Association Between the Variability of Glycated Hemoglobin and
Retinopathy in Patients with Type 2 Diabetes Mellitus: A
Meta-Analysis
In conclusion,
higher HbA1c variability may be associated with an increased risk of retinopathy
in patients with T2DM. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - October 12, 2022 Category: Endocrinology Authors: Zhai, Liping Lu, Jun Cao, Xinjian Zhang, Jun Yin, Yong Tian, Hu Tags: Original Article: Endocrine Care Source Type: research
Adipocyte-Derived Exosomal LINC00968 Promotes Mouse Retina
Microvascular Endothelial Cell Dysfunction in a High-Glucose Environment by
Modulating the miR-361 –5p/TRAF3 Axis
In conclusion, our results indicated
that in an H-glu environment, adipocyte exosomes damage microvascular
endothelial cells via a LINC00968/miR-361–5p/TRAF3
signaling pathway, which could possibly serve as a target for treating
diabetes-obesity-triggered microvascular complications. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - October 10, 2022 Category: Endocrinology Authors: He, Wenjing Lin, Anhua Wang, Chenxiu Tags: Original Article: Endocrine Research Source Type: research
Associations of PNPLA3 rs738409 Polymorphism with Plasma Lipid
Levels: A Systematic Review and Meta-Analysis
Horm Metab Res 2022; 54: 686-695 DOI: 10.1055/a-1929-1677Accumulating evidence has shown that the rs738409 polymorphism of patatin-like
phospholipase domain-containing 3 (PNPLA3) is associated with non-alcoholic
fatty liver disease (NAFLD). Since NAFLD has been reported to be associated with
lipid metabolism, this study is conducted to explore whether the rs738409
polymorphism of PNPLA3 was associated with lipid levels. By searching PubMed and
the Cochrane database from May 31, 2020, to June 30, 2021. Sixty-three studies
(81 003 subjects) were included for the ana...
Source: Hormone and Metabolic Research - October 7, 2022 Category: Endocrinology Authors: Luo, Zhi Liu, Yang Li, Hang Zhou, Yawen Peng, Yuanyuan Lin, Xuan Fang, Ying Wan, Jing Wei, Baozhu Tags: Original Article: Endocrine Care Source Type: research
Association Of Blood Lipocalin-2 Levels with Gestational Diabetes
Mellitus: A Systematic Review and Meta-Analysis
This study found that GDM showed
higher blood LCN2 levels than controls. However, caution is warranted on the
interpretation of these findings. Standardized LCN2 measurement methods and
longitudinal studies are required to disentangle and better understand the
relationships observed. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - October 7, 2022 Category: Endocrinology Authors: Zhu, Jing Jiang, Shuai Jiang, Xiaohong Luo, Kaiming Huang, Xiaolin Hua, Fei Tags: Original Article: Endocrine Care Source Type: research
Relations Between Body Fat Mass and Insulin Resistance in Non-Obese
Patients with Idiopathic Hypogonadotropic Hypogonadism and Normal Glucose
Tolerance
Horm Metab Res 2022; 54: 671-676 DOI: 10.1055/a-1933-3009The purpose of this study was to investigate the relationship between body fat
mass and insulin resistance in non-obese patients with idiopathic
hypogonadotropic hypogonadism (IHH) and normal glucose tolerance. A total of 42
patients with IHH and normal glucose tolerance, and BMI lower than
28 kg/m2 were recruited. Patients were required
to have a normal glucose tolerance test for inclusion in the study. Ten Healthy
subjects were recruited as control group. Laboratory studies included fasting
i...
Source: Hormone and Metabolic Research - October 7, 2022 Category: Endocrinology Authors: Yang, Xubin Chen, Xueyan Xu, Huan Deng, Hongrong Yao, Bin Xu, Wen Lin, Qiongyan Tags: Original Article: Endocrine Care Source Type: research
Effect of Cabergoline Treatment on Disease Control in Acromegaly
Patients
Horm Metab Res 2022; 54: 664-670 DOI: 10.1055/a-1930-6585The aim of this study was to evaluate the efficacy of cabergoline in normalizing
plasma IGF-I levels in acromegaly patients with elevated IGF-I levels after
surgery and/or SRL therapy. Acromegaly patients (n: 143) were evaluated
retrospectively. Patients with elevated IGF-I levels after surgery
and/or SRLs therapy and a fixed dose of SRLs treatment for the last six
months with no history of radiotherapy in the last three years were included in
the study (n: 12). Previous treatment regimens, baseline PRL and ...
