The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links
The objective of this literature review is to examine the impact of bariatric surgery on bone and its main metabolic links, and to analyze the latest findings regarding the risk of fracture among patients submitted to bariatric surgery. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - March 11, 2022 Category: Endocrinology Authors: Mendon ça, Fernando Soares, Raquel Carvalho, Davide Freitas, Paula Tags: Review Source Type: research

Comparison of Continuous Glucose Monitoring in Cystic Fibrosis Patients With or Without Pancreatic Exocrine Insufficiency
This study aimed to compare continuous glucose monitoring (CGM) in cystic fibrosis (CF) according to pancreatic exocrine status. CGM and oral glucose tolerance testing (OGTT) were realized annually over five years in people with CF (pwCF) aged≥10 years without cystic fibrosis-related diabetes (CFRD). CGM parameters in patients with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and newly diagnosed CFRD were compared according to presence of pancreatic sufficiency (PS) or insufficiency (PI). Overall, 547 OGTTs and 501 CGMs were performed in 147...
Source: Hormone and Metabolic Research - March 10, 2022 Category: Endocrinology Authors: Rakotoarisoa, Luc Weiss, Laurence Lefebvre, Fran çois Porzio, Michele Ravoninjatovo, Bruno Abely, Michel Boucher, Isabelle Danner Dubois, S éverine Troussier, Fran çoise Gilles, Rault Prevotat, Anne Kessler, Laurence Tags: Original Article: Endocrine Care Source Type: research

Comparison of continuous glucose monitoring in cystic fibrosis patients with or without pancreatic exocrine insufficiency
Conclusion: CGM revealed significant different glucose tolerance abnormalities in PI versus PS, which were undetected by standard 2-hour OGTT glucose. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - March 10, 2022 Category: Endocrinology Authors: Rakotoarisoa, Luc Weiss, Laurence Lefebvre, Fran çois Porzio, Michele Ravoninjatovo, Bruno Abely, Michel Danner Boucher, Isabelle Dubois, S éverine Troussier, Fran çoise Gilles, Rault Prevotat, Anne Kessler, Laurence Tags: Original Article: Endocrine Care Source Type: research

Adipokine ZAG Alters Depression-Like Behavior by Regulating Oxidative Stress in Hippocampus
Horm Metab Res DOI: 10.1055/a-1759-3554Zinc-α2-glycoprotein (ZAG) is an adipokine involved in body metabolism, and now it has been shown to be present in the brain and play a role in some neurological diseases such as epilepsy and Alzheimer’s disease. In the present study, we employed ZAG knockout (KO) mice to investigate the effects of ZAG on behaviors after fasting and in vitro used overexpression (OV) ZAG in HT-22 cells to further clarify the possibly underlying mechanism. The results showed that ZAG exists widely in the brain tissues of mice and significant...
Source: Hormone and Metabolic Research - March 7, 2022 Category: Endocrinology Authors: Sun, Huangbing Ma, Fuli Chen, Wenjing Yang, Xiaojing Tags: Original Article: Endocrine Research Source Type: research

Correction: Thyroid Hormone Resistance: Multicentrical Case Series Study
Horm Metab Res 2022; 54: e1-e1 DOI: 10.1055/a-1769-7396 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - February 24, 2022 Category: Endocrinology Authors: Santos Mata, Maria Angeles Ariza Jimenez, Ana Belen Macias Lopez, Francisco de la Camara Mora ño, Carmen Tags: Erratum Source Type: research

Silencing LncRNA PVT1 Reverses High Glucose-Induced Regulation of the High Expression of PVT1 in HRMECs by Targeting miR-128-3p
Horm Metab Res 2022; 54: 119-125 DOI: 10.1055/a-1730-5091This paper aims to discuss the possibility of lncRNA PVT1 as a diagnostic biomarker for diabetic retinopathy (DR) and explore the underlying mechanism. Real-time quantitative polymerase chain reaction (RT-qPCR) was selected to determine the expression level of lncRNA PVT1 in the serum of all subjects. The receiver operating characteristic (ROC) curve reflected the diagnostic significance of PVT1 for DR patients. The Cell Counting Kit-8 (CCK-8) and Transwell assays were used to evaluate the effect of PVT1 exp...
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Wang, Xuyang Chen, Wangling Lao, Wei Chen, Yunxin Tags: Endocrine Research Source Type: research

miR-551b is Associated with the Poor Prognosis and Malignant Development of Papillary Thyroid Cancer Through Regulating ERBB4
In conclusion, miR-551b could predict the poor prognosis of PTC patients and serve as a tumor promoter via suppressing ERBB4. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Wang, Jian Liu, Haibo Tags: Endocrine Research Source Type: research

Association Between Prediabetes and Osteoarthritis: A Meta-Analysis
Horm Metab Res 2022; 54: 104-112 DOI: 10.1055/a-1730-5251Some studies have suggested that diabetes may be a risk factor for osteoarthritis. However, whether prediabetes is also associated with osteoarthritis has not been comprehensively examined. We performed a meta-analysis to evaluate the relationship between prediabetes and osteoarthritis. This meta-analysis included relevant observational studies from Medline, Embase, and Web of Science databases. A random-effect model after incorporation of the intra-study heterogeneity was selected to pool the results. ...
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Li, Xi Zhou, Yong Liu, Jianxiu Tags: Endocrine Care Source Type: research

