by COVID-19 and more than 6 million have died from the disease. Unprecedented efforts in research, illustrated by the more than 250 000 publications in PubMed, have led to the identification of important pathophysiological mechanisms affected by SARS-CoV-2 and have resulted in the development of effec...
Source: Hormone and Metabolic Research - August 9, 2022 Category: Endocrinology Authors: Perakakis, Nikolaos Barthel, Andreas Bornstein, Stefan R. Tags: Editorial Source Type: research

A Systematic Review and Meta-Analysis of Metabolic Syndrome Prevalence in Chinese Inpatients with Bipolar Disorder
Horm Metab Res DOI: 10.1055/a-1882-8423To study prevalence of metabolic syndrome in Chinese patients with bipolar disorder. We searched Chinese literature related to the study in prevalence of metabolic syndrome in bipolar disorder in Chinese language,among which results such as comments, letters, reviews and case reports were excluded. The prevalence of metabolic syndrome in bipolar disorder was synthesized and discussed. A total of 1562 subjects were included in 11 studies. The prevalence of MetS in bipolar disorder was 33% (95%CI=0.29-0.37), which was higher significantly than normal control (10.82%), but similar to sch...
Source: Hormone and Metabolic Research - July 20, 2022 Category: Endocrinology Authors: Tao, Hejian Shen, Dong Zhou, Yong Sun, Fengli Li, Guorong Jin, Weidong Tags: Original Article: Endocrine Care Source Type: research