The Impact of COVID-19 in Bone Metabolism: Basic and Clinical Aspects
Horm Metab Res DOI: 10.1055/a-1825-9641The use of standard procedures for the diagnosis of osteoporosis and assessment of fracture risk significantly decreased during the COVID-19 pandemic, while the incidence of fragility fractures was mostly unaltered. Both COVID-19 per se and its treatments are associated with a negative impact on bone health. Preclinical models show that mice infected with SARS-CoV2 even without symptoms display loss of trabecular bone mass two weeks post infection, due to increased numbers of osteoclasts. Osteoporosis medications do not aggravate the clinical course of COVID-19, while preclinical data...
Source: Hormone and Metabolic Research - June 15, 2022 Category: Endocrinology Authors: Tsourdi, E. Hofbauer, Lorenz Rauner, Martina Tags: Review Source Type: research
Liver, NAFLD and COVID-19
Horm Metab Res DOI: 10.1055/a-1834-9008Coronavirus disease 2019 (COVID-19) is characterized by a wide clinical spectrum
that includes abnormalities in liver function indicative of liver damage.
Conversely, people with liver diseases are at higher risk of severe COVID-19. In
the current review, we summarize first the epidemiologic evidence describing the
bidirectional relationship between COVID-19 and liver function/liver
diseases. Additionally, we present the most frequent histologic findings as well
as the most important direct and indirect mechanisms supporting ...
Source: Hormone and Metabolic Research - June 14, 2022 Category: Endocrinology Authors: Hoffmann, Carlotta Gerber, Philipp A. Cavelti-Weder, Claudia Licht, Louisa Kotb, Reham Al Dweik, Rania Cherfane, Michele Bornstein, Stefan Perakakis, Nikolaos Tags: Review Source Type: research
Investigation of the Relationship Between Autoimmune and Nodular
Goiter in Patients with Euthyroid Polycystic Ovary Syndrome and Their
Phenotypes
Horm Metab Res 2022; 54: 396-406 DOI: 10.1055/a-1825-0316Polycystic ovary syndrome (PCOS) is an endocrine disorder that frequently affects
women of reproductive age. In PCOS, the incidence of thyroid diseases has
increased in addition to reproductive and metabolic problems. To compare thyroid
nodule, volume, autoimmunity, and thyroid function tests of euthyroid PCOS and
its phenotypes. The files of 178 patients with PCOS aged 18–45 years and
92 patients with no disease who were matched for body mass index were
retrospectively scanned. Women with PCOS were divide...
Source: Hormone and Metabolic Research - June 13, 2022 Category: Endocrinology Authors: Altunta ş, Seher Çetinkaya G üneş, Mutlu Tags: Original Article: Endocrine Care Source Type: research
First Clinical Study on Long-Acting Growth Hormone Therapy in
Children with Turner Sydrome
Horm Metab Res 2022; 54: 389-395 DOI: 10.1055/a-1842-0724Study on long-acting growth hormone (LAGH) therapy in Turner syndrome (TS) is a
2-year retrospective study including patients diagnosed with TS from
2018–2021. Patients were divided into four groups: Group 1 to 4 were low
dose (0.1 mg/kg/ w), high-dose
(0.2 mg/kg/w) LAGH, daily GH
(0.38 mg/kg/w), and untreated control. The efficacy and
safety data were analyzed. Seventy-five TS cases with the age 7.9±2.9
years and the bone age 6.8±2.8 years were recruited. In year 1: The
change ...
Source: Hormone and Metabolic Research - June 13, 2022 Category: Endocrinology Authors: Gao, Xinying Chen, Jiajia Cao, Bingyan Dou, Xinyu Peng, Yaguang Su, Chang Qin, Miao Wei, Liya Fan, Lijun Zhang, Beibei Gong, Chunxiu Tags: Original Article: Endocrine Care Source Type: research
Differences in Clinical Aspects Between Subacute Thyroiditis
Associated with COVID-19 Vaccines and Classical Subacute
Thyroiditis
Horm Metab Res 2022; 54: 380-388 DOI: 10.1055/a-1840-4374Subacute thyroiditis (SAT) developed after SARS-CoV-2 vaccines has been less
studied. We aimed to compare classical SAT and SAT developed after SARS-CoV-2
vaccines in the context of clinical aspects. Adults with SAT detected in 90 days
of COVID-19 vaccination (CoronaVac or Pfizer/BioNTech) were grouped as
Vac-SAT. Those with a history of SARS-CoV-2 or upper respiratory tract infection
in 6 months before the vaccination, or vaccination with another antiviral
vaccine after COVID-19 vaccination were excluded. T...
Source: Hormone and Metabolic Research - June 13, 2022 Category: Endocrinology Authors: Topalo ğlu, Ömercan Tekin, Sakin Topalo ğlu, Seda Nur Bayraktaroglu, Taner Tags: Original Article: Endocrine Care Source Type: research
Acute Glycemic Variability and Functional Outcome in Patients with
Acute Ischemic Stroke: A Meta-Analysis
In conclusion, higher acute glycemic variability
may predict poor functional outcome within 3 months after AIS. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 13, 2022 Category: Endocrinology Authors: Lin, Jinbo Cai, Chunsheng Xie, Yituan Tags: Original Article: Endocrine Care Source Type: research
Triglyceride-Glucose Index and the Prognosis of Patients with Acute
Ischemic Stroke: A Meta-Analysis
In conclusion, higher
TyG index is a predictor of all-cause mortality and poor functional outcome in
patients with acute IS, and TyG index may be useful for prognostic evaluation in
these patients. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 13, 2022 Category: Endocrinology Authors: Ma, Xueling Han, Yuijia Jiang, Lai Li, Man Tags: Original Article: Endocrine Care Source Type: research
The Relationship Between Baseline Cortisol Levels and Surgery Method
of Primary Bilateral Macronodular Adrenal Hyperplasia
Horm Metab Res 2022; 54: 354-360 DOI: 10.1055/a-1850-2169Aim was to explore the associations between baseline cortisol levels and surgery
method of primary bilateral macronodular adrenal hyperplasia (PBMAH). We
retrospectively reviewed the clinical features and management of 30 patients (18
females and 12 males) who were diagnosed with PBMAH in our center between 2005
and 2019. Based on surgery method, we divided the patients into two groups:
unilateral adrenalectomy (UA) group; and bilateral adrenalectomy (BA) group.