The Scope of HbA1c Variability and Risk of Vascular Complications Among Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Prospective Studies
Horm Metab Res 2022; 54: 94-103 DOI: 10.1055/a-1730-4904Glycated hemoglobin (HbA1c) variability is emerging as an indicator of long-term glycemic control, which may play a significant role during vascular complications. We conducted a systematic review and meta-analysis to assess the association between the scope of HbA1c variability and vascular complications in patients with type 2 diabetes mellitus. PubMed and Embase were searched for studies that evaluated the association of HbA1c variability with vascular complications in patients with type 2 diabetes. Two re...
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Guo, Kai Zhao, Qian Wang, Meng Lu, Yuchun Wo, Meihong Zhou, Xiaoyan Ying, Changjiang Tags: Endocrine Care Source Type: research

Long-Term Glycemic Variability and Risk of Cardiovascular Events in Type 2 Diabetes: A Meta-Analysis
In conclusion, increased long-term glycemic variability may be an independent risk factor for cardiovascular events in T2DM patients. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Wang, Ting Zhang, Xin Liu, Jian Tags: Endocrine Care Source Type: research

Effects of Thyroperoxidase Antibody and Thyroglobulin Antibody on Maternal and Neonatal Outcomes in Pregnant Women
In conclusion, pregnant women with positive thyroid auto-antibodies had an increased risk of PPT and a reduced rate of euthyroidism at 2 and 3 years postpartum. TPOAb is associated with the incidence of PROM. Both of TPOAb and TgAb were independent risk factors for PPT. TgAb deserves more attention when studying autoimmune thyroid disease (AITD) combined with pregnancy. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Wang, Li Tang, Yi Yuan, Yi Yu, Lin Jin, Bai Xia, Jun Yuan, Qingxin Tags: Endocrine Care Source Type: research

Thyroid Hormone Resistance: Multicentrical Case Series Study
In conclusion, a better understanding of RTHS, its prompt molecular diagnosis and genetic counseling, could avoid unnecessary tests and inappropriate treatments. [...] Georg Thieme Verlag Rüdigerstraße 14,70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Mata, Maria Angeles Santos Jimenez, Ana Belen Ariza Lopez, Francisco Macias de la Camara Mora ño, Carmen Tags: Endocrine Care Source Type: research

Clinical Spectrum of Adrenal Cushing ’s Syndrome and the Caution for Interpretation of Adrenocorticotrophic Hormone: A Single-Center Experience
Conclusions:  Cortisol-secreting ACC and ACA most often present with mass effects and florid CS, respectively. Baseline HU has low sensitivity to differentiate cortisol-secreting ACA from ACC. Plasma ACTH measured by Seimens Immulite is often unsuppressed, especially in ACC patients, which can be addressed by measuring ACTH by more accurate assays. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - February 7, 2022 Category: Endocrinology Authors: Gosavi, Vikrant Lila, Anurag Memon, Saba Samad Sarathi, Vijaya Thakkar, Kunal Dalvi, Abhay Malhotra, Gaurav Prakash, Gagan Patil, Virendra Shah, Nalini S. Bandgar, Tushar Tags: Endocrine Care Source Type: research

Incretins Enhance PGF2 α-Induced Synthesis of IL-6 and Osteoprotegerin in Osteoblasts
Horm Metab Res 2022; 54: 42-49 DOI: 10.1055/a-1713-7967Incretins including glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), which are secreted from the small intestine after oral food ingestion, are currently well-known to stimulate insulin secretion from pancreatic β-cells and used for the treatment of type 2 diabetes mellitus. We have previously reported that prostaglandin F2α (PGF2α) stimulates the synthesis of interleukin-6 (IL-6) and osteoprotegerin in osteoblast-like MC3T3-E1 cells, and that IL-6 and oste...
Source: Hormone and Metabolic Research - January 5, 2022 Category: Endocrinology Authors: Hioki, Tomoyuki Kuroyanagi, Gen Fujita, Kazuhiko Sakai, Go Kawabata, Tetsu Kim, Woo Tachi, Junko Matsushima-Nishiwaki, Rie Iida, Hiroki Kozawa, Osamu Tokuda, Haruhiko Tags: Endocrine Research Source Type: research

The Triglycerides and Glucose Index is Negatively Associated with Insulin Secretion in Young Adults with Normal Weight
Horm Metab Res 2022; 54: 33-36 DOI: 10.1055/a-1713-7821Several studies have supported the usefulness of the triglycerides and glucose (TyG) index as a surrogate measure of insulin resistance; however, it has not been evaluated in insulin secretion. The aim of this study was to assess the association between the TyG index and insulin secretion in young adults with normal weight. Apparently healthy non-pregnant women and men, aged 18 to 23 years, were enrolled in a cross-sectional study. Overweight, obesity, pregnancy, smoking, alcohol consumption, diabetes, liver d...
Source: Hormone and Metabolic Research - January 5, 2022 Category: Endocrinology Authors: Simental-Mend ía, Luis E. G ómez-Díaz, Rita Wacher, Niels H. Guerrero-Romero, Fernando Tags: Endocrine Care Source Type: research