A Century After the Description of “Hormones”, Our
Golden Jubilee Celebration Goes on with What is New in Endocrine Oncology: And a
Lot is New!
Horm Metab Res 2020; 52: 551-552 DOI: 10.1055/a-1217-1529About 3000 thousand years ago Marcus Aurelius said: “Time is a sort of
river of passing events, and strong is its current; no sooner is a thing brought
to sight than it is swept by and another takes its place, and this too will be
swept away…” 1. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - August 12, 2020 Category: Endocrinology Authors: Stratakis, Constantine A. Tags: Editorial Source Type: research
Severe Hypocalcemia and Transient Hypoparathyroidism After
Hyperthermic Intraperitoneal Chemotherapy
Horm Metab Res DOI: 10.1055/a-1220-6971Dear Editors,Hypocalcemia is not unusual in patients hospitalized for critical illness and has
also been described after general surgery in addition to head and neck surgical
procedures 1
2
3. Hypocalcemic events commonly
occur in the setting of massive blood transfusion, albumin deficiency, vitamin D
deficiency, and/or hypomagnesemia. In the absence of these factors, only
slight decreases in calcium levels within the normal range have been reported during
surgical procedures 1. Cytoreductive surgery
with ...
Source: Hormone and Metabolic Research - August 6, 2020 Category: Endocrinology Authors: Tharmalingam, Senthuran Reddy, Sanjay Sharda, Pankaj Koch, Christian A. Tags: Letter to the Editor Source Type: research
No Independent Association of Circulating Fetuin-A with Insulin
Sensitivity in Young Women
Horm Metab Res DOI: 10.1055/a-1216-4405Animal data link high circulating fetuin-A to low insulin sensitivity and
observational studies identify the hepatokine as a marker of future incident
type 2 diabetes mellitus in humans. However, a recent, well-powered Mendelian
randomization study finds no causal role. We therefore tested in a
deeply-phenotyped human cohort if circulating fetuin-A correlates independently
with insulin sensitivity and how it relates to the metabolic syndrome and
ectopic fat deposition. We analyzed data from 290 young women with and without
...
Source: Hormone and Metabolic Research - August 5, 2020 Category: Endocrinology Authors: Reif, Sabrina Moschko, Sarah Gar, Christina Ferrari, Uta Hesse, Nina Sommer, Nora N. Sei ßler, Jochen Lechner, Andreas Tags: Endocrine Care Source Type: research
Hyperprolactinemia in Acromegaly is Related to Prolactin Secretion by
Somatolactotroph Tumours
Horm Metab Res DOI: 10.1055/a-1207-1132The aim of this study is to assess differences in patient characteristics,
tumour characteristics and hormone levels between acromegalic patients with
and without hyperprolactinemia. 44 patients of the University Hospital of
Brussels, Belgium with acromegaly who were diagnosed between January 2007
and July 2018 were included in this study. Nineteen patients were classified
in the hyperprolactinemia group and 25 patients were classified in the
normoprolactinemia group. No significant differences between acromegalic...
Source: Hormone and Metabolic Research - August 4, 2020 Category: Endocrinology Authors: Van Laethem, Delphine Michotte, Alex Cools, Wilfried Velkeniers, Brigitte Unuane, David Andreescu, C. E. Bravenboer, Bert Tags: Endocrine Care Source Type: research
Effect of KCNH6 on Hepatic Endoplasmic Reticulum Stress and Glucose
Metabolism
Horm Metab Res DOI: 10.1055/a-1177-6814Adult patients with a dysfunctional ether-a-go-go 2 (hERG2) protein, which is
encoded by the KCNH6 gene, present with hyperinsulinemia and
hyperglycemia. However, the mechanism of KCNH6 in glucose metabolism
disorders has not been clearly defined. It has been proposed that sustained
endoplasmic reticulum (ER) stress is closely concerned with hepatic insulin
resistance and inflammation. Here, we demonstrate that Kcnh6 knockout
(KO) mice had impaired glucose tolerance and increased levels of hepatic
apoptosis, in addi...
Source: Hormone and Metabolic Research - August 3, 2020 Category: Endocrinology Authors: Lu, Jing Shen, Han Li, Qi Xiong, Feng-Ran Yuan, Ming-Xia Yang, Jin-Kui Tags: Endocrine Research Source Type: research