Serum cortisol rhythm and 24-hour urinary free...
Source: Hormone and Metabolic Research - June 13, 2022 Category: Endocrinology Authors: Gao, Jie Yu, Zhongwei Sun, Fukang Xu, Bilin Zhang, Cuiping Wang, Hongping Lu, Jun Lei, Tao Tags: Original Article: Endocrine Care Source Type: research
Rare Metabolic and Endocrine Diseases with Cardiovascular
Involvement: Insights from Cardiovascular Magnetic Resonance – A
Review
This article reviews the
cardiovascular involvement of the most well-known rare metabolic and endocrine
diseases and their diagnostic approach through the lens of cardiovascular
magnetic resonance (CMR) imaging and its prognostic role, highlighting its
fundamental value compared to other imaging modalities. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - June 13, 2022 Category: Endocrinology Authors: Christidi, Aikaterini Mavrogeni, Sophie I. Tags: Review Source Type: research
Correction: Precision Medicine Approach for Cardiometabolic Risk Factors in
Therapeutic Apheresis
Horm Metab Res 2022; 54: e3-e3 DOI: 10.1055/a-1840-6523 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 11, 2022 Category: Endocrinology Authors: Yin, X. Takov, K. Straube, R. Voit-Bak, K. Graessler, J. Julius, U. Tselmin, S. Rodionov, Roman N. Barbir, M. Walls, M. Theofilatos, K. Mayr, M. Bornstein, S.R. Tags: Erratum Source Type: research
The Negative Association Between NAFLD Severity and CKD in a
Non-Diabetic Gouty Population
In conclusion, the presence and severity of NAFLD were
negatively associated with the risk of CKD in the non-diabetic gouty
population. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 9, 2022 Category: Endocrinology Authors: Huang, Yajing Zhou, Yue Wang, Yahao Chi, Jingwei Lv, Wenshan Wang, Yangang Chen, Ying Tags: Original Article: Endocrine Care Source Type: research
Uric Acid and Cognitive Impairment in Patients with Acute Ischemic
Stroke: A Meta-Analysis
Horm Metab Res 2022; 54: 316-324 DOI: 10.1055/a-1798-0387Serum uric acid (UA) has been suggested to be correlated with outcomes after
stroke. We performed a meta-analysis to evaluate the association between serum
UA and post-stroke cognitive impairment (PSCI) in patients with acute ischemic
stroke (AIS). Relevant observational studies were identified by search of
electronic databases including PubMed, Embase, and Web of Science. A
randomized-effect model incorporating the possible between-study heterogeneity
was used to pool the results. Overall, eleven studies wi...
Source: Hormone and Metabolic Research - May 9, 2022 Category: Endocrinology Authors: Yan, Xue Ren, Zhong Wen, Quan Jin, Xi Wang, Ying Zhang, Weimin Tags: Original Article: Endocrine Care Source Type: research
Adrenal Surgery in the Era of Multidisciplinary Endocrine Tumor
Boards
In conclusion, the endocrine tumor board
provided an excellent adherence to the guidelines with most surgeries being
performed either for functional or malignant tumors. In nonfunctional tumors
with history of extra adrenal cancer, CT guided biopsy might be considered for
obviating surgery. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 9, 2022 Category: Endocrinology Authors: Chiapponi, Costanza Santos, Daniel Pinto Dos Hartmann, Milan Janis Michael Schmidt, Matthias Faust, Michael Wahba, Roger Bruns, Christiane Josephine Schultheis, Anne Maria Alakus, Hakan Tags: Original Article: Endocrine Care Source Type: research
Exploration of Core Genes in ACTH-Independent Macronodular Adrenal
Hyperplasia
In conclusion, the 3 core genes, FOS, FOSB, and DUSP1,
identified here might be potential biomarkers for AIMAH, and the current study
is of guiding significance for clinical diagnosis and treatment of this
disease. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - May 9, 2022 Category: Endocrinology Authors: Li, Junwu Wang, Yunhui Li, Qinke Zhang, Ronggui Tags: Original Article: Endocrine Care Source Type: research
Physiological Functions of FBW7 in Metabolism
Horm Metab Res 2022; 54: 280-287 DOI: 10.1055/a-1816-8903FBW7 is the recognition subunit of the SCF (Skp1-Cullin1-F-box proteins) E3
ubiquitin ligase complex, and it determines the specificity of the SCF
substrate. SCFFBW7 is a recognized tumor suppressor because of its ability to
degrade many proto-oncogenic substrates. Recent studies have shown that FBW7
plays a key role in metabolism by targeting the degradation of critical
regulators involved in cellular metabolism in a ubiquitin-dependent manner.
Here, we review recent studies, which highlight the important r...
Source: Hormone and Metabolic Research - May 9, 2022 Category: Endocrinology Authors: Zhang, Jianmei Kong, De-huan Huang, Xiaocheng Yu, Rongbo Yang, Yachao Tags: Review Source Type: research
