Investigation of the Relationship Between Autoimmune and Nodular Goiter in Patients with Euthyroid Polycystic Ovary Syndrome and Their Phenotypes
Horm Metab Res 2022; 54: 396-406 DOI: 10.1055/a-1825-0316Polycystic ovary syndrome (PCOS) is an endocrine disorder that frequently affects
women of reproductive age. In PCOS, the incidence of thyroid diseases has
increased in addition to reproductive and metabolic problems. To compare thyroid
nodule, volume, autoimmunity, and thyroid function tests of euthyroid PCOS and
its phenotypes. The files of 178 patients with PCOS aged 18–45 years and
92 patients with no disease who were matched for body mass index were
retrospectively scanned. Women with PCOS were divided into four phenotypes,
ABCD. Anti-TPO titer and prevalence, fT3, and thyroid volume were higher in the
PCOS group compared with the control group in terms of anti-Tg levels, presence
of nodules, and the number of nodules. There was no statistical difference
between the PCOS group and the healthy controls. The number of nodules of
1 cm and above was found to be higher only in patients with PCOS
compared with the control group. When the phenotypes were examined, thyroid
dysfunction features were found in phenotype A, which was the most prominent.
Thyroid autoimmunity, thyroid volume, and the number of nodules larger than
1 cm increased in patients with PCOS compared with controls. This
situation is thought to be caused by the reproductive and metabolic prop...
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Altunta ş, Seher Çetinkaya G üneş, Mutlu Tags: Original Article: Endocrine Care Source Type: research
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