Source: Hormone and Metabolic Research - October 7, 2022 Category: Endocrinology Authors: Hacisahinogullari, Hulya Yalin, Gulsah Yenidunya Selcukbiricik, Ozlem Soyluk Gul, Nurdan Bilgic, Bilge Uzum, Ayse Kubat Tanakol, Refik Aral, Ferihan Tags: Original Article: Endocrine Care Source Type: research
Knockdown of Endogenous Nucb2/Nesfatin-1 in the PVN Leads to
Obese-Like Phenotype and Abolishes the Metformin- and Stress-Induced Thermogenic
Response in Rats
Horm Metab Res DOI: 10.1055/a-1926-7280Nesfatin-1, the cleavage product of nucleobindin-2, is an anorexigenic peptide
and major regulator of energy homeostasis. Beyond reducing food intake and
increasing energy expenditure, it is also involved in regulating the stress
response. Interaction of nucleobindin-2/nesfatin-1 and glucose
homeostasis has been observed and recent findings suggest a link between the
action of the antidiabetic drug metformin and the nesfatinergic system. Hence,
this study aimed to clarify the role of nucleobindin-2/nesfatin-1 in the
...
Source: Hormone and Metabolic Research - October 4, 2022 Category: Endocrinology Authors: Stephan, Daniel Taege, Natalie Dore, Riccardo Folberth, Julica J öhren, Olaf Schwaninger, Markus Lehnert, Hendrik Schulz, Carla Tags: Original Article: Endocrine Research Source Type: research
Adipose Tissue Dysfunction: Impact on Metabolic
Changes?
Horm Metab Res DOI: 10.1055/a-1922-7052Adipose tissue is a metabolically dynamic organ that is the primary site of
storage for excess energy, but it serves as an endocrine organ capable of
synthesizing a number of biologically active compounds that regulate metabolic
homeostasis. However, when the capacity of expansion of this tissue exceeds,
dysfunction occurs, favoring ectopic accumulation of fat in the visceral, which
has been implicated in several disease states, most notably obesity. This review
highlights the mechanisms involved in the structure of adipose t...
Source: Hormone and Metabolic Research - September 29, 2022 Category: Endocrinology Authors: Morais, Jennifer Beatriz Silva Dias, Thaline Millany da Silva Cardoso, Bruna Emanuele Pereira de Paiva Sousa, Mickael Sousa, Thayanne Gabryelle Visgueira de Ara újo, Diana Stefany Cardoso de Marreiro, Dilina do Nascimento Tags: Review Source Type: research
Tripartite Motif Containing 26 is a Positive Predictor for
Endometrial Carcinoma Patients and Regulates Cell Survival in Endometrial
Carcinoma
Horm Metab Res DOI: 10.1055/a-1926-7364Functioning as an E3 ubiquitin ligase, tripartite motif containing 26 (TRIM26)
can regulate the tumor behavior and the relevant inflammatory immune response.
Endometrial carcinoma is a major gynecological malignant tumor in the world,
while no relevant research has been performed. KMplot, a web-based survival
analysis tool, demonstrated that TRIM26 expression was positively correlated
with the overall survival in gynecological tumors, such as ovarian, cervical,
and endometrial cancer. The relatively low expression of TRIM26 w...
Source: Hormone and Metabolic Research - September 15, 2022 Category: Endocrinology Authors: Lu, Tanmin Wu, Yu Tags: Original Article: Endocrine Research Source Type: research
Geriatric Nutritional Risk Index and the Prognosis of Patients with
Stroke: A Meta-Analysis
In conclusion, a low GNRI is associated with poor functional and
survival outcomes in patients after stroke. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - September 7, 2022 Category: Endocrinology Authors: Hu, Jun Chen, Ting Wang, Ziyue Chen, Xuhui Lin, Kaihua Zhang, Guogao Wu, Jun Tags: Original Article: Endocrine Care Source Type: research
Serum Metabolomic Signature Predicts Ovarian Response to Controlled
Stimulation
Horm Metab Res 2022; 54: 625-632 DOI: 10.1055/a-1882-3967In in vitro fertilization (IVF), it is meaningful to find novel biomarkers
predicting ovarian response in advance. The aim of the study was to identify
serum metabolomics predicting ovarian response after controlled ovarian
stimulation (COS). Blood samples collected at the start of pituitary
downregulation and on the fifth day after COS using Liquid chromatography-tandem
mass spectrometry (LC-MS/MS) methods were analyzed to quantify
metabolites. Demographic data were calculated with SPSS version 22.0 softwar...
Source: Hormone and Metabolic Research - September 7, 2022 Category: Endocrinology Authors: Mu, Xin Pei, Mei-li Zhu, Feng Shi, Juan Zi Liu, Peijun Tags: Original Article: Endocrine Research Source Type: research
Geriatric Nutritional Risk Index as a Prognostic Factor of Patients
with Non-Small Cell Lung Cancer: A Meta-Analysis
In conclusion, a lower GNRI in patients with NSCLC may be a
predictor of poor survival. Nutritional status indicated by GNRI may be
important for the prognostic prediction of patients with NSCLC. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - September 7, 2022 Category: Endocrinology Authors: Yang, Ming Liu, Zhaohui Li, Guojing Li, Bing Li, Chao Xiao, Lianbo Zhou, Jiwu Tags: Original Article: Endocrine Care Source Type: research
Homocysteine and the Mortality of Critically Ill Patients: A
Meta-Analysis
Horm Metab Res 2022; 54: 593-603 DOI: 10.1055/a-1897-5992Prevalence of hyperhomocysteinemia (HHcy) is high in critically ill patients.
However, the association between serum homocysteine level and outcomes of the
critically ill patients remains unknown. We performed a meta-analysis of cohort
studies to comprehensively evaluate the above association. Relevant cohort
studies were identified by search of electronic databases including PubMed,
Embase, Web of Science, Wanfang, and CNKI from the inception of the databases to
February 5, 2022. A randomized-effect model i...
Source: Hormone and Metabolic Research - September 7, 2022 Category: Endocrinology Authors: Yuan, Fawei Zheng, Kun Tags: Original Article: Endocrine Care Source Type: research
The Potential of Electrical Stimulation and Smart Textiles for
Patients with Diabetes Mellitus
Horm Metab Res 2022; 54: 583-586 DOI: 10.1055/a-1892-6489Diabetes mellitus is one of the most frequent diseases in the general population.
Electrical stimulation is a treatment modality based on the transmission of
electrical pulses into the body that has been widely used for improving wound
healing and for managing acute and chronic pain. Here, we discuss recent
advancements in electroceuticals and haptic/smart devices for quality of
life and present in which patients and how electrical stimulation may prove to
be useful for the treatment of diabetes-related comp...
Source: Hormone and Metabolic Research - September 7, 2022 Category: Endocrinology Authors: Engler, Babette Tselmin, Sergey Ziehl, Doreen Weigmann, Ingo Birkenfeld, Andreas Bornstein, Stefan R. Barthel, Andreas Drechsel, Tina Zippenfennig, Claudio Milani, Thomas Perakakis, Nikolaos Tags: Review Source Type: research
Immune Checkpoint Inhibitor Therapy in Neuroendocrine Tumors
Horm Metab Res DOI: 10.1055/a-1908-7790Neuroendocrine tumors (NETs) occur in various regions of the body and present with complex clinical and biochemical phenotypes. The molecular underpinnings that give rise to such varied manifestations have not been completely deciphered. The management of neuroendocrine tumors (NETs) involves surgery, locoregional therapy, and/or systemic therapy. Several forms of systemic therapy, including platinum-based chemotherapy, temozolomide/capecitabine, tyrosine kinase inhibitors, mTOR inhibitors, and peptide receptor radionuclide therapy have been extensively studied and implemented in the ...
Source: Hormone and Metabolic Research - September 2, 2022 Category: Endocrinology Authors: Gubbi, Sriram Vijayvergia, Namrata Yu, Jian Q KLUBO-GWIEZDZINSKA, JOANNA Koch, Christian Tags: Review Source Type: research
