The Value of Visfatin in the Prediction of Metabolic Syndrome: A Systematic Review and Meta-Analysis
Horm Metab Res DOI: 10.1055/a-2051-6776Various studies have shown that visfatin may be connected to metabolic syndrome
(MS). However, epidemiological studies yielded conflicting outcomes. The purpose
of this article was to highlight the relationship between the plasma visfatin
level and MS risk by conducting a meta-analysis of available literature. A
comprehensive literature search of eligible studies was done up to January 2023.
Data were presented as standard mean difference (SMD). Observational
methodological meta-analysis was conducted to assess the relationships between
visfatin levels and MS. The visfatin levels between patients with MS or not were
calculated by SMD and 95% confidence interval (CI) using the
random-effects model. Funnel plot (visually inspect publication bias),
Egger’s linear regression test and Begger’s linear regression
test were applied to describe the risk of publication bias. A sensitivity
analysis was performed via sequentially omitting each of the study one by one.
In total, 16 eligible studies comprising 1016 cases and 1414 healthy controls
finally enrolled in the current meta-analysis for pooling meta-analysis.
Overall, the meta-analysis results revealed that visfatin levels in MS patients
were significantly greater than that of controls group (SMD: 0.60, 95%
CI=0.18–1.03...
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Jiang, Yingling Zhou, Lihua Tags: Original Article: Endocrine Care Source Type